MGE detailed information
MGE type: Integrative_Conjugative_Elements MGE length: 169340 bp
Accession: NC_010380 Location: 1028133..1197472 Organism: Streptococcus pneumoniae Hungary19A-6 Replicon: chromosome
Accession: NC_010380 Location: 1028133..1197472 Organism: Streptococcus pneumoniae Hungary19A-6 Replicon: chromosome
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SPH_RS13555 () | 1023175..1023432 | + | 258 | WP_001811716.1 | hypothetical protein | - |
| SPH_RS13560 () | 1023461..1023793 | + | 333 | WP_001811715.1 | hypothetical protein | - |
| SPH_RS05380 () | 1023829..1025052 | - | 1224 | WP_000222058.1 | peptidase T | - |
| SPH_RS05385 () | 1025207..1026301 | + | 1095 | WP_000709253.1 | ferrochelatase | - |
| SPH_RS05390 () | 1026343..1026720 | - | 378 | WP_000916795.1 | large conductance mechanosensitive channel protein MscL | - |
| SPH_RS05395 () | 1026802..1027233 | - | 432 | WP_000742999.1 | GtrA family protein | - |
| SPH_RS05400 () | 1027356..1027865 | + | 510 | WP_000737071.1 | QueT transporter family protein | - |
| SPH_RS05410 () | 1028622..1029698 | + | 1077 | WP_000542475.1 | aspartate-semialdehyde dehydrogenase | - |
| SPH_RS05415 () | 1029754..1030689 | + | 936 | WP_000121646.1 | 4-hydroxy-tetrahydrodipicolinate synthase | - |
| SPH_RS05420 () | 1030736..1032109 | - | 1374 | WP_000632715.1 | tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE | - |
| SPH_RS05425 () | 1032246..1032428 | - | 183 | WP_001117401.1 | 4-oxalocrotonate tautomerase | - |
| SPH_RS05430 () | 1032551..1033150 | + | 600 | WP_000068144.1 | thymidine kinase | - |
| SPH_RS05435 () | 1033140..1033619 | + | 480 | WP_000151327.1 | GNAT family N-acetyltransferase | - |
| SPH_RS05440 () | 1033629..1034708 | + | 1080 | WP_001028828.1 | peptide chain release factor 1 | - |
| SPH_RS05445 () | 1034708..1035547 | + | 840 | WP_000761907.1 | peptide chain release factor N(5)-glutamine methyltransferase | - |
| SPH_RS05450 () | 1035531..1036133 | + | 603 | WP_000969297.1 | threonylcarbamoyl-AMP synthase | - |
| SPH_RS05455 () | 1036135..1036566 | + | 432 | WP_000942936.1 | GNAT family N-acetyltransferase | - |
| SPH_RS05460 () | 1036628..1037884 | + | 1257 | WP_000575488.1 | serine hydroxymethyltransferase | - |
| SPH_RS05465 () | 1037892..1038866 | + | 975 | WP_000356089.1 | nucleoid-associated protein | - |
| SPH_RS05470 () | 1038866..1039480 | + | 615 | WP_000476375.1 | cell wall hydrolase Pmp23 | - |
| SPH_RS05475 () | 1039554..1040528 | + | 975 | WP_001227754.1 | DUF1002 domain-containing protein | - |
| SPH_RS05480 () | 1040602..1042233 | + | 1632 | WP_000914579.1 | 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD | - |
| SPH_RS05485 () | 1042447..1042680 | + | 234 | WP_000710795.1 | hypothetical protein | - |
| SPH_RS05490 () | 1042982..1043200 | + | 219 | WP_001207345.1 | helix-turn-helix transcriptional regulator | - |
| SPH_RS05495 () | 1043204..1043473 | + | 270 | WP_000175448.1 | hypothetical protein | - |
| SPH_RS05500 () | 1043593..1044618 | + | 1026 | WP_000790747.1 | iron-siderophore ABC transporter substrate-binding protein | - |
| SPH_RS05505 () | 1044608..1045615 | + | 1008 | WP_001244693.1 | Ferric enterobactin transport system permease protein FepD | VF |
| SPH_RS05510 () | 1045615..1046622 | + | 1008 | WP_001180357.1 | putative siderophore transport system permease protein YfhA | VF |
| SPH_RS05515 () | 1046622..1047416 | + | 795 | WP_000677521.1 | Petrobactin import ATP-binding protein FpuD | VF |
| SPH_RS12540 () | 1047804..1048193 | + | 390 | WP_074017679.1 | restriction endonuclease subunit S | - |
| SPH_RS13565 () | 1048159..1048485 | + | 327 | WP_164993578.1 | hypothetical protein | - |
| SPH_RS05530 () | 1049169..1049330 | + | 162 | WP_000368174.1 | hypothetical protein | - |
| SPH_RS05535 () | 1049422..1051101 | + | 1680 | WP_000031863.1 | Tn3 family transposase TnpR_ISAcsp1 | Transposase |
| SPH_RS05540 () | 1051369..1051935 | + | 567 | WP_000234983.1 | hypothetical protein | - |
| SPH_RS05545 () | 1052257..1052445 | + | 189 | WP_000179769.1 | hypothetical protein | - |
| SPH_RS05550 () | 1052507..1053265 | + | 759 | WP_000262036.1 | ATP-grasp domain-containing protein | - |
| SPH_RS05555 () | 1053323..1054177 | + | 855 | WP_000900015.1 | ADP-ribosylglycohydrolase family protein | - |
| SPH_RS05560 () | 1054289..1055173 | + | 885 | WP_000710115.1 | diacylglycerol kinase family lipid kinase | - |
| SPH_RS05565 () | 1055336..1057075 | + | 1740 | WP_000423457.1 | glycoside hydrolase family 13 protein | - |
| SPH_RS05575 () | 1057350..1057652 | + | 303 | WP_000500477.1 | hypothetical protein | - |
| SPH_RS05580 () | 1057708..1058136 | + | 429 | WP_000348721.1 | GNAT family N-acetyltransferase | - |
| SPH_RS12545 () | 1058194..1058803 | + | 610 | Protein_1065 | Type 1 glutamine amidotransferase-like domain-containing protein | - |
| SPH_RS05595 () | 1059085..1059333 | + | 249 | WP_001814426.1 | aminoglycoside phosphotransferase | - |
| SPH_RS12550 () | 1059438..1059740 | + | 303 | Protein_1067 | IS5 family transposase IS1381A | Transposase |
| SPH_RS05605 () | 1059896..1061125 | + | 1230 | WP_012291629.1 | FtsW/RodA/SpoVE family cell cycle protein | - |
| SPH_RS05610 () | 1061145..1063841 | + | 2697 | WP_000058183.1 | phosphoenolpyruvate carboxylase | - |
| SPH_RS05615 () | 1064254..1065258 | + | 1005 | WP_000792167.1 | hypothetical protein | VF |
| SPH_RS05620 () | 1065327..1066193 | + | 867 | WP_000637233.1 | ABC transporter permease | - |
| SPH_RS05625 () | 1066190..1066948 | + | 759 | WP_000125412.1 | ABC transporter ATP-binding protein | - |
| SPH_RS05630 () | 1067038..1068798 | + | 1761 | WP_000227864.1 | DNA primase | - |
| SPH_RS05635 () | 1068801..1069910 | + | 1110 | WP_000201898.1 | RNA polymerase sigma factor RpoD | - |
| SPH_RS05640 () | 1069924..1070253 | + | 330 | WP_000331928.1 | metal-sulfur cluster assembly factor | - |
| SPH_RS05645 () | 1070368..1071411 | + | 1044 | WP_012291610.1 | alpha-galactosylglucosyldiacylglycerol synthase | - |
| SPH_RS05650 () | 1071427..1072752 | + | 1326 | WP_001219433.1 | glycosyltransferase family 4 protein | - |
| SPH_RS05655 () | 1072781..1072957 | + | 177 | WP_016398151.1 | PspC domain-containing protein | - |
| SPH_RS05660 () | 1073016..1073150 | + | 135 | WP_000863859.1 | DUF4044 domain-containing protein | - |
| SPH_RS05665 () | 1073214..1074524 | + | 1311 | WP_023931670.1 | GTPase ObgE | - |
| SPH_RS05670 () | 1074534..1074692 | + | 159 | WP_001808548.1 | hypothetical protein | - |
| SPH_RS12555 () | 1074743..1075922 | - | 1180 | Protein_1082 | transposase | - |
| SPH_RS05685 () | 1077173..1078432 | + | 1260 | WP_001227085.1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | - |
| SPH_RS05690 () | 1078448..1078999 | + | 552 | WP_001028733.1 | GNAT family N-acetyltransferase | - |
| SPH_RS05695 () | 1078992..1080269 | + | 1278 | WP_000033830.1 | CBS-HotDog domain-containing transcription factor SpxR | - |
| SPH_RS05700 () | 1080285..1081145 | + | 861 | WP_000631543.1 | methionyl aminopeptidase | - |
| SPH_RS12565 () | 1081526..1082329 | + | 804 | Protein_1087 | IS5 family transposase | - |
| SPH_RS05720 () | 1082521..1084812 | + | 2292 | WP_000992881.1 | DNA helicase PcrA | - |
| SPH_RS05725 () | 1084855..1085535 | + | 681 | WP_000286922.1 | DNA repair protein RadC | - |
| SPH_RS05730 () | 1085532..1086221 | - | 690 | WP_000743316.1 | gamma-glutamyl-gamma-aminobutyrate hydrolase family protein | - |
| SPH_RS05735 () | 1086239..1086880 | - | 642 | WP_000653403.1 | redox-sensing transcriptional repressor Rex | - |
| SPH_RS05740 () | 1086963..1087178 | - | 216 | WP_000462488.1 | DUF4649 family protein | - |
| SPH_RS05745 () | 1087186..1087533 | - | 348 | WP_000863509.1 | DUF1831 domain-containing protein | - |
| SPH_RS05750 () | 1087538..1088653 | - | 1116 | WP_000639662.1 | cysteine desulfurase | - |
| SPH_RS05755 () | 1088663..1089622 | - | 960 | WP_001283813.1 | ribose-phosphate diphosphokinase | - |
| SPH_RS05760 () | 1089735..1090304 | - | 570 | WP_000681292.1 | CYTH domain-containing protein | - |
| SPH_RS05765 () | 1090432..1091103 | + | 672 | WP_000171678.1 | GTP pyrophosphokinase family protein | - |
| SPH_RS05770 () | 1091087..1091905 | + | 819 | WP_000799059.1 | NAD kinase | - |
| SPH_RS05775 () | 1091902..1092798 | + | 897 | WP_001210007.1 | RluA family pseudouridine synthase | - |
| SPH_RS05780 () | 1092842..1093816 | + | 975 | WP_000451584.1 | phosphate acetyltransferase | - |
| SPH_RS12570 () | 1094077..1095403 | - | 1327 | Protein_1101 | ISL3 family transposase | - |
| SPH_RS05800 () | 1095585..1095884 | - | 300 | WP_000981526.1 | YbaB/EbfC family nucleoid-associated protein | - |
| SPH_RS05805 () | 1096286..1096984 | + | 699 | WP_000509041.1 | DUF1275 domain-containing protein | - |
| SPH_RS05810 () | 1097172..1097486 | + | 315 | WP_000109141.1 | 50S ribosomal protein L21 | - |
| SPH_RS05815 () | 1097502..1097846 | + | 345 | WP_000613700.1 | ribosomal-processing cysteine protease Prp | - |
| SPH_RS05820 () | 1097863..1098156 | + | 294 | WP_000916509.1 | 50S ribosomal protein L27 | - |
| SPH_RS13215 () | 1098361..1098566 | - | 206 | Protein_1107 | ABC transporter substrate-binding protein | - |
| SPH_RS05830 () | 1099004..1099921 | + | 918 | WP_000587444.1 | bifunctional riboflavin kinase/FAD synthetase | - |
| SPH_RS05835 () | 1100014..1100862 | - | 849 | WP_000592056.1 | YitT family protein | - |
| SPH_RS05840 () | 1101004..1101843 | + | 840 | WP_000161400.1 | DegV family protein | - |
| SPH_RS05845 () | 1101950..1102225 | + | 276 | WP_001284644.1 | HU family DNA-binding protein | - |
| SPH_RS05850 () | 1102651..1104552 | + | 1902 | WP_000584923.1 | ABC-F family ATP-binding cassette domain-containing protein | - |
| SPH_RS05855 () | 1104555..1105418 | + | 864 | WP_012291596.1 | XRE/MutR family transcriptional regulator | - |
| SPH_RS05860 () | 1105498..1106676 | + | 1179 | WP_001083026.1 | MFS transporter | - |
| SPH_RS05865 () | 1106769..1108727 | + | 1959 | WP_001042601.1 | NAD-dependent DNA ligase LigA | - |
| SPH_RS05870 () | 1108839..1111118 | + | 2280 | WP_000283068.1 | type I pullulanase | - |
| SPH_RS05880 () | 1111663..1113087 | + | 1425 | WP_000199371.1 | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | - |
| SPH_RS05885 () | 1113570..1115498 | + | 1929 | WP_000370242.1 | 1,4-alpha-glucan branching protein GlgB | - |
| SPH_RS05890 () | 1115488..1116630 | + | 1143 | WP_000787276.1 | glucose-1-phosphate adenylyltransferase | - |
| SPH_RS05895 () | 1116620..1117759 | + | 1140 | WP_000687070.1 | glucose-1-phosphate adenylyltransferase subunit GlgD | - |
| SPH_RS05900 () | 1117756..1119189 | + | 1434 | WP_000697287.1 | glycogen synthase GlgA | - |
| SPH_RS13570 () | 1119248..1119619 | + | 372 | WP_001811698.1 | Phosphoserine phosphatase | VF |
| SPH_RS13575 () | 1119564..1119893 | + | 330 | WP_041864705.1 | HAD hydrolase family protein | - |
| SPH_RS05915 () | 1119902..1121017 | + | 1116 | WP_000706436.1 | glycerate kinase | - |
| SPH_RS05920 () | 1121014..1121460 | - | 447 | WP_000131076.1 | YueI family protein | - |
| SPH_RS05925 () | 1121624..1122928 | + | 1305 | WP_000022813.1 | phosphopyruvate hydratase | - |
| SPH_RS12580 () | 1123066..1123446 | - | 381 | WP_001817933.1 | tyrosine-type recombinase/integrase | - |
| SPH_RS12585 () | 1123412..1124257 | - | 846 | Protein_1128 | IS630 family transposase | - |
| SPH_RS13230 () | 1124428..1124583 | + | 156 | Protein_1129 | diacylglycerol kinase family lipid kinase | - |
| SPH_RS05940 () | 1124783..1128058 | + | 3276 | WP_000772379.1 | ATP-dependent nuclease subunit B | - |
| SPH_RS05945 () | 1128055..1131705 | + | 3651 | WP_000767219.1 | helicase-exonuclease AddAB subunit AddA | - |
| SPH_RS05950 () | 1131920..1133096 | + | 1177 | Protein_1132 | hypothetical protein | - |
| SPH_RS05955 () | 1133305..1138983 | + | 5679 | WP_000417124.1 | Immunoglobulin A1 protease | VF |
| SPH_RS12595 () | 1139035..1139202 | + | 168 | WP_079218411.1 | LPXTG cell wall anchor domain-containing protein | - |
| SPH_RS05960 () | 1139217..1140473 | - | 1257 | WP_000436627.1 | ISL3 family transposase IS1167 | Transposase |
| SPH_RS12600 () | 1141097..1141270 | + | 174 | WP_000159607.1 | hypothetical protein | - |
| SPH_RS05965 () | 1141267..1142046 | + | 780 | WP_000822767.1 | replication initiator protein A | - |
| SPH_RS05970 () | 1142145..1143503 | + | 1359 | WP_001210974.1 | DNA (cytosine-5-)-methyltransferase | - |
| SPH_RS05975 () | 1143487..1143936 | + | 450 | WP_000645884.1 | hypothetical protein | - |
| SPH_RS05980 () | 1143929..1144309 | + | 381 | WP_000566537.1 | hypothetical protein | - |
| SPH_RS05985 () | 1144322..1144555 | + | 234 | WP_000840778.1 | hypothetical protein | - |
| SPH_RS05990 () | 1144558..1145145 | + | 588 | WP_000821278.1 | CPBP family intramembrane metalloprotease | - |
| SPH_RS05995 () | 1145275..1145865 | + | 591 | WP_000227921.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | - |
| SPH_RS06000 () | 1145865..1146701 | + | 837 | WP_000492398.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| SPH_RS06005 () | 1146983..1147282 | + | 300 | WP_000869756.1 | hypothetical protein | - |
| SPH_RS06010 () | 1147272..1147760 | + | 489 | WP_000093686.1 | hypothetical protein | - |
| SPH_RS06015 () | 1147760..1149637 | + | 1878 | WP_012291586.1 | type IV secretory system conjugative DNA transfer family protein | - |
| SPH_RS06020 () | 1149658..1149900 | + | 243 | WP_000627868.1 | hypothetical protein | - |
| SPH_RS06025 () | 1149917..1150771 | + | 855 | WP_001054257.1 | conjugal transfer protein TrbL | - |
| SPH_RS06030 () | 1150825..1151184 | + | 360 | WP_001097589.1 | PrgI family protein | - |
| SPH_RS06035 () | 1151135..1153492 | + | 2358 | WP_000824174.1 | hypothetical protein | - |
| SPH_RS06040 () | 1153504..1156317 | + | 2814 | WP_000653465.1 | CHAP domain-containing protein | - |
| SPH_RS13580 () | 1156348..1156536 | - | 189 | WP_001860875.1 | hypothetical protein | - |
| SPH_RS06045 () | 1156609..1157130 | + | 522 | WP_164993579.1 | hypothetical protein | - |
| SPH_RS06050 () | 1157282..1157692 | + | 411 | WP_000387514.1 | thrombospondin type 3 repeat-containing protein | - |
| SPH_RS06055 () | 1157740..1163963 | + | 6224 | Protein_1156 | DEAD/DEAH box helicase family protein | - |
| SPH_RS06060 () | 1164038..1164322 | + | 285 | WP_000969639.1 | hypothetical protein | - |
| SPH_RS06065 () | 1164336..1164656 | + | 321 | WP_000998898.1 | hypothetical protein | - |
| SPH_RS06070 () | 1165386..1166423 | + | 1038 | WP_000429739.1 | hypothetical protein | - |
| SPH_RS06075 () | 1166468..1166866 | + | 399 | WP_000351508.1 | hypothetical protein | - |
| SPH_RS11990 () | 1167194..1168075 | + | 882 | WP_000451090.1 | GIY-YIG nuclease family protein | - |
| SPH_RS06085 () | 1168479..1169120 | + | 642 | WP_000933082.1 | hypothetical protein | - |
| SPH_RS06090 () | 1169130..1170215 | + | 1086 | WP_000401897.1 | toprim domain-containing protein | - |
| SPH_RS06095 () | 1170266..1170499 | + | 234 | WP_000152419.1 | hypothetical protein | - |
| SPH_RS06100 () | 1170496..1170879 | + | 384 | WP_000159215.1 | hypothetical protein | - |
| SPH_RS06105 () | 1170917..1171189 | + | 273 | WP_000495448.1 | hypothetical protein | - |
| SPH_RS06110 () | 1171260..1171736 | + | 477 | WP_000579597.1 | helix-turn-helix domain-containing protein | Antitoxin Detail |
| SPH_RS06115 () | 1171736..1172494 | + | 759 | WP_000405369.1 | zeta toxin family protein | Toxin Detail |
| SPH_RS06120 () | 1172970..1173758 | + | 789 | WP_000214003.1 | hypothetical protein | - |
| SPH_RS06125 () | 1173997..1174245 | + | 249 | WP_001814254.1 | hypothetical protein | - |
| SPH_RS06130 () | 1174416..1175135 | + | 720 | Protein_1171 | Chloramphenicol acetyltransferase | ARG |
| SPH_RS06135 () | 1175931..1176854 | - | 924 | WP_000417606.1 | protein rep | - |
| SPH_RS06140 () | 1177117..1177608 | + | 492 | WP_001086583.1 | phosphoribosylanthranilate isomerase | - |
| SPH_RS06145 () | 1177785..1179527 | + | 1743 | WP_000423944.1 | glycoside hydrolase family 13 protein | - |
| SPH_RS06150 () | 1179647..1179958 | + | 312 | WP_000420556.1 | hypothetical protein | - |
| SPH_RS06155 () | 1179962..1180696 | + | 735 | WP_000759784.1 | alpha/beta hydrolase | - |
| SPH_RS06160 () | 1181025..1181876 | + | 852 | WP_000201320.1 | Ribosome biogenesis GTPase A | VF |
| SPH_RS06165 () | 1181863..1182642 | + | 780 | WP_000201131.1 | ribonuclease HII | - |
| SPH_RS06170 () | 1182658..1184208 | + | 1551 | WP_000392538.1 | ClC family H(+)/Cl(-) exchange transporter | - |
| SPH_RS06175 () | 1184794..1185864 | + | 1071 | WP_000817860.1 | Tyrosine recombinase XerS ; Integrase | Integrase |
| SPH_RS12620 () | 1185974..1187322 | + | 1349 | WP_129559159.1 | IS3 family transposase | - |
| SPH_RS06190 () | 1187504..1188856 | - | 1353 | WP_000278520.1 | sodium-coupled multidrug efflux MATE transporter PdrM | - |
| SPH_RS06195 () | 1188867..1189127 | - | 261 | WP_001105920.1 | hypothetical protein | - |
| SPH_RS06200 () | 1189141..1190409 | - | 1269 | WP_000924526.1 | dihydroorotase | - |
| SPH_RS06205 () | 1190422..1190886 | - | 465 | WP_001135774.1 | 8-oxo-dGTP diphosphatase | - |
| SPH_RS06210 () | 1190896..1191549 | - | 654 | WP_000401331.1 | uracil-DNA glycosylase | - |
| SPH_RS06215 () | 1191611..1192303 | - | 693 | WP_000120620.1 | YjjG family noncanonical pyrimidine nucleotidase | - |
| SPH_RS06220 () | 1192428..1192646 | - | 219 | WP_000680090.1 | hypothetical protein | - |
| SPH_RS06225 () | 1192997..1194679 | - | 1683 | WP_012291581.1 | ABC transporter ATP-binding protein/permease | - |
| SPH_RS06230 () | 1194701..1195420 | - | 720 | WP_001244587.1 | Bacitracin transport ATP-binding protein BcrA | VF |
| SPH_RS06235 () | 1195555..1196295 | - | 741 | WP_000949748.1 | ABC transporter permease | - |
| SPH_RS06240 () | 1196467..1197102 | - | 636 | WP_000113541.1 | TetR/AcrR family transcriptional regulator | - |
| SPH_RS06245 () | 1197684..1198058 | - | 375 | WP_000534740.1 | PTS-dependent dihydroxyacetone kinase phosphotransferase subunit DhaM | - |
| SPH_RS06250 () | 1198058..1198633 | - | 576 | WP_001100274.1 | dihydroxyacetone kinase subunit L | - |
| SPH_RS06255 () | 1198655..1199644 | - | 990 | WP_000720686.1 | dihydroxyacetone kinase subunit DhaK | - |
| SPH_RS06260 () | 1199798..1200328 | + | 531 | WP_000168607.1 | dihydroxyacetone kinase transcriptional activator DhaS | - |
| SPH_RS06265 () | 1200325..1201314 | + | 990 | WP_000142824.1 | DhaKLM operon coactivator DhaQ | - |
| SPH_RS06270 () | 1201412..1201951 | - | 540 | WP_012291631.1 | ClbS/DfsB family four-helix bundle protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|