SecReT4
Effector Protein ID: 88658219
T4SS name [ID]VirB [493]
Gene symbol-
Locus tagECH_0767
StrainEhrlichia chaffeensis str. Arkansas
Repliconchromosome [GenBank: NC_007799] [Browse all T4SS(s) in this replicon]
Location [Strand]774594..776459 [+]
Producthypothetical protein
Effector typeProtein
DescriptonEtf-3
T4CP requirementT4CP Depedent
Target/Effectionunknown
UniProt IDQ2GG68
KEGG IDech:ECH_0767
PDB IDNA
Domain hit(s) vs Pfam NA
Protein Sequence: 621 a.a.     [Download]
>gi|88658219|ref|YP_507565.1| hypothetical protein ECH_0767 [Ehrlichia chaffeensis str. Arkansas]
MCNNAMLTKVQQRAAINNINLKQYIRDITLEKIDEALIDISNVIPLCIALMLDITPDFTSFRNEVTSMLE
EYKEWFIANGEAKMPLIDDRTSDTLWNSIKEIHTLYHKHQMSISSNDGINILDRIAFNSAHNTQDIIIDN
KLKYKIQYIILSSFIDQCFDTDTNPTTIYKTEILLLTSEIRSKITNKLKTTLFQYVQKKAFSSYAEHLRN
LYNIQASYVIEKNIDLLRTAEQFIGLKSIHILNQRTFRKINLLLDSGCEINVKCDIPTYTEIFLEISDIT
IFGTVYGSIFNKYGSITIIDAKEECSKNILSIFGTVSINGKIIKNNLPDIFTIPANFCRNIKHKTIITRQ
TDLCQAEKVITSFHPCDVINQKDPNGIRALNIELFHPNFQYHTVIASIGWPINKQNNTSTENAELLFHNI
IHNANHLNIIDNISKNQRLPNTFFNDSIPMFIHNIRITNKQLIIENLSSNIALYLTYITHSGTNLTSKFG
VNEVIIHSKAVDFSILILHDTDVTVFGKFCGLLHTNKGNITIVGQVRKSKIISNTGLIKIENNSLNATIP
IVIDSSIIAQYGAVEITGQCSNSYIDSNKVTRKLPNNTSTPPSYLTRLSEIFSALTRTIAR
-
Nucleotide Sequence: 1866 bp     [Download]
>gi|88657561|ref|NC_007799.1|:774594-776459 Ehrlichia chaffeensis str. Arkansas, complete genome
ATGTGTAATAATGCTATGCTAACAAAAGTTCAACAAAGAGCAGCAATAAATAACATAAATTTAAAGCAGT
ATATAAGGGACATCACATTAGAAAAGATTGATGAAGCTCTCATAGATATCAGCAATGTAATACCATTATG
TATAGCACTCATGCTAGATATCACGCCAGATTTTACTTCCTTCAGAAACGAAGTAACATCTATGTTAGAA
GAATATAAGGAATGGTTTATTGCAAACGGGGAAGCAAAAATGCCCCTAATTGATGATAGAACCTCAGACA
CTTTATGGAACAGTATAAAAGAAATACACACATTATACCACAAACACCAAATGTCAATTTCTAGCAACGA
TGGCATTAATATTCTAGATAGAATCGCATTTAACTCTGCTCACAACACGCAAGATATTATAATAGATAAT
AAATTAAAGTATAAAATTCAATATATCATACTGTCATCATTCATTGATCAATGCTTTGATACTGATACTA
ACCCTACAACAATATACAAAACGGAAATTCTACTGCTAACATCTGAAATTAGAAGTAAGATAACGAACAA
ATTAAAAACAACACTATTTCAGTATGTACAAAAAAAAGCTTTTTCCTCATATGCAGAACATTTACGAAAT
TTATATAATATACAAGCATCATATGTAATAGAAAAAAACATTGACTTATTAAGAACAGCCGAACAATTTA
TTGGGTTAAAATCAATTCATATTTTGAACCAAAGAACATTCCGTAAAATCAACCTTTTGCTAGACAGTGG
ATGCGAAATCAATGTTAAATGCGATATTCCAACATACACAGAGATATTTCTAGAAATAAGTGACATAACT
ATCTTCGGCACAGTATACGGCAGCATCTTCAATAAATATGGTAGCATTACTATTATTGATGCAAAAGAAG
AATGTAGCAAAAATATATTATCTATATTCGGAACTGTAAGTATCAATGGAAAAATAATTAAGAACAACTT
ACCTGATATATTTACTATTCCAGCCAATTTCTGCAGAAATATAAAACATAAAACCATAATAACTAGACAA
ACAGATCTCTGCCAAGCAGAAAAAGTAATAACATCATTTCATCCATGTGATGTTATCAATCAAAAAGATC
CAAATGGAATACGTGCATTAAACATAGAACTATTCCACCCTAATTTTCAATACCACACCGTCATTGCATC
CATAGGATGGCCTATCAATAAACAAAACAATACCTCAACTGAAAATGCTGAATTGCTATTTCATAATATA
ATACATAATGCAAACCACTTAAACATAATAGACAACATCAGTAAAAATCAGAGGCTACCAAATACTTTTT
TTAATGATAGCATTCCTATGTTTATTCATAATATACGTATAACAAATAAACAATTAATCATTGAAAATTT
AAGCAGTAATATAGCACTTTACTTAACATACATAACACACAGTGGTACAAATCTTACATCTAAATTTGGT
GTTAATGAAGTAATAATACACAGTAAAGCTGTAGATTTTTCAATTTTAATACTTCATGATACAGATGTAA
CCGTATTTGGTAAATTTTGCGGCTTATTACATACAAACAAAGGTAATATTACAATTGTAGGACAAGTTAG
AAAATCGAAAATTATATCAAACACTGGATTGATTAAAATAGAAAATAACTCTCTTAATGCTACAATTCCA
ATAGTAATAGATAGTTCTATAATCGCACAATATGGTGCAGTAGAAATTACTGGGCAATGCTCCAATTCTT
ATATAGATAGTAATAAAGTAACTAGAAAATTACCAAACAATACCAGTACTCCACCTTCATATCTTACAAG
ACTTTCAGAAATATTTTCTGCACTTACAAGAACAATAGCAAGATAA

Reference
(1) Yan Q et al. (2018). Ehrlichia type IV secretion system effector Etf-2 binds to active RAB5 and delays endosome maturation. Proc Natl Acad Sci U S A. 115(38):E8977-E8986. [PudMed:30181274] experimental
 
experimental experimental literature