| Effector Protein ID: 82700764 |
 T4SS name [ID] | VirB [376] |
| Gene symbol | - |
| Locus tag | BAB1_2005 |
| Strain | Brucella melitensis biovar Abortus 2308 |
| Replicon | chromosome II [GenBank: NC_007618] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 1941656..1942117 [-] |
| Product | cAMP-dependent protein kinase |
| Effector type | Protein |
| Descripton | BPE005 |
| T4CP requirement | T4CP Indepedent |
| Target/Effection | Unknown |
| UniProt ID | Q2YR64 |
| KEGG ID | bmf:BAB1_2005 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | cNMP_binding [PF00027], Evalue: 9.8e-21, Aligned region: 35..122 |
| Protein Sequence: 153 a.a. [Download] |
| >gi|82700764|ref|YP_415338.1| cAMP-dependent protein kinase [Brucella melitensis biovar Abortus 2308] MALDDDIRILGTVGLFESFTPEQLRLLAFGAERLVLRAGRELFREGQSADCAYIIVTGTITLFHEGDEGR VTIRPVGPGAILGEMALIAQTTRLTGAVADVETEVIRISRSIFRRILEEYPEVAAALHAHISRNLVELIG QIEQVAPRLANRD |
| - |
| Nucleotide Sequence: 462 bp [Download] |
| >gi|82698932|ref|NC_007618.1|:c1942117-1941656 Brucella melitensis biovar Abortus 2308 chromosome I, complete sequence ATGGCGCTAGACGACGATATTCGCATTCTCGGCACGGTGGGCCTGTTCGAGTCTTTCACGCCCGAACAGT TGCGCCTGCTTGCCTTCGGTGCGGAGCGGCTTGTCCTGCGTGCGGGACGCGAGCTTTTCCGCGAGGGCCA GAGTGCCGATTGCGCCTATATCATCGTTACCGGCACGATTACCCTGTTTCATGAAGGTGATGAAGGGCGG GTCACGATCCGCCCTGTCGGCCCCGGCGCGATATTGGGGGAAATGGCGCTCATCGCCCAGACCACTCGTC TCACCGGCGCGGTGGCGGATGTGGAAACCGAAGTCATCCGCATCAGCCGCTCCATCTTCCGGCGCATTCT GGAAGAATACCCGGAAGTGGCCGCCGCGCTTCATGCGCATATCAGCCGCAATCTTGTCGAGCTTATCGGC CAGATCGAGCAGGTCGCGCCGCGGCTTGCAAACCGCGACTGA |
| Reference |
| (1) von Bargen K; Gorvel JP; Salcedo SP (2012). Internal affairs: investigating the Brucella intracellular lifestyle. FEMS Microbiol Rev. 36(3):533-62. [PudMed:22373010] |
| (2) de Jong MF; Tsolis RM (2012). Brucellosis and type IV secretion. Future Microbiol. 7(1):47-58. [PudMed:22191446] |
(3) Marchesini MI; Herrmann CK; Salcedo SP; Gorvel JP; Comerci DJ (2011). In search of Brucella abortus type IV secretion substrates: screening and identification of four proteins translocated into host cells through VirB system. Cell Microbiol. 13(8):1261-74. [PudMed:21707904]  
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| experimental literature |
| in silico analysis literature |