| Effector Protein ID: 82700711 |
 T4SS name [ID] | VirB [376] |
| Gene symbol | - |
| Locus tag | BAB1_1948 |
| Strain | Brucella melitensis biovar Abortus 2308 |
| Replicon | chromosome II [GenBank: NC_007618] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 1891813..1893099 [+] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | BspF |
| T4CP requirement | T4CP Indepedent |
| Target/Effection | BspA, BspB and BspF specifically inhibit host protein secretion and membrane trafficking along the secretory pathway. |
| UniProt ID | Q2YLT8 |
| KEGG ID | bmf:BAB1_1948 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | Acetyltransf_6 [PF13480], Evalue: 7.7e-23, Aligned region: 224-366 |
| Protein Sequence: 428 a.a. [Download] |
| >gi|82700711|ref|YP_415285.1| hypothetical protein BAB1_1948 [Brucella melitensis biovar Abortus 2308] MAAKPLLEESAGGNAAHLVSQLSDSSAVIEAAKKMEESLHSRDIPRKLAIYGAAAGFELRDELDHLSNRT IEPNIFFNARFLAPAMPRLEDREVRFMVMRDENETRSRLRFVMPYTVERPGLPLSVPVIRSWATPFGPQG TPLIDHDNPVGVVEDLFDILARRHIKLPEVLVLPEMRANGAAARLIRSVAIGRQLPVQSIEHKERPFLES KLDGKTYIKEAIGAHHRHDYERLWRRLAEQGELVHKVARTPDEVRHAFEHFLTLEARGWKGRRGTAMAVD RFRAAFAREAVNNLAECDCVRIHTLELDGRVIAILIVFTVSGEAWTWKTAYDETFHAWSPGVLLMIEVVK NHLDDPNIARTDSCAVPDHPVMTRLFRERETMETLVVGLHPGADRLVRQAASQIHLYQRTRNLARIIRNR LRSFTEHK |
| - |
| Nucleotide Sequence: 1287 bp [Download] |
| >gi|82698932|ref|NC_007618.1|:1891813-1893099 Brucella melitensis biovar Abortus 2308 chromosome I, complete sequence ATGGCTGCAAAACCTTTGCTTGAGGAATCAGCAGGCGGAAACGCCGCCCATCTTGTTTCGCAACTTTCCG ACAGCAGCGCCGTGATCGAAGCGGCGAAGAAGATGGAGGAAAGCCTGCACAGCCGCGATATTCCGCGCAA GCTTGCCATTTATGGCGCAGCAGCCGGTTTTGAATTGCGTGATGAGCTGGACCATCTGAGCAATCGCACC ATAGAGCCGAACATCTTCTTCAACGCACGTTTTCTGGCGCCTGCCATGCCACGCCTTGAAGACCGTGAAG TTCGCTTCATGGTCATGCGCGACGAAAATGAAACCCGAAGCCGTCTGCGCTTTGTGATGCCCTATACGGT GGAACGCCCCGGCCTGCCACTTTCGGTTCCCGTGATTCGCTCCTGGGCCACCCCCTTCGGCCCGCAGGGC ACGCCGCTCATCGACCATGACAACCCGGTCGGGGTGGTTGAAGACCTGTTCGACATTCTGGCGCGCAGGC ACATCAAGCTGCCCGAAGTACTGGTTTTGCCGGAAATGCGTGCCAATGGAGCAGCCGCCAGGCTGATCCG CTCGGTCGCCATCGGGCGCCAATTGCCGGTTCAATCCATCGAGCACAAGGAACGTCCCTTCCTTGAAAGC AAGCTCGATGGCAAGACCTATATAAAGGAAGCCATCGGGGCGCATCATCGCCATGACTATGAACGATTGT GGCGCCGCCTTGCCGAGCAGGGCGAACTCGTTCACAAGGTTGCCCGCACGCCCGATGAGGTGCGCCATGC CTTTGAACATTTCCTCACACTGGAGGCGCGCGGCTGGAAGGGACGTCGCGGCACAGCCATGGCTGTTGAC CGTTTTCGTGCCGCTTTCGCGCGCGAAGCCGTCAACAATCTTGCCGAATGCGACTGTGTACGCATTCACA CGCTGGAACTTGATGGCAGGGTCATCGCAATCCTCATCGTCTTCACGGTATCAGGCGAAGCCTGGACCTG GAAAACCGCCTATGACGAGACATTTCATGCCTGGTCGCCCGGCGTTCTCCTGATGATCGAAGTGGTGAAG AACCACCTGGACGACCCCAATATCGCCCGCACCGATTCCTGCGCCGTGCCAGACCATCCCGTCATGACGC GCCTCTTCCGTGAACGCGAGACTATGGAAACGCTTGTCGTCGGCCTTCACCCCGGCGCGGATCGGCTGGT GCGGCAGGCGGCATCGCAGATTCACCTCTATCAGCGCACCCGCAATCTCGCGCGCATCATCCGCAACCGG CTGCGCAGTTTCACCGAGCATAAATAA |
| Reference |
(1) Myeni S et al. (2013). Brucella modulates secretory trafficking via multiple type IV secretion effector proteins. PLoS Pathog. 9(8):e1003556. [PudMed:23950720]  
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| experimental literature |
| in silico analysis literature |