SecReT4
Effector Protein ID: 82700286
T4SS name [ID]VirB [376]
Gene symbol-
Locus tagBAB1_1492
StrainBrucella melitensis biovar Abortus 2308
Repliconchromosome II [GenBank: NC_007618] [Browse all T4SS(s) in this replicon]
Location [Strand]1443154..1443726 [-]
Producthypothetical protein
Effector typeProtein
DescriptonSepA
T4CP requirementT4CP Indepedent
Target/EffectionSepA is involved in the initial steps of the intracellular life cycle facilitating certain routes that will ultimately influence the initial composition and final destination of the BCV.
UniProt IDQ2YS16
KEGG IDbmf:BAB1_1492
PDB IDNA
Domain hit(s) vs Pfam NA
Protein Sequence: 190 a.a.     [Download]
>gi|82700286|ref|YP_414860.1| hypothetical protein BAB1_1492 [Brucella melitensis biovar Abortus 2308]
MMPVIRLNDATFADLSVLKTWYGTKTPSETIDRIVREAMEQLDMERDDAAEEVTVTTSDGAMHFDAAPGL
AFTKPLAASIDGKALHSPCWSALLLTMIAQVKTKGLSGDKLVRELAIPAKVERYDEEGFKFRPDLGISVQ
GQSASDCWKEVERLSKKWAIPVSVKFWWKQNPKAQYPGKTGILRSGPASA
-
Nucleotide Sequence: 573 bp     [Download]
>gi|82698932|ref|NC_007618.1|:c1443726-1443154 Brucella melitensis biovar Abortus 2308 chromosome I, complete sequence
ATGATGCCCGTGATTAGACTTAACGACGCCACTTTTGCCGACCTCAGCGTCCTTAAAACCTGGTACGGCA
CGAAGACCCCGAGCGAAACCATTGACCGGATTGTGCGAGAGGCAATGGAGCAGCTTGACATGGAGCGTGA
CGACGCCGCCGAGGAAGTCACCGTAACGACGAGTGACGGCGCGATGCATTTTGATGCCGCGCCCGGGCTG
GCATTCACCAAGCCGCTGGCGGCATCCATCGACGGCAAGGCATTACATAGCCCTTGTTGGTCAGCGCTCT
TATTGACGATGATCGCGCAGGTGAAGACAAAAGGCCTCTCGGGTGACAAGCTCGTTCGCGAACTTGCCAT
CCCTGCAAAGGTTGAGCGGTATGATGAGGAAGGTTTCAAATTCCGTCCTGACCTTGGAATCTCGGTGCAG
GGCCAGTCTGCGTCGGATTGCTGGAAAGAGGTGGAGCGGCTTTCTAAAAAGTGGGCCATCCCGGTGTCGG
TCAAATTCTGGTGGAAGCAGAACCCTAAGGCGCAGTACCCTGGCAAAACTGGCATTTTGCGGTCTGGCCC
GGCGTCCGCCTAA

Reference
(1) Döhmer PH et al. (2014). Identification of a type IV secretion substrate of Brucella abortus that participates in the early stages of intracellular survival. Cell Microbiol. 16(3):396-410. [PudMed:24119283] experimental
 
experimental experimental literature