| Effector Protein ID: 58584293 |
 T4SS name [ID] | VirB [500] |
| Gene symbol | trmE |
| Locus tag | Wbm0032 |
| Strain | Wolbachia endosymbiont strain TRS of Brugia malayi |
| Replicon | chromosome [GenBank: NC_006833] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 41626..42954 [+] |
| Product | tRNA modification GTPase TrmE |
| Effector type | Protein |
| Descripton | wBm0032 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | tRNA modification GTPase |
| UniProt ID | Q5GTQ0 |
| KEGG ID | wbm:Wbm0032 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | MnmE_helical [PF12631], Evalue: 1.3e-54, Aligned region: 123-439 TrmE_N [PF10396], Evalue: 9.5e-36, Aligned region: 7-120 MMR_HSR1 [PF01926], Evalue: 5.2e-18, Aligned region: 219-338 FeoB_N [PF02421], Evalue: 1.6e-07, Aligned region: 218-349 |
| Protein Sequence: 442 a.a. [Download] |
| >gi|58584293|ref|YP_197866.1| tRNA modification GTPase TrmE [Wolbachia endosymbiont strain TRS of Brugia malayi] MMNTDETIFALSTVFGKSGVAVIRISGNHALKALNHFHVNKDMKPRFATLVDLYDSSDQLIDNGIAIYFP APNSFTGEDVIELQVHGGKAVIKIVLEELSRIFVMAKPGEFLLRAFLNGKFDLTQIEGIADLIDAETKMQ AKQAIKQMSGELEKLYSSWRQRLIAVQSKIEAYIDFPEDVATEKNELEKINDEVQTLVQSIQEHLNDNRR GERLREGLHIVITGEPNVGKSTLFNFLARRDIAIVSEYVGTTRDILEAHIDIGGYPIILSDTAGIRESSD PVESEGISRAKKRSCEADLRIELFPFEQRYNINCNVISSNTIYVLSKADDVINDHDIKISDIDFLPVSIL KGIGTEKLVSVIKEKVEEKFVYDRDVPVITRQRHRNCMQKAIEHLRRFNMNNPIELVSEDLRLAASELGV VTGIINVEEVLDDIFNNFCVGK |
| - |
| Nucleotide Sequence: 1329 bp [Download] |
| >gi|58584261|ref|NC_006833.1|:41626-42954 Wolbachia endosymbiont strain TRS of Brugia malayi, complete genome ATGATGAACACGGATGAAACTATTTTTGCCTTATCAACCGTATTTGGTAAGTCAGGAGTTGCAGTAATTA GGATTTCAGGTAATCATGCACTTAAAGCTTTAAATCACTTTCATGTTAATAAAGATATGAAACCAAGGTT TGCTACTTTGGTTGATCTGTATGATAGTTCCGATCAGTTGATTGATAATGGAATAGCAATTTATTTTCCT GCTCCAAACAGCTTCACTGGCGAAGATGTTATAGAATTACAAGTGCACGGAGGAAAAGCAGTCATAAAGA TCGTTTTGGAGGAATTGTCAAGAATCTTTGTCATGGCTAAGCCTGGGGAATTCTTACTTAGGGCTTTTCT GAATGGCAAGTTTGACTTAACGCAGATAGAAGGGATTGCAGATTTAATCGATGCTGAAACAAAGATGCAA GCTAAACAAGCAATTAAGCAGATGTCAGGAGAATTGGAAAAGCTATACAGTAGTTGGAGGCAGAGATTAA TAGCAGTGCAGTCCAAAATTGAAGCATATATAGACTTTCCAGAGGATGTTGCAACAGAAAAAAACGAACT GGAAAAAATCAATGATGAAGTGCAAACTCTTGTGCAGTCAATACAAGAGCATTTGAATGATAATAGGCGG GGCGAAAGATTGCGTGAGGGTTTGCATATTGTAATAACTGGTGAGCCAAATGTTGGTAAATCAACACTAT TTAATTTCTTGGCCAGGCGCGATATTGCTATTGTTTCTGAATATGTAGGCACAACAAGGGACATACTTGA AGCTCATATTGACATTGGCGGATACCCAATCATTCTTTCTGATACTGCTGGAATTCGTGAGAGTTCAGAT CCGGTGGAATCAGAAGGTATAAGTCGAGCAAAAAAGAGGTCTTGTGAAGCTGATTTGAGAATAGAGCTAT TTCCTTTTGAGCAGCGTTATAACATCAATTGCAATGTTATAAGTAGTAACACTATTTACGTGTTGAGCAA AGCTGACGATGTTATCAATGATCACGATATAAAAATTAGCGACATAGATTTTTTACCTGTTTCTATTTTA AAAGGAATAGGCACAGAGAAACTAGTCTCTGTGATTAAAGAAAAAGTAGAGGAAAAATTTGTCTATGATA GAGATGTTCCTGTAATTACCCGGCAAAGGCATAGGAATTGCATGCAGAAAGCTATAGAACATTTACGACG TTTTAATATGAACAATCCAATTGAGTTGGTATCTGAAGACTTAAGGCTTGCCGCATCTGAACTTGGTGTA GTAACCGGGATTATTAATGTTGAAGAAGTATTGGATGATATATTCAATAACTTCTGTGTAGGCAAGTGA |
| Reference |
(1) Carpinone EM et al. (2018). Identification of putative effectors of the Type IV secretion system from the Wolbachia endosymbiont of Brugia malayi. PLoS One. 13(9):e0204736. [PudMed:30261054] 
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| experimental literature |