| Effector Protein ID: 54295621 |
 T4SS name [ID] | Dot/Icm [41] |
| Gene symbol | lepA |
| Locus tag | lpl2708 |
| Strain | Legionella pneumophila str. Lens |
| Replicon | chromosome [GenBank: NC_006369] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 3088528..3091887 [+] |
| Product | effector protein A, substrate of the Dot/Icm secretion system |
| Effector type | Protein |
| Descripton | LepA |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Bacterial egress |
| UniProt ID | Q5WT17 |
| KEGG ID | lpf:lpl2708 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 1119 a.a. [Download] |
| >gi|54295621|ref|YP_128036.1| effector protein A, substrate of the Dot/Icm secretion system [Legionella pneumophila str. Lens] MNEIILHLMNEISTLTPPINPLNLKQIFSSTLLPEGKAPVEVESQLNLLLLIKKYVDEYSSLAEEQEEYK RKKHKLDEVMKKGEELQRKISDLAKKIEHAKNELNPLYKEIEPKANEVLSKQNPLAPPYKFPEYGEVQKS IVVGHYSYLFKTSKEIETTRAKLKLVLLKNKWNALMKDLSQFGIQPPVEEDAVDSLQKFIAAVELEIKKL TRACEKWDELQKRFAKQLSATDINKKETELEKQIELLLKDLGRIETVVTNHSLAPDLKAELTRKFQESED TQGLIQEYQNQIDGLLSNFNPSSWLSWYSDSNYSDNQQKLKNSVSFLQLLAQQRELKTKHHELVKQQELL IKAIPETPSNEEDLSIYKKLVPDAIDLINEIPIESIPNFVLPSGLSYDSSPADFYLVLLILMPKVSEKKE QFSQALEKLQEMPALGKQIQQLRSGYDLPITMDVQLPSLQEAEESKDSLNTEDPLKEELKSQIKLCQSYL ETARQIDSLMKDHGQTTNEAKALIEQLRLISNQPLKNEDINSIKEDLSTLANQIQSLVSELNQLPLPNMS GEKIDPPLEKQEIAVDKAIPLAVESMHPAQVIQTGNDSPIEKQQLDNEEETPVVLDSTCTPQAIHKELES TTEKLQVDNGHEIPVVLESTRSPQIIHTESESVGKKQHVEVEQEIPVALELIRPSSIVEKDSVATVEKQQ VTERQETPIVLESTRLSPMVQKDSGLSGEKQHKEIEQEISVVPELTLRTQVVQQSSESSLEQQVPNGQET LAVVKSSPSEPLRPSTPEVPAISRKPNGLSLFNGHDELSEDNILAFFDEAGNQISISSEEDSETFTIDKG KVISSGIDKAFKEKPVSTGHESDKLSNPQHKESAPSISPLPPSSILLKQKLDSFHVQNMEYIKQHSEEIQ LWYKGLYDAAQSSCVNEALGLKALHLLKDILFELKKQNDLSVLLAYKRMCPNPLQDIQNILRLKPALPIL DESIDEEQQLKNWPEELHKFHQQYVKLKKEHPLEAELFIQAIHSLISIKHLVELPDAKTSNREAMPLITQ DPRYEPLKRHRGFIRAWEYIEDFFRMLIGKLTGQDEYEYSKRPCFFKTRSHRLLEEVDTMLHPMAPTSS |
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| Nucleotide Sequence: 3360 bp [Download] |
| >gi|54292964|ref|NC_006369.1|:3088528-3091887 Legionella pneumophila str. Lens, complete genome ATGAACGAAATCATACTGCACTTAATGAATGAAATCTCCACCTTGACTCCACCAATTAACCCCTTAAATT TAAAGCAGATATTTAGTTCAACCCTACTGCCGGAAGGAAAAGCTCCTGTTGAAGTTGAATCCCAATTAAA TCTTTTATTGTTAATTAAAAAATATGTTGATGAATATTCCAGTTTAGCTGAAGAACAAGAAGAGTATAAA AGGAAAAAACACAAATTAGATGAGGTCATGAAAAAAGGAGAAGAACTGCAAAGAAAAATTTCTGATTTGG CTAAAAAAATTGAGCACGCAAAAAATGAATTAAATCCTTTATACAAAGAAATCGAACCCAAAGCGAATGA AGTCCTGTCCAAACAAAACCCATTAGCGCCTCCTTATAAATTCCCTGAATACGGAGAGGTTCAAAAATCA ATTGTAGTCGGGCACTACAGTTATCTCTTCAAAACCAGTAAGGAAATAGAAACTACACGTGCCAAATTAA AGCTGGTTTTGCTGAAAAATAAATGGAATGCCTTAATGAAAGATTTGTCTCAGTTCGGCATTCAACCTCC TGTGGAAGAAGATGCTGTTGATAGTTTACAAAAATTTATAGCTGCAGTTGAATTGGAAATTAAAAAATTA ACTCGCGCTTGTGAAAAATGGGATGAATTGCAAAAGCGATTCGCCAAACAATTATCTGCAACTGATATTA ATAAAAAAGAGACTGAGCTAGAAAAACAAATTGAACTATTGCTTAAAGACCTGGGTCGTATTGAAACCGT AGTAACTAACCACTCCCTGGCACCCGATTTAAAAGCAGAGTTAACCAGGAAATTTCAAGAAAGTGAAGAC ACTCAAGGATTGATACAAGAATACCAAAACCAGATTGATGGATTATTATCTAATTTTAACCCATCTTCCT GGCTTTCATGGTATTCGGATTCTAATTATTCTGATAATCAGCAAAAACTTAAGAATTCAGTTAGCTTCCT GCAATTATTAGCTCAACAAAGAGAGCTAAAAACCAAACATCATGAACTTGTGAAACAGCAAGAACTGTTG ATTAAAGCGATACCAGAAACTCCTTCAAATGAAGAGGATTTATCTATTTATAAAAAATTAGTTCCTGATG CCATTGACCTGATAAATGAAATACCAATAGAAAGTATACCAAATTTTGTTTTACCAAGTGGCCTTTCTTA TGACTCTTCGCCGGCCGATTTTTATTTGGTACTTCTCATTCTCATGCCAAAAGTTTCAGAAAAGAAGGAA CAATTTTCACAAGCGTTGGAAAAACTTCAAGAAATGCCTGCTCTGGGCAAACAAATACAACAACTAAGAA GTGGATACGATTTACCTATAACTATGGATGTACAACTTCCAAGTTTGCAAGAAGCTGAAGAAAGTAAAGA TTCATTGAATACAGAGGATCCTCTTAAAGAAGAGTTAAAAAGCCAGATTAAACTATGCCAATCTTATCTT GAAACAGCCAGGCAAATTGATTCGCTTATGAAAGATCATGGACAAACAACCAATGAAGCAAAAGCACTTA TTGAGCAATTGCGTTTAATTTCAAATCAACCACTAAAGAACGAAGACATAAACTCTATTAAAGAAGATTT ATCTACTCTTGCCAATCAAATCCAATCCCTAGTGTCTGAATTAAATCAATTACCTTTGCCTAATATGTCC GGTGAAAAAATTGATCCTCCATTGGAAAAACAGGAAATAGCAGTAGATAAAGCAATCCCTCTTGCTGTGG AATCGATGCACCCTGCCCAAGTAATTCAGACAGGCAATGATTCTCCCATAGAAAAACAGCAGCTAGACAA TGAGGAAGAAACGCCGGTTGTTCTGGATTCAACATGCACTCCTCAAGCCATTCATAAGGAACTTGAATCT ACCACTGAAAAACTGCAAGTAGACAATGGACACGAAATACCGGTTGTTCTCGAGTCAACACGTTCTCCTC AAATCATTCATACTGAGTCTGAATCTGTTGGTAAAAAGCAGCATGTAGAAGTAGAGCAAGAGATACCGGT CGCACTGGAATTAATACGACCCTCATCTATAGTTGAAAAGGATTCCGTAGCTACTGTAGAAAAACAGCAA GTAACTGAGAGACAAGAAACACCAATCGTCCTTGAATCAACACGACTCTCTCCTATGGTTCAGAAAGACA GTGGGCTTTCTGGCGAAAAGCAACATAAAGAGATAGAGCAAGAAATATCTGTCGTTCCGGAATTAACACT CCGCACCCAAGTGGTTCAGCAAAGCTCTGAGTCCAGTTTAGAACAACAAGTACCCAACGGACAAGAAACA CTGGCTGTTGTCAAATCAAGCCCATCGGAACCATTGAGACCATCAACCCCTGAGGTTCCAGCTATATCCA GGAAACCAAATGGCTTGTCATTATTTAATGGTCACGATGAATTATCAGAAGATAATATTTTAGCCTTTTT TGATGAGGCTGGTAATCAAATTAGCATCTCATCTGAAGAAGATTCTGAGACGTTTACCATAGACAAGGGA AAAGTAATTTCCTCAGGAATTGATAAAGCATTTAAAGAAAAGCCTGTTTCTACAGGCCATGAGTCAGATA AATTATCAAATCCTCAACACAAGGAATCTGCCCCTAGCATCTCCCCTTTACCACCATCTTCTATCCTGCT TAAGCAAAAATTAGATTCATTTCATGTACAAAACATGGAATATATAAAGCAACATTCAGAAGAAATACAG CTATGGTATAAAGGTTTATATGATGCAGCGCAAAGTTCATGTGTAAATGAGGCATTGGGGCTTAAAGCAC TTCATCTTTTAAAGGACATCTTGTTTGAATTAAAAAAGCAAAATGATTTATCTGTATTACTGGCTTACAA GCGCATGTGCCCAAACCCATTGCAAGATATACAAAATATTCTCCGCTTAAAACCTGCTCTGCCTATACTT GATGAATCGATTGATGAAGAACAGCAGTTAAAGAATTGGCCTGAAGAATTGCACAAATTTCATCAGCAAT ATGTAAAATTAAAAAAGGAACATCCATTGGAAGCTGAATTATTTATTCAGGCAATCCATTCACTTATTTC AATTAAACATTTGGTGGAACTTCCTGATGCAAAAACTTCAAACCGAGAGGCCATGCCTCTCATTACTCAA GATCCCCGATATGAGCCTTTAAAACGGCATAGGGGATTTATAAGAGCATGGGAATATATTGAAGATTTTT TCCGAATGTTAATAGGTAAGTTAACAGGGCAAGATGAATATGAGTATTCAAAAAGGCCTTGTTTTTTCAA AACAAGATCTCACCGATTACTTGAAGAGGTTGACACAATGCTCCACCCCATGGCTCCAACAAGTAGTTAA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| in silico analysis literature |