SecReT4
Effector Protein ID: 54295421
T4SS name [ID]Dot/Icm [41]
Gene symbolsidF
Locus taglpl2507
StrainLegionella pneumophila str. Lens
Repliconchromosome [GenBank: NC_006369] [Browse all T4SS(s) in this replicon]
Location [Strand]2857821..2860559 [+]
Productsubstrate of the Dot/Icm system
Effector typeProtein
DescriptonSidF
T4CP requirementT4CP Depedent
Target/EffectionAntiapoptosis
UniProt IDQ5WTL7
KEGG IDlpf:lpl2507
PDB IDNA
Domain hit(s) vs Pfam NA
Protein Sequence: 912 a.a.     [Download]
>gi|54295421|ref|YP_127836.1| substrate of the Dot/Icm system [Legionella pneumophila str. Lens]
MPRITENIETYVTHLLSDLEPVPSQNQHLAYGYPGERQVFKDPILDGKQVVVVNSQYDKHGRPVTGQPDV
IQEANNYIDNLVAAAKSLIDKDKKGEKDLRKNAIDEMAKTFKKSISETIPSDKAKADLFSSKKSSANKDF
LEQLAKVEGSLQQFTQAVAKASGHKLKALDKEGHNIRSHNRDTLIHRFKAPNSKEGEEQFIMYIPCGRYT
KRQQRLMGKDESEVNRDHDTTSHKRSDLVLGNSSMARMIVGTRHSDGTVTIHHDSFSGPGARMPYSDFKG
ADDYKKLAIKAVTLINQEEVIQTLAQRQIDRMTNEDLWNKIPEEYRPDELPPDAEKARAQLIKLYVEHNP
LSVTECYTQVVTAGQRVAAENQKEQFEYVRQMMDAFDGSKAKITIQTGSNTEVETEVGYQARMSSWGVNW
FRQVGALNPFSDNSVTKNQNARFVNQMTDDVISNLGKVAQNLGDYDKAGALHTLLKGPNVSDLNQQITEK
ENALKEVKGAYREALFSYFEEYQKGEGKWDQAKLDQLKNQVDGYEKSIKKQESAIYELHNQIDALRKAYY
TEHKGQINKALQELKEQISPVIQNKETDPETKSRLQHFYNSCAYLMQAQELYYENTWHHGKNNFKLQTLM
ASLSCELDYANTKGCKSNNDRGQRLAQKIVGNALWTAMSEDGLFTGEFLDHRRTHGKEVSKVEQLDRELT
TIQALHHTANTGVSGGKFEIQDKTNFADNGLFGKVANFAKVKEMGPENAFTKNMGTKIKAGLGLGLLAAA
GLVALTLLFPPAGLAVAALGIGVAAGAAIVAGVTFAATYLFGTAIDAINNKIEEGKIKSIVREGMKAASE
NSPQHKTEQKDHLTVNAKLHQQLGVTRESVLERQSTPKQEFEKPKDMTSKVDLTPAMEDDKRSESTPTPV
NF
-
Nucleotide Sequence: 2739 bp     [Download]
>gi|54292964|ref|NC_006369.1|:2857821-2860559 Legionella pneumophila str. Lens, complete genome
ATGCCACGAATCACTGAAAATATAGAAACCTATGTCACGCATTTATTAAGTGATCTGGAACCCGTTCCTT
CTCAAAATCAGCATCTTGCCTACGGTTATCCTGGCGAAAGACAGGTATTCAAAGACCCGATACTGGATGG
GAAACAAGTCGTGGTAGTGAACAGTCAATATGATAAACATGGCAGACCTGTTACAGGGCAGCCTGATGTG
ATCCAAGAGGCGAATAATTATATAGACAATCTTGTAGCCGCTGCCAAATCTCTGATAGACAAAGATAAGA
AAGGTGAGAAAGATTTGAGAAAAAATGCCATTGATGAAATGGCAAAAACTTTCAAAAAGTCCATTTCAGA
AACCATTCCTTCCGACAAAGCAAAAGCGGATTTGTTTTCAAGTAAAAAAAGCTCTGCCAATAAAGACTTT
CTGGAACAGTTGGCCAAAGTCGAAGGCAGTTTACAGCAATTCACACAGGCTGTCGCAAAAGCCTCAGGTC
ATAAATTAAAAGCACTGGATAAAGAAGGACATAATATTCGCAGTCATAATCGCGATACCTTGATACATCG
CTTTAAAGCGCCCAACTCTAAAGAAGGCGAAGAACAATTTATTATGTACATTCCGTGTGGAAGGTACACC
AAACGCCAACAAAGGCTAATGGGCAAGGATGAATCTGAAGTCAACAGAGATCACGATACTACAAGTCATA
AACGTTCTGACCTGGTTCTGGGCAACAGCAGTATGGCGCGCATGATTGTCGGGACAAGGCATTCTGATGG
CACCGTGACTATTCACCATGACAGTTTTTCTGGTCCTGGTGCACGCATGCCCTATTCTGATTTTAAGGGT
GCTGATGACTATAAAAAGCTGGCTATCAAAGCGGTCACCTTAATTAACCAGGAAGAGGTCATCCAAACCC
TGGCACAGCGTCAAATTGACCGAATGACCAATGAAGACCTTTGGAATAAAATTCCTGAAGAGTACCGCCC
TGATGAACTTCCCCCTGATGCAGAGAAAGCACGGGCGCAATTAATAAAGCTGTATGTAGAACATAATCCA
TTATCTGTCACGGAATGTTATACACAAGTTGTAACAGCCGGGCAAAGGGTAGCGGCCGAAAATCAAAAAG
AACAATTTGAATACGTGCGGCAAATGATGGATGCTTTTGATGGCTCCAAAGCAAAAATCACCATTCAAAC
CGGCTCCAATACAGAAGTGGAAACAGAGGTTGGTTATCAGGCGCGTATGAGTTCCTGGGGAGTGAATTGG
TTTAGACAGGTTGGAGCGCTCAATCCGTTCTCTGACAATAGTGTCACAAAAAATCAAAATGCGCGTTTTG
TAAATCAAATGACTGATGACGTCATTAGCAATTTAGGCAAAGTGGCACAAAACCTGGGTGATTATGACAA
AGCAGGCGCATTACACACGTTATTAAAAGGCCCAAATGTCAGCGACCTTAATCAACAAATCACTGAGAAA
GAAAATGCCTTAAAAGAGGTAAAAGGAGCCTATCGAGAAGCATTATTCAGCTATTTTGAAGAATATCAGA
AAGGCGAAGGGAAATGGGATCAAGCCAAACTGGATCAATTGAAAAATCAGGTTGATGGCTATGAAAAAAG
CATTAAAAAACAAGAATCAGCCATTTATGAACTGCATAATCAAATCGATGCCTTAAGAAAGGCTTATTAC
ACAGAACACAAAGGGCAAATCAATAAGGCTTTACAAGAACTTAAAGAACAAATAAGCCCTGTAATCCAGA
ATAAAGAAACAGATCCGGAAACCAAATCCAGACTGCAACACTTTTACAATTCATGTGCTTACCTCATGCA
AGCTCAAGAGCTCTATTATGAGAACACCTGGCATCATGGCAAAAATAATTTCAAGCTGCAAACCTTAATG
GCTTCTCTCTCCTGCGAGCTGGATTACGCCAATACGAAAGGATGTAAGAGTAATAATGATCGTGGCCAAA
GATTAGCGCAAAAAATTGTTGGGAATGCTTTATGGACAGCAATGAGTGAGGACGGGTTATTCACTGGTGA
ATTTCTGGATCATCGACGGACACATGGTAAAGAAGTTAGTAAAGTAGAACAACTTGATCGGGAACTTACT
ACTATACAGGCCCTTCATCATACTGCCAATACGGGTGTTTCCGGCGGAAAGTTTGAAATTCAGGATAAGA
CCAACTTTGCTGATAATGGCCTTTTCGGTAAGGTCGCTAATTTTGCCAAAGTAAAAGAAATGGGGCCTGA
AAACGCTTTTACCAAAAATATGGGTACAAAAATTAAAGCAGGTCTCGGGCTTGGGTTACTAGCGGCTGCT
GGATTAGTCGCCCTTACTTTGCTATTCCCTCCGGCAGGCTTGGCTGTGGCCGCCTTGGGAATTGGTGTGG
CAGCCGGTGCCGCCATTGTTGCTGGCGTTACTTTTGCGGCCACTTATCTTTTTGGTACCGCTATTGATGC
CATTAATAACAAGATAGAAGAAGGAAAGATTAAATCCATTGTTCGCGAGGGTATGAAAGCGGCATCAGAA
AATTCACCACAACACAAAACCGAACAAAAGGATCATTTAACGGTGAATGCCAAACTTCATCAACAATTAG
GTGTGACGCGAGAGTCTGTCTTGGAAAGACAATCCACTCCAAAACAAGAGTTTGAAAAACCCAAAGATAT
GACCTCGAAAGTTGACTTAACACCAGCGATGGAGGATGATAAGCGAAGCGAAAGCACCCCCACGCCAGTA
AACTTCTAA

Reference
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] in_silico
 
in_silico in silico analysis literature