| Effector Protein ID: 54295362 |
 T4SS name [ID] | Dot/Icm [41] |
| Gene symbol | - |
| Locus tag | lpl2447 |
| Strain | Legionella pneumophila str. Lens |
| Replicon | chromosome [GenBank: NC_006369] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2788074..2789693 [-] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | LnaB |
| T4CP requirement | T4CP Depedent |
| Target/Effection | LnaB is a activator of NF-kappaB (Losick, et al. 2010) |
| UniProt ID | Q5WTS6 |
| KEGG ID | lpf:lpl2447 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 539 a.a. [Download] |
| >gi|54295362|ref|YP_127777.1| hypothetical protein lpl2447 [Legionella pneumophila str. Lens] MSYQKIELSISLSLDSPKLDESDFILLSVKYLEKSLGKKKEFSGFFEDIEKLYFKQNYKEAIEKILDFSK KNESLLSEQVVQRLAEVAPRLKSNPKDNESRRLYETLYADHLESVIKQESDLSVFNELRDSYNAVKPEYA VTHETEIKTLDEAKQFILSFVMLNDNVELPLKAQSERYPKKDRSREELGNTPSANPGIMKPNSPNFTDNL VPVRDVPKIAINEKVAGGYSKTKPTTPFVASLSGTTYSLMVVLTDYIEKHKTDKDIEKKVNQIINLWISS YIKEGYHSYSEVVDVLTEPFLQSIFDKANIKLNYGVLEDTHAEFRKAQDYVFGLTIRSAMHHELQERFKN KEKLQEEVKNFESGLNKLNQNVENTGRHREVLNKLNEVFQDWSAGKKSYDAFKGESNQLIYDIESEEQKS NRGLGSMLKNLGNYLLHLITLRFLKEDYPKPSSPVTMLVTELRGTLEQIDHFHKTSLSLKKATQPDPKNT SPSGETTDVLKSAVDTDKHDKNQESEVIKILDSEQLEEERQDDKIARLQ |
| - |
| Nucleotide Sequence: 1620 bp [Download] |
| >gi|54292964|ref|NC_006369.1|:c2789693-2788074 Legionella pneumophila str. Lens, complete genome ATGTCATACCAAAAAATAGAACTCAGTATTTCATTATCATTAGATTCTCCAAAATTAGATGAGTCTGATT TTATATTGCTCTCAGTTAAGTATCTTGAAAAGTCACTTGGCAAAAAGAAAGAGTTTTCTGGTTTTTTTGA AGACATAGAAAAGCTCTATTTTAAGCAGAATTACAAGGAAGCAATTGAAAAAATATTGGATTTCTCTAAA AAAAATGAATCCTTGTTAAGTGAACAAGTTGTCCAGAGGCTGGCAGAGGTCGCTCCCAGATTAAAAAGCA ATCCTAAAGACAATGAAAGCAGAAGGCTTTATGAAACCTTGTATGCAGATCACCTTGAATCAGTCATTAA ACAAGAGAGTGATCTTTCCGTATTTAACGAATTGAGAGACAGTTATAATGCGGTGAAACCTGAGTATGCA GTAACTCATGAGACCGAAATCAAAACTTTGGATGAAGCAAAGCAATTTATTTTATCTTTTGTCATGCTGA ATGATAATGTTGAATTACCTTTAAAAGCACAATCAGAGAGATACCCAAAAAAGGACAGATCCAGAGAAGA ATTGGGGAATACTCCATCTGCGAATCCAGGTATTATGAAACCTAACTCACCTAATTTTACCGATAATCTG GTGCCTGTCAGAGATGTGCCCAAAATAGCCATTAATGAGAAAGTGGCGGGTGGGTATTCAAAAACCAAGC CTACTACTCCTTTTGTGGCGTCGCTGTCTGGCACAACCTACTCACTTATGGTGGTGTTAACAGACTATAT TGAAAAGCATAAAACAGATAAAGACATTGAAAAAAAAGTAAACCAGATTATTAATTTATGGATTTCCAGT TATATCAAAGAAGGTTATCACAGCTACAGTGAGGTTGTGGATGTTTTAACAGAGCCCTTTCTTCAATCTA TTTTTGATAAAGCAAATATTAAATTAAATTATGGTGTACTTGAAGACACGCATGCAGAATTTCGTAAAGC TCAGGATTATGTTTTTGGTTTGACAATTCGATCAGCAATGCATCATGAGTTACAAGAGCGATTTAAGAAT AAAGAAAAACTGCAGGAAGAGGTAAAGAATTTTGAATCTGGGTTAAATAAACTCAACCAGAATGTCGAAA ATACAGGTCGCCATCGCGAGGTACTGAATAAATTAAACGAGGTATTTCAGGATTGGTCTGCGGGCAAAAA AAGCTATGATGCTTTTAAAGGTGAGTCTAATCAACTGATTTATGATATTGAGTCTGAAGAACAGAAAAGT AATCGTGGTCTTGGCTCCATGCTGAAGAACCTCGGGAACTATCTTTTACACTTGATTACCCTTCGTTTTT TGAAAGAAGACTATCCAAAACCGTCTAGTCCGGTCACAATGTTAGTCACTGAATTAAGAGGCACACTTGA GCAAATAGATCATTTTCATAAAACCAGCCTCTCTTTAAAAAAAGCAACGCAGCCTGACCCTAAAAATACT TCGCCATCTGGTGAGACAACAGATGTTCTGAAATCAGCTGTCGATACTGATAAGCATGATAAAAACCAGG AAAGTGAAGTAATAAAGATATTAGACTCTGAGCAACTGGAGGAAGAAAGGCAAGATGACAAAATAGCTCG TTTACAATAG |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
|
| in silico analysis literature |