| Effector Protein ID: 54295348 |
 T4SS name [ID] | Dot/Icm [41] |
| Gene symbol | sidC |
| Locus tag | lpl2433 |
| Strain | Legionella pneumophila str. Lens |
| Replicon | chromosome [GenBank: NC_006369] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2770729..2773455 [+] |
| Product | SidC protein (substrate of the Dot/Icm system) |
| Effector type | Protein |
| Descripton | SidC |
| T4CP requirement | T4CP Depedent |
| Target/Effection | SidC recruits endoplasmic reticulum vesicles to a replication-permissive vacuole. (Ragaz et al, 2008) |
| UniProt ID | Q5WTU0 |
| KEGG ID | lpf:lpl2433 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 908 a.a. [Download] |
| >gi|54295348|ref|YP_127763.1| SidC protein (substrate of the Dot/Icm system) [Legionella pneumophila str. Lens] MVINMVDVIKFKEPERCDYLYIDENNKVHILLPIVGGDEIGLDNTCQTAVELITFFYGSAHSGVTKYSAE HQLSEYKRQLEEDIKAINSQKKISPHAYDDLLKEKIERLQQIEKYIELIQVLKKQYDEKNDIRQLRTGGI PQLPSGVKEIIKSSENAFAVRLSPYDNDKFTRFDDPLFNVKRNISKYDTPSRQAPIPIYEGLGYRLRSTL FPEDKTPTPINKKSSKEKIVETVLAQVDADYMKDGDKEQKLEELKKLIQQELVKIDSNLSVNMSRDGKEV NLSYLDIVMALDDDSTIKDWIEGIIEVSIDPTVWEAQASSPFYDGAKEIKSDHEADRISIRVQYLLAEAN IYCKTNKLSDANFGEFFDKEPHATEIAKRVKEGFTQGAEIEPIIYDYINSNHAELGLKSPLTSEQQQEIT EKFTRHYNTIKESPHFDEFFVADPDKKGNIFSHQGRISCHFLDFFTRQTKGKHPLGDLASHQEALQEGTS NRLHHKNEVVAQGYEKLDQFKKEVVKLLAENKPKELLDYLVATSPTGVPNYSMLSKETQNYIAYNRNWPA IQKELEKATSIPESQKQDLSRLLSRDNLQHDNLSAITWSKYSSKPLLDVELNKIAEGLELTAKIYNEKRG REWWFKGSRNEARKTQCEELQRVSKEINTLLQSESLTKSQVLEKVLNSIETLDKIDRDISAESNWFQSTL QKEVRLFRDQLKDICQLDKYAFKSTKLDEIISLEMEEQFQKIQDPAVQQIVRDLPSHCHNDEAIEFFKTL NPEEAAKVASYLSLEYREINKSTDKKTLLEQDIPRLFKEVNTQLLSKLKEEKAIDEQFHEKLSQLADKIA PEHFTRNNIIKWSTNPEKLEESNLSEPIKSVQPPTTKQTSIQFREAMGEITGRNEPPTDTLYTGVIKK |
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| Nucleotide Sequence: 2727 bp [Download] |
| >gi|54292964|ref|NC_006369.1|:2770729-2773455 Legionella pneumophila str. Lens, complete genome ATGGTGATAAACATGGTTGACGTAATCAAATTCAAAGAGCCGGAACGTTGTGACTACCTATATATTGATG AAAACAACAAAGTTCATATCCTTTTACCGATTGTAGGAGGAGATGAGATAGGTCTGGATAACACCTGCCA AACAGCAGTTGAGTTGATTACATTTTTCTATGGTAGCGCGCACAGTGGTGTGACCAAATATTCTGCTGAA CACCAACTTAGTGAATACAAAAGGCAATTGGAAGAAGACATCAAAGCCATTAATAGCCAAAAGAAAATTT CACCTCATGCTTATGACGATTTATTAAAAGAGAAAATAGAACGCTTACAGCAAATTGAAAAATACATTGA ATTAATTCAAGTACTAAAAAAACAATATGATGAAAAAAATGATATCAGGCAACTACGTACTGGAGGGATT CCACAATTACCTTCTGGAGTAAAGGAAATCATTAAATCATCTGAAAATGCCTTTGCTGTGAGACTTTCTC CTTATGACAACGACAAATTTACTCGCTTTGATGACCCTTTATTCAATGTCAAAAGAAACATCTCTAAATA CGATACACCCTCAAGGCAAGCTCCTATTCCAATATACGAGGGATTAGGGTATCGCCTGCGTTCAACTCTG TTCCCGGAAGATAAAACACCAACTCCAATCAATAAAAAATCATCTAAGGAAAAAATAGTAGAAACCGTAC TGGCACAAGTAGATGCGGACTATATGAAAGATGGAGACAAGGAACAAAAACTGGAAGAGTTAAAAAAACT GATTCAACAAGAGCTGGTAAAAATTGACTCCAATCTGTCAGTAAACATGAGTCGCGATGGTAAAGAAGTC AACCTGAGCTATTTGGATATCGTCATGGCTTTAGACGATGATTCCACTATTAAAGATTGGATTGAAGGGA TTATTGAAGTATCAATAGATCCTACTGTATGGGAAGCTCAGGCATCCAGCCCTTTCTATGATGGCGCTAA AGAAATAAAATCAGACCACGAAGCAGACAGGATATCCATCAGAGTTCAGTACCTGTTGGCCGAAGCAAAC ATTTATTGTAAAACAAACAAATTATCGGACGCTAACTTCGGAGAATTTTTCGACAAAGAGCCTCATGCTA CTGAAATTGCGAAAAGAGTAAAAGAAGGATTTACGCAAGGTGCAGAGATAGAACCAATTATATACGACTA TATTAACAGCAACCATGCCGAATTAGGATTAAAATCTCCGTTAACAAGCGAGCAACAACAAGAAATCACA GAAAAATTTACAAGACATTATAATACAATTAAGGAATCTCCTCATTTCGATGAGTTTTTTGTCGCTGATC CCGATAAAAAAGGCAATATCTTTTCTCATCAAGGCAGAATCAGTTGTCATTTTCTGGATTTCTTTACTCG ACAAACCAAAGGCAAACATCCTCTTGGTGATCTTGCAAGTCATCAGGAAGCTCTCCAGGAAGGAACCTCC AATCGCTTACATCACAAGAATGAGGTAGTAGCCCAGGGGTACGAAAAACTGGATCAATTCAAGAAAGAGG TTGTCAAACTGCTGGCTGAGAATAAACCAAAAGAATTATTGGATTATTTGGTTGCTACCTCACCTACAGG TGTTCCAAATTACTCCATGCTTTCGAAGGAAACTCAAAATTACATTGCTTACAATCGTAACTGGCCAGCC ATTCAAAAAGAGCTGGAAAAGGCTACCAGCATCCCGGAGAGTCAAAAACAAGATCTTTCAAGATTGCTTT CTCGTGATAATTTACAACACGATAATCTAAGCGCAATTACCTGGTCAAAATATTCCTCCAAGCCATTATT GGATGTTGAATTAAATAAAATCGCTGAAGGATTAGAACTCACTGCAAAAATTTACAACGAAAAGAGAGGA CGCGAATGGTGGTTTAAAGGTTCAAGAAATGAAGCTCGTAAGACCCAATGTGAAGAATTGCAAAGAGTAT CCAAAGAAATCAATACTCTTCTGCAAAGTGAATCTTTAACGAAAAGCCAGGTTCTTGAAAAGGTTTTAAA CTCTATTGAAACATTAGATAAAATTGACAGAGACATTTCTGCCGAATCCAATTGGTTTCAAAGTACTCTG CAAAAGGAAGTCAGGTTATTTCGAGATCAATTGAAAGATATTTGCCAATTGGACAAGTATGCCTTTAAAT CAACAAAACTTGATGAAATCATCTCTCTGGAAATGGAAGAACAATTTCAAAAGATACAAGATCCTGCTGT TCAACAAATTGTCAGGGACTTGCCTTCTCATTGTCACAATGATGAAGCAATTGAATTCTTTAAGACATTG AACCCTGAAGAGGCAGCAAAAGTAGCTAGCTATTTAAGCCTGGAATACAGGGAAATTAATAAATCAACCG ATAAGAAAACTCTCCTGGAACAAGATATTCCCAGACTGTTTAAAGAGGTCAATACGCAGTTACTCTCCAA ACTAAAAGAAGAAAAAGCGATTGATGAGCAATTTCATGAAAAACTCAGTCAACTGGCTGACAAAATTGCC CCCGAGCATTTTACAAGAAATAACATTATAAAATGGTCTACTAACCCTGAAAAGCTTGAGGAATCAAATC TTAGTGAGCCAATCAAATCAGTCCAACCCCCTACTACTAAACAAACATCAATACAATTCAGGGAAGCGAT GGGTGAAATCACTGGAAGAAATGAGCCTCCTACAGACACTTTGTACACGGGAGTTATAAAGAAATAG |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| in silico analysis literature |