| Effector Protein ID: 54295347 |
 T4SS name [ID] | Dot/Icm [41] |
| Gene symbol | sdcA |
| Locus tag | lpl2432 |
| Strain | Legionella pneumophila str. Lens |
| Replicon | chromosome [GenBank: NC_006369] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2767861..2770578 [+] |
| Product | SdcA protein, paralog of SidC (substrate of the Dot/Icm system) |
| Effector type | Protein |
| Descripton | SdcA |
| T4CP requirement | T4CP Depedent |
| Target/Effection | A paralog of sidC which is important for Legionella-containing vacuole recruitment of endoplasmic reticulum -derived vesicles |
| UniProt ID | Q5WTU1 |
| KEGG ID | lpf:lpl2432 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 905 a.a. [Download] |
| >gi|54295347|ref|YP_127762.1| SdcA protein, paralog of SidC (substrate of the Dot/Icm system) [Legionella pneumophila str. Lens] MVDKIKFKEPERCEYLHIDKDNKVHILLPIVGGDEIGLDNTCETTGELLAFFYGKTHGGTKYSAEHHLNE YKKNLEDDIKAIGVQRKISPNAYEDLLKEKKERLEQIEKYIDLIKVLKEKFDEQREIDKLRTEGIPQLPS GVKEVIQSSENAFALRLSPDRPDSFTRFDNPLFSLKRNRSQYEAGGYQRATDGLGARLRSELLPPDKDTP IVFNKKSLKDKIVDSVLAQLDKDFNTKDGDRNQKFEDIKKLVLEEYKKIDSELQVDEDTYHQPLNLDYLE NIACTLDDNSTAKDWVYGIIGATTEADYWPKKESESGTEKVSVFYEKQKEIKFESDTNTMSIKVQYLLAE INFYCKTNKLSDANFGEFFDKEPHATEVAKRVKEGLVQGAEIEPIIYNYINSHYAELGLTSQLSSKQQEE ITEKFTQRYHIIENSPHFDEFFVADPDKKGNIFSHQGRMSCHFLDFFARQTKGKHPLGDLAGHQEALQAG TSNRLHHKNEVVAQGYEKLDQFKKEVVKLLAESKPKELLDYLVATSPTGAPNYSMLSKETQNYIAYNRNW PAIQTELEKTTDIPENQKQDLVRLLSRNNLQHENLSAITWSKYSSKPLLDVELNKIAEGLDLTAKIYNEK RKSEWFKGSRNEARKTQCEELQRVSQEINALLQSESLTKSQVLEKVLNSIEALDKIDRDISAEYNLFKST LQKEVQSFREQLKDICQLDNYAFKSTKLDEIISLEMEEQFQMIKDPAVQQIVRDLPSHCHNNEVIEFFMT LNPEEAAKVASYLSLEYREINKSTDKAKLLNEDIPNLFKEVNMQLLSKLKEDSVLGEGVYEKLAQLADKI PPEHFTRNNIRKWSANPEKLEESNLGELLKSSDSSLSEMARKYRETINEMTGRNEPPRETVRHTI |
| - |
| Nucleotide Sequence: 2718 bp [Download] |
| >gi|54292964|ref|NC_006369.1|:2767861-2770578 Legionella pneumophila str. Lens, complete genome ATGGTTGACAAAATAAAATTCAAAGAGCCGGAGCGATGCGAATATTTACATATCGATAAGGATAATAAAG TCCATATTCTTTTACCTATTGTAGGTGGGGATGAAATAGGACTGGATAATACCTGTGAAACAACAGGTGA GTTATTAGCCTTTTTCTATGGAAAAACGCATGGTGGGACAAAGTATTCTGCTGAACATCACCTAAATGAA TATAAAAAGAATCTGGAAGATGATATAAAGGCAATCGGTGTTCAAAGAAAGATTTCACCAAATGCCTATG AAGATCTATTAAAAGAGAAAAAAGAGCGCCTGGAACAAATCGAAAAATATATTGATTTAATCAAAGTACT CAAAGAGAAATTTGACGAGCAAAGAGAAATAGACAAACTACGCACAGAAGGAATTCCGCAATTACCTTCT GGAGTAAAGGAAGTCATTCAATCTTCTGAAAATGCCTTTGCTTTAAGGCTTTCCCCGGATAGACCAGACT CATTTACCCGCTTTGATAATCCTCTGTTTAGTCTCAAAAGAAACAGATCTCAATATGAAGCTGGGGGATA CCAACGGGCAACTGATGGATTAGGGGCTCGTTTGCGTTCTGAGCTTCTACCACCAGATAAAGACACTCCT ATTGTTTTTAATAAAAAATCACTGAAGGACAAAATCGTAGATTCTGTTTTAGCGCAACTTGACAAAGATT TTAATACAAAAGATGGCGATCGTAATCAAAAATTTGAGGATATAAAAAAACTCGTTCTAGAAGAGTACAA GAAAATTGATTCCGAACTTCAAGTGGATGAGGATACCTATCACCAACCACTTAACTTGGATTATTTGGAA AACATAGCATGTACGTTAGATGACAACTCCACCGCGAAAGATTGGGTTTATGGAATTATTGGTGCTACAA CAGAAGCTGATTATTGGCCAAAAAAGGAAAGTGAAAGTGGTACTGAAAAAGTTAGTGTATTCTATGAGAA GCAAAAGGAAATAAAATTTGAATCTGATACAAATACAATGTCAATTAAAGTCCAATATCTATTGGCTGAG ATTAATTTTTATTGTAAAACCAACAAGTTATCAGATGCTAACTTCGGTGAATTTTTTGATAAAGAGCCCC ATGCTACTGAAGTTGCTAAAAGAGTGAAAGAAGGACTTGTTCAAGGAGCAGAGATTGAGCCTATTATTTA CAATTACATTAACAGCCACTATGCCGAACTGGGATTAACATCTCAGTTAAGCAGCAAGCAACAAGAGGAA ATTACTGAAAAATTTACTCAACGTTATCACATTATTGAGAACTCTCCTCACTTTGATGAATTTTTTGTCG CTGATCCTGATAAAAAAGGGAATATATTCTCCCATCAAGGCAGAATGAGTTGCCATTTCCTGGATTTCTT CGCTCGACAAACCAAAGGCAAACATCCCCTTGGTGATCTTGCAGGTCATCAGGAAGCACTCCAGGCAGGA ACCTCCAATCGGTTACATCACAAGAATGAGGTAGTCGCTCAAGGATACGAAAAATTGGATCAATTCAAGA AAGAAGTCGTCAAACTGCTGGCAGAGAGTAAACCAAAAGAATTATTGGATTATTTGGTTGCTACCTCCCC CACAGGCGCTCCTAATTATTCCATGCTCTCAAAGGAAACTCAAAATTATATTGCTTACAACCGTAACTGG CCAGCCATTCAAACAGAGCTCGAAAAAACTACTGACATACCAGAGAACCAAAAACAAGATCTTGTAAGAT TGCTTTCTCGTAATAATCTGCAACACGAGAACCTCAGTGCAATTACCTGGTCAAAATATTCTTCCAAGCC ATTATTGGATGTGGAGTTAAATAAAATCGCCGAAGGTTTAGATCTAACTGCTAAAATTTACAATGAAAAA AGAAAAAGTGAATGGTTTAAAGGTTCAAGAAATGAGGCTCGTAAGACCCAATGTGAAGAATTGCAAAGAG TATCTCAAGAAATCAATGCTCTTCTGCAAAGTGAATCGTTAACAAAAAGCCAAGTTCTTGAAAAAGTTTT AAACTCCATAGAAGCATTGGATAAAATTGATAGAGACATTTCTGCTGAATATAATTTATTTAAGAGTACT CTGCAAAAAGAAGTACAATCATTTCGAGAGCAATTGAAAGATATCTGTCAATTAGATAACTATGCCTTTA AATCAACAAAACTTGATGAAATTATCTCTCTGGAAATGGAAGAACAATTTCAAATGATTAAAGATCCTGC TGTCCAACAAATTGTCCGAGACTTGCCTTCTCATTGTCATAATAATGAAGTGATTGAATTCTTTATGACA TTGAATCCTGAAGAAGCAGCTAAAGTAGCCAGTTATTTAAGCCTGGAATATCGTGAGATTAATAAATCCA CAGATAAGGCTAAGCTCCTGAACGAGGATATCCCCAATTTGTTTAAAGAAGTCAACATGCAGTTATTATC CAAATTAAAAGAAGATAGTGTTCTGGGAGAAGGGGTCTATGAAAAACTTGCTCAACTAGCTGATAAAATT CCTCCTGAGCATTTTACACGGAATAATATCAGAAAATGGTCTGCCAATCCTGAAAAGCTTGAGGAGTCCA ATCTCGGCGAATTATTAAAATCATCTGATAGCTCACTTTCTGAAATGGCAAGAAAATATAGAGAAACCAT AAATGAAATGACAGGAAGAAATGAGCCACCCAGAGAAACCGTTAGACACACGATATAG |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| in silico analysis literature |