SecReT4
Effector Protein ID: 54295347
T4SS name [ID]Dot/Icm [41]
Gene symbolsdcA
Locus taglpl2432
StrainLegionella pneumophila str. Lens
Repliconchromosome [GenBank: NC_006369] [Browse all T4SS(s) in this replicon]
Location [Strand]2767861..2770578 [+]
ProductSdcA protein, paralog of SidC (substrate of the Dot/Icm system)
Effector typeProtein
DescriptonSdcA
T4CP requirementT4CP Depedent
Target/EffectionA paralog of sidC which is important for Legionella-containing vacuole recruitment of endoplasmic reticulum -derived vesicles
UniProt IDQ5WTU1
KEGG IDlpf:lpl2432
PDB IDNA
Domain hit(s) vs Pfam NA
Protein Sequence: 905 a.a.     [Download]
>gi|54295347|ref|YP_127762.1| SdcA protein, paralog of SidC (substrate of the Dot/Icm system) [Legionella pneumophila str. Lens]
MVDKIKFKEPERCEYLHIDKDNKVHILLPIVGGDEIGLDNTCETTGELLAFFYGKTHGGTKYSAEHHLNE
YKKNLEDDIKAIGVQRKISPNAYEDLLKEKKERLEQIEKYIDLIKVLKEKFDEQREIDKLRTEGIPQLPS
GVKEVIQSSENAFALRLSPDRPDSFTRFDNPLFSLKRNRSQYEAGGYQRATDGLGARLRSELLPPDKDTP
IVFNKKSLKDKIVDSVLAQLDKDFNTKDGDRNQKFEDIKKLVLEEYKKIDSELQVDEDTYHQPLNLDYLE
NIACTLDDNSTAKDWVYGIIGATTEADYWPKKESESGTEKVSVFYEKQKEIKFESDTNTMSIKVQYLLAE
INFYCKTNKLSDANFGEFFDKEPHATEVAKRVKEGLVQGAEIEPIIYNYINSHYAELGLTSQLSSKQQEE
ITEKFTQRYHIIENSPHFDEFFVADPDKKGNIFSHQGRMSCHFLDFFARQTKGKHPLGDLAGHQEALQAG
TSNRLHHKNEVVAQGYEKLDQFKKEVVKLLAESKPKELLDYLVATSPTGAPNYSMLSKETQNYIAYNRNW
PAIQTELEKTTDIPENQKQDLVRLLSRNNLQHENLSAITWSKYSSKPLLDVELNKIAEGLDLTAKIYNEK
RKSEWFKGSRNEARKTQCEELQRVSQEINALLQSESLTKSQVLEKVLNSIEALDKIDRDISAEYNLFKST
LQKEVQSFREQLKDICQLDNYAFKSTKLDEIISLEMEEQFQMIKDPAVQQIVRDLPSHCHNNEVIEFFMT
LNPEEAAKVASYLSLEYREINKSTDKAKLLNEDIPNLFKEVNMQLLSKLKEDSVLGEGVYEKLAQLADKI
PPEHFTRNNIRKWSANPEKLEESNLGELLKSSDSSLSEMARKYRETINEMTGRNEPPRETVRHTI
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Nucleotide Sequence: 2718 bp     [Download]
>gi|54292964|ref|NC_006369.1|:2767861-2770578 Legionella pneumophila str. Lens, complete genome
ATGGTTGACAAAATAAAATTCAAAGAGCCGGAGCGATGCGAATATTTACATATCGATAAGGATAATAAAG
TCCATATTCTTTTACCTATTGTAGGTGGGGATGAAATAGGACTGGATAATACCTGTGAAACAACAGGTGA
GTTATTAGCCTTTTTCTATGGAAAAACGCATGGTGGGACAAAGTATTCTGCTGAACATCACCTAAATGAA
TATAAAAAGAATCTGGAAGATGATATAAAGGCAATCGGTGTTCAAAGAAAGATTTCACCAAATGCCTATG
AAGATCTATTAAAAGAGAAAAAAGAGCGCCTGGAACAAATCGAAAAATATATTGATTTAATCAAAGTACT
CAAAGAGAAATTTGACGAGCAAAGAGAAATAGACAAACTACGCACAGAAGGAATTCCGCAATTACCTTCT
GGAGTAAAGGAAGTCATTCAATCTTCTGAAAATGCCTTTGCTTTAAGGCTTTCCCCGGATAGACCAGACT
CATTTACCCGCTTTGATAATCCTCTGTTTAGTCTCAAAAGAAACAGATCTCAATATGAAGCTGGGGGATA
CCAACGGGCAACTGATGGATTAGGGGCTCGTTTGCGTTCTGAGCTTCTACCACCAGATAAAGACACTCCT
ATTGTTTTTAATAAAAAATCACTGAAGGACAAAATCGTAGATTCTGTTTTAGCGCAACTTGACAAAGATT
TTAATACAAAAGATGGCGATCGTAATCAAAAATTTGAGGATATAAAAAAACTCGTTCTAGAAGAGTACAA
GAAAATTGATTCCGAACTTCAAGTGGATGAGGATACCTATCACCAACCACTTAACTTGGATTATTTGGAA
AACATAGCATGTACGTTAGATGACAACTCCACCGCGAAAGATTGGGTTTATGGAATTATTGGTGCTACAA
CAGAAGCTGATTATTGGCCAAAAAAGGAAAGTGAAAGTGGTACTGAAAAAGTTAGTGTATTCTATGAGAA
GCAAAAGGAAATAAAATTTGAATCTGATACAAATACAATGTCAATTAAAGTCCAATATCTATTGGCTGAG
ATTAATTTTTATTGTAAAACCAACAAGTTATCAGATGCTAACTTCGGTGAATTTTTTGATAAAGAGCCCC
ATGCTACTGAAGTTGCTAAAAGAGTGAAAGAAGGACTTGTTCAAGGAGCAGAGATTGAGCCTATTATTTA
CAATTACATTAACAGCCACTATGCCGAACTGGGATTAACATCTCAGTTAAGCAGCAAGCAACAAGAGGAA
ATTACTGAAAAATTTACTCAACGTTATCACATTATTGAGAACTCTCCTCACTTTGATGAATTTTTTGTCG
CTGATCCTGATAAAAAAGGGAATATATTCTCCCATCAAGGCAGAATGAGTTGCCATTTCCTGGATTTCTT
CGCTCGACAAACCAAAGGCAAACATCCCCTTGGTGATCTTGCAGGTCATCAGGAAGCACTCCAGGCAGGA
ACCTCCAATCGGTTACATCACAAGAATGAGGTAGTCGCTCAAGGATACGAAAAATTGGATCAATTCAAGA
AAGAAGTCGTCAAACTGCTGGCAGAGAGTAAACCAAAAGAATTATTGGATTATTTGGTTGCTACCTCCCC
CACAGGCGCTCCTAATTATTCCATGCTCTCAAAGGAAACTCAAAATTATATTGCTTACAACCGTAACTGG
CCAGCCATTCAAACAGAGCTCGAAAAAACTACTGACATACCAGAGAACCAAAAACAAGATCTTGTAAGAT
TGCTTTCTCGTAATAATCTGCAACACGAGAACCTCAGTGCAATTACCTGGTCAAAATATTCTTCCAAGCC
ATTATTGGATGTGGAGTTAAATAAAATCGCCGAAGGTTTAGATCTAACTGCTAAAATTTACAATGAAAAA
AGAAAAAGTGAATGGTTTAAAGGTTCAAGAAATGAGGCTCGTAAGACCCAATGTGAAGAATTGCAAAGAG
TATCTCAAGAAATCAATGCTCTTCTGCAAAGTGAATCGTTAACAAAAAGCCAAGTTCTTGAAAAAGTTTT
AAACTCCATAGAAGCATTGGATAAAATTGATAGAGACATTTCTGCTGAATATAATTTATTTAAGAGTACT
CTGCAAAAAGAAGTACAATCATTTCGAGAGCAATTGAAAGATATCTGTCAATTAGATAACTATGCCTTTA
AATCAACAAAACTTGATGAAATTATCTCTCTGGAAATGGAAGAACAATTTCAAATGATTAAAGATCCTGC
TGTCCAACAAATTGTCCGAGACTTGCCTTCTCATTGTCATAATAATGAAGTGATTGAATTCTTTATGACA
TTGAATCCTGAAGAAGCAGCTAAAGTAGCCAGTTATTTAAGCCTGGAATATCGTGAGATTAATAAATCCA
CAGATAAGGCTAAGCTCCTGAACGAGGATATCCCCAATTTGTTTAAAGAAGTCAACATGCAGTTATTATC
CAAATTAAAAGAAGATAGTGTTCTGGGAGAAGGGGTCTATGAAAAACTTGCTCAACTAGCTGATAAAATT
CCTCCTGAGCATTTTACACGGAATAATATCAGAAAATGGTCTGCCAATCCTGAAAAGCTTGAGGAGTCCA
ATCTCGGCGAATTATTAAAATCATCTGATAGCTCACTTTCTGAAATGGCAAGAAAATATAGAGAAACCAT
AAATGAAATGACAGGAAGAAATGAGCCACCCAGAGAAACCGTTAGACACACGATATAG

Reference
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] in_silico
 
in_silico in silico analysis literature