| Effector Protein ID: 54295341 |
 T4SS name [ID] | Dot/Icm [41] |
| Gene symbol | - |
| Locus tag | lpl2426 |
| Strain | Legionella pneumophila str. Lens |
| Replicon | chromosome [GenBank: NC_006369] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2757400..2760228 [+] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | SidI/ceg32 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | SidI interacts with eEF1A and eEF1Bgamma and inhibits protein synthesis. SidI is also involved in a stress response of eukaryotic cell (Belyi, et al. 2011) |
| UniProt ID | Q5WTU7 |
| KEGG ID | lpf:lpl2426 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 942 a.a. [Download] |
| >gi|54295341|ref|YP_127756.1| hypothetical protein lpl2426 [Legionella pneumophila str. Lens] MTKIYLLTAPFDEEAKTGDGQYAASLELGFAENYEDIPCQWLKKDKGDYSIPFPTGTTSIPEDTIPSAIV LQPVANENTVISGYKLKDAVSSPEKAQEVNKKTVSPRTPKIIVKHDNSLQSLTIMDIYSQKPIQFDESKV DEIISSLDTKKVKLEKAIEDNNADLSKIKKQKSKLAYLTRLYKENKENIQDYCTLNEYIEAHLFNPKFLS RHEKALNNFKTLKSQFTGPVNLKELEKLTDKLTGIKEYSYDFHSNSLPYDLEHDKSFRNFYDFDGLKESI KSIIKELEVLNSIRQAVSDKYPNSFKALNETEEHDDKLKFINIIFNDGFSTTYDQQTFIKALSALDIEKA IDAYTNVKMKLENTQDIIANKEECRNKLISELQTLIANKQEPYLSANEKLGGFYSKRKLSASEGFHLAYQ ANRRDPIKPEVIENIITKMKPIDEDTHLDIHIRPPDCGVFITPEDIKKFQEAGIKVNITIHEYKQNYTRR YLQQYTHDLMRQANSVQFFNAEDRENAIIAATYGDCDKRNTTEPTGVAKKIREVGEDFDLDKYPVQKYDL KGKSGLTVASQKLSTEPDHPLDVVAKPPNILSFGTIRPGKGFEEALKLAQLTKDTSLSICEKINRVPIVK LAGDPQDKELMQQIVVERFGKAAVENYQKTHAYDNQFNNSQRRDYWKNLVRELNAKVKEEGAVLNNPYIE IYPWCEPHELLDLKQNCKYVCRMDDMGMRNNGSAIISVLDVGVVYTKFGSVTDDIFIKGGKYGNAVDIGE YRYGKYSLLKKEKEFKEQHEEEPLPKWLIKNPDSAYKRQSESRDPKDILDSIVAREENQLICDNIEDSDN YRTVVEAQKLLKERFTLKNAVDHLLENIGLGHLIAQEEIDELFDTVDPVQAQIDNLDVLSDIKTPRLCLS RSCPELGFFGSRRGDLATKQENNKLKESILVF |
| - |
| Nucleotide Sequence: 2829 bp [Download] |
| >gi|54292964|ref|NC_006369.1|:2757400-2760228 Legionella pneumophila str. Lens, complete genome ATGACTAAAATATACTTATTAACTGCGCCTTTTGATGAAGAGGCAAAAACTGGTGATGGGCAATACGCGG CCTCTTTGGAATTGGGTTTTGCTGAAAATTACGAAGATATACCTTGTCAATGGTTAAAAAAAGACAAAGG TGATTACTCTATCCCATTTCCAACAGGAACTACTTCCATTCCGGAAGATACTATACCAAGCGCGATAGTA TTACAGCCAGTTGCTAACGAAAATACAGTAATAAGCGGTTATAAATTAAAAGATGCTGTTTCATCTCCAG AAAAAGCACAGGAAGTAAATAAAAAAACGGTTAGTCCCAGAACACCAAAAATTATTGTAAAGCACGATAA CAGCCTGCAATCACTTACAATAATGGATATTTACTCTCAAAAACCTATTCAATTTGATGAGTCAAAAGTT GATGAAATCATTAGCTCTTTGGATACGAAAAAAGTCAAATTAGAAAAAGCTATAGAAGATAATAACGCTG ATCTGAGTAAAATTAAGAAACAAAAATCCAAATTAGCGTATTTGACTAGATTATATAAGGAAAACAAAGA GAATATTCAAGATTATTGCACCTTAAATGAATATATTGAGGCTCATTTATTTAATCCTAAATTTTTAAGC AGACATGAGAAAGCACTCAATAATTTTAAGACACTTAAAAGCCAATTTACTGGCCCTGTCAATTTAAAAG AACTGGAAAAATTAACAGATAAACTGACTGGAATTAAAGAGTACAGCTACGATTTCCATAGTAACAGTTT ACCCTATGATTTAGAGCACGATAAAAGTTTCAGAAATTTTTATGATTTCGATGGATTAAAAGAATCTATC AAAAGCATTATCAAGGAATTAGAGGTGCTTAACAGCATTCGTCAGGCTGTATCAGACAAGTACCCCAATA GCTTTAAAGCGCTAAATGAAACAGAAGAGCACGACGATAAATTAAAATTTATCAATATTATTTTCAACGA TGGATTTAGCACCACTTATGACCAACAAACCTTTATCAAGGCCTTATCAGCTCTTGATATTGAAAAGGCA ATTGACGCTTATACAAATGTTAAAATGAAACTGGAAAACACTCAGGATATTATCGCCAATAAAGAGGAGT GTAGAAATAAGTTAATTTCAGAATTACAAACTTTAATTGCAAATAAACAAGAACCTTACCTCTCTGCAAA TGAAAAGCTTGGCGGTTTTTACAGCAAAAGAAAACTCTCCGCAAGTGAAGGGTTTCATTTAGCCTATCAG GCAAACCGACGTGACCCGATAAAACCTGAAGTGATTGAAAACATTATTACCAAAATGAAGCCCATTGATG AGGATACCCATCTTGATATTCATATTCGTCCACCAGATTGCGGGGTCTTTATTACCCCAGAAGACATCAA AAAATTTCAAGAGGCAGGTATTAAAGTCAATATCACAATTCATGAATATAAACAGAACTACACTCGACGT TATTTACAACAATATACTCATGATTTAATGCGCCAGGCAAACAGTGTGCAATTCTTTAATGCAGAAGATA GAGAAAATGCTATCATTGCCGCTACTTATGGTGATTGTGATAAGCGCAATACAACTGAACCGACTGGTGT TGCAAAAAAAATAAGAGAAGTCGGGGAAGATTTTGACTTAGATAAATACCCGGTTCAAAAATATGATTTA AAAGGAAAATCAGGATTAACCGTTGCATCACAAAAATTAAGCACTGAACCGGATCATCCATTGGATGTAG TAGCCAAGCCTCCCAATATCTTATCTTTTGGTACGATTCGTCCTGGCAAAGGGTTTGAAGAAGCGTTAAA GCTGGCTCAATTGACTAAAGATACCTCTCTTTCTATTTGTGAAAAAATAAACCGAGTACCTATTGTAAAA CTGGCAGGTGACCCACAGGATAAAGAGTTAATGCAACAAATAGTTGTTGAAAGATTTGGTAAAGCAGCTG TCGAAAACTATCAAAAAACGCATGCCTATGACAATCAATTTAATAATAGTCAGCGTAGAGATTATTGGAA AAATCTGGTTAGGGAGTTAAATGCAAAAGTTAAAGAAGAAGGTGCTGTTCTTAATAATCCTTACATCGAA ATATATCCTTGGTGTGAGCCGCATGAATTGCTGGATTTAAAGCAAAACTGTAAATACGTTTGTCGAATGG ACGACATGGGCATGAGAAACAATGGCTCAGCAATTATCAGTGTATTAGACGTTGGAGTCGTTTATACTAA ATTTGGTTCTGTTACAGACGATATTTTTATTAAAGGCGGCAAATACGGCAATGCCGTTGATATTGGAGAA TATCGTTATGGGAAATACAGTCTGTTAAAAAAGGAAAAGGAATTTAAAGAACAGCATGAGGAAGAACCAC TACCTAAGTGGCTAATCAAAAATCCAGACTCTGCTTATAAGCGACAATCAGAATCGAGAGATCCAAAGGA TATTTTAGACTCCATTGTCGCAAGAGAAGAAAATCAATTAATATGTGATAATATAGAAGATTCCGATAAT TATCGAACAGTAGTCGAAGCACAAAAGTTATTAAAAGAGCGCTTTACACTTAAAAATGCTGTAGATCATT TATTAGAGAATATAGGACTCGGCCATTTAATTGCTCAAGAAGAGATCGATGAATTATTTGATACTGTTGA TCCAGTACAAGCACAAATAGATAATTTAGATGTTCTTTCTGATATTAAGACACCACGTCTGTGTTTATCA CGCTCTTGCCCTGAATTAGGTTTTTTTGGCTCACGTCGTGGTGACTTGGCGACTAAACAAGAAAATAATA AACTTAAAGAATCGATACTGGTATTTTGA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| in silico analysis literature |