| Effector Protein ID: 54295299 |
 T4SS name [ID] | Dot/Icm [41] |
| Gene symbol | - |
| Locus tag | lpl2384 |
| Strain | Legionella pneumophila str. Lens |
| Replicon | chromosome [GenBank: NC_006369] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2713562..2715481 [-] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | SidM/drrA |
| T4CP requirement | T4CP Depedent |
| Target/Effection | DrrA is necessary for Rab1 recruitment and binds specifically to GDP-bound Rab1 (Machner & Isberg 2006, Murata et al. 2006) |
| UniProt ID | Q5WTY9 |
| KEGG ID | lpf:lpl2384 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NTP_transf_2 [PF01909], Evalue: 6.8e-05, Aligned region: 83..115 |
| Protein Sequence: 639 a.a. [Download] |
| >gi|54295299|ref|YP_127714.1| hypothetical protein lpl2384 [Legionella pneumophila str. Lens] MSVNEEQFGSLYSDERDKPLLSPTAQKKFEEYQNKLANLSKIIRENEGNEVSPWQEWENGLRQIYKEMIY DAFDALGVEMPKDMEVHFAGSLAKAQATEYSDLDAFVIVKNDEDIKKVKPVFDALNNLCQRIFTASNQIY PDPIGINPSRLIGTPDDLFGMLKDGMVADVEATAMSILTSKPVLPRYELGEELRDKIKQEPSFSNMVSAK KFYNKAIKDFTAPKEGAEVVSVKTHIMRPIDFMLMGLREEFNLYSEDGAHLSAPGTIRLLREKNLLPEEQ IARIESVYNQAMSKRFELHAEHKKEHDEMPYSDAKAMLDEVAKIRELGVQRVTRIENLENAKKLWDNANS MLEKGNISGYLKAANELHKFMKEKNLKEDDLRPELSDKTISPKGYAILQSLWGAASDYSRAAATLTESTV EPGLVSAVNKMSAFFMDCKLSPNERATPDPDFEVGKSKILVGIMQFIKDVADPTSKIWMHNTKALMNHKI AAIQKLERSNNVNDETLESVLSSKGENLSEYLSYKYATKDEGREHRYTASTENFKNVKEKYQQMRGDALK TEILADFKDKLAEATDEQSLKQIVAELKGKDEYKILAKGQGLTTQLLGLKTSSVSAFEKMVEETRESIKS QERQTIKIK |
| - |
| Nucleotide Sequence: 1920 bp [Download] |
| >gi|54292964|ref|NC_006369.1|:c2715481-2713562 Legionella pneumophila str. Lens, complete genome ATGAGTGTTAATGAAGAGCAATTTGGTAGTTTATACAGTGATGAGCGAGACAAACCATTACTATCCCCAA CCGCTCAGAAAAAATTTGAAGAATATCAGAACAAATTGGCGAATCTAAGTAAAATAATTCGAGAAAATGA GGGCAATGAAGTATCTCCATGGCAGGAGTGGGAGAATGGATTACGTCAAATTTACAAAGAAATGATTTAT GATGCTTTTGACGCGCTTGGTGTCGAGATGCCGAAAGATATGGAAGTCCATTTTGCAGGTTCTCTTGCCA AGGCACAAGCCACTGAGTATAGTGATTTGGATGCCTTTGTTATTGTTAAAAATGACGAAGATATAAAAAA AGTAAAACCGGTCTTTGACGCATTAAATAATTTATGTCAGCGTATTTTTACTGCAAGCAATCAGATATAT CCTGATCCTATTGGAATCAATCCAAGCCGTCTTATTGGTACGCCTGATGATTTGTTTGGTATGTTAAAAG ACGGGATGGTAGCTGATGTTGAAGCAACTGCAATGTCAATTTTAACATCAAAACCTGTTCTACCTCGCTA TGAATTAGGAGAAGAGTTACGAGATAAAATCAAACAAGAACCTTCTTTCAGCAATATGGTTTCAGCCAAG AAGTTTTATAATAAAGCCATTAAAGACTTTACTGCACCTAAAGAGGGTGCAGAAGTAGTGAGTGTCAAAA CTCATATTATGCGTCCCATCGATTTTATGCTGATGGGATTGCGTGAGGAATTTAATTTATACAGCGAGGA TGGAGCCCATCTTTCAGCACCAGGAACTATACGGTTATTACGTGAAAAAAATTTATTGCCCGAAGAGCAA ATCGCTCGAATCGAGTCAGTATACAATCAAGCGATGAGCAAGAGATTTGAGTTGCATGCTGAGCATAAAA AAGAACACGATGAGATGCCTTATTCTGATGCTAAAGCAATGCTTGATGAGGTAGCCAAAATAAGAGAGCT GGGTGTTCAACGTGTCACAAGGATTGAAAATCTGGAAAATGCCAAGAAGTTGTGGGACAACGCGAATAGC ATGCTTGAGAAGGGTAACATCAGCGGATATCTTAAAGCAGCGAATGAGCTTCATAAATTTATGAAGGAAA AAAATCTTAAGGAAGATGATTTAAGGCCAGAGTTGAGTGATAAAACAATATCTCCAAAAGGATATGCTAT TTTACAATCTTTATGGGGAGCAGCTTCGGATTATAGTAGAGCGGCTGCAACTCTCACAGAATCAACAGTA GAGCCTGGTTTAGTATCAGCTGTTAACAAAATGTCAGCATTCTTTATGGATTGTAAATTAAGTCCAAATG AGCGAGCAACCCCTGATCCAGATTTTGAGGTAGGGAAATCTAAAATTTTAGTAGGTATAATGCAATTCAT AAAAGATGTAGCAGACCCAACTTCGAAAATATGGATGCATAATACAAAAGCTTTGATGAATCATAAAATT GCTGCTATTCAAAAACTTGAGAGAAGCAATAATGTTAATGATGAAACATTAGAGAGTGTGCTGAGCTCTA AAGGTGAAAATTTATCCGAATATCTTTCTTATAAATACGCAACAAAAGATGAAGGAAGAGAGCACCGCTA TACGGCAAGCACGGAAAATTTTAAAAATGTTAAAGAAAAATATCAGCAAATGCGAGGTGATGCTTTAAAA ACAGAAATTCTGGCTGATTTCAAGGATAAACTGGCTGAAGCTACCGATGAACAGAGCCTTAAGCAAATTG TTGCTGAATTGAAAGGTAAAGATGAATATAAAATTTTGGCTAAGGGGCAAGGGTTAACAACCCAACTTTT AGGGCTAAAAACAAGTTCCGTGTCCGCATTTGAGAAAATGGTTGAGGAAACAAGAGAAAGTATTAAGTCT CAAGAAAGACAAACCATTAAGATAAAATAA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
|
| in silico analysis literature |