| Effector Protein ID: 54295005 |
 T4SS name [ID] | Dot/Icm [41] |
| Gene symbol | sdeA |
| Locus tag | lpl2085 |
| Strain | Legionella pneumophila str. Lens |
| Replicon | chromosome [GenBank: NC_006369] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2360178..2364809 [+] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | LaiA/SdeA |
| T4CP requirement | T4CP Depedent |
| Target/Effection | An integrin-like protein involved in adhesion to and invasion of human lung alveolar epithelial cells. (Chang et al. 2005) |
| UniProt ID | Q5WUT3 |
| KEGG ID | lpf:lpl2085 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | SidE [PF12252], Evalue: 0, Aligned region: 1..512 SidE [PF12252], Evalue: 0, Aligned region: 517..1483 |
| Protein Sequence: 1543 a.a. [Download] |
| >gi|54295005|ref|YP_127420.1| hypothetical protein lpl2085 [Legionella pneumophila str. Lens] MPKYVEGVELTQEGMHAIFARMGYGNITSGSIYNGRPTINTLALNNQGFMPVLTGVGPHRDSGHWIMLIK GPGNQYYLFDPLGKASGEGYQNILAAQLPMGSTLSVIPNDSGLNMGLCGYWVASAGLRAHQTLNQHNPPT LLNLGQTITDEMRNELDHDGYRKITGWLRAVADEFPEGDPQLDGKALRENTEKDLKIEIPTLVLPGKDTS PKEISVKPTAPQDKSVPVWNGFSLYTDETVRTAAQYAYDNYLGKPYTGPVESAPANFGGQMVYRQHHGLS HTLRTMAYAELIVEEARKAKLRGETLGKFKDGRTIADVTPQELKKIMIAQAFFVTGRDDEESEKNYAKYH QQSRDAFLKYVKDNESTLIPDVFKDQEDVNFYAMVIEDKKKDWDSTPAHVLINQGHMVDLVRVKQPPESY LESYFKSMQRWIGTQATEAVFATQRQFFHATYEAVTGFDSDNKEPHLVTSGQFRYVIGEDGKPIREAPKM GQKEGNIKFFPPTYKLKGKERFEFGNAGLGRYVIGEDGQPIRNEPAKGEKQGTLAFFPSTYQLQGNERFM RVDEYLKLDEVQQRFPGIGKHLEGGMPGMNEMDYWNRLNSLNRARCENDVDFCLKQLQTAHDKAKIDPVK EAFQSSKEKGRRQPNVDEIAAARIIQQILANPDCIHDDHVLINGQKLEQQFFRDLLAKCEMAVVGSLLND TDMGNIDTLMRHEKDTEFHSTNPEAVPVKIGEYWINDQNKYNSSGNITQKKHDLIFLMQNDAWYFSRVNA IAQNRDKGSTFKEVLITTLMTPLTSKALVDTSRAPAPKRLLRGLNFSEEYAQGLINQANAMIANTTERLF TDHSPEAFKQIKLNDLSKMSGRTNASTTTDMKLLTETWDSNVIFEMLDPDGLLHPKQVGRHGEGTESEFS IYLPEDVALVPIKVTLDEGKTKNGGNRYIFTFVAVKSPDFIPRHENGYAVEPFLRMQTAKLAEVKSSVEK AQRAPDLETIFNLQNEVEAVQYSHLSTGYKNFLKNTVGPVLENSLSGLMESDPVALSKALAAFPSDTQWS AFNFEEARQAKRQMDAIKQMVGNKVVLDALTQCQDAMEKQNIAGALDALKSIPSESTISREQREQIQSIR QDLESLQRAVVTPVVTDEKKVKERYDALIENTSKKITELETGKLPNLDAVKKGISNLSNLKQEVTVLRNE KIRMHVGTDKVDFSDIEKLEQQIQVMDTKLTDAYLLEVTKQISALENAKPKNQTELKTKIAAFLDRTADI ETLRNDRIKKHGSSKDPLDLSDLDKLSGNLQRINQSIVSSLINTIRVSINQMEAKTFHMQEKEIQQNFEL LTKLEKTLDKSKTSEKLREDIPKLNDLLVAKQKAYPQMVQLQLKSEVFVTQLREVCQANYDDLDKTRNAR LRELDRLDREAGITRMVGNLLWGFTNKVGLTTDERLDIRTKQQSLARFRTELFNDKIDTDELISNLARKR PSELQEGLGISPDNAMDLYMVLTNLESKTTSPEKLEERMKAIDDISTKIGREPEHLKFVMVEEDESNKKT IGF |
| - |
| Nucleotide Sequence: 4632 bp [Download] |
| >gi|54292964|ref|NC_006369.1|:2360178-2364809 Legionella pneumophila str. Lens, complete genome ATGCCTAAGTATGTCGAAGGGGTAGAACTAACTCAAGAAGGTATGCATGCTATTTTTGCACGCATGGGGT ATGGCAATATTACCAGCGGTAGTATTTACAATGGAAGACCGACTATTAACACACTAGCCCTGAACAACCA GGGATTTATGCCTGTGTTAACCGGGGTAGGGCCACATAGAGACTCCGGACACTGGATTATGTTAATCAAA GGTCCCGGTAACCAATACTATCTCTTTGACCCACTGGGTAAAGCTTCGGGTGAAGGCTATCAAAATATTT TAGCAGCACAATTACCCATGGGATCTACCCTTTCAGTTATTCCTAATGATTCCGGTTTGAATATGGGGTT ATGCGGCTATTGGGTCGCCTCTGCCGGTTTAAGAGCACACCAGACATTAAATCAACATAATCCCCCTACT TTGTTGAATCTAGGACAAACCATTACCGATGAAATGCGTAATGAACTCGATCATGACGGTTATCGAAAAA TTACCGGATGGTTACGTGCTGTTGCGGATGAATTCCCTGAAGGTGACCCACAATTGGATGGGAAAGCATT AAGAGAAAACACTGAAAAAGATTTAAAAATAGAAATTCCTACCCTGGTTCTTCCGGGAAAAGATACCTCC CCTAAAGAAATTTCTGTCAAACCCACTGCACCACAAGATAAATCTGTGCCTGTTTGGAATGGATTTTCAT TGTATACCGATGAAACCGTTCGGACTGCAGCACAATACGCCTATGACAATTATCTGGGAAAACCCTATAC CGGACCAGTGGAATCAGCACCCGCAAATTTTGGTGGGCAAATGGTGTATAGACAACATCATGGACTTTCC CATACTTTACGGACCATGGCTTATGCGGAATTGATTGTTGAAGAAGCACGTAAAGCTAAATTACGGGGTG AAACATTAGGGAAATTCAAAGATGGACGTACTATTGCTGATGTTACCCCTCAAGAACTAAAAAAAATCAT GATTGCCCAGGCATTTTTTGTCACTGGAAGAGATGATGAGGAATCCGAAAAAAATTATGCCAAATACCAT CAGCAAAGCCGCGACGCTTTCTTAAAGTATGTGAAAGACAATGAATCCACCTTAATTCCTGATGTTTTCA AAGATCAGGAAGATGTCAATTTTTATGCGATGGTAATTGAAGATAAAAAGAAAGATTGGGATTCAACTCC AGCGCATGTATTGATTAATCAGGGCCATATGGTCGATTTGGTGCGGGTCAAACAACCACCTGAATCCTAT CTGGAAAGTTATTTCAAATCCATGCAACGCTGGATAGGTACTCAGGCAACGGAAGCTGTTTTTGCGACAC AAAGACAATTTTTCCATGCCACTTATGAAGCAGTAACAGGTTTTGACTCTGATAACAAAGAACCTCATCT GGTGACATCTGGTCAATTCCGTTATGTCATCGGTGAAGACGGTAAGCCCATTAGAGAAGCACCCAAAATG GGGCAAAAAGAAGGTAACATAAAATTTTTTCCTCCTACATACAAACTAAAAGGAAAAGAACGTTTTGAAT TCGGAAATGCAGGTCTTGGTCGCTATGTCATCGGTGAAGATGGCCAACCTATCAGAAATGAACCCGCAAA AGGCGAGAAACAGGGTACATTAGCCTTTTTCCCTTCCACTTATCAGCTACAAGGTAATGAACGCTTTATG CGGGTGGATGAATATCTCAAACTGGATGAAGTACAACAGCGATTCCCCGGGATTGGCAAACATCTGGAAG GTGGAATGCCAGGTATGAATGAAATGGATTATTGGAATCGACTGAACTCTTTAAACAGAGCACGATGCGA AAACGATGTTGATTTTTGTTTGAAACAATTACAAACAGCCCATGACAAGGCGAAAATTGATCCTGTTAAA GAAGCCTTTCAATCCAGCAAAGAGAAAGGAAGAAGACAACCTAATGTTGATGAAATTGCTGCTGCCCGCA TCATTCAGCAAATCTTGGCCAATCCTGATTGCATCCATGATGATCATGTGCTCATCAATGGCCAGAAACT GGAACAACAATTCTTCCGCGATTTGTTAGCCAAATGTGAAATGGCTGTTGTAGGCTCACTGCTCAATGAC ACCGACATGGGAAACATTGATACTTTAATGCGACATGAGAAAGACACCGAGTTTCATTCTACCAATCCTG AAGCAGTTCCGGTGAAAATTGGAGAATATTGGATTAATGACCAAAATAAATACAATAGTAGTGGCAATAT CACCCAAAAGAAACACGATTTAATTTTCCTCATGCAAAATGATGCGTGGTATTTTAGCCGAGTCAATGCC ATCGCACAAAATAGGGATAAAGGCTCCACTTTCAAGGAAGTGCTGATTACTACTTTAATGACGCCTTTGA CGAGTAAAGCACTAGTGGATACGTCACGCGCCCCTGCTCCGAAAAGACTGCTTCGTGGATTAAATTTTTC AGAAGAATATGCTCAGGGATTAATCAATCAAGCCAATGCAATGATTGCCAATACGACAGAGCGTCTATTC ACCGATCATTCACCAGAAGCCTTCAAACAGATTAAGTTAAATGATTTAAGTAAAATGTCCGGCAGAACTA ATGCCAGTACGACTACAGATATGAAGCTTTTAACAGAAACCTGGGACTCCAATGTCATTTTTGAAATGCT TGACCCGGATGGTTTGCTGCATCCCAAGCAAGTAGGGCGCCATGGGGAGGGCACTGAAAGTGAATTCTCC ATTTATTTGCCAGAAGATGTTGCCCTGGTCCCAATCAAAGTGACTCTTGATGAAGGTAAAACAAAAAATG GAGGAAATCGATATATCTTTACCTTTGTTGCCGTAAAAAGCCCTGACTTTATACCACGTCATGAAAACGG CTATGCGGTTGAACCGTTTTTAAGAATGCAAACTGCCAAGTTAGCCGAAGTCAAAAGCTCTGTTGAAAAA GCCCAGAGAGCACCTGACCTTGAGACAATTTTCAATTTACAAAACGAAGTAGAAGCAGTGCAATACTCAC ACTTATCGACGGGTTACAAAAATTTTCTAAAAAACACCGTTGGTCCTGTTTTAGAAAATAGTCTTAGTGG ACTCATGGAGAGTGACCCGGTCGCTTTAAGTAAAGCATTAGCAGCATTTCCATCCGATACACAATGGTCA GCCTTCAATTTTGAAGAAGCAAGGCAAGCCAAAAGACAGATGGATGCCATTAAGCAAATGGTTGGAAATA AAGTGGTGCTTGACGCCTTGACTCAATGCCAGGACGCCATGGAAAAGCAAAACATTGCTGGCGCATTGGA TGCGCTCAAAAGCATCCCATCTGAGAGTACGATAAGCAGAGAGCAAAGAGAGCAAATACAGAGCATCAGG CAAGACCTGGAATCATTGCAACGTGCTGTCGTTACCCCGGTAGTAACAGATGAAAAGAAAGTAAAAGAAC GCTATGATGCCCTGATAGAAAACACATCGAAGAAAATTACTGAACTTGAAACAGGGAAATTACCCAATCT TGATGCTGTCAAGAAAGGCATATCTAACTTGAGCAACCTGAAACAAGAAGTAACCGTATTACGTAATGAA AAAATACGGATGCACGTTGGAACTGATAAAGTTGATTTTTCAGATATTGAAAAACTGGAGCAACAAATAC AGGTCATGGATACCAAATTAACCGATGCTTATTTACTTGAAGTAACCAAACAAATTTCAGCGCTTGAAAA TGCAAAACCCAAAAATCAGACTGAATTGAAAACAAAAATAGCAGCATTCCTTGACAGAACCGCTGATATT GAGACCTTGCGTAATGATCGCATCAAAAAACACGGTTCATCGAAAGATCCGCTCGACCTCTCTGATTTGG ATAAATTAAGCGGCAACTTACAGCGCATCAATCAATCCATTGTTTCGTCTTTGATAAATACTATCCGGGT TTCTATCAATCAAATGGAAGCGAAAACTTTTCACATGCAAGAAAAGGAAATACAACAGAATTTCGAGTTA CTCACAAAACTCGAAAAAACATTGGATAAGTCAAAGACATCAGAGAAACTGAGAGAGGACATTCCCAAAC TCAATGATTTGCTGGTTGCAAAACAAAAAGCCTATCCTCAAATGGTACAACTGCAACTCAAGAGCGAAGT CTTTGTCACACAATTACGTGAGGTATGTCAAGCTAACTATGACGATCTGGATAAAACAAGAAATGCAAGA TTACGAGAACTGGATCGACTGGACAGAGAAGCTGGAATAACAAGAATGGTGGGCAATCTGTTATGGGGGT TTACCAACAAAGTAGGCTTAACCACAGATGAACGACTTGACATCAGGACTAAACAACAATCGCTTGCACG ATTCAGGACTGAATTATTCAATGATAAGATTGATACGGATGAACTAATCTCTAATTTAGCAAGGAAAAGA CCTTCTGAACTGCAAGAAGGATTGGGAATATCTCCTGACAATGCGATGGATTTATATATGGTCTTAACTA ATTTGGAGTCTAAAACCACTTCTCCAGAAAAACTTGAAGAAAGAATGAAAGCAATCGATGACATTTCCAC CAAGATAGGTAGAGAGCCTGAGCATTTGAAATTTGTCATGGTTGAAGAAGATGAATCCAATAAAAAAACT ATAGGATTTTAA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| in silico analysis literature |