| Effector Protein ID: 54294874 |
 T4SS name [ID] | Dot/Icm [41] |
| Gene symbol | - |
| Locus tag | lpl1953 |
| Strain | Legionella pneumophila str. Lens |
| Replicon | chromosome [GenBank: NC_006369] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2191194..2192636 [+] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | PieG/legG1 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | LegG1 has an RCC1 domain which can act as a guanine-nucleotide dissociation stimulator for the Ran GTP-binding protein (de Felipe, et al. 2005) |
| UniProt ID | Q5WV64 |
| KEGG ID | lpf:lpl1953 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | RCC1 [PF00415], Evalue: 1.1e-26, Aligned region: 255..283 RCC1 [PF00415], Evalue: 1.1e-26, Aligned region: 312..357 RCC1 [PF00415], Evalue: 1.1e-26, Aligned region: 369..413 |
| Protein Sequence: 480 a.a. [Download] |
| >gi|54294874|ref|YP_127289.1| hypothetical protein lpl1953 [Legionella pneumophila str. Lens] MPDVRGSPDANQIPDDIWLDILINYLQPQDIVSLSEVNNRLSRLFKTQHTQSEQLNRKKTLGILKVFAGY SSTFLFARLNGKQRLFKTRNSSVVDSDNINPILMPISLPENISFIESIQSTSNHTVLVGRDSHDHIIVAT NKINQDYAGQETSHNQVISLPLHDNNISLVSAGNEENYILNPIFLFSRNTRGQLSLASYKTNDRIPLGTT IGERNHPLPIIPLPYTMKTVKQIHSGIWHNVIRGYDQYNRPQIATFGKNYDGQLGTGDWENRDTPTLIKL PPEMFTLHVIETSFFHTIAIGLDKNGFPIVASCGYNSDGQLGCGDKDNKNTLNPIKIPENMKSVEMVATG IKHTVIVGKDINNKPVVATCGHNGYGQLGTGDEQNRVCLTPIPIPKDLITIDYVEAGAYHTVICGRNIKN QPIIALCGCNSNGELGFAPQKIAKKSSLMTNPALFFPPRPDKGTINNLMKISKFSPCNLL |
| - |
| Nucleotide Sequence: 1443 bp [Download] |
| >gi|54292964|ref|NC_006369.1|:2191194-2192636 Legionella pneumophila str. Lens, complete genome ATGCCTGATGTTCGCGGCAGCCCTGATGCAAACCAAATTCCAGATGATATCTGGCTTGACATTCTTATCA ATTATCTTCAACCACAAGATATTGTGAGCCTGTCTGAAGTCAACAATCGCTTGAGCAGACTTTTCAAAAC TCAACACACTCAATCTGAGCAATTGAACCGAAAAAAAACATTGGGAATTCTGAAAGTATTTGCAGGATAC AGTTCCACTTTCCTGTTTGCACGCCTCAATGGTAAGCAAAGATTATTTAAAACCAGAAATTCGAGTGTGG TGGATAGCGATAACATAAACCCAATATTAATGCCCATCTCTCTGCCAGAGAACATCTCTTTTATTGAATC CATTCAATCAACATCCAACCACACCGTGCTTGTTGGTCGAGACAGTCATGATCATATTATAGTGGCAACA AACAAAATCAATCAGGATTATGCAGGGCAAGAAACCAGTCACAACCAAGTAATTTCCCTTCCGTTACACG ACAATAACATTTCTCTGGTATCTGCCGGGAATGAAGAGAACTATATTTTAAACCCTATTTTTCTCTTTTC CCGCAATACAAGAGGGCAATTGAGTCTTGCATCCTACAAAACAAATGACAGAATACCATTAGGAACCACA ATTGGGGAAAGAAACCACCCGTTACCCATCATACCATTGCCTTACACTATGAAAACAGTAAAACAAATAC ATTCAGGAATATGGCATAATGTGATTAGAGGCTATGATCAATATAATCGACCGCAAATTGCTACTTTTGG AAAAAATTACGATGGGCAATTAGGCACAGGCGATTGGGAAAACAGAGATACACCTACCCTGATAAAGCTT CCTCCTGAAATGTTTACACTTCATGTAATTGAAACCAGTTTTTTTCACACCATTGCCATTGGACTTGATA AAAATGGATTCCCTATCGTTGCAAGCTGCGGTTATAACTCCGATGGCCAATTGGGATGCGGGGATAAAGA TAATAAAAACACATTGAATCCCATCAAAATTCCAGAAAATATGAAATCAGTAGAAATGGTCGCCACTGGA ATAAAACACACCGTTATTGTGGGAAAAGACATAAATAACAAGCCTGTGGTTGCAACCTGTGGGCATAACG GCTATGGACAACTGGGTACAGGCGATGAACAAAACCGAGTCTGCTTGACTCCCATTCCAATTCCCAAGGA CCTAATTACAATTGATTATGTTGAAGCCGGCGCCTATCATACAGTCATTTGTGGGCGGAATATAAAAAAT CAGCCAATTATAGCCTTATGTGGGTGTAATTCAAACGGTGAATTGGGGTTTGCACCGCAAAAAATCGCAA AGAAATCATCCCTGATGACCAACCCGGCCCTGTTTTTTCCGCCGCGACCAGACAAGGGCACAATAAATAA TTTAATGAAAATTAGTAAATTCTCGCCATGTAATTTGCTATGA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| in silico analysis literature |