Effector Protein ID: 54293915 |
T4SS name [ID] | Dot/Icm [41] |
Gene symbol | lidA |
Locus tag | lpl0971 |
Strain | Legionella pneumophila str. Lens |
Replicon | chromosome [GenBank: NC_006369] [Browse all T4SS(s) in this replicon] |
Location [Strand] | 1086944..1089133 [-] |
Product | LidA protein, substrate of the Dot/Icm system |
Effector type | Protein |
Descripton | LidA |
T4CP requirement | T4CP Depedent |
Target/Effection | LidA may be involved in vesicle recruitment during the biogenesis of the replication vacuole |
UniProt ID | Q5WXW8 |
KEGG ID | lpf:lpl0971 |
PDB ID | NA |
Domain hit(s) vs Pfam | NA |
Protein Sequence: 729 a.a. [Download] |
>gi|54293915|ref|YP_126330.1| LidA protein, substrate of the Dot/Icm system [Legionella pneumophila str. Lens] MAKDNKSHQVKTSEGSLQSVKTKEKEPVVEKMRVEDSKKEDKLSMPTTKKESQPNEPVKPFKTSFEKWIE SSLLDPQAKEDRGSTINLGREGLKNASQVKKFLLSPAGKDVIAELGAQMALQRNINLQNQQDRMEHELFK RRLMAALFLWYLSKKSHAAEKVKEIIREYNEKAIKNAEKASKPSQKSTSSTAQADKEIQKMLDEYEQAIK RAQENIKKGEELEKKLDKLERQGKDLEDKYKTYEENLEGFEKLLSDSEELSLSEINEKMEAFSKDSEKLT QLMEKHKGDEKTVQSLQREHHGIKAKLANLQVLHDAHTGKKSYVNEKGNPVSSLKDAHLAINKDQEVVEH EGQFYLLQKGQWDAIKNDPAALEKAQKDYSQSKHDLATIKMEALIHKLSLEMEKQLETINDLIMSTDPEK NEEATKLLHKHNGLNLKLANLHDMLAVHRKEKSFFNEKGEEVTSLNDAHYVIGKDQQLFNLGGKFYPIHK EQKILEKDGKFYLLKQGEDWESIKDSPEKQKKAEHDFHKLQYETPMTVKKLVHHNKGLETTIHKERIEET KQQLEDNGKEKIEIANNISKLQSTVGTALNELNQSNINQESVTLTPLGGGGTTLSPKPGPSLAAVTTFFR TKIQEMKEMNSPGMTRDELRQFQSQIPEGAARNYFISALTQMPRTGPVPFQIMQAMLRNLERFGVDTTKP GVTSIRSKTDEVVEQRFNPTPSLSPFKTS |
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Nucleotide Sequence: 2190 bp [Download] |
>gi|54292964|ref|NC_006369.1|:c1089133-1086944 Legionella pneumophila str. Lens, complete genome ATGGCAAAAGATAACAAATCACATCAAGTTAAAACATCAGAAGGGAGTCTTCAATCTGTAAAAACCAAGG AAAAGGAACCTGTTGTAGAAAAAATGCGTGTTGAGGATAGTAAAAAAGAAGATAAACTATCAATGCCCAC CACTAAAAAAGAATCTCAACCCAATGAGCCAGTCAAGCCCTTTAAAACTTCTTTTGAGAAATGGATAGAA TCCAGCTTGCTTGATCCACAGGCTAAGGAAGACAGGGGCTCCACCATTAATCTGGGCCGAGAAGGGTTAA AAAACGCATCCCAGGTCAAAAAATTTCTTTTATCTCCGGCGGGTAAAGACGTAATAGCTGAGTTAGGTGC CCAAATGGCTCTGCAAAGAAACATCAATCTACAAAATCAACAAGACAGAATGGAGCATGAGCTCTTTAAA CGTCGATTAATGGCCGCTTTGTTTTTGTGGTATTTATCCAAAAAATCCCATGCTGCAGAAAAAGTCAAGG AAATTATTCGAGAATACAATGAAAAAGCCATAAAAAATGCTGAAAAAGCAAGCAAGCCAAGCCAAAAGTC CACTTCATCCACTGCACAAGCTGATAAAGAAATTCAAAAAATGCTGGATGAATATGAACAAGCTATTAAA CGTGCTCAAGAGAATATTAAGAAAGGTGAAGAATTAGAAAAAAAACTGGATAAACTGGAACGCCAAGGCA AAGATCTTGAAGACAAGTACAAAACCTATGAAGAAAATTTGGAAGGATTTGAAAAGCTTCTTTCTGATTC TGAAGAGTTATCACTATCCGAAATTAATGAAAAAATGGAAGCCTTCAGCAAAGACAGTGAGAAACTCACG CAACTGATGGAAAAGCATAAAGGCGATGAGAAAACCGTTCAATCCTTACAGCGTGAGCATCATGGCATAA AAGCAAAACTGGCTAACCTGCAAGTTTTACATGACGCTCATACAGGTAAAAAATCCTATGTTAACGAAAA AGGAAACCCGGTCAGCTCATTAAAAGACGCCCACCTAGCCATAAATAAAGACCAGGAAGTAGTAGAACAT GAAGGACAATTCTATCTCCTGCAAAAAGGTCAATGGGATGCCATTAAGAATGATCCTGCAGCATTAGAAA AAGCCCAAAAAGACTATAGCCAATCTAAACATGATCTTGCAACCATCAAGATGGAAGCTCTAATTCATAA GCTTAGTTTGGAAATGGAAAAACAATTGGAAACAATAAATGATCTTATTATGAGCACAGATCCAGAAAAG AATGAGGAAGCCACCAAATTACTGCATAAACATAATGGATTAAATTTAAAATTGGCAAATCTACATGACA TGCTTGCAGTACATAGAAAAGAAAAATCCTTTTTTAATGAGAAAGGAGAGGAAGTGACCTCATTAAATGA TGCGCATTACGTGATAGGAAAAGATCAACAACTGTTTAATTTAGGCGGTAAATTCTATCCTATCCATAAA GAACAAAAAATACTTGAAAAAGACGGCAAATTTTATCTTTTAAAACAAGGTGAAGACTGGGAATCTATCA AAGATAGCCCGGAAAAACAAAAAAAAGCTGAGCATGATTTTCATAAACTTCAGTATGAAACACCAATGAC CGTCAAGAAATTAGTACATCATAATAAAGGTTTAGAAACAACCATTCATAAAGAACGAATTGAAGAGACA AAACAACAATTAGAAGACAATGGAAAAGAAAAAATAGAGATTGCTAATAACATAAGTAAACTTCAATCTA CAGTTGGTACTGCTTTAAATGAACTAAACCAATCTAACATCAATCAAGAGTCAGTAACTTTGACTCCATT GGGAGGAGGTGGCACGACTCTTTCACCAAAACCAGGACCAAGTCTTGCTGCAGTCACTACCTTCTTCAGA ACCAAAATACAAGAAATGAAGGAAATGAATAGCCCAGGGATGACTCGTGATGAACTGCGCCAATTCCAAA GTCAAATTCCTGAAGGGGCAGCACGCAACTATTTTATAAGCGCACTCACTCAGATGCCACGCACTGGCCC AGTTCCGTTCCAAATAATGCAAGCTATGTTGCGCAACCTGGAGAGATTTGGGGTAGACACTACAAAACCC GGTGTGACTTCTATAAGAAGCAAAACAGATGAGGTTGTTGAACAACGATTTAACCCCACTCCGTCTTTAT CTCCATTCAAGACATCATAA |
Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] |
in silico analysis literature |