SecReT4
Effector Protein ID: 54293680
T4SS name [ID]Dot/Icm [41]
Gene symbol-
Locus taglpl0733
StrainLegionella pneumophila str. Lens
Repliconchromosome [GenBank: NC_006369] [Browse all T4SS(s) in this replicon]
Location [Strand]831245..832903 [-]
Producthypothetical protein
Effector typeProtein
DescriptonLem3
T4CP requirementT4CP Depedent
Target/EffectionLem3 reverses AnkX-mediated modification on Rab1 as a dephosphorylcholinase (Tan, et al, 2011)
UniProt IDQ5WYK3
KEGG IDlpf:lpl0733
PDB IDNA
Domain hit(s) vs Pfam NA
Protein Sequence: 552 a.a.     [Download]
>gi|54293680|ref|YP_126095.1| hypothetical protein lpl0733 [Legionella pneumophila str. Lens]
MRDKIITGKKIIFSQSVAKDQTKNISSFLSERFYSVNQSHNHSIIIGSSLSHQENDIEHDTILDTSGVLV
TTDTNGIVNGARVAITDGLGGGNGDQEEDDEIYRVSHSSCANFLNCDQNIDTTLSLITQPKASDKKQTAP
KTLQHTEASMAAFIYQNHPGKGYIGEFANIGDGLIIILDKRFKIKHMISACHIYRGFGTWTPPSLQALAT
TINKDALLVRQTLELAEGDIIISMTDGVWGELKTSLIAQTNDRREIGVDKEYFKTLFDELTDAPYPSSFD
IARIITHSAMSRSLERRKTLIKLINEIEQQHFHEKSVKTINEILEYFIKTDHVETAQTLKAILFEDGLSD
GVTYFENIEIPLEMVMHDLKNRTVGDCSTINVTRIPYHLDELIRGFINYPEKHQILAPLFKARVKSEADL
EEAFHRLSLEMIQPEIECPISEAHFERVFKKETLDKTQAVLTHYFRISTGLDSKKNYQERLNDLSAYLSK
ESSLEKNDIKLLLSMLDSEIKPKTGVFQTLFGENQNKLYKAFHKKIELQLLDGEIENKNELK
-
Nucleotide Sequence: 1659 bp     [Download]
>gi|54292964|ref|NC_006369.1|:c832903-831245 Legionella pneumophila str. Lens, complete genome
ATGAGAGATAAAATTATCACCGGGAAAAAAATTATTTTTTCACAATCCGTTGCAAAAGACCAAACAAAAA
ATATATCAAGCTTTTTATCAGAACGGTTTTACTCTGTAAATCAAAGCCATAATCATTCCATTATTATCGG
TTCCAGTCTTTCTCACCAAGAGAATGATATCGAACACGATACCATACTCGATACATCAGGAGTGTTAGTG
ACTACTGATACAAATGGCATTGTTAACGGGGCAAGAGTCGCAATTACTGACGGTCTGGGTGGTGGAAATG
GCGATCAGGAAGAAGACGACGAGATATACAGAGTATCTCATTCCAGTTGCGCGAATTTTTTGAATTGCGA
CCAAAATATAGATACAACTCTAAGCTTGATTACCCAACCAAAGGCCTCTGATAAAAAACAAACAGCACCG
AAAACATTGCAGCATACAGAAGCGTCTATGGCTGCTTTTATTTATCAAAATCATCCGGGAAAAGGATACA
TAGGTGAATTTGCAAATATTGGTGATGGACTAATTATTATCCTGGATAAACGTTTTAAGATAAAGCATAT
GATATCCGCATGCCATATATATCGCGGATTTGGTACCTGGACTCCACCATCCCTGCAAGCCCTGGCAACA
ACTATAAATAAAGACGCCCTGCTTGTCAGACAAACACTTGAACTTGCAGAAGGCGACATTATAATATCAA
TGACGGATGGGGTTTGGGGGGAGCTGAAAACCAGTTTGATTGCTCAAACCAATGACCGTCGAGAGATAGG
AGTAGATAAAGAATATTTCAAAACGCTATTTGACGAATTGACAGATGCTCCCTACCCTTCTTCATTTGAT
ATTGCTCGTATCATTACCCATAGCGCCATGTCTCGCAGTTTGGAGCGTAGAAAAACGTTAATAAAATTAA
TTAATGAAATAGAACAACAACACTTCCATGAAAAATCTGTCAAAACCATTAATGAAATCCTGGAATATTT
TATTAAGACAGACCATGTGGAAACAGCACAGACATTAAAAGCAATTCTCTTTGAAGACGGTTTGAGTGAT
GGAGTAACTTATTTCGAAAATATTGAAATCCCGCTGGAGATGGTAATGCACGATTTAAAAAATCGTACCG
TCGGTGATTGTTCAACTATCAATGTAACGCGCATTCCCTATCATTTAGATGAGCTCATACGAGGTTTTAT
CAATTACCCTGAGAAACATCAAATCCTGGCGCCACTATTTAAAGCAAGGGTAAAGTCTGAGGCTGATTTA
GAAGAGGCATTTCATCGCTTGTCACTTGAAATGATACAACCTGAAATCGAGTGCCCAATTTCTGAAGCTC
ATTTTGAACGTGTTTTTAAAAAAGAAACCCTTGATAAAACTCAGGCTGTCTTAACTCACTATTTTCGTAT
TTCGACTGGTTTAGATAGTAAAAAAAATTATCAGGAACGATTAAATGATCTGAGTGCTTACTTATCAAAG
GAATCCTCTCTCGAAAAAAATGATATTAAATTGCTATTATCTATGCTAGATAGTGAAATAAAACCTAAAA
CCGGGGTTTTCCAAACATTATTTGGGGAAAACCAAAATAAATTATACAAGGCATTTCACAAAAAAATCGA
GTTGCAATTATTGGATGGTGAAATAGAAAATAAAAATGAATTGAAATAG

Reference
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] in_silico
 
in_silico in silico analysis literature