SecReT4
Effector Protein ID: 54293679
T4SS name [ID]Dot/Icm [41]
Gene symbol-
Locus taglpl0732
StrainLegionella pneumophila str. Lens
Repliconchromosome [GenBank: NC_006369] [Browse all T4SS(s) in this replicon]
Location [Strand]828401..831238 [+]
Producthypothetical protein
Effector typeProtein
DescriptonAnkN/ankX legA8
T4CP requirementT4CP Depedent
Target/EffectionAnkX modified both Rab1 and Rab35 by cAMP(Fic) domain-dependent manner (Mukherjee, et al, 2011)
UniProt IDQ5WYK4
KEGG IDlpf:lpl0732
PDB IDNA
Domain hit(s) vs Pfam Ank_2 [PF12796], Evalue: 1.1e-46, Aligned region: 368..438
Ank_2 [PF12796], Evalue: 1.1e-46, Aligned region: 441..523
Ank_2 [PF12796], Evalue: 1.1e-46, Aligned region: 557..627
Ank_2 [PF12796], Evalue: 1.1e-46, Aligned region: 642..710
Ank_4 [PF13637], Evalue: 1.1e-35, Aligned region: 390..436
Ank_4 [PF13637], Evalue: 1.1e-35, Aligned region: 618..675
Ank_5 [PF13857], Evalue: 3.2e-33, Aligned region: 382..428
Ank_5 [PF13857], Evalue: 3.2e-33, Aligned region: 584..624
Ank [PF00023], Evalue: 1.9e-31, Aligned region: 390..418
Ank [PF00023], Evalue: 1.9e-31, Aligned region: 420..437
Ank [PF00023], Evalue: 1.9e-31, Aligned region: 586..615
Fic [PF02661], Evalue: 1.5e-07, Aligned region: 173..234
Protein Sequence: 945 a.a.     [Download]
>gi|54293679|ref|YP_126094.1| hypothetical protein lpl0732 [Legionella pneumophila str. Lens]
MPNLPGLYFLQAYPREEIWRLFVDGRFWSKENGWRGYESREPGCLNAALESLCSIALQVEKSGEEFELSV
DLIKRIHKKCGKKVEELQEKNPGELRTDEPVSFGIPAGRASIKGIEEFLSLVFLTEGEAEFGPGKAGPFG
PRFDKNYFKNLNPEQIPDLAKQIYFDMCKYGHSNTNHFYLAVMKNVDVYLEKITQSYNQEIKTAETLDEK
LKIIVKHIRMYEVLHPFRDANGRTFVNNLLNILLMQQGLPPATFYEPNVFDLYSAEELVVVVKEAIFNTV
EIIEQSKKKTPITLYGYHSSLEEQTKFRDMLDSPSYEKIKHMDFSDLNPEKLHRKTQKCLSSLNEQYPLH
RGAIYLSDPGEIKLLLSNRNESQINQQIEQGAPPIYVDKTPAHLAVISGNMAMLDELIAKKADLSLQDYD
GKTALHYAAECGNMQIMGKILKVVLSQEDAIKVLNIKDNHGKTAFHYAAEFGTPELISALTTTEVIQINE
PDNSGSSAITLAYKNHKLKIFDELLNSGADISDELLDAIWARKDKETLGKIIAKNEKILLNKEAFRIAIS
LGSVSLVKKFLRAGVDIDIPLTKDKATPLMLSINSGNPKLVSYLLKKGANTRLTDTSGNSVLHYVFYSKA
ENREALANIITEKDKKLINQPNANGNSPLYNAVVVNDFKMATILLEMGARVDFEDRLGNNILHSAMRRCD
LPIILDIVKKDSTLLHKRNSERRNPFHQALHEMHTFPSSKETEEIHFMNLSDLLLKEGVDLNKKDIKGKT
ILDIALSKQYFHLCVKLMKAGAHTNISSPSKFLKNSDANSILERPFKFKNDLKKELDDNPLIAMTQINDL
YVQIKNNRIRTPTGYAPKEGVSFFKGKSNDAKAHDEVLSVLKELYDSKLTEMLGNLPGEGLEEIKRSQKF
FDGELKLLIKNQDISRKVDKKSIQEAVGTSLKLKW
-
Nucleotide Sequence: 2838 bp     [Download]
>gi|54292964|ref|NC_006369.1|:828401-831238 Legionella pneumophila str. Lens, complete genome
ATGCCGAATCTACCTGGATTATATTTTCTTCAAGCCTATCCACGCGAAGAAATATGGAGATTATTTGTTG
ATGGGCGCTTCTGGTCAAAAGAAAATGGATGGAGAGGCTATGAGTCGCGAGAGCCAGGATGCCTTAACGC
CGCTCTGGAGAGTTTATGTTCTATTGCATTGCAAGTTGAGAAATCAGGTGAGGAATTTGAATTAAGCGTT
GATTTAATAAAAAGGATTCACAAGAAGTGTGGAAAAAAGGTGGAGGAATTACAGGAAAAAAATCCAGGTG
AACTCAGAACAGATGAACCTGTTTCATTTGGCATTCCAGCTGGCCGGGCCTCGATTAAGGGTATTGAAGA
ATTCCTGAGCCTGGTATTTCTTACAGAAGGCGAAGCTGAATTTGGCCCAGGCAAAGCGGGTCCATTTGGC
CCACGCTTTGATAAGAACTATTTTAAAAATCTGAATCCAGAACAAATACCTGATCTTGCTAAGCAAATCT
ATTTCGATATGTGCAAATATGGGCATAGTAATACTAATCACTTTTATCTTGCAGTAATGAAAAATGTGGA
TGTTTACCTGGAAAAAATTACCCAATCTTACAACCAGGAAATAAAAACCGCCGAAACTCTTGATGAAAAA
CTTAAAATTATCGTTAAGCATATTCGAATGTACGAAGTATTACACCCTTTTCGAGATGCCAATGGCCGTA
CCTTTGTCAATAATTTATTAAATATTCTTTTAATGCAACAAGGTTTACCGCCAGCGACGTTTTACGAACC
TAATGTCTTTGATTTATATAGCGCTGAGGAATTAGTTGTTGTTGTGAAGGAAGCAATTTTTAATACGGTA
GAAATTATTGAACAAAGTAAAAAAAAGACTCCCATTACTTTATATGGATACCATTCAAGCTTGGAAGAGC
AAACCAAATTTCGGGATATGCTGGATAGTCCATCGTATGAAAAAATCAAACATATGGATTTTTCAGATTT
AAACCCTGAGAAACTGCATCGGAAGACTCAAAAATGTTTATCATCACTAAATGAGCAATATCCATTACAC
AGAGGCGCAATCTATCTTAGTGATCCCGGTGAGATAAAATTATTATTGTCAAATCGCAATGAATCCCAGA
TTAATCAGCAGATAGAGCAAGGAGCACCGCCTATTTATGTCGATAAAACTCCTGCTCATTTGGCTGTCAT
ATCAGGAAATATGGCGATGCTTGATGAGCTTATTGCAAAAAAAGCGGATTTATCTCTTCAGGATTATGAT
GGAAAAACTGCTCTTCACTATGCTGCAGAGTGTGGAAATATGCAAATTATGGGAAAAATACTAAAAGTTG
TGCTAAGCCAGGAAGATGCCATCAAAGTGCTGAATATCAAGGATAATCATGGCAAAACAGCATTCCATTA
TGCTGCTGAGTTTGGAACCCCGGAATTAATATCAGCCTTGACAACCACAGAGGTTATTCAGATTAATGAA
CCGGATAACAGCGGTTCTTCAGCAATCACTTTGGCATATAAAAATCATAAATTGAAAATTTTCGATGAAC
TATTAAACTCCGGTGCTGATATCAGTGATGAGCTTTTGGACGCGATATGGGCTCGGAAGGATAAAGAAAC
ATTAGGTAAAATAATTGCTAAAAATGAGAAAATTCTTTTGAATAAAGAAGCCTTCAGGATAGCTATTTCT
TTAGGAAGTGTCAGTCTGGTTAAAAAATTTTTACGTGCCGGGGTCGATATTGATATACCCTTAACCAAAG
ATAAAGCAACACCGCTAATGTTATCTATAAATTCCGGTAATCCCAAATTGGTCAGTTATTTATTGAAAAA
GGGAGCTAATACACGTTTAACTGATACCAGTGGTAATTCTGTCCTGCATTATGTTTTTTATTCAAAGGCA
GAAAACAGGGAAGCTTTAGCAAATATTATAACTGAGAAAGATAAGAAATTAATTAATCAGCCAAATGCTA
ATGGAAATTCACCTCTTTATAATGCTGTGGTAGTTAATGATTTCAAAATGGCAACAATTTTATTAGAAAT
GGGGGCAAGGGTCGATTTTGAAGACAGGCTGGGAAATAATATTTTGCATAGTGCCATGAGAAGATGTGAT
TTGCCGATTATATTGGATATTGTCAAGAAAGATAGCACCTTACTTCATAAAAGAAACTCTGAAAGAAGAA
ATCCTTTTCATCAGGCATTGCATGAGATGCATACTTTTCCATCCTCAAAAGAAACCGAAGAAATACACTT
CATGAATTTAAGTGATTTACTTTTAAAAGAAGGAGTCGATTTAAATAAAAAAGATATTAAAGGAAAAACA
ATATTAGATATCGCATTATCCAAGCAGTATTTTCATTTATGTGTCAAACTGATGAAAGCAGGTGCTCATA
CCAATATATCTTCTCCATCAAAATTTCTTAAAAACTCCGATGCCAATTCTATTTTGGAACGTCCTTTTAA
ATTTAAGAACGATTTAAAAAAAGAGCTCGATGATAATCCGCTAATTGCTATGACACAAATTAATGATTTG
TACGTCCAAATCAAAAATAACAGGATTAGGACTCCTACAGGTTATGCCCCGAAAGAAGGAGTATCCTTTT
TTAAAGGAAAATCAAACGATGCCAAAGCACATGATGAGGTTTTATCTGTTTTAAAGGAACTCTACGATAG
TAAACTCACAGAGATGCTCGGTAACCTTCCTGGCGAAGGATTAGAAGAAATCAAAAGAAGCCAGAAATTT
TTTGACGGCGAGCTAAAATTATTAATTAAAAACCAGGACATTTCGAGGAAAGTCGATAAAAAGTCTATTC
AGGAAGCAGTTGGTACATCCTTGAAATTAAAATGGTAA

Reference
(1) Rolando M; Buchrieser C (2012). Post-translational modifications of host proteins by Legionella pneumophila: a sophisticated survival strategy. Future Microbiol. 7(3):369-81. [PudMed:22393890]
(2) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] in_silico
 
in_silico in silico analysis literature