| Effector Protein ID: 54293679 |
 T4SS name [ID] | Dot/Icm [41] |
| Gene symbol | - |
| Locus tag | lpl0732 |
| Strain | Legionella pneumophila str. Lens |
| Replicon | chromosome [GenBank: NC_006369] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 828401..831238 [+] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | AnkN/ankX legA8 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | AnkX modified both Rab1 and Rab35 by cAMP(Fic) domain-dependent manner (Mukherjee, et al, 2011) |
| UniProt ID | Q5WYK4 |
| KEGG ID | lpf:lpl0732 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | Ank_2 [PF12796], Evalue: 1.1e-46, Aligned region: 368..438 Ank_2 [PF12796], Evalue: 1.1e-46, Aligned region: 441..523 Ank_2 [PF12796], Evalue: 1.1e-46, Aligned region: 557..627 Ank_2 [PF12796], Evalue: 1.1e-46, Aligned region: 642..710 Ank_4 [PF13637], Evalue: 1.1e-35, Aligned region: 390..436 Ank_4 [PF13637], Evalue: 1.1e-35, Aligned region: 618..675 Ank_5 [PF13857], Evalue: 3.2e-33, Aligned region: 382..428 Ank_5 [PF13857], Evalue: 3.2e-33, Aligned region: 584..624 Ank [PF00023], Evalue: 1.9e-31, Aligned region: 390..418 Ank [PF00023], Evalue: 1.9e-31, Aligned region: 420..437 Ank [PF00023], Evalue: 1.9e-31, Aligned region: 586..615 Fic [PF02661], Evalue: 1.5e-07, Aligned region: 173..234 |
| Protein Sequence: 945 a.a. [Download] |
| >gi|54293679|ref|YP_126094.1| hypothetical protein lpl0732 [Legionella pneumophila str. Lens] MPNLPGLYFLQAYPREEIWRLFVDGRFWSKENGWRGYESREPGCLNAALESLCSIALQVEKSGEEFELSV DLIKRIHKKCGKKVEELQEKNPGELRTDEPVSFGIPAGRASIKGIEEFLSLVFLTEGEAEFGPGKAGPFG PRFDKNYFKNLNPEQIPDLAKQIYFDMCKYGHSNTNHFYLAVMKNVDVYLEKITQSYNQEIKTAETLDEK LKIIVKHIRMYEVLHPFRDANGRTFVNNLLNILLMQQGLPPATFYEPNVFDLYSAEELVVVVKEAIFNTV EIIEQSKKKTPITLYGYHSSLEEQTKFRDMLDSPSYEKIKHMDFSDLNPEKLHRKTQKCLSSLNEQYPLH RGAIYLSDPGEIKLLLSNRNESQINQQIEQGAPPIYVDKTPAHLAVISGNMAMLDELIAKKADLSLQDYD GKTALHYAAECGNMQIMGKILKVVLSQEDAIKVLNIKDNHGKTAFHYAAEFGTPELISALTTTEVIQINE PDNSGSSAITLAYKNHKLKIFDELLNSGADISDELLDAIWARKDKETLGKIIAKNEKILLNKEAFRIAIS LGSVSLVKKFLRAGVDIDIPLTKDKATPLMLSINSGNPKLVSYLLKKGANTRLTDTSGNSVLHYVFYSKA ENREALANIITEKDKKLINQPNANGNSPLYNAVVVNDFKMATILLEMGARVDFEDRLGNNILHSAMRRCD LPIILDIVKKDSTLLHKRNSERRNPFHQALHEMHTFPSSKETEEIHFMNLSDLLLKEGVDLNKKDIKGKT ILDIALSKQYFHLCVKLMKAGAHTNISSPSKFLKNSDANSILERPFKFKNDLKKELDDNPLIAMTQINDL YVQIKNNRIRTPTGYAPKEGVSFFKGKSNDAKAHDEVLSVLKELYDSKLTEMLGNLPGEGLEEIKRSQKF FDGELKLLIKNQDISRKVDKKSIQEAVGTSLKLKW |
| - |
| Nucleotide Sequence: 2838 bp [Download] |
| >gi|54292964|ref|NC_006369.1|:828401-831238 Legionella pneumophila str. Lens, complete genome ATGCCGAATCTACCTGGATTATATTTTCTTCAAGCCTATCCACGCGAAGAAATATGGAGATTATTTGTTG ATGGGCGCTTCTGGTCAAAAGAAAATGGATGGAGAGGCTATGAGTCGCGAGAGCCAGGATGCCTTAACGC CGCTCTGGAGAGTTTATGTTCTATTGCATTGCAAGTTGAGAAATCAGGTGAGGAATTTGAATTAAGCGTT GATTTAATAAAAAGGATTCACAAGAAGTGTGGAAAAAAGGTGGAGGAATTACAGGAAAAAAATCCAGGTG AACTCAGAACAGATGAACCTGTTTCATTTGGCATTCCAGCTGGCCGGGCCTCGATTAAGGGTATTGAAGA ATTCCTGAGCCTGGTATTTCTTACAGAAGGCGAAGCTGAATTTGGCCCAGGCAAAGCGGGTCCATTTGGC CCACGCTTTGATAAGAACTATTTTAAAAATCTGAATCCAGAACAAATACCTGATCTTGCTAAGCAAATCT ATTTCGATATGTGCAAATATGGGCATAGTAATACTAATCACTTTTATCTTGCAGTAATGAAAAATGTGGA TGTTTACCTGGAAAAAATTACCCAATCTTACAACCAGGAAATAAAAACCGCCGAAACTCTTGATGAAAAA CTTAAAATTATCGTTAAGCATATTCGAATGTACGAAGTATTACACCCTTTTCGAGATGCCAATGGCCGTA CCTTTGTCAATAATTTATTAAATATTCTTTTAATGCAACAAGGTTTACCGCCAGCGACGTTTTACGAACC TAATGTCTTTGATTTATATAGCGCTGAGGAATTAGTTGTTGTTGTGAAGGAAGCAATTTTTAATACGGTA GAAATTATTGAACAAAGTAAAAAAAAGACTCCCATTACTTTATATGGATACCATTCAAGCTTGGAAGAGC AAACCAAATTTCGGGATATGCTGGATAGTCCATCGTATGAAAAAATCAAACATATGGATTTTTCAGATTT AAACCCTGAGAAACTGCATCGGAAGACTCAAAAATGTTTATCATCACTAAATGAGCAATATCCATTACAC AGAGGCGCAATCTATCTTAGTGATCCCGGTGAGATAAAATTATTATTGTCAAATCGCAATGAATCCCAGA TTAATCAGCAGATAGAGCAAGGAGCACCGCCTATTTATGTCGATAAAACTCCTGCTCATTTGGCTGTCAT ATCAGGAAATATGGCGATGCTTGATGAGCTTATTGCAAAAAAAGCGGATTTATCTCTTCAGGATTATGAT GGAAAAACTGCTCTTCACTATGCTGCAGAGTGTGGAAATATGCAAATTATGGGAAAAATACTAAAAGTTG TGCTAAGCCAGGAAGATGCCATCAAAGTGCTGAATATCAAGGATAATCATGGCAAAACAGCATTCCATTA TGCTGCTGAGTTTGGAACCCCGGAATTAATATCAGCCTTGACAACCACAGAGGTTATTCAGATTAATGAA CCGGATAACAGCGGTTCTTCAGCAATCACTTTGGCATATAAAAATCATAAATTGAAAATTTTCGATGAAC TATTAAACTCCGGTGCTGATATCAGTGATGAGCTTTTGGACGCGATATGGGCTCGGAAGGATAAAGAAAC ATTAGGTAAAATAATTGCTAAAAATGAGAAAATTCTTTTGAATAAAGAAGCCTTCAGGATAGCTATTTCT TTAGGAAGTGTCAGTCTGGTTAAAAAATTTTTACGTGCCGGGGTCGATATTGATATACCCTTAACCAAAG ATAAAGCAACACCGCTAATGTTATCTATAAATTCCGGTAATCCCAAATTGGTCAGTTATTTATTGAAAAA GGGAGCTAATACACGTTTAACTGATACCAGTGGTAATTCTGTCCTGCATTATGTTTTTTATTCAAAGGCA GAAAACAGGGAAGCTTTAGCAAATATTATAACTGAGAAAGATAAGAAATTAATTAATCAGCCAAATGCTA ATGGAAATTCACCTCTTTATAATGCTGTGGTAGTTAATGATTTCAAAATGGCAACAATTTTATTAGAAAT GGGGGCAAGGGTCGATTTTGAAGACAGGCTGGGAAATAATATTTTGCATAGTGCCATGAGAAGATGTGAT TTGCCGATTATATTGGATATTGTCAAGAAAGATAGCACCTTACTTCATAAAAGAAACTCTGAAAGAAGAA ATCCTTTTCATCAGGCATTGCATGAGATGCATACTTTTCCATCCTCAAAAGAAACCGAAGAAATACACTT CATGAATTTAAGTGATTTACTTTTAAAAGAAGGAGTCGATTTAAATAAAAAAGATATTAAAGGAAAAACA ATATTAGATATCGCATTATCCAAGCAGTATTTTCATTTATGTGTCAAACTGATGAAAGCAGGTGCTCATA CCAATATATCTTCTCCATCAAAATTTCTTAAAAACTCCGATGCCAATTCTATTTTGGAACGTCCTTTTAA ATTTAAGAACGATTTAAAAAAAGAGCTCGATGATAATCCGCTAATTGCTATGACACAAATTAATGATTTG TACGTCCAAATCAAAAATAACAGGATTAGGACTCCTACAGGTTATGCCCCGAAAGAAGGAGTATCCTTTT TTAAAGGAAAATCAAACGATGCCAAAGCACATGATGAGGTTTTATCTGTTTTAAAGGAACTCTACGATAG TAAACTCACAGAGATGCTCGGTAACCTTCCTGGCGAAGGATTAGAAGAAATCAAAAGAAGCCAGAAATTT TTTGACGGCGAGCTAAAATTATTAATTAAAAACCAGGACATTTCGAGGAAAGTCGATAAAAAGTCTATTC AGGAAGCAGTTGGTACATCCTTGAAATTAAAATGGTAA |
| Reference |
| (1) Rolando M; Buchrieser C (2012). Post-translational modifications of host proteins by Legionella pneumophila: a sophisticated survival strategy. Future Microbiol. 7(3):369-81. [PudMed:22393890] |
(2) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
|
| in silico analysis literature |