| Effector Protein ID: 54293280 |
 T4SS name [ID] | Dot/Icm [41] |
| Gene symbol | - |
| Locus tag | lpl0328 |
| Strain | Legionella pneumophila str. Lens |
| Replicon | chromosome [GenBank: NC_006369] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 376263..377702 [+] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | LegG2 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | LegG2, which has a Ras GEF domain, is believed to be involved in GDP-to-GTP exchange in Ras GTP-binding protein (de Felipe, et al. 2005) |
| UniProt ID | Q5WZQ3 |
| KEGG ID | lpf:lpl0328 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | RasGEF [PF00617], Evalue: 1.7e-08, Aligned region: 57..213 |
| Protein Sequence: 479 a.a. [Download] |
| >gi|54293280|ref|YP_125695.1| hypothetical protein lpl0328 [Legionella pneumophila str. Lens] MPKILDSNAYREMENELNNLFEQIYKHGKNDRTAITLQAQQFLDNLSESIRDHSRLLLTKIAREELIYFK VKIPGDSREKFQNIDKMSDYFNNLSVLINFSVMQQEDPTLRVFYYDMYIQLMNFCYLKGDLFGASAIYTG LISNNLPNSIDRKQLSSESRLIFKDCEEKFKRLFNRSTTYNDHTNLKRQFKTAFIPALPALFTVQIYTKD PYDNSVSDFERIQEKLRRLDIEHNRFLNQLQNDHSTWSKAYYDYMSNVYLPQSIFEYKTLLREYEKLVTT HGGPIAKQFHKDKNSEPLVNFVESMLSENQSVLKVSPFQNERIVEMLSEIDVVKSECSSPAVFDDLFWKL RDMNCTLVKAKSIGDYTSKIFANLDTPYMEENTDEDPKPVLVEELQTDDVYQLHHSGMKLMRELEQAIED HKPKITYRCSGEANYGFFSEARRRGRHLSPEPMDIEVMDVDVMDYDENDLRDQTVMITV |
| - |
| Nucleotide Sequence: 1440 bp [Download] |
| >gi|54292964|ref|NC_006369.1|:376263-377702 Legionella pneumophila str. Lens, complete genome ATGCCTAAAATTTTAGATAGCAATGCATACCGCGAGATGGAAAATGAGCTCAATAATCTTTTTGAGCAAA TTTATAAGCATGGTAAAAATGACAGAACCGCGATTACATTACAAGCTCAGCAATTTTTAGATAATTTGAG TGAATCCATAAGGGATCATTCCCGCTTATTGCTTACCAAAATTGCCAGAGAAGAACTCATTTATTTTAAG GTAAAAATACCTGGGGATTCGCGAGAGAAATTTCAAAATATCGATAAGATGAGTGATTACTTTAACAATT TATCTGTATTGATTAATTTCTCGGTGATGCAGCAAGAAGATCCTACTCTGCGGGTTTTTTATTATGATAT GTATATTCAACTAATGAATTTTTGCTATCTTAAAGGAGATTTGTTTGGAGCAAGTGCAATATATACAGGA TTAATATCCAATAACCTCCCTAACTCTATTGATCGGAAGCAATTGAGTTCCGAGAGTCGCTTGATTTTTA AAGATTGTGAAGAAAAATTTAAGCGATTATTTAATCGCTCAACGACATACAATGATCACACTAATTTAAA AAGACAATTCAAAACCGCCTTTATACCCGCATTACCAGCGCTTTTCACGGTTCAGATATATACTAAAGAC CCTTACGATAACTCTGTCAGCGATTTTGAAAGAATTCAGGAGAAGTTACGTCGGTTGGATATAGAACATA ATCGGTTTCTTAATCAATTACAGAATGACCATTCAACCTGGTCTAAAGCTTATTATGATTATATGAGTAA TGTTTATCTCCCGCAAAGCATATTCGAATACAAGACTCTCTTAAGAGAGTATGAAAAACTTGTCACAACG CATGGTGGCCCTATTGCGAAGCAGTTTCATAAGGATAAGAATTCAGAACCTCTGGTAAATTTTGTTGAAT CGATGCTATCAGAAAATCAATCAGTTCTCAAAGTATCTCCTTTTCAAAATGAGAGAATTGTTGAAATGCT TTCCGAGATTGACGTGGTAAAAAGTGAGTGCTCAAGCCCAGCTGTGTTTGATGACCTCTTCTGGAAGTTG AGAGACATGAATTGTACCTTGGTAAAAGCTAAATCTATTGGTGATTATACTTCCAAAATTTTTGCAAATC TTGATACTCCATACATGGAAGAAAATACGGATGAAGATCCGAAACCAGTGCTTGTAGAAGAACTGCAAAC GGATGATGTGTACCAACTTCACCATAGTGGTATGAAATTGATGCGTGAGCTCGAACAGGCTATAGAAGAT CATAAACCGAAAATTACTTATCGTTGTTCAGGTGAGGCAAACTATGGTTTCTTTAGTGAAGCCAGGAGGA GAGGGAGACATTTGAGTCCAGAACCAATGGATATCGAAGTCATGGATGTGGATGTTATGGATTATGATGA GAATGATTTACGTGATCAAACCGTTATGATTACGGTGTAA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| in silico analysis literature |