SecReT4
Effector Protein ID: 54293240
T4SS name [ID]Dot/Icm [41]
Gene symbolsidE
Locus taglpl0288
StrainLegionella pneumophila str. Lens
Repliconchromosome [GenBank: NC_006369] [Browse all T4SS(s) in this replicon]
Location [Strand]322701..327188 [-]
ProductSidE protein, substrate of the Dot/Icm system
Effector typeProtein
DescriptonSidE/laiD
T4CP requirementT4CP Depedent
Target/EffectionUnknown
UniProt IDQ5WZU3
KEGG IDlpf:lpl0288
PDB IDNA
Domain hit(s) vs Pfam SidE [PF12252], Evalue: 0, Aligned region: 1..1436
Protein Sequence: 1495 a.a.     [Download]
>gi|54293240|ref|YP_125655.1| SidE protein, substrate of the Dot/Icm system [Legionella pneumophila str. Lens]
MPKYVEGIELTQEGMHAIFERMGHPNITSGTIYNGEPTIDKGALDRQGFMPVLTGVSPRQDSGHWIMLIK
GQGNQYFLFDPLGESSGKYYQNILAKKLPGATLSVIPNNAGLNMGLCGYWVASVGLRAHAALTQPIPPSL
RNVGQTITQEMRDELTQDGSEKITQWLRAVGNEFPDGDIQPDATALRRATEKNVRIDEFQPVLTGTSPKE
ISINPTAPQEVSVPTWNGFSLYTDETVRNAARYAYDNYLGKPYTGTVEATPVNFGGQMVYRQHHGLAHTL
RTMAYAEIIVEEARKAKLRGESLKTFADGRTLADVTPEELRKIMIAQAFFVTGRDDEESSKNYEKYHEQS
RDAFLKYVEENKSTLIPDVFKDEKDVKFYADVIEDKDHKWADSPAHVLVNQGHMVDLVRVKQPPESYLEY
YFSQLQPWIGSTATEAVFATQRQFFHATYEAVAGFDSENKEPHLVVDGLGRYVIGQDGNPIREESDDEDE
EESGELKFFSQKKKLEENQRYMRVDEYLKLDEVQKRFPGAGKKLDGGLPGLKEYQYLQRLNSINRARCEN
DVDFCLGQLQTAHHQTKITPIKRAFQSSSDKVRRQPNMDEIAAARIIQQIMANPDCIHDDHVLLNGQKLE
EKFFRNLLAKCDMAIVGSLLNDTDIRNIDTLMQHERNTEFHSTDAKAKPVKLGETWEKTIRSGGGVTQIK
HDLIFLMQNDAWYHTRVNAIAQNRDKDSTFKEVLITALMTPLTNKSLIDTSRSPAPKTLFRGLDLSEEFK
NKLINQAETIIANTTEHLFTDLSTEAFKQIKLNDFSQVSARTCASTSTNIEVPRTIFGSNTIFEILDPDG
LLHPKQVGTHVSGSESEYSIYLPEDVALVPIKVSFDGKTGKGKDRHIFTLVAVKSPDFTPKHESGYAVEP
LLKMQTPKLEEVQRLVEQAREEPDLERVFNLQSRVARQARFSTESGYKTFLNEKVAPVLEQSLNGLLDNN
VTILGKALSAFPSDGQWSAFNSVEARQMKIQMDAIKQMVEKKAVLEGQILPALAQCQNALEKQNIAGALQ
ALRNIPSEKEMQTMLSISGGLRGQIQRTKQDLTETLEPLQRAITSKLVSDQEKVNVRYEKLIASIPQRIA
DLEKAALSDLAGVKKVVSHFNQLQEELKLLRNEKIRMHTGSEKIDFSDIAQLEAQLQKIHTKLYDAYLVE
LTKEISALVKEKPKNLADVKRMVSNFYAMSADIEQLRQEKIKEHGESKDPIDMSDIDKLKEELQKINQFL
VKAMGTNIRVSLNQMEVKTFDAQEKEAQQNLKQLDELINKLESSHAVQKQKEELEKLNQLLVEKRKAYPA
MVQLQFRSEALIIHLRELCEAHQAQMAKTRNVRAQEITNGRWKVQWLTDWVGLTTDERVTLANKEKELAK
FKEDLNNDEYDLQELISNLAEKNPSELEEAIGISKESAQKLHKLLTHLNHSTTFMNKIDQRLQSIDELLN
EFGKQSPRTEMIKTVEEKQGTLLRL
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Nucleotide Sequence: 4488 bp     [Download]
>gi|54292964|ref|NC_006369.1|:c327188-322701 Legionella pneumophila str. Lens, complete genome
ATGCCTAAGTACGTTGAAGGGATAGAATTAACCCAAGAAGGGATGCATGCTATTTTTGAACGCATGGGAC
ATCCAAATATTACCAGCGGTACTATCTACAACGGAGAGCCTACAATTGATAAAGGTGCTCTTGACAGGCA
AGGCTTTATGCCAGTATTGACCGGGGTCAGCCCAAGGCAAGACTCGGGACATTGGATTATGTTAATTAAA
GGTCAAGGCAATCAATATTTCCTCTTTGACCCGCTGGGAGAAAGCTCGGGAAAATATTACCAAAATATTT
TAGCTAAAAAACTACCTGGCGCTACACTTTCTGTTATTCCTAATAATGCTGGATTAAATATGGGATTATG
CGGCTATTGGGTTGCCTCAGTTGGTTTAAGAGCTCATGCGGCTTTAACACAACCTATTCCCCCTTCTTTA
AGAAATGTGGGTCAAACCATTACCCAGGAAATGCGAGATGAACTAACACAAGATGGAAGCGAAAAAATTA
CACAATGGTTACGGGCCGTTGGCAATGAATTTCCAGATGGTGATATACAACCTGATGCCACAGCCTTAAG
ACGTGCTACTGAAAAGAATGTACGTATTGATGAGTTTCAGCCTGTTTTAACTGGAACATCACCTAAAGAA
ATTTCGATAAATCCTACTGCTCCTCAAGAAGTATCCGTTCCCACGTGGAATGGTTTTTCCTTATATACTG
ATGAAACCGTGAGAAATGCAGCAAGATACGCGTATGATAATTACTTGGGAAAACCTTATACCGGTACAGT
AGAAGCGACACCTGTCAATTTTGGTGGGCAAATGGTATACAGGCAACACCATGGTCTTGCCCACACATTG
CGCACCATGGCCTATGCGGAAATCATTGTTGAGGAAGCGCGAAAAGCAAAATTAAGGGGTGAATCATTAA
AAACATTTGCTGATGGTCGTACTCTGGCGGATGTTACGCCTGAAGAATTGAGAAAAATCATGATCGCCCA
GGCCTTCTTTGTCACTGGAAGAGACGATGAAGAATCCTCCAAGAATTATGAAAAATACCACGAACAAAGC
CGAGATGCTTTTTTGAAATATGTCGAAGAGAATAAATCCACTTTAATTCCCGATGTATTCAAAGATGAAA
AAGATGTCAAATTCTATGCTGATGTCATTGAAGATAAAGATCATAAATGGGCAGATTCACCGGCGCATGT
CCTGGTCAATCAGGGCCATATGGTTGATTTGGTCAGAGTAAAACAACCCCCTGAATCTTACCTGGAATAC
TATTTTTCACAACTTCAACCCTGGATAGGTTCAACAGCTACGGAAGCAGTTTTTGCGACACAGAGACAAT
TCTTCCATGCCACCTATGAAGCAGTTGCGGGCTTTGATAGCGAAAACAAAGAACCTCATCTGGTGGTCGA
TGGTTTAGGTCGCTATGTGATTGGACAAGATGGCAATCCAATACGCGAAGAATCTGATGACGAAGACGAG
GAAGAATCAGGTGAATTAAAATTTTTCTCACAAAAAAAGAAACTCGAGGAAAACCAACGTTACATGCGCG
TTGATGAATATTTAAAACTTGATGAGGTCCAAAAGCGATTCCCTGGCGCTGGTAAAAAACTCGATGGGGG
GCTGCCTGGACTGAAAGAATATCAATATTTACAACGCTTGAACTCAATAAACAGAGCACGGTGTGAAAAC
GACGTCGACTTTTGTTTGGGACAATTACAAACGGCACATCATCAAACCAAAATTACTCCAATAAAAAGAG
CCTTCCAATCCAGCTCTGATAAAGTGAGAAGACAACCCAATATGGATGAAATTGCTGCTGCCCGTATTAT
TCAGCAAATCATGGCCAATCCTGATTGCATCCATGACGATCATGTGCTGCTCAATGGTCAAAAACTGGAA
GAAAAATTTTTCCGTAATTTGTTGGCGAAATGTGACATGGCTATTGTAGGGTCGCTATTAAACGATACAG
ACATTAGAAATATCGACACCTTAATGCAACATGAGAGAAACACAGAATTTCACTCAACAGATGCCAAAGC
AAAACCGGTGAAACTGGGAGAAACATGGGAAAAAACAATCAGATCGGGTGGTGGGGTTACTCAGATAAAA
CATGATTTAATTTTCCTCATGCAAAATGATGCCTGGTACCATACTCGAGTCAATGCGATTGCGCAAAACC
GGGATAAAGATTCAACATTCAAAGAAGTGTTGATTACCGCTTTAATGACACCATTGACTAACAAATCATT
GATAGATACATCACGTTCCCCGGCCCCAAAAACGCTATTCCGTGGCTTGGATCTGTCAGAAGAGTTTAAA
AATAAATTAATTAACCAGGCTGAAACCATCATTGCCAATACGACAGAACATCTCTTTACTGATCTGTCGA
CAGAAGCCTTTAAACAAATTAAATTAAATGACTTTAGCCAGGTTTCTGCTAGAACTTGTGCCAGTACTTC
CACTAACATTGAAGTTCCCAGGACAATCTTTGGCTCCAATACCATCTTTGAAATACTTGATCCCGATGGT
TTATTACACCCCAAACAAGTTGGAACCCATGTATCAGGGTCAGAAAGTGAATATTCCATTTATTTGCCGG
AAGATGTTGCCTTGGTTCCAATCAAAGTAAGCTTTGATGGAAAAACAGGTAAAGGCAAAGACCGACATAT
TTTTACTTTAGTCGCGGTAAAAAGCCCTGATTTCACGCCAAAGCATGAAAGTGGTTATGCTGTTGAACCT
CTTTTGAAAATGCAAACGCCAAAATTAGAAGAAGTTCAAAGATTAGTTGAGCAAGCAAGGGAAGAACCTG
ACCTGGAAAGGGTATTCAATTTACAATCGAGAGTAGCAAGACAAGCCAGATTCTCCACTGAATCAGGATA
TAAAACGTTTCTGAATGAAAAGGTGGCGCCTGTGTTGGAACAAAGCCTCAATGGCCTCTTGGACAATAAT
GTAACCATTCTAGGCAAAGCATTATCAGCATTCCCTTCAGACGGCCAATGGTCTGCCTTTAATTCAGTTG
AAGCAAGGCAAATGAAAATACAGATGGATGCCATTAAGCAAATGGTTGAAAAGAAAGCCGTCCTCGAAGG
TCAAATTCTCCCTGCCTTGGCTCAATGCCAGAATGCTTTGGAGAAACAAAATATTGCAGGTGCATTACAA
GCACTTAGAAACATCCCTTCTGAAAAAGAAATGCAAACCATGCTGTCAATTAGTGGTGGTTTGAGAGGAC
AAATCCAGCGTACCAAGCAAGATTTGACTGAAACTCTGGAACCACTTCAACGCGCCATAACTTCTAAATT
GGTAAGCGATCAAGAAAAAGTGAACGTGCGTTATGAAAAGCTGATAGCAAGCATACCTCAACGGATCGCC
GATCTTGAAAAAGCTGCGCTTTCTGATCTTGCCGGTGTTAAAAAAGTTGTCTCTCATTTTAATCAGCTGC
AAGAAGAATTAAAGTTGCTGCGTAATGAAAAAATTCGAATGCACACTGGCTCTGAAAAAATTGATTTTTC
AGATATCGCACAATTAGAGGCGCAACTACAAAAAATCCATACTAAATTATATGACGCCTATTTGGTTGAA
TTAACTAAAGAAATTTCAGCACTGGTTAAAGAAAAACCGAAAAACCTGGCCGACGTGAAAAGGATGGTTT
CGAATTTCTATGCTATGTCAGCTGATATTGAACAATTGCGTCAGGAAAAGATAAAAGAACACGGTGAGTC
AAAAGATCCGATTGATATGTCTGATATTGATAAATTAAAGGAAGAACTACAAAAAATTAATCAATTTTTA
GTGAAGGCGATGGGAACTAATATCAGGGTTTCACTGAATCAAATGGAAGTAAAAACTTTTGATGCCCAGG
AAAAGGAAGCACAACAAAATTTGAAGCAATTAGACGAACTGATTAATAAATTGGAAAGTTCTCATGCTGT
ACAGAAACAAAAAGAAGAACTCGAAAAATTAAACCAATTGCTTGTCGAGAAGCGCAAAGCCTATCCCGCA
ATGGTGCAGTTGCAATTCAGGAGTGAAGCATTAATTATCCATTTACGTGAATTATGTGAAGCTCATCAAG
CTCAAATGGCTAAAACAAGAAATGTAAGGGCGCAAGAAATCACTAATGGACGATGGAAAGTACAATGGTT
GACTGATTGGGTTGGTTTAACTACAGATGAGCGGGTAACTCTTGCCAACAAAGAAAAAGAATTGGCTAAA
TTCAAGGAAGATTTAAATAATGACGAGTATGATTTGCAGGAACTCATCAGTAACCTGGCTGAGAAAAACC
CGTCAGAATTGGAAGAAGCCATAGGGATATCTAAAGAGAGCGCTCAGAAATTGCATAAACTGTTAACTCA
TCTAAACCACAGTACAACATTTATGAATAAAATCGACCAACGATTACAGTCTATTGATGAGCTATTAAAC
GAGTTTGGCAAGCAATCGCCCCGAACTGAAATGATAAAAACTGTTGAGGAAAAACAAGGAACTCTCTTAA
GATTGTAA

Reference
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] in_silico
 
in_silico in silico analysis literature