Effector Protein ID: 54293240 |
T4SS name [ID] | Dot/Icm [41] |
Gene symbol | sidE |
Locus tag | lpl0288 |
Strain | Legionella pneumophila str. Lens |
Replicon | chromosome [GenBank: NC_006369] [Browse all T4SS(s) in this replicon] |
Location [Strand] | 322701..327188 [-] |
Product | SidE protein, substrate of the Dot/Icm system |
Effector type | Protein |
Descripton | SidE/laiD |
T4CP requirement | T4CP Depedent |
Target/Effection | Unknown |
UniProt ID | Q5WZU3 |
KEGG ID | lpf:lpl0288 |
PDB ID | NA |
Domain hit(s) vs Pfam | SidE [PF12252], Evalue: 0, Aligned region: 1..1436 |
Protein Sequence: 1495 a.a. [Download] |
>gi|54293240|ref|YP_125655.1| SidE protein, substrate of the Dot/Icm system [Legionella pneumophila str. Lens] MPKYVEGIELTQEGMHAIFERMGHPNITSGTIYNGEPTIDKGALDRQGFMPVLTGVSPRQDSGHWIMLIK GQGNQYFLFDPLGESSGKYYQNILAKKLPGATLSVIPNNAGLNMGLCGYWVASVGLRAHAALTQPIPPSL RNVGQTITQEMRDELTQDGSEKITQWLRAVGNEFPDGDIQPDATALRRATEKNVRIDEFQPVLTGTSPKE ISINPTAPQEVSVPTWNGFSLYTDETVRNAARYAYDNYLGKPYTGTVEATPVNFGGQMVYRQHHGLAHTL RTMAYAEIIVEEARKAKLRGESLKTFADGRTLADVTPEELRKIMIAQAFFVTGRDDEESSKNYEKYHEQS RDAFLKYVEENKSTLIPDVFKDEKDVKFYADVIEDKDHKWADSPAHVLVNQGHMVDLVRVKQPPESYLEY YFSQLQPWIGSTATEAVFATQRQFFHATYEAVAGFDSENKEPHLVVDGLGRYVIGQDGNPIREESDDEDE EESGELKFFSQKKKLEENQRYMRVDEYLKLDEVQKRFPGAGKKLDGGLPGLKEYQYLQRLNSINRARCEN DVDFCLGQLQTAHHQTKITPIKRAFQSSSDKVRRQPNMDEIAAARIIQQIMANPDCIHDDHVLLNGQKLE EKFFRNLLAKCDMAIVGSLLNDTDIRNIDTLMQHERNTEFHSTDAKAKPVKLGETWEKTIRSGGGVTQIK HDLIFLMQNDAWYHTRVNAIAQNRDKDSTFKEVLITALMTPLTNKSLIDTSRSPAPKTLFRGLDLSEEFK NKLINQAETIIANTTEHLFTDLSTEAFKQIKLNDFSQVSARTCASTSTNIEVPRTIFGSNTIFEILDPDG LLHPKQVGTHVSGSESEYSIYLPEDVALVPIKVSFDGKTGKGKDRHIFTLVAVKSPDFTPKHESGYAVEP LLKMQTPKLEEVQRLVEQAREEPDLERVFNLQSRVARQARFSTESGYKTFLNEKVAPVLEQSLNGLLDNN VTILGKALSAFPSDGQWSAFNSVEARQMKIQMDAIKQMVEKKAVLEGQILPALAQCQNALEKQNIAGALQ ALRNIPSEKEMQTMLSISGGLRGQIQRTKQDLTETLEPLQRAITSKLVSDQEKVNVRYEKLIASIPQRIA DLEKAALSDLAGVKKVVSHFNQLQEELKLLRNEKIRMHTGSEKIDFSDIAQLEAQLQKIHTKLYDAYLVE LTKEISALVKEKPKNLADVKRMVSNFYAMSADIEQLRQEKIKEHGESKDPIDMSDIDKLKEELQKINQFL VKAMGTNIRVSLNQMEVKTFDAQEKEAQQNLKQLDELINKLESSHAVQKQKEELEKLNQLLVEKRKAYPA MVQLQFRSEALIIHLRELCEAHQAQMAKTRNVRAQEITNGRWKVQWLTDWVGLTTDERVTLANKEKELAK FKEDLNNDEYDLQELISNLAEKNPSELEEAIGISKESAQKLHKLLTHLNHSTTFMNKIDQRLQSIDELLN EFGKQSPRTEMIKTVEEKQGTLLRL |
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Nucleotide Sequence: 4488 bp [Download] |
>gi|54292964|ref|NC_006369.1|:c327188-322701 Legionella pneumophila str. Lens, complete genome ATGCCTAAGTACGTTGAAGGGATAGAATTAACCCAAGAAGGGATGCATGCTATTTTTGAACGCATGGGAC ATCCAAATATTACCAGCGGTACTATCTACAACGGAGAGCCTACAATTGATAAAGGTGCTCTTGACAGGCA AGGCTTTATGCCAGTATTGACCGGGGTCAGCCCAAGGCAAGACTCGGGACATTGGATTATGTTAATTAAA GGTCAAGGCAATCAATATTTCCTCTTTGACCCGCTGGGAGAAAGCTCGGGAAAATATTACCAAAATATTT TAGCTAAAAAACTACCTGGCGCTACACTTTCTGTTATTCCTAATAATGCTGGATTAAATATGGGATTATG CGGCTATTGGGTTGCCTCAGTTGGTTTAAGAGCTCATGCGGCTTTAACACAACCTATTCCCCCTTCTTTA AGAAATGTGGGTCAAACCATTACCCAGGAAATGCGAGATGAACTAACACAAGATGGAAGCGAAAAAATTA CACAATGGTTACGGGCCGTTGGCAATGAATTTCCAGATGGTGATATACAACCTGATGCCACAGCCTTAAG ACGTGCTACTGAAAAGAATGTACGTATTGATGAGTTTCAGCCTGTTTTAACTGGAACATCACCTAAAGAA ATTTCGATAAATCCTACTGCTCCTCAAGAAGTATCCGTTCCCACGTGGAATGGTTTTTCCTTATATACTG ATGAAACCGTGAGAAATGCAGCAAGATACGCGTATGATAATTACTTGGGAAAACCTTATACCGGTACAGT AGAAGCGACACCTGTCAATTTTGGTGGGCAAATGGTATACAGGCAACACCATGGTCTTGCCCACACATTG CGCACCATGGCCTATGCGGAAATCATTGTTGAGGAAGCGCGAAAAGCAAAATTAAGGGGTGAATCATTAA AAACATTTGCTGATGGTCGTACTCTGGCGGATGTTACGCCTGAAGAATTGAGAAAAATCATGATCGCCCA GGCCTTCTTTGTCACTGGAAGAGACGATGAAGAATCCTCCAAGAATTATGAAAAATACCACGAACAAAGC CGAGATGCTTTTTTGAAATATGTCGAAGAGAATAAATCCACTTTAATTCCCGATGTATTCAAAGATGAAA AAGATGTCAAATTCTATGCTGATGTCATTGAAGATAAAGATCATAAATGGGCAGATTCACCGGCGCATGT CCTGGTCAATCAGGGCCATATGGTTGATTTGGTCAGAGTAAAACAACCCCCTGAATCTTACCTGGAATAC TATTTTTCACAACTTCAACCCTGGATAGGTTCAACAGCTACGGAAGCAGTTTTTGCGACACAGAGACAAT TCTTCCATGCCACCTATGAAGCAGTTGCGGGCTTTGATAGCGAAAACAAAGAACCTCATCTGGTGGTCGA TGGTTTAGGTCGCTATGTGATTGGACAAGATGGCAATCCAATACGCGAAGAATCTGATGACGAAGACGAG GAAGAATCAGGTGAATTAAAATTTTTCTCACAAAAAAAGAAACTCGAGGAAAACCAACGTTACATGCGCG TTGATGAATATTTAAAACTTGATGAGGTCCAAAAGCGATTCCCTGGCGCTGGTAAAAAACTCGATGGGGG GCTGCCTGGACTGAAAGAATATCAATATTTACAACGCTTGAACTCAATAAACAGAGCACGGTGTGAAAAC GACGTCGACTTTTGTTTGGGACAATTACAAACGGCACATCATCAAACCAAAATTACTCCAATAAAAAGAG CCTTCCAATCCAGCTCTGATAAAGTGAGAAGACAACCCAATATGGATGAAATTGCTGCTGCCCGTATTAT TCAGCAAATCATGGCCAATCCTGATTGCATCCATGACGATCATGTGCTGCTCAATGGTCAAAAACTGGAA GAAAAATTTTTCCGTAATTTGTTGGCGAAATGTGACATGGCTATTGTAGGGTCGCTATTAAACGATACAG ACATTAGAAATATCGACACCTTAATGCAACATGAGAGAAACACAGAATTTCACTCAACAGATGCCAAAGC AAAACCGGTGAAACTGGGAGAAACATGGGAAAAAACAATCAGATCGGGTGGTGGGGTTACTCAGATAAAA CATGATTTAATTTTCCTCATGCAAAATGATGCCTGGTACCATACTCGAGTCAATGCGATTGCGCAAAACC GGGATAAAGATTCAACATTCAAAGAAGTGTTGATTACCGCTTTAATGACACCATTGACTAACAAATCATT GATAGATACATCACGTTCCCCGGCCCCAAAAACGCTATTCCGTGGCTTGGATCTGTCAGAAGAGTTTAAA AATAAATTAATTAACCAGGCTGAAACCATCATTGCCAATACGACAGAACATCTCTTTACTGATCTGTCGA CAGAAGCCTTTAAACAAATTAAATTAAATGACTTTAGCCAGGTTTCTGCTAGAACTTGTGCCAGTACTTC CACTAACATTGAAGTTCCCAGGACAATCTTTGGCTCCAATACCATCTTTGAAATACTTGATCCCGATGGT TTATTACACCCCAAACAAGTTGGAACCCATGTATCAGGGTCAGAAAGTGAATATTCCATTTATTTGCCGG AAGATGTTGCCTTGGTTCCAATCAAAGTAAGCTTTGATGGAAAAACAGGTAAAGGCAAAGACCGACATAT TTTTACTTTAGTCGCGGTAAAAAGCCCTGATTTCACGCCAAAGCATGAAAGTGGTTATGCTGTTGAACCT CTTTTGAAAATGCAAACGCCAAAATTAGAAGAAGTTCAAAGATTAGTTGAGCAAGCAAGGGAAGAACCTG ACCTGGAAAGGGTATTCAATTTACAATCGAGAGTAGCAAGACAAGCCAGATTCTCCACTGAATCAGGATA TAAAACGTTTCTGAATGAAAAGGTGGCGCCTGTGTTGGAACAAAGCCTCAATGGCCTCTTGGACAATAAT GTAACCATTCTAGGCAAAGCATTATCAGCATTCCCTTCAGACGGCCAATGGTCTGCCTTTAATTCAGTTG AAGCAAGGCAAATGAAAATACAGATGGATGCCATTAAGCAAATGGTTGAAAAGAAAGCCGTCCTCGAAGG TCAAATTCTCCCTGCCTTGGCTCAATGCCAGAATGCTTTGGAGAAACAAAATATTGCAGGTGCATTACAA GCACTTAGAAACATCCCTTCTGAAAAAGAAATGCAAACCATGCTGTCAATTAGTGGTGGTTTGAGAGGAC AAATCCAGCGTACCAAGCAAGATTTGACTGAAACTCTGGAACCACTTCAACGCGCCATAACTTCTAAATT GGTAAGCGATCAAGAAAAAGTGAACGTGCGTTATGAAAAGCTGATAGCAAGCATACCTCAACGGATCGCC GATCTTGAAAAAGCTGCGCTTTCTGATCTTGCCGGTGTTAAAAAAGTTGTCTCTCATTTTAATCAGCTGC AAGAAGAATTAAAGTTGCTGCGTAATGAAAAAATTCGAATGCACACTGGCTCTGAAAAAATTGATTTTTC AGATATCGCACAATTAGAGGCGCAACTACAAAAAATCCATACTAAATTATATGACGCCTATTTGGTTGAA TTAACTAAAGAAATTTCAGCACTGGTTAAAGAAAAACCGAAAAACCTGGCCGACGTGAAAAGGATGGTTT CGAATTTCTATGCTATGTCAGCTGATATTGAACAATTGCGTCAGGAAAAGATAAAAGAACACGGTGAGTC AAAAGATCCGATTGATATGTCTGATATTGATAAATTAAAGGAAGAACTACAAAAAATTAATCAATTTTTA GTGAAGGCGATGGGAACTAATATCAGGGTTTCACTGAATCAAATGGAAGTAAAAACTTTTGATGCCCAGG AAAAGGAAGCACAACAAAATTTGAAGCAATTAGACGAACTGATTAATAAATTGGAAAGTTCTCATGCTGT ACAGAAACAAAAAGAAGAACTCGAAAAATTAAACCAATTGCTTGTCGAGAAGCGCAAAGCCTATCCCGCA ATGGTGCAGTTGCAATTCAGGAGTGAAGCATTAATTATCCATTTACGTGAATTATGTGAAGCTCATCAAG CTCAAATGGCTAAAACAAGAAATGTAAGGGCGCAAGAAATCACTAATGGACGATGGAAAGTACAATGGTT GACTGATTGGGTTGGTTTAACTACAGATGAGCGGGTAACTCTTGCCAACAAAGAAAAAGAATTGGCTAAA TTCAAGGAAGATTTAAATAATGACGAGTATGATTTGCAGGAACTCATCAGTAACCTGGCTGAGAAAAACC CGTCAGAATTGGAAGAAGCCATAGGGATATCTAAAGAGAGCGCTCAGAAATTGCATAAACTGTTAACTCA TCTAAACCACAGTACAACATTTATGAATAAAATCGACCAACGATTACAGTCTATTGATGAGCTATTAAAC GAGTTTGGCAAGCAATCGCCCCGAACTGAAATGATAAAAACTGTTGAGGAAAAACAAGGAACTCTCTTAA GATTGTAA |
Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] |
in silico analysis literature |