| Effector Protein ID: 54293188 |
 T4SS name [ID] | Dot/Icm [41] |
| Gene symbol | - |
| Locus tag | lpl0234 |
| Strain | Legionella pneumophila str. Lens |
| Replicon | chromosome [GenBank: NC_006369] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 259905..260471 [-] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | LegU1 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | LegU1 and Lpg2160 may function redundantly or in concert to modulate BAT3 activity during the course of infection. (Ensminger and Isberg, 2010) |
| UniProt ID | Q5WZZ5 |
| KEGG ID | lpf:lpl0234 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | F-box [PF00646], Evalue: 1.3e-05, Aligned region: 12..50 |
| Protein Sequence: 188 a.a. [Download] |
| >gi|54293188|ref|YP_125603.1| hypothetical protein lpl0234 [Legionella pneumophila str. Lens] MKAKYDSTEPGLQKLPPEIKVMILELLDAKSKLALSQSNYGWRDLIRHLPECTKEITNTLFRLDKKRHHQ EIVQMMSGRVTASSMAELFEELLCFSIPSSYVFLIFFISQKSVALIEVLTVILVFAALTSLTHDLVDYFI ESDTKAEKQHAHRRAFQFFAQPSSNAAQQNSEEDNLSADPKAWPCEPL |
| - |
| Nucleotide Sequence: 567 bp [Download] |
| >gi|54292964|ref|NC_006369.1|:c260471-259905 Legionella pneumophila str. Lens, complete genome ATGAAAGCAAAATACGACTCCACAGAGCCTGGACTCCAAAAGTTACCTCCTGAAATCAAGGTAATGATTC TTGAGCTTCTTGATGCCAAATCAAAACTTGCTCTTTCACAATCAAATTATGGTTGGCGTGATTTAATTCG ACATCTGCCAGAATGCACCAAAGAAATAACGAATACATTATTTCGTCTTGATAAAAAACGCCATCATCAA GAGATTGTACAAATGATGTCGGGAAGAGTTACAGCAAGTTCTATGGCTGAGCTATTTGAAGAATTACTAT GTTTTAGCATACCTTCGTCCTATGTGTTTTTAATCTTCTTCATATCGCAAAAATCTGTAGCGCTTATAGA AGTCTTAACTGTAATCCTTGTGTTTGCTGCACTAACCTCTCTCACCCATGATCTGGTTGATTATTTTATT GAAAGTGACACAAAAGCTGAGAAACAGCATGCACACCGCCGTGCTTTTCAATTCTTTGCCCAACCCAGTT CAAACGCTGCACAACAAAACTCGGAGGAAGATAATTTAAGTGCTGATCCCAAAGCCTGGCCATGTGAGCC ATTGTAG |
| Reference |
| (1) Rolando M; Buchrieser C (2012). Post-translational modifications of host proteins by Legionella pneumophila: a sophisticated survival strategy. Future Microbiol. 7(3):369-81. [PudMed:22393890] |
(2) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| in silico analysis literature |