Effector Protein ID: 54293097 |
T4SS name [ID] | Dot/Icm [41] |
Gene symbol | sdhB |
Locus tag | lpl0135 |
Strain | Legionella pneumophila str. Lens |
Replicon | chromosome [GenBank: NC_006369] [Browse all T4SS(s) in this replicon] |
Location [Strand] | 159856..165483 [-] |
Product | SdhB protein, substrate of the Dot/Icm system |
Effector type | Protein |
Descripton | SdhB |
T4CP requirement | T4CP Depedent |
Target/Effection | SdhB may play minor roles in Legionella replication |
UniProt ID | Q5X086 |
KEGG ID | lpf:lpl0135 |
PDB ID | NA |
Domain hit(s) vs Pfam | NA |
Protein Sequence: 1875 a.a. [Download] |
>gi|54293097|ref|YP_125512.1| SdhB protein, substrate of the Dot/Icm system [Legionella pneumophila str. Lens] MLLLSIEVINMPDHNSSDIPLSKQINEVRGLLLKALKAQLDDLIAEKLTPQPSGVPFVHFEKDPPQIATL KKVINCLYHAEEAFKSWESIDTSTLLGKAKAAPKLIRALTQIYKSLGLLDEATPEIRSVIADNYHLLEPL FTQAYTIVQESGWLSEFMEMDVTDKASKVIFQGMDLLGPDIGKSEDAHPLIDAFSKISKLVETVSTLQEK SMTGKEKERAVELVRSLLDDLDNNPFISKLSISDFEDSKAIKDLLEWFKNIQDDGFDFSKKSIQQYVSWA NHYLPTLITFADQLERQNYLKPGSLSTNLCSQIEHLGRQVNGILSEPNFGITERVVSIESLQGKREQEIH NAQVNSVRAIMATEKQQAATADFYRILEAYKGMNLSQVTEPDRILLRQLYPQIQTALAHASLDLENLLTS VLNTTGPEKTAPKPKSWWELAKDGLGYVASYVVNYNVDKILGTRESIDHFLSSQIASEQFKILIAEKARE KLRTGSDKLEETALQYKAEVRVNAIKSTLRKQPSPIEAPPSRFVAVKPSKLVNLRGTLTAIQEMQLSTTV KSTRTNVDTLIHRHLPEKYQACFSTLPYQVNEKEPELVKQIKTVENNLFQLEKALKDFEKIDLSYGIMIR LHYFIAIASAASKLKSSVKELSSEGQKALAPLLQQIMTLGSSFSDTNYTANDLSALQQLKTEGQAKPRGP LETSPEKTKTLPEETVKGNEKKPKEKTTELLDYADKISTARTLLLSKFKSTLSPAIADSLNPQEHGVPFV HLDQDPPQIAAIKKIINSMYHAECALKTWHGIDTSTTLGKIAAAHQGVAALSQVYKSFTLFTEDFSDIHN LIRENHDLIAPVIIEANKLVKEYGWASQFSELNVAQKLGSILGQGINTVQPKTDEITQTASLVKLFSEIP WLLNNMSSSLDQNAEKSVDELRINSKKIEAIGAVFELFFEENAYLLSIFKGFSAISGLLELNKKIQREGN NLQEVTIRQYQKWLKEGYPNLMMMLDEIETRHYLTPGLLSAPIALELDQINDKLNEIIETKPDFKLQKIP LSFYMGDKRMERLMAKKTEHGLALIQIEEQKKAVNTFFGILKHYAGQPLSNIKPNELVQLRFAFVKIQSA MANSNLELSNDLVAALNQLETSPPEEINKIKVTVSQLIKLQPAVENHLNEHKKSCELKIAVIDKAIEHVK DKSFELKSDVSKEINMPQLRRTFLEIEGKKPAIGPGELKPTSVSSLNTVRGNLAYIQELKLSSTVGMIRE QFSALTGDNFSTRVQKYLIKPQGKPLHVINDKDPLMVRQIKEVENGLYHLETALKQFEQMKKSDSLVSQT KALVEIANHAYELKMAVERFSPELKQHYGPVVRAALSFSNKVQSINYNKEDWADLQFILNRAHKELLKRK TPRDHRIEKAFFEAGIREVQIDRTESAGKKAAKLGVKYAHLASPQLEKARAYLSSRYRNAFGQQPKLIRS LTREQLANEEFMSAEISRLKEALEEKYGFNLSTIKVILDLLEQIQRAGAQAAEVAGMVNTLVTYDFPKIK ENAYRDLLTKLSQEEDYLNLKPGTLINPAMAAVNQLFLSAALELDMPFSKKLSILDDTTYINILVRQTES DLQTLKTKLSEDPSNHEIAFEIEIKNDKLVFLRQQMALLEDKNPNQTRNVLLDMQFEVSLRNHLVYTTLK APIAQEYEQIAREYYKKNKNRFLYADDCSKELLQGLKEFEKKHLPDHLIVFEAYDRLRLFSAKLPPKNQD VKEYIENINRELQNRDIPIEQRAIKVKSLPNDSVFIEKLSSADKGTHFLRKFMQFITIITASITEAIKTG GSLIYIYRQKQMEQSIKNIEKSISLKEELNTIKNTDGSSLRKGEGKEGEIEFTKM |
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Nucleotide Sequence: 5628 bp [Download] |
>gi|54292964|ref|NC_006369.1|:c165483-159856 Legionella pneumophila str. Lens, complete genome ATGCTACTATTAAGCATAGAGGTGATAAATATGCCAGATCATAACTCATCAGATATTCCGTTATCGAAGC AAATAAATGAAGTCAGGGGGTTGCTTCTTAAGGCCCTTAAAGCGCAATTGGATGATCTGATAGCTGAAAA ACTCACTCCACAACCAAGTGGCGTTCCTTTTGTTCATTTTGAGAAGGATCCACCACAAATTGCAACTCTA AAAAAAGTCATTAATTGTCTTTATCATGCTGAGGAAGCATTTAAAAGCTGGGAAAGCATTGATACCAGTA CGCTATTGGGTAAAGCCAAAGCAGCACCCAAATTAATCCGTGCACTAACCCAGATATACAAATCCCTGGG TTTACTTGATGAAGCTACCCCTGAAATAAGGAGTGTCATAGCCGACAATTATCATTTACTTGAACCGCTG TTTACTCAAGCTTATACCATAGTGCAAGAGTCTGGCTGGTTATCAGAATTCATGGAAATGGATGTGACTG ATAAAGCCTCCAAAGTGATCTTTCAAGGAATGGATTTACTAGGTCCTGATATAGGCAAATCAGAGGATGC GCATCCACTTATTGACGCTTTTTCAAAAATATCAAAACTGGTAGAAACCGTATCCACACTACAAGAAAAG AGCATGACAGGAAAAGAGAAAGAACGAGCCGTAGAATTGGTTCGTTCTTTACTTGATGACTTGGACAATA ATCCTTTTATCAGTAAATTAAGTATCAGTGATTTTGAAGACTCAAAAGCCATAAAGGATTTATTAGAATG GTTTAAGAACATACAAGACGATGGTTTTGATTTTAGCAAGAAATCTATTCAGCAATATGTTTCCTGGGCT AATCACTATTTACCCACATTAATCACCTTCGCTGATCAACTGGAACGACAAAACTATTTAAAACCAGGCA GTTTAAGTACCAATTTATGTTCTCAAATAGAGCATTTAGGCAGGCAAGTGAATGGCATACTATCTGAACC TAATTTTGGTATTACTGAGCGCGTTGTATCCATAGAATCATTGCAGGGGAAAAGAGAGCAAGAAATTCAT AATGCTCAGGTCAACAGTGTGCGAGCTATCATGGCTACCGAAAAACAGCAAGCGGCTACTGCTGATTTTT ATCGGATCCTGGAAGCCTATAAAGGCATGAATCTTTCACAAGTCACAGAGCCGGATCGGATATTACTAAG ACAATTATATCCCCAAATACAAACAGCACTGGCTCATGCCAGCTTGGACCTTGAAAATCTGTTAACCTCT GTTTTAAATACTACCGGCCCTGAAAAAACCGCACCCAAACCCAAATCATGGTGGGAATTAGCCAAAGATG GTTTAGGTTATGTAGCCAGTTATGTAGTAAATTACAACGTTGATAAAATCCTGGGAACCAGAGAATCTAT TGATCATTTTCTGTCAAGCCAAATTGCTTCCGAACAATTTAAGATCCTGATTGCTGAAAAAGCTCGTGAA AAATTAAGGACCGGGTCAGATAAGCTAGAAGAAACCGCGCTGCAATATAAAGCCGAAGTTCGTGTCAATG CTATAAAATCAACTCTGAGAAAGCAACCTTCTCCGATAGAAGCTCCTCCCTCCCGGTTTGTTGCAGTAAA ACCTTCGAAATTAGTCAATCTTCGTGGAACACTAACTGCTATTCAGGAAATGCAATTATCGACTACAGTA AAGAGCACAAGAACAAATGTCGATACTCTGATTCATCGCCATTTGCCAGAAAAATATCAAGCCTGTTTTT CAACTCTTCCATATCAAGTCAATGAAAAGGAGCCTGAGTTGGTGAAACAAATTAAAACCGTTGAAAATAA TTTGTTTCAATTAGAAAAAGCGCTTAAAGATTTTGAAAAAATCGATTTGAGCTATGGGATTATGATCCGA TTGCATTATTTTATCGCAATCGCTTCTGCAGCCTCCAAACTAAAATCAAGTGTCAAAGAACTTTCATCAG AGGGTCAAAAAGCGCTGGCTCCACTGTTGCAACAAATTATGACTTTAGGGTCATCTTTCTCAGACACCAA TTATACAGCTAATGACTTATCTGCCTTGCAACAATTAAAAACAGAAGGCCAAGCCAAACCCAGAGGTCCA CTCGAAACATCTCCGGAAAAAACAAAAACATTACCTGAAGAAACTGTAAAGGGAAATGAAAAAAAACCAA AAGAAAAAACGACTGAATTATTGGATTATGCTGATAAAATCAGTACTGCTCGGACATTGTTATTAAGCAA GTTTAAATCCACCTTATCTCCTGCCATAGCTGACAGTCTAAACCCACAGGAACATGGCGTTCCATTTGTT CATCTTGATCAAGACCCGCCACAAATCGCGGCAATAAAAAAAATCATCAACAGTATGTATCATGCAGAGT GTGCTCTTAAGACCTGGCATGGCATAGACACCAGCACTACATTGGGTAAGATTGCTGCAGCACATCAAGG CGTAGCGGCATTATCGCAAGTGTACAAATCATTTACGTTGTTTACTGAGGATTTCTCAGACATTCACAAT TTAATTCGTGAGAATCACGATTTAATAGCACCTGTGATCATCGAAGCAAACAAGCTGGTTAAAGAGTATG GATGGGCAAGTCAATTCAGTGAACTTAATGTAGCGCAAAAGCTGGGAAGCATTTTAGGTCAGGGAATTAA TACAGTTCAACCTAAAACGGATGAAATAACACAAACCGCTTCACTAGTTAAATTATTTTCAGAAATTCCA TGGCTACTGAACAATATGTCAAGTTCATTGGATCAAAACGCTGAGAAATCAGTTGATGAGTTAAGAATCA ACAGCAAAAAAATTGAAGCCATAGGTGCAGTATTTGAATTGTTCTTTGAAGAAAATGCTTACTTGTTGAG TATTTTTAAAGGATTCAGCGCCATCTCTGGTCTTCTTGAATTAAATAAAAAAATTCAACGCGAAGGAAAC AACCTGCAAGAAGTCACTATTCGACAATACCAGAAATGGTTAAAAGAAGGTTATCCCAATTTGATGATGA TGCTTGATGAAATTGAGACACGTCACTACTTAACCCCAGGCCTTTTATCAGCACCTATAGCCTTGGAATT AGACCAAATTAACGACAAACTCAATGAAATTATTGAAACCAAGCCTGATTTTAAATTGCAAAAAATTCCT CTTTCATTCTATATGGGCGACAAGCGCATGGAGCGCTTAATGGCTAAAAAAACGGAACACGGCCTCGCAT TGATCCAAATAGAAGAGCAAAAAAAAGCGGTTAACACTTTTTTCGGGATACTTAAACACTATGCAGGTCA ACCACTCTCCAACATAAAGCCAAATGAGCTCGTTCAATTGCGCTTTGCTTTTGTAAAAATTCAATCCGCA ATGGCAAATAGTAATTTGGAATTAAGCAATGATTTGGTTGCTGCTTTAAATCAACTTGAAACGTCCCCAC CTGAAGAGATCAATAAAATCAAGGTGACAGTCTCTCAATTGATAAAATTGCAGCCTGCTGTTGAAAACCA TTTAAACGAACACAAAAAATCCTGTGAATTAAAAATAGCAGTCATTGACAAAGCCATCGAGCACGTCAAA GATAAATCGTTCGAGCTGAAATCTGATGTATCAAAAGAAATCAATATGCCCCAACTGCGCAGAACATTTT TAGAAATCGAAGGCAAGAAACCTGCTATAGGCCCTGGAGAATTAAAACCAACATCGGTCTCATCTCTTAA CACCGTTCGTGGTAATTTAGCTTACATTCAAGAATTAAAATTGTCATCCACTGTGGGTATGATACGAGAG CAATTTTCGGCTCTTACCGGAGATAATTTCTCCACTCGAGTGCAAAAATATTTAATCAAACCCCAAGGTA AACCGTTGCATGTGATAAATGACAAAGATCCACTCATGGTAAGGCAAATTAAAGAAGTTGAAAACGGATT ATATCACCTGGAAACCGCTTTAAAACAATTCGAGCAAATGAAAAAGAGCGACAGCCTTGTATCGCAAACA AAAGCGTTGGTAGAAATTGCAAACCATGCTTATGAATTAAAAATGGCAGTGGAACGATTTTCACCCGAGT TAAAACAGCATTATGGCCCAGTAGTTCGTGCCGCATTGAGTTTCAGTAATAAAGTTCAATCCATCAATTA CAACAAAGAGGATTGGGCTGATCTTCAGTTTATTCTTAATAGAGCCCATAAAGAATTGTTAAAAAGAAAA ACACCAAGAGACCATCGTATTGAAAAGGCATTTTTTGAAGCTGGAATTCGTGAAGTACAAATCGATCGGA CTGAATCAGCAGGAAAAAAAGCGGCAAAACTGGGTGTAAAATACGCGCATCTGGCCTCCCCTCAGTTAGA GAAAGCAAGAGCCTATTTAAGTTCCAGATACAGAAATGCGTTTGGCCAACAACCCAAGCTTATTCGTTCG TTGACTCGAGAACAATTGGCGAATGAAGAATTTATGAGCGCTGAAATTAGCAGATTGAAAGAAGCATTAG AGGAGAAGTATGGTTTTAATCTTAGCACGATCAAGGTTATTCTTGATTTGTTAGAACAAATTCAACGGGC AGGGGCGCAGGCCGCTGAGGTAGCTGGTATGGTCAATACCTTGGTTACTTATGACTTCCCCAAAATAAAA GAAAATGCGTACAGGGATTTACTTACTAAACTATCTCAAGAAGAAGACTACCTGAATTTAAAACCAGGCA CATTAATTAATCCAGCCATGGCCGCAGTCAATCAATTATTCTTATCCGCAGCCCTGGAATTAGATATGCC TTTTAGTAAAAAGTTATCTATTCTGGACGATACCACTTATATCAATATTCTTGTCAGACAAACCGAAAGC GATCTGCAAACATTAAAGACAAAGTTATCCGAAGATCCCTCGAATCATGAAATAGCATTTGAAATTGAGA TTAAGAACGATAAATTAGTGTTCCTCAGGCAACAGATGGCCTTGCTTGAAGATAAAAACCCCAATCAAAC CAGAAATGTCTTATTGGACATGCAGTTCGAGGTCTCATTACGTAACCATCTTGTTTATACAACACTTAAA GCACCCATTGCCCAGGAATATGAACAAATTGCCAGAGAATATTACAAAAAAAACAAAAATCGCTTTCTAT ATGCCGATGACTGTTCAAAAGAGTTGCTGCAAGGATTGAAAGAATTTGAAAAAAAACATTTGCCTGATCA TTTGATAGTTTTTGAAGCCTATGACAGGCTTCGCCTATTCAGTGCAAAACTTCCCCCTAAAAATCAGGAC GTCAAAGAGTATATTGAGAACATCAATAGAGAATTACAAAATAGAGATATCCCTATAGAACAACGTGCTA TAAAAGTTAAATCATTACCTAATGACTCTGTCTTTATTGAAAAATTAAGTTCAGCTGATAAAGGCACTCA TTTCCTAAGAAAATTCATGCAGTTCATTACAATCATTACAGCAAGTATCACCGAAGCAATAAAAACCGGG GGCAGTTTGATTTATATTTATCGCCAAAAACAAATGGAACAATCCATAAAGAATATTGAAAAATCGATAA GCCTTAAAGAAGAACTCAATACCATAAAAAATACGGATGGCTCTTCACTGCGCAAGGGAGAGGGAAAAGA AGGTGAAATCGAGTTTACCAAAATGTAA |
Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] |
in silico analysis literature |