SecReT4
Effector Protein ID: 54293097
T4SS name [ID]Dot/Icm [41]
Gene symbolsdhB
Locus taglpl0135
StrainLegionella pneumophila str. Lens
Repliconchromosome [GenBank: NC_006369] [Browse all T4SS(s) in this replicon]
Location [Strand]159856..165483 [-]
ProductSdhB protein, substrate of the Dot/Icm system
Effector typeProtein
DescriptonSdhB
T4CP requirementT4CP Depedent
Target/EffectionSdhB may play minor roles in Legionella replication
UniProt IDQ5X086
KEGG IDlpf:lpl0135
PDB IDNA
Domain hit(s) vs Pfam NA
Protein Sequence: 1875 a.a.     [Download]
>gi|54293097|ref|YP_125512.1| SdhB protein, substrate of the Dot/Icm system [Legionella pneumophila str. Lens]
MLLLSIEVINMPDHNSSDIPLSKQINEVRGLLLKALKAQLDDLIAEKLTPQPSGVPFVHFEKDPPQIATL
KKVINCLYHAEEAFKSWESIDTSTLLGKAKAAPKLIRALTQIYKSLGLLDEATPEIRSVIADNYHLLEPL
FTQAYTIVQESGWLSEFMEMDVTDKASKVIFQGMDLLGPDIGKSEDAHPLIDAFSKISKLVETVSTLQEK
SMTGKEKERAVELVRSLLDDLDNNPFISKLSISDFEDSKAIKDLLEWFKNIQDDGFDFSKKSIQQYVSWA
NHYLPTLITFADQLERQNYLKPGSLSTNLCSQIEHLGRQVNGILSEPNFGITERVVSIESLQGKREQEIH
NAQVNSVRAIMATEKQQAATADFYRILEAYKGMNLSQVTEPDRILLRQLYPQIQTALAHASLDLENLLTS
VLNTTGPEKTAPKPKSWWELAKDGLGYVASYVVNYNVDKILGTRESIDHFLSSQIASEQFKILIAEKARE
KLRTGSDKLEETALQYKAEVRVNAIKSTLRKQPSPIEAPPSRFVAVKPSKLVNLRGTLTAIQEMQLSTTV
KSTRTNVDTLIHRHLPEKYQACFSTLPYQVNEKEPELVKQIKTVENNLFQLEKALKDFEKIDLSYGIMIR
LHYFIAIASAASKLKSSVKELSSEGQKALAPLLQQIMTLGSSFSDTNYTANDLSALQQLKTEGQAKPRGP
LETSPEKTKTLPEETVKGNEKKPKEKTTELLDYADKISTARTLLLSKFKSTLSPAIADSLNPQEHGVPFV
HLDQDPPQIAAIKKIINSMYHAECALKTWHGIDTSTTLGKIAAAHQGVAALSQVYKSFTLFTEDFSDIHN
LIRENHDLIAPVIIEANKLVKEYGWASQFSELNVAQKLGSILGQGINTVQPKTDEITQTASLVKLFSEIP
WLLNNMSSSLDQNAEKSVDELRINSKKIEAIGAVFELFFEENAYLLSIFKGFSAISGLLELNKKIQREGN
NLQEVTIRQYQKWLKEGYPNLMMMLDEIETRHYLTPGLLSAPIALELDQINDKLNEIIETKPDFKLQKIP
LSFYMGDKRMERLMAKKTEHGLALIQIEEQKKAVNTFFGILKHYAGQPLSNIKPNELVQLRFAFVKIQSA
MANSNLELSNDLVAALNQLETSPPEEINKIKVTVSQLIKLQPAVENHLNEHKKSCELKIAVIDKAIEHVK
DKSFELKSDVSKEINMPQLRRTFLEIEGKKPAIGPGELKPTSVSSLNTVRGNLAYIQELKLSSTVGMIRE
QFSALTGDNFSTRVQKYLIKPQGKPLHVINDKDPLMVRQIKEVENGLYHLETALKQFEQMKKSDSLVSQT
KALVEIANHAYELKMAVERFSPELKQHYGPVVRAALSFSNKVQSINYNKEDWADLQFILNRAHKELLKRK
TPRDHRIEKAFFEAGIREVQIDRTESAGKKAAKLGVKYAHLASPQLEKARAYLSSRYRNAFGQQPKLIRS
LTREQLANEEFMSAEISRLKEALEEKYGFNLSTIKVILDLLEQIQRAGAQAAEVAGMVNTLVTYDFPKIK
ENAYRDLLTKLSQEEDYLNLKPGTLINPAMAAVNQLFLSAALELDMPFSKKLSILDDTTYINILVRQTES
DLQTLKTKLSEDPSNHEIAFEIEIKNDKLVFLRQQMALLEDKNPNQTRNVLLDMQFEVSLRNHLVYTTLK
APIAQEYEQIAREYYKKNKNRFLYADDCSKELLQGLKEFEKKHLPDHLIVFEAYDRLRLFSAKLPPKNQD
VKEYIENINRELQNRDIPIEQRAIKVKSLPNDSVFIEKLSSADKGTHFLRKFMQFITIITASITEAIKTG
GSLIYIYRQKQMEQSIKNIEKSISLKEELNTIKNTDGSSLRKGEGKEGEIEFTKM
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Nucleotide Sequence: 5628 bp     [Download]
>gi|54292964|ref|NC_006369.1|:c165483-159856 Legionella pneumophila str. Lens, complete genome
ATGCTACTATTAAGCATAGAGGTGATAAATATGCCAGATCATAACTCATCAGATATTCCGTTATCGAAGC
AAATAAATGAAGTCAGGGGGTTGCTTCTTAAGGCCCTTAAAGCGCAATTGGATGATCTGATAGCTGAAAA
ACTCACTCCACAACCAAGTGGCGTTCCTTTTGTTCATTTTGAGAAGGATCCACCACAAATTGCAACTCTA
AAAAAAGTCATTAATTGTCTTTATCATGCTGAGGAAGCATTTAAAAGCTGGGAAAGCATTGATACCAGTA
CGCTATTGGGTAAAGCCAAAGCAGCACCCAAATTAATCCGTGCACTAACCCAGATATACAAATCCCTGGG
TTTACTTGATGAAGCTACCCCTGAAATAAGGAGTGTCATAGCCGACAATTATCATTTACTTGAACCGCTG
TTTACTCAAGCTTATACCATAGTGCAAGAGTCTGGCTGGTTATCAGAATTCATGGAAATGGATGTGACTG
ATAAAGCCTCCAAAGTGATCTTTCAAGGAATGGATTTACTAGGTCCTGATATAGGCAAATCAGAGGATGC
GCATCCACTTATTGACGCTTTTTCAAAAATATCAAAACTGGTAGAAACCGTATCCACACTACAAGAAAAG
AGCATGACAGGAAAAGAGAAAGAACGAGCCGTAGAATTGGTTCGTTCTTTACTTGATGACTTGGACAATA
ATCCTTTTATCAGTAAATTAAGTATCAGTGATTTTGAAGACTCAAAAGCCATAAAGGATTTATTAGAATG
GTTTAAGAACATACAAGACGATGGTTTTGATTTTAGCAAGAAATCTATTCAGCAATATGTTTCCTGGGCT
AATCACTATTTACCCACATTAATCACCTTCGCTGATCAACTGGAACGACAAAACTATTTAAAACCAGGCA
GTTTAAGTACCAATTTATGTTCTCAAATAGAGCATTTAGGCAGGCAAGTGAATGGCATACTATCTGAACC
TAATTTTGGTATTACTGAGCGCGTTGTATCCATAGAATCATTGCAGGGGAAAAGAGAGCAAGAAATTCAT
AATGCTCAGGTCAACAGTGTGCGAGCTATCATGGCTACCGAAAAACAGCAAGCGGCTACTGCTGATTTTT
ATCGGATCCTGGAAGCCTATAAAGGCATGAATCTTTCACAAGTCACAGAGCCGGATCGGATATTACTAAG
ACAATTATATCCCCAAATACAAACAGCACTGGCTCATGCCAGCTTGGACCTTGAAAATCTGTTAACCTCT
GTTTTAAATACTACCGGCCCTGAAAAAACCGCACCCAAACCCAAATCATGGTGGGAATTAGCCAAAGATG
GTTTAGGTTATGTAGCCAGTTATGTAGTAAATTACAACGTTGATAAAATCCTGGGAACCAGAGAATCTAT
TGATCATTTTCTGTCAAGCCAAATTGCTTCCGAACAATTTAAGATCCTGATTGCTGAAAAAGCTCGTGAA
AAATTAAGGACCGGGTCAGATAAGCTAGAAGAAACCGCGCTGCAATATAAAGCCGAAGTTCGTGTCAATG
CTATAAAATCAACTCTGAGAAAGCAACCTTCTCCGATAGAAGCTCCTCCCTCCCGGTTTGTTGCAGTAAA
ACCTTCGAAATTAGTCAATCTTCGTGGAACACTAACTGCTATTCAGGAAATGCAATTATCGACTACAGTA
AAGAGCACAAGAACAAATGTCGATACTCTGATTCATCGCCATTTGCCAGAAAAATATCAAGCCTGTTTTT
CAACTCTTCCATATCAAGTCAATGAAAAGGAGCCTGAGTTGGTGAAACAAATTAAAACCGTTGAAAATAA
TTTGTTTCAATTAGAAAAAGCGCTTAAAGATTTTGAAAAAATCGATTTGAGCTATGGGATTATGATCCGA
TTGCATTATTTTATCGCAATCGCTTCTGCAGCCTCCAAACTAAAATCAAGTGTCAAAGAACTTTCATCAG
AGGGTCAAAAAGCGCTGGCTCCACTGTTGCAACAAATTATGACTTTAGGGTCATCTTTCTCAGACACCAA
TTATACAGCTAATGACTTATCTGCCTTGCAACAATTAAAAACAGAAGGCCAAGCCAAACCCAGAGGTCCA
CTCGAAACATCTCCGGAAAAAACAAAAACATTACCTGAAGAAACTGTAAAGGGAAATGAAAAAAAACCAA
AAGAAAAAACGACTGAATTATTGGATTATGCTGATAAAATCAGTACTGCTCGGACATTGTTATTAAGCAA
GTTTAAATCCACCTTATCTCCTGCCATAGCTGACAGTCTAAACCCACAGGAACATGGCGTTCCATTTGTT
CATCTTGATCAAGACCCGCCACAAATCGCGGCAATAAAAAAAATCATCAACAGTATGTATCATGCAGAGT
GTGCTCTTAAGACCTGGCATGGCATAGACACCAGCACTACATTGGGTAAGATTGCTGCAGCACATCAAGG
CGTAGCGGCATTATCGCAAGTGTACAAATCATTTACGTTGTTTACTGAGGATTTCTCAGACATTCACAAT
TTAATTCGTGAGAATCACGATTTAATAGCACCTGTGATCATCGAAGCAAACAAGCTGGTTAAAGAGTATG
GATGGGCAAGTCAATTCAGTGAACTTAATGTAGCGCAAAAGCTGGGAAGCATTTTAGGTCAGGGAATTAA
TACAGTTCAACCTAAAACGGATGAAATAACACAAACCGCTTCACTAGTTAAATTATTTTCAGAAATTCCA
TGGCTACTGAACAATATGTCAAGTTCATTGGATCAAAACGCTGAGAAATCAGTTGATGAGTTAAGAATCA
ACAGCAAAAAAATTGAAGCCATAGGTGCAGTATTTGAATTGTTCTTTGAAGAAAATGCTTACTTGTTGAG
TATTTTTAAAGGATTCAGCGCCATCTCTGGTCTTCTTGAATTAAATAAAAAAATTCAACGCGAAGGAAAC
AACCTGCAAGAAGTCACTATTCGACAATACCAGAAATGGTTAAAAGAAGGTTATCCCAATTTGATGATGA
TGCTTGATGAAATTGAGACACGTCACTACTTAACCCCAGGCCTTTTATCAGCACCTATAGCCTTGGAATT
AGACCAAATTAACGACAAACTCAATGAAATTATTGAAACCAAGCCTGATTTTAAATTGCAAAAAATTCCT
CTTTCATTCTATATGGGCGACAAGCGCATGGAGCGCTTAATGGCTAAAAAAACGGAACACGGCCTCGCAT
TGATCCAAATAGAAGAGCAAAAAAAAGCGGTTAACACTTTTTTCGGGATACTTAAACACTATGCAGGTCA
ACCACTCTCCAACATAAAGCCAAATGAGCTCGTTCAATTGCGCTTTGCTTTTGTAAAAATTCAATCCGCA
ATGGCAAATAGTAATTTGGAATTAAGCAATGATTTGGTTGCTGCTTTAAATCAACTTGAAACGTCCCCAC
CTGAAGAGATCAATAAAATCAAGGTGACAGTCTCTCAATTGATAAAATTGCAGCCTGCTGTTGAAAACCA
TTTAAACGAACACAAAAAATCCTGTGAATTAAAAATAGCAGTCATTGACAAAGCCATCGAGCACGTCAAA
GATAAATCGTTCGAGCTGAAATCTGATGTATCAAAAGAAATCAATATGCCCCAACTGCGCAGAACATTTT
TAGAAATCGAAGGCAAGAAACCTGCTATAGGCCCTGGAGAATTAAAACCAACATCGGTCTCATCTCTTAA
CACCGTTCGTGGTAATTTAGCTTACATTCAAGAATTAAAATTGTCATCCACTGTGGGTATGATACGAGAG
CAATTTTCGGCTCTTACCGGAGATAATTTCTCCACTCGAGTGCAAAAATATTTAATCAAACCCCAAGGTA
AACCGTTGCATGTGATAAATGACAAAGATCCACTCATGGTAAGGCAAATTAAAGAAGTTGAAAACGGATT
ATATCACCTGGAAACCGCTTTAAAACAATTCGAGCAAATGAAAAAGAGCGACAGCCTTGTATCGCAAACA
AAAGCGTTGGTAGAAATTGCAAACCATGCTTATGAATTAAAAATGGCAGTGGAACGATTTTCACCCGAGT
TAAAACAGCATTATGGCCCAGTAGTTCGTGCCGCATTGAGTTTCAGTAATAAAGTTCAATCCATCAATTA
CAACAAAGAGGATTGGGCTGATCTTCAGTTTATTCTTAATAGAGCCCATAAAGAATTGTTAAAAAGAAAA
ACACCAAGAGACCATCGTATTGAAAAGGCATTTTTTGAAGCTGGAATTCGTGAAGTACAAATCGATCGGA
CTGAATCAGCAGGAAAAAAAGCGGCAAAACTGGGTGTAAAATACGCGCATCTGGCCTCCCCTCAGTTAGA
GAAAGCAAGAGCCTATTTAAGTTCCAGATACAGAAATGCGTTTGGCCAACAACCCAAGCTTATTCGTTCG
TTGACTCGAGAACAATTGGCGAATGAAGAATTTATGAGCGCTGAAATTAGCAGATTGAAAGAAGCATTAG
AGGAGAAGTATGGTTTTAATCTTAGCACGATCAAGGTTATTCTTGATTTGTTAGAACAAATTCAACGGGC
AGGGGCGCAGGCCGCTGAGGTAGCTGGTATGGTCAATACCTTGGTTACTTATGACTTCCCCAAAATAAAA
GAAAATGCGTACAGGGATTTACTTACTAAACTATCTCAAGAAGAAGACTACCTGAATTTAAAACCAGGCA
CATTAATTAATCCAGCCATGGCCGCAGTCAATCAATTATTCTTATCCGCAGCCCTGGAATTAGATATGCC
TTTTAGTAAAAAGTTATCTATTCTGGACGATACCACTTATATCAATATTCTTGTCAGACAAACCGAAAGC
GATCTGCAAACATTAAAGACAAAGTTATCCGAAGATCCCTCGAATCATGAAATAGCATTTGAAATTGAGA
TTAAGAACGATAAATTAGTGTTCCTCAGGCAACAGATGGCCTTGCTTGAAGATAAAAACCCCAATCAAAC
CAGAAATGTCTTATTGGACATGCAGTTCGAGGTCTCATTACGTAACCATCTTGTTTATACAACACTTAAA
GCACCCATTGCCCAGGAATATGAACAAATTGCCAGAGAATATTACAAAAAAAACAAAAATCGCTTTCTAT
ATGCCGATGACTGTTCAAAAGAGTTGCTGCAAGGATTGAAAGAATTTGAAAAAAAACATTTGCCTGATCA
TTTGATAGTTTTTGAAGCCTATGACAGGCTTCGCCTATTCAGTGCAAAACTTCCCCCTAAAAATCAGGAC
GTCAAAGAGTATATTGAGAACATCAATAGAGAATTACAAAATAGAGATATCCCTATAGAACAACGTGCTA
TAAAAGTTAAATCATTACCTAATGACTCTGTCTTTATTGAAAAATTAAGTTCAGCTGATAAAGGCACTCA
TTTCCTAAGAAAATTCATGCAGTTCATTACAATCATTACAGCAAGTATCACCGAAGCAATAAAAACCGGG
GGCAGTTTGATTTATATTTATCGCCAAAAACAAATGGAACAATCCATAAAGAATATTGAAAAATCGATAA
GCCTTAAAGAAGAACTCAATACCATAAAAAATACGGATGGCTCTTCACTGCGCAAGGGAGAGGGAAAAGA
AGGTGAAATCGAGTTTACCAAAATGTAA

Reference
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] in_silico
 
in_silico in silico analysis literature