| Effector Protein ID: 52843099 |
 T4SS name [ID] | Dot/Icm [5] |
| Gene symbol | - |
| Locus tag | lpg2905 |
| Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
| Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 3286884..3288533 [+] |
| Product | ubiquinone biosynthesis AarF |
| Effector type | Protein |
| Descripton | LncP |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Manipulation of mitochondrial metabolite membrane transport. |
| UniProt ID | Q5ZRH7 |
| KEGG ID | lpn:lpg2905 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | ABC1 [PF03109], Evalue: 1.9e-34, Aligned region: 112-231 |
| Protein Sequence: 549 a.a. [Download] |
| >gi|52843099|ref|YP_096898.1| ubiquinone biosynthesis AarF [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MKSIKQLIRLIHINYILAKNGLDNVVVSIKLFAPLRFIVYLNPWNWLRKEKLTRGEALRKSLEELGPIFI KFGQALSTRPDILPEDIAKELSKLQDKVPPFPSHIAMNIIEQAYKQSAYDVFAQFDPIALASASMAQVHA ATLKTGENVVVKILRPNMRRLIEQDLSIMYTIAALADRYWPEGKRFKPKEIVKEFEHTLLDELDLMREAA NAAQLRRNFNQSPMLYIPEIYWDYCHHNILVIERIHGIPVTDIASLRDHGIDIKKLAERGVEIFFTQVFR DCFFHADMHPGNIFVSYQNPKDPQYICVDFGIIGTLTDNDKRYLAENLVAFFNRDYKRVAELHVESGWVS RDTPVAEFESSIRTVCEPIFEKPLKDISFGQVVFRLFQVARRFHMEVQPQLILLQKTLLAIEGLGRQLYP ELDLWATAKPFLEKWVREQMGPKAFIKRLKQNLPFFTEQLPHMPKLIFDILEMKKDQLLTVHELTRLQSE NNNQTIQWKSMGLGVFFSFLSLGVISYFDLLDYNHLTTITIAGSVLAGIFVLINRKIRN |
| - |
| Nucleotide Sequence: 1650 bp [Download] |
| >gi|52840256|ref|NC_002942.5|:3286884-3288533 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome ATGAAATCAATTAAGCAACTTATTCGTCTTATACATATCAATTATATTTTAGCCAAAAATGGTCTAGATA ATGTTGTTGTGTCTATCAAACTGTTTGCTCCTTTACGTTTTATAGTGTATTTAAACCCATGGAACTGGCT TCGCAAGGAGAAATTAACGCGCGGTGAAGCGCTGCGCAAATCGCTGGAGGAACTCGGCCCCATCTTCATT AAATTCGGACAAGCCCTTTCCACACGCCCCGATATACTTCCTGAAGACATCGCAAAAGAATTAAGTAAAC TGCAAGACAAAGTTCCTCCATTCCCCAGCCATATCGCCATGAACATCATTGAACAGGCCTATAAACAGTC TGCCTATGATGTTTTTGCCCAATTTGATCCGATCGCCCTGGCTTCCGCTTCCATGGCACAAGTACATGCG GCAACCCTGAAGACAGGGGAAAATGTCGTTGTAAAAATACTAAGGCCCAATATGCGCCGGCTTATAGAAC AAGATTTAAGTATCATGTACACCATCGCCGCATTGGCTGACCGCTATTGGCCTGAGGGAAAGCGCTTCAA ACCCAAAGAGATAGTCAAGGAATTTGAACATACCTTACTGGATGAACTGGATTTAATGAGAGAAGCGGCA AATGCCGCTCAATTGCGAAGAAATTTCAATCAATCTCCGATGTTATATATACCTGAAATCTATTGGGATT ATTGCCATCATAATATCCTGGTCATTGAACGCATTCATGGCATACCCGTGACCGATATAGCCAGTCTTAG AGATCACGGCATTGACATTAAAAAACTGGCCGAGCGTGGGGTAGAAATTTTCTTTACTCAAGTCTTCCGG GATTGTTTTTTTCATGCAGACATGCACCCGGGAAATATCTTTGTCTCCTACCAAAACCCCAAAGACCCTC AGTATATTTGTGTTGATTTTGGCATCATTGGGACTCTGACAGATAATGACAAGCGTTATCTGGCTGAAAA CCTGGTCGCTTTTTTTAACCGTGACTACAAGCGCGTAGCGGAATTACATGTGGAGTCAGGATGGGTATCG CGTGACACCCCTGTTGCAGAATTTGAAAGCAGCATAAGAACCGTTTGCGAACCTATTTTTGAAAAGCCAT TAAAAGATATTTCCTTTGGACAAGTGGTTTTCCGTTTATTCCAGGTTGCCAGAAGGTTTCATATGGAAGT GCAGCCCCAACTGATTTTGCTGCAAAAAACCCTGTTGGCGATAGAAGGTTTGGGCAGACAACTCTATCCT GAATTGGATTTATGGGCTACAGCAAAACCATTCCTTGAAAAATGGGTGCGGGAACAAATGGGGCCTAAAG CATTCATTAAACGCTTAAAGCAAAATCTGCCCTTTTTTACCGAGCAACTCCCCCATATGCCCAAACTGAT TTTTGATATATTGGAGATGAAAAAGGATCAGTTGTTAACAGTCCATGAACTCACACGCTTGCAATCTGAA AATAACAATCAGACCATCCAATGGAAGAGTATGGGACTGGGTGTATTTTTCTCATTTTTATCATTAGGCG TCATTAGCTATTTTGATTTGCTGGATTATAATCATCTCACAACCATCACGATAGCTGGTTCTGTTTTAGC TGGAATTTTTGTACTCATCAACCGCAAGATAAGGAACTAA |
| Reference |
(1) Dolezal P; Aili M; Tong J; Jiang JH; Marobbio CM; Lee SF; Schuelein R; Belluzzo S; Binova E; Mousnier A; Frankel G; Giannuzzi G; Palmieri F; Gabriel K; Naderer T; Hartland EL; Lithgow T (2012). Legionella pneumophila secretes a mitochondrial carrier protein during infection. PLoS Pathog. 8(1):e1002459. [PudMed:22241989]  
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| experimental literature |
| in silico analysis literature |