| Effector Protein ID: 52843027 |
 T4SS name [ID] | Dot/Icm [5] |
| Gene symbol | vipD |
| Locus tag | lpg2831 |
| Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
| Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 3202105..3203970 [+] |
| Product | VipD |
| Effector type | Protein |
| Descripton | VipD |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Vesicle trafficking |
| UniProt ID | Q5ZRP9 |
| KEGG ID | lpn:lpg2831 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | Patatin [PF01734], Evalue: 1e-29, Aligned region: 38..297 |
| Protein Sequence: 621 a.a. [Download] |
| >gi|52843027|ref|YP_096826.1| VipD [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MKLAEIMTKSRKLKRNLLEISKTEAGQYSVSAPEHKGLVLSGGGAKGISYLGMIQALQERGKIKNLTHVS GASAGAMTASILAVGMDIKDIKKLIEGLDITKLLDNSGVGFRARGDRFRNILDVIYMMQMKKHLESVQQP IPPEQQMNYGILKQKIALYEDKLSRAGIVINNVDDIINLTKSVKDLEKLDKALNSIPTELKGAKGEQLEN PRLTLGDLGRLRELLPEENKHLIKNLSVVVTNQTKHELERYSEDTTPQQSIAQVVQWSGAHPVLFVPGRN AKGEYIADGGILDNMPEIEGLDREEVLCVKAEAGTAFEDRVNKAKQSAMEAISWFKARMDSLVEATIGGK WLHATSSVLNREKVYYNIDNMIYINTGEVTTTNTSPTPEQRARAVKNGYDQTMQLLDSHKQTFDHPLMAI LYIGHDKLKDALIDEKSEKEIFEASAHAQAILHLQEQIVKEMNDGDYSSVQNYLDQIEDILTVDAKMDDI QKEKAFALCIKQVNFLSEGKLETYLNKVEAEAKAAAEPSWATKILNLLWAPIEWVVSLFKGPAQDFKVEV QPEPVKVSTSENQETVSNQKDINPAVEYRKIIAEVRREHTDPSPSLQEKERVGLSTTFGGH |
| - |
| Nucleotide Sequence: 1866 bp [Download] |
| >gi|52840256|ref|NC_002942.5|:3202105-3203970 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome TTGAAACTTGCTGAAATTATGACAAAAAGCCGTAAATTAAAAAGGAATTTACTGGAAATATCAAAGACTG AGGCAGGACAATATTCTGTTAGTGCGCCTGAGCACAAAGGGTTGGTGCTAAGTGGCGGCGGAGCGAAAGG CATATCCTATTTGGGTATGATTCAAGCCTTACAAGAGCGCGGAAAAATAAAAAATCTGACCCATGTTAGC GGAGCATCTGCCGGAGCAATGACGGCGAGTATATTAGCCGTTGGCATGGATATCAAAGACATCAAAAAAC TGATTGAGGGATTGGACATCACCAAGCTATTAGATAATAGCGGAGTAGGTTTTCGTGCGAGAGGAGATCG TTTTCGTAACATTCTGGATGTCATTTACATGATGCAAATGAAAAAACATTTAGAAAGCGTGCAGCAACCC ATTCCTCCAGAACAACAGATGAATTATGGCATACTTAAACAAAAAATAGCTCTCTATGAAGACAAGTTAT CAAGAGCAGGGATTGTGATAAATAATGTAGACGATATTATCAACTTGACAAAATCAGTAAAAGATTTGGA AAAACTTGATAAAGCACTTAATAGTATTCCTACTGAGTTGAAAGGCGCCAAAGGAGAACAACTTGAAAAT CCTCGTCTAACTCTTGGTGACTTGGGCCGCTTAAGAGAGTTGCTGCCTGAGGAAAATAAACATCTAATTA AAAACTTGTCTGTAGTTGTAACTAATCAAACAAAGCATGAGCTGGAACGCTACAGTGAAGACACAACTCC TCAACAATCTATAGCACAAGTTGTCCAGTGGTCTGGGGCCCATCCGGTACTTTTCGTACCTGGCAGAAAT GCCAAGGGTGAATACATCGCTGATGGAGGAATTCTGGACAATATGCCGGAAATTGAAGGGCTTGACAGAG AAGAGGTGCTTTGTGTCAAAGCAGAGGCAGGCACCGCATTTGAAGATCGCGTTAATAAGGCCAAGCAAAG TGCTATGGAAGCGATAAGCTGGTTTAAGGCACGCATGGATTCTTTGGTTGAGGCTACAATAGGTGGAAAA TGGCTTCATGCCACTTCATCCGTGTTAAATCGTGAAAAAGTCTATTATAACATTGATAATATGATTTACA TTAATACAGGGGAAGTCACAACCACAAACACCTCTCCAACACCTGAACAAAGAGCGCGCGCTGTAAAAAA TGGCTACGATCAGACAATGCAATTACTGGATTCTCACAAGCAAACATTTGATCATCCATTAATGGCAATA CTTTATATCGGACATGATAAACTCAAGGATGCATTGATTGATGAGAAATCAGAGAAAGAGATTTTTGAGG CATCAGCGCATGCACAAGCTATTTTGCATCTTCAAGAACAAATCGTCAAAGAAATGAATGATGGTGATTA CAGTAGCGTGCAAAATTATTTAGATCAAATTGAAGACATTCTGACAGTCGATGCCAAAATGGATGACATC CAGAAAGAGAAGGCCTTTGCCCTCTGCATTAAACAAGTTAATTTTTTAAGTGAAGGAAAACTGGAAACTT ACTTGAATAAAGTTGAGGCAGAAGCTAAAGCAGCCGCTGAGCCTAGCTGGGCCACAAAGATATTGAATCT TCTTTGGGCACCAATTGAATGGGTTGTTTCCCTGTTCAAAGGCCCTGCCCAAGACTTTAAAGTTGAAGTT CAACCTGAACCGGTTAAGGTTTCTACCTCTGAAAATCAGGAAACAGTCTCTAATCAAAAGGATATCAATC CTGCCGTAGAGTATAGAAAAATCATAGCTGAAGTAAGGCGCGAGCATACCGATCCATCCCCATCCCTGCA AGAAAAAGAAAGGGTTGGTCTTTCAACCACATTTGGCGGCCATTAA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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(2) Burstein D; Zusman T; Degtyar E; Viner R; Segal G; Pupko T (2009). Genome-scale identification of Legionella pneumophila effectors using a machine learning approach. PLoS Pathog. 5(7):e1000508. [PudMed:19593377] 
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| experimental literature |
| in silico analysis literature |