| Effector Protein ID: 52843022 |
 T4SS name [ID] | Dot/Icm [5] |
| Gene symbol | - |
| Locus tag | lpg2826 |
| Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
| Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 3189788..3191521 [-] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | Ceg34 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Unknown |
| UniProt ID | Q5ZRQ4 |
| KEGG ID | lpn:lpg2826 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | Peptidase_C26 [PF07722], Evalue: 3.5e-21, Aligned region: 69..182 Peptidase_C26 [PF07722], Evalue: 3.5e-21, Aligned region: 294..343 GATase [PF00117], Evalue: 5.7e-12, Aligned region: 117..165 GATase [PF00117], Evalue: 5.7e-12, Aligned region: 293..347 |
| Protein Sequence: 577 a.a. [Download] |
| >gi|52843022|ref|YP_096821.1| hypothetical protein lpg2826 [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MLMIMARVIVTYSPEVGGSSVLSLKESFTHVGSEVIDGDYRKMMEDIPKEEFDKLYSTKEGRQRLFAHAK AKAMELLKNVDVLALSGNNSMIDPELFNQTRDPDQNYDFSRTIAELALVHVATEKGMPILGVCGGHQVIA VYGGGEICDLNSDKLNTQKVMNYDAIKVHKGSLIAQIIGGKQVQKEMDTARKAFNERMNQYNRLSEKLNA LEKLNLVQEAGKLDALGKLEELDKSEVQLLLKLTGLNIEEELFDLRELVGEIGETNQLKTELQNIKTSLN GLEDSHPLTSPHYETEFFGAHEQVVSKLAAGFQHTGTASDNESNEAAESEFGVPIITTQFHPEVGAKGLP EAHFFYLRTEAEQEMNLNIFRYLDKAGDAYNKKKNLMVELKQINPKNQDVLLQPSQIKKTSKERQQEREK QGNKSSSKRQTESYFFESILSKIGSYLSAIGEFIREGIGKFLRDILSSMFTYDSVSRLKKKEQKQSKSEH SKIDLIDSKSNSYSTVFHDMKVKSPSEILRENPAKLWAEKDDSHEKTITNQTDMDNSNKVRITTELVQEE VGQEFDENHTSLYRNNL |
| - |
| Nucleotide Sequence: 1734 bp [Download] |
| >gi|52840256|ref|NC_002942.5|:c3191521-3189788 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome ATGCTTATGATCATGGCAAGAGTAATTGTTACCTATAGTCCTGAAGTTGGTGGAAGCAGTGTTCTTTCGT TGAAAGAATCATTTACACATGTCGGTTCCGAAGTTATTGACGGCGACTACAGGAAAATGATGGAAGACAT ACCCAAAGAAGAATTTGATAAGTTGTATTCCACTAAAGAAGGCCGACAAAGATTATTTGCACACGCCAAA GCAAAAGCAATGGAATTACTTAAAAATGTTGATGTGTTAGCATTATCTGGTAATAATTCAATGATTGATC CTGAGCTTTTTAATCAAACAAGAGACCCCGATCAAAATTATGATTTTTCCAGAACAATTGCTGAATTGGC ATTAGTGCATGTAGCGACAGAAAAAGGTATGCCTATTCTAGGTGTTTGTGGTGGGCATCAAGTCATTGCA GTATATGGCGGTGGAGAAATATGCGATTTAAATTCTGACAAATTAAATACACAAAAAGTCATGAATTATG ATGCAATCAAAGTGCATAAGGGTTCATTAATAGCTCAAATTATTGGTGGAAAACAAGTCCAGAAAGAAAT GGATACAGCCAGAAAAGCGTTTAATGAAAGAATGAACCAATATAATAGATTGTCAGAAAAACTAAATGCA TTGGAAAAATTAAACCTAGTACAGGAAGCAGGGAAATTAGATGCATTAGGAAAATTAGAAGAGTTAGATA AATCTGAAGTGCAACTTTTATTAAAGTTGACTGGATTAAATATAGAAGAGGAGTTGTTTGATTTAAGAGA ATTAGTAGGAGAAATAGGCGAGACTAATCAATTAAAAACAGAACTACAAAATATAAAAACGAGTTTAAAT GGATTAGAAGATTCTCATCCTCTTACTTCCCCGCATTATGAAACGGAGTTTTTTGGCGCGCATGAGCAAG TTGTTTCCAAATTAGCAGCAGGCTTTCAACATACAGGTACTGCAAGTGATAATGAGTCCAATGAAGCAGC AGAATCAGAGTTTGGTGTTCCTATTATAACCACGCAATTCCATCCCGAAGTTGGTGCTAAAGGACTGCCC GAGGCTCATTTCTTTTATCTAAGAACAGAAGCTGAACAAGAGATGAATCTTAATATATTTAGATACCTTG ACAAAGCAGGTGATGCTTACAATAAAAAGAAAAACCTAATGGTTGAGCTAAAACAAATCAATCCGAAAAA TCAAGATGTATTGCTTCAACCCTCTCAAATTAAAAAAACAAGCAAAGAACGTCAGCAAGAGAGGGAAAAA CAAGGGAACAAGTCTTCATCAAAAAGACAAACAGAATCTTACTTTTTTGAGAGTATACTCTCAAAAATTG GTTCATATTTAAGTGCCATAGGAGAATTCATAAGAGAAGGAATTGGTAAATTTTTAAGAGACATCCTATC AAGTATGTTTACATATGATTCCGTTTCAAGACTGAAAAAAAAGGAACAAAAACAATCAAAATCTGAGCAT TCGAAAATAGATCTCATTGATAGCAAAAGTAACTCATATTCTACTGTGTTTCATGATATGAAAGTTAAGT CACCTTCTGAAATATTACGAGAAAATCCAGCAAAGTTGTGGGCAGAAAAAGATGATAGTCATGAGAAAAC CATCACCAATCAAACTGACATGGATAACTCTAATAAGGTAAGAATAACAACAGAATTGGTTCAAGAAGAA GTTGGACAAGAGTTTGATGAGAACCATACTAGTTTGTACAGAAACAATTTATAA |
| Reference |
(1) Lévesque S et al. (2014). Genomic characterization of a large outbreak of Legionella pneumophila serogroup 1 strains in Quebec City, 2012. PLoS One. 9(8):e103852. [PudMed:25105285] 
|
(2) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
|
|
(3) Burstein D; Zusman T; Degtyar E; Viner R; Segal G; Pupko T (2009). Genome-scale identification of Legionella pneumophila effectors using a machine learning approach. PLoS Pathog. 5(7):e1000508. [PudMed:19593377]
|
| experimental literature |
| in silico analysis literature |