SecReT4
Effector Protein ID: 52842948
T4SS name [ID]Dot/Icm [5]
Gene symbol-
Locus taglpg2744
StrainLegionella pneumophila subsp. pneumophila str. Philadelphia 1
Repliconchromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon]
Location [Strand]3094245..3095414 [-]
Producthypothetical protein
Effector typeProtein
Descriptonlpg2744
T4CP requirementT4CP Depedent
Target/EffectionUnknown
UniProt IDQ5ZRX7
KEGG IDlpn:lpg2744
PDB IDNA
Domain hit(s) vs Pfam NA
Protein Sequence: 389 a.a.     [Download]
>gi|52842948|ref|YP_096747.1| hypothetical protein lpg2744 [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
MSNLIELALRNAALDRTKLLSQVQKIEFLNGYDPRFVEGLISLEMIGDIDEYVASLMYVKMTDKYTQEEK
EQLTDTILTINNDRLISCQYRFPQLYQKLMQDQFLSTFFSSSHLLPNIAPGTNNQSYETVSTNNKMKMES
AKLYGHYEYYQCVVALITQIDGSRYFYHLNPNRIFGDYMGSAPLKLSGSELKDVKDITFILHPRSMVDYR
EFQRLQERNIVFKTVMLPVGAKSVSLSYDTDKDVLTVNNLEAGQTVTYNNLLQTPQYNRYQYTPEQYFMT
QLYRGQTWAEALGEALDKYIVTRQEGATWWDLKPLFFNRKTTKNNMIAAARIKKEIEAGATSFDFTGVSR
NGLLNQLLTTAVDYQLEYQRGLQNGVLSAEDLTTSAALR
-
Nucleotide Sequence: 1170 bp     [Download]
>gi|52840256|ref|NC_002942.5|:c3095414-3094245 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome
ATGTCAAATCTAATAGAACTTGCTTTAAGAAACGCGGCACTTGATAGAACAAAACTTTTAAGTCAGGTAC
AAAAAATTGAATTTTTAAATGGTTATGATCCCAGGTTTGTCGAGGGATTGATATCATTAGAAATGATAGG
CGATATTGATGAATACGTTGCTTCTTTGATGTATGTTAAAATGACTGATAAATACACTCAGGAGGAAAAA
GAGCAATTAACAGATACTATATTAACCATCAATAATGATCGATTGATTTCATGCCAATATCGCTTTCCTC
AATTATATCAAAAATTAATGCAAGACCAATTTTTATCTACTTTCTTTTCAAGTTCGCATTTGCTCCCCAA
TATTGCTCCAGGCACAAATAATCAATCTTATGAAACAGTAAGTACTAATAATAAAATGAAGATGGAGTCA
GCAAAGTTATATGGGCATTATGAATATTATCAATGTGTTGTCGCTTTAATCACTCAAATTGATGGTTCTC
GATATTTTTATCATTTGAATCCAAACCGTATCTTTGGTGATTACATGGGTAGTGCGCCTTTGAAATTATC
AGGTAGTGAACTTAAAGATGTAAAGGATATAACCTTTATCCTTCACCCGCGAAGTATGGTTGATTATCGC
GAATTTCAAAGATTACAAGAGAGAAATATTGTTTTTAAAACCGTTATGCTACCAGTGGGGGCAAAGTCGG
TATCACTTAGTTATGATACAGATAAAGATGTATTGACGGTTAACAATCTTGAGGCAGGACAAACTGTAAC
ATATAACAATCTGCTACAAACACCCCAATATAATAGATATCAATATACACCTGAGCAATATTTCATGACC
CAACTATATAGAGGCCAAACATGGGCAGAAGCACTTGGCGAGGCATTGGATAAATATATTGTTACAAGAC
AAGAAGGAGCAACCTGGTGGGATCTTAAACCATTATTTTTTAATCGTAAGACTACAAAAAATAATATGAT
TGCTGCTGCGCGGATCAAAAAGGAAATTGAGGCTGGTGCTACCTCATTTGATTTTACAGGGGTTAGCAGG
AATGGCTTGCTTAATCAATTATTAACAACTGCTGTTGACTATCAATTAGAATACCAGCGTGGATTGCAAA
ACGGGGTGCTTTCGGCTGAAGACCTAACAACAAGTGCTGCGTTACGTTGA

Reference
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] in_silico
(2) Burstein D; Zusman T; Degtyar E; Viner R; Segal G; Pupko T (2009). Genome-scale identification of Legionella pneumophila effectors using a machine learning approach. PLoS Pathog. 5(7):e1000508. [PudMed:19593377] experimental in_silico
(3) Kubori T; Hyakutake A; Nagai H (2008). Legionella translocates an E3 ubiquitin ligase that has multiple U-boxes with distinct functions. Mol Microbiol. 67(6):1307-19. [PudMed:18284575] experimental
 
experimental experimental literature
in_silico in silico analysis literature