| Effector Protein ID: 52842764 |
 T4SS name [ID] | Dot/Icm [5] |
| Gene symbol | legK3 |
| Locus tag | lpg2556 |
| Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
| Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2890013..2891401 [+] |
| Product | protein kinase |
| Effector type | Protein |
| Descripton | LegK3 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Unknown |
| UniProt ID | Q5ZSG1 |
| KEGG ID | lpn:lpg2556 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | Pkinase [PF00069], Evalue: 2.4e-25, Aligned region: 50..311 Pkinase_Tyr [PF07714], Evalue: 1.5e-11, Aligned region: 50..309 |
| Protein Sequence: 462 a.a. [Download] |
| >gi|52842764|ref|YP_096563.1| protein kinase [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MFDRNIKEIINELQEKDLLPDTGKIIGGPRNQFDKKGEIKQGYLFSVMNKEPIGKGGFASVYPVTLYRQG ETGFAKKSTDHKKFVTKKFNLNKLKIKYTNLNIENLIEKEFEFCRKAGHLSIKPPVYNNNKCYLTMKRMP GMDLNRIFNKLMANPHYLTEGQRIKITYALLLALKNQVIDKGIIHRDIKPENIHVKVVDPVEVNIFDYGL AKNAGEDDNLFPGSESWAAPEMFIGLKHDSKADIFSMGRVIAFLWGESATNYLSNNPLNKSRNAAKNLNL PAQVKWVEPFLKQMLAERQEDRIEIDSAINQFKQLASINAPKLKLPQSSIKNHSNINNLCFFQNPTKSTN NSDLTQLNIQRDIKKDLQELLENLPGEFSHYRSNIIFKNTIGRFTTIQKMMNELNRIMDENESQDIPKEL YDFIHQYQNKFLHASEANIIRKINGFLEDIEYQNLTNSGFEL |
| - |
| Nucleotide Sequence: 1389 bp [Download] |
| >gi|52840256|ref|NC_002942.5|:2890013-2891401 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome ATGTTTGATAGAAATATAAAAGAAATAATCAATGAATTACAAGAAAAGGATTTACTTCCGGACACTGGAA AAATTATCGGCGGACCCCGAAATCAATTTGATAAGAAAGGAGAGATAAAACAAGGGTATCTTTTTTCAGT TATGAACAAAGAACCAATAGGAAAAGGTGGGTTCGCTTCTGTTTATCCTGTTACGCTGTATCGGCAAGGT GAAACTGGATTTGCTAAAAAATCTACTGATCATAAGAAGTTTGTAACAAAGAAATTTAATTTAAATAAAC TTAAAATAAAATACACCAACTTAAATATAGAAAATTTAATTGAAAAAGAGTTTGAGTTTTGTCGAAAAGC AGGGCACTTAAGTATAAAACCACCTGTTTACAATAATAATAAATGTTATCTAACGATGAAACGAATGCCA GGGATGGATTTAAATCGTATCTTCAATAAATTAATGGCTAATCCTCATTATCTTACAGAGGGTCAACGAA TTAAGATAACCTATGCTTTATTATTGGCTTTGAAAAATCAGGTGATTGATAAAGGAATTATTCATCGAGA TATAAAGCCTGAGAATATTCATGTTAAAGTGGTTGACCCTGTTGAAGTGAATATTTTCGATTACGGACTT GCCAAAAATGCAGGCGAAGACGATAACCTATTTCCTGGAAGTGAAAGTTGGGCAGCGCCTGAAATGTTTA TTGGCTTAAAGCACGATAGTAAAGCTGATATTTTTTCAATGGGAAGAGTGATTGCCTTCTTATGGGGCGA AAGTGCTACAAACTATTTGAGTAATAACCCCCTTAATAAAAGCCGAAATGCAGCAAAAAACCTTAATTTG CCCGCACAAGTTAAATGGGTAGAGCCATTTTTGAAACAAATGTTAGCGGAAAGACAAGAGGATAGAATAG AGATTGATTCCGCAATAAACCAATTTAAGCAACTTGCGTCCATTAACGCGCCGAAGCTTAAATTACCTCA ATCCTCAATAAAGAATCACTCAAATATTAATAATCTCTGCTTTTTTCAAAATCCAACTAAAAGCACAAAC AATTCTGATCTTACACAATTAAATATTCAGCGGGATATCAAAAAGGATTTGCAGGAATTATTAGAGAATC TTCCTGGTGAATTTTCTCATTATCGCAGTAATATAATTTTTAAAAACACAATAGGCCGTTTTACAACAAT ACAAAAAATGATGAATGAACTAAATCGGATCATGGATGAAAACGAATCTCAAGATATACCCAAGGAATTA TATGATTTTATTCATCAATATCAGAATAAATTTTTGCATGCAAGCGAAGCTAATATTATAAGAAAAATAA ATGGCTTCTTAGAAGATATAGAGTATCAAAATTTAACCAATTCAGGCTTTGAATTATAA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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(2) Burstein D; Zusman T; Degtyar E; Viner R; Segal G; Pupko T (2009). Genome-scale identification of Legionella pneumophila effectors using a machine learning approach. PLoS Pathog. 5(7):e1000508. [PudMed:19593377] 
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| experimental literature |
| in silico analysis literature |