| Effector Protein ID: 52842733 |
 T4SS name [ID] | Dot/Icm [5] |
| Gene symbol | - |
| Locus tag | lpg2525 |
| Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
| Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2852975..2854309 [+] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | MavK |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Unknown |
| UniProt ID | Q5ZSJ2 |
| KEGG ID | lpn:lpg2525 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | F-box-like [PF12937], Evalue: 1.2e-11, Aligned region: 10..55 |
| Protein Sequence: 444 a.a. [Download] |
| >gi|52842733|ref|YP_096532.1| hypothetical protein lpg2525 [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MKEKYKKSLYIPNELLLEIFADKNLDIQNIIVVSMVCKLWYELSLDNAVWRPLFIKRFSYSPTLANHSIF KEDYQKQLALTQAMKKKCESNHACRNEPGLLEAIREKNIPLIYALFESGHRIIIDSFPDGEQQFTEEMLG FLSECAELPSSLLARIFKRGFCTADMETSEFLALHFIVAEADEKLLQKIFRALGDDLLSVSRYCDLYDNN FFSSLLHFPVERFSLVLRLLYETLGKTKLSTLLVYQNHTYTDWSCIHSASRCGREYFFITLKYLKRQDYP VLLKKGLNDEDIPLFNIAYWGDKESLSHIINILGADATTFLKYKDNKGRNILLPALLSEDHSTVELIEKV MGMEFIDLLLMQDTNGRDILRRVMLLQEPTVLRRINTVLKLLRDYDCLDIAQELYSSDEFTQLISQNLYI NQDETIELFNKYTEEKTNNFCSIL |
| - |
| Nucleotide Sequence: 1335 bp [Download] |
| >gi|52840256|ref|NC_002942.5|:2852975-2854309 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome ATGAAAGAAAAATACAAAAAGAGTCTATATATTCCAAATGAACTTCTTTTAGAAATTTTTGCGGATAAAA ATTTAGACATTCAAAATATCATAGTTGTCAGCATGGTTTGTAAACTTTGGTATGAGTTATCACTTGATAA TGCCGTTTGGAGGCCTTTATTTATCAAACGATTTTCCTATTCACCAACTTTAGCTAACCACTCAATCTTT AAAGAGGATTATCAAAAACAATTGGCTTTAACTCAAGCAATGAAAAAGAAATGTGAATCAAATCATGCAT GTAGGAATGAGCCAGGATTACTAGAGGCTATTAGAGAAAAAAACATTCCTTTGATCTACGCCTTATTTGA ATCTGGCCATCGAATTATCATAGATAGTTTTCCTGATGGCGAACAACAGTTTACTGAAGAAATGCTTGGT TTTTTATCAGAATGCGCTGAATTACCAAGTTCCTTATTGGCAAGAATTTTTAAACGTGGTTTTTGCACAG CAGACATGGAGACCAGTGAGTTTTTGGCATTACATTTCATTGTTGCAGAAGCTGATGAAAAACTATTACA AAAAATATTTAGAGCTCTAGGTGATGACTTATTATCAGTTAGCCGCTATTGTGATCTTTATGATAACAAT TTTTTTAGCTCTCTATTACATTTTCCTGTAGAACGATTTTCATTAGTACTGAGATTGCTCTACGAAACTT TAGGAAAAACAAAACTGAGTACTCTTTTAGTGTACCAAAACCATACTTACACTGATTGGAGTTGCATTCA TTCTGCAAGTAGATGTGGTAGAGAATATTTCTTCATTACTCTCAAATATCTTAAAAGGCAAGATTATCCT GTATTATTGAAAAAAGGATTAAATGATGAAGATATTCCTTTATTCAATATTGCATATTGGGGCGATAAAG AGTCTTTATCTCACATTATTAACATTTTGGGAGCTGACGCAACAACGTTTCTTAAATACAAGGACAATAA AGGACGTAACATCTTATTGCCCGCATTGTTGAGTGAAGATCATTCAACAGTTGAATTAATTGAAAAAGTG ATGGGGATGGAATTCATTGATTTGTTACTTATGCAAGATACAAATGGCCGCGATATTTTGAGACGAGTCA TGTTGCTTCAGGAACCTACAGTATTGAGACGCATCAATACAGTACTTAAACTATTACGTGATTATGATTG CCTGGACATTGCTCAGGAGCTATATAGCAGTGATGAATTTACCCAACTCATATCTCAGAATTTATATATC AACCAGGATGAAACCATAGAGTTATTCAATAAATATACAGAAGAAAAAACAAACAATTTTTGTTCTATTT TATAA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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(2) Ensminger AW et al. (2010). E3 ubiquitin ligase activity and targeting of BAT3 by multiple Legionella pneumophila translocated substrates. Infect Immun. 78(9):3905-19. [PudMed:20547746] 
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| experimental literature |
| in silico analysis literature |