| Effector Protein ID: 52842731 |
 T4SS name [ID] | Dot/Icm [5] |
| Gene symbol | - |
| Locus tag | lpg2523 |
| Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
| Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2849475..2851814 [+] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | Lem26 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Unknown |
| UniProt ID | Q5ZSJ4 |
| KEGG ID | lpn:lpg2523 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 779 a.a. [Download] |
| >gi|52842731|ref|YP_096530.1| hypothetical protein lpg2523 [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MKTKLNKSILFKQGNAGELFESFIQKVDENAKPNQLEEIIAVAKPQVIAPVTKNKYTKQFEIIVSALLTN KSNIVFTQNNGKYVVNVNGADFNLDEILANMQRSQINLSTEQLNQYVNYVDKEAGIKVTIPDAAKKPITL SCQELKGKATKLQHLHEGEIAGLNIYTQQYYEFMNGLLRGQHPYKGNDANFQENMRQVILHSAAALSGIS KGQKHKLPLTFRYDGDTLPKPIIEKRIQCAQSKGIGLEVYEDTAFVSSAFEKPVSTFNGPIRTVFYGMQG LDIGEISRYPAEREFLIAPGKVKYLHHREENKKHYFLACSVTPPASIKQISNLPNGGTYKQAENIAVEAE RDMVKKFAQFAIDVTNQYLEGKAEKDKSKWSILANIDNTYGKGSYKIQFAEELKTSLNGLLNNLQNGYIE HKAAHNRIIEILHQAIEKAQTIDNISLSYAKGQDSSGVLSKTLQYICFQVEDEMKGLETFKSSITEYFAG HQSFFESSRNIGVIDKLHKDYLSKPYDQSEKGKDPNGGDWTLNCGNNKTLHRPNHGLSHTLRGAALVPEV LYSYATHSTDKKTRDMVQNISKDDIKRMQVAMLFSVVGRKSELGFADNPGVYGGYRRASADLFEEYAKTH YKDLFTSKEQIAYWKRLVLDYGNPGFHPDVNKPEQAIIAKIMRQCHCLDLLRCYSKEEFTKKVTKPLQDD LGVDAANNLVNYSKTLLEKTGDRLIGTKSYNLQEHWLNNTDVSHCINTLNSALQHAPHQQYVVKHEEEES LDSDMWVKL |
| - |
| Nucleotide Sequence: 2340 bp [Download] |
| >gi|52840256|ref|NC_002942.5|:2849475-2851814 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome ATGAAAACCAAACTAAACAAATCAATCCTTTTTAAACAAGGAAATGCTGGTGAGCTTTTTGAGTCTTTTA TTCAAAAAGTTGATGAAAATGCCAAGCCTAATCAGCTTGAAGAAATTATCGCTGTTGCAAAACCCCAAGT CATAGCCCCAGTGACAAAAAATAAATACACTAAACAATTTGAAATTATAGTATCCGCTTTACTAACCAAT AAATCCAATATTGTCTTTACACAAAATAATGGCAAATATGTTGTAAATGTAAATGGGGCAGATTTCAATC TGGATGAAATCCTGGCTAACATGCAACGCTCTCAAATAAATCTGTCTACTGAACAACTAAATCAGTATGT TAATTACGTTGATAAAGAAGCAGGAATTAAAGTTACAATTCCAGATGCTGCGAAAAAACCAATAACTTTG AGTTGTCAAGAATTGAAAGGTAAAGCAACCAAATTACAACATCTTCATGAAGGTGAAATTGCTGGATTAA ATATATATACCCAACAATATTATGAATTTATGAATGGCTTATTAAGAGGCCAGCATCCATACAAAGGAAA CGATGCAAACTTTCAGGAAAATATGCGTCAGGTAATACTCCATAGCGCAGCAGCACTCTCAGGAATTAGT AAAGGTCAAAAGCATAAACTTCCATTGACCTTCCGATACGACGGAGACACCCTTCCCAAGCCTATTATTG AAAAAAGAATTCAATGCGCCCAGTCAAAAGGTATAGGACTAGAAGTTTATGAAGACACCGCTTTTGTCAG TAGTGCTTTTGAAAAACCTGTATCTACTTTTAATGGACCCATTCGAACCGTATTTTATGGTATGCAAGGA TTGGATATAGGAGAAATCTCTCGTTATCCTGCTGAGCGTGAATTTTTAATCGCTCCTGGTAAAGTCAAAT ACCTGCACCATCGAGAAGAAAATAAAAAACACTATTTCCTGGCGTGTTCCGTCACTCCTCCTGCAAGCAT AAAACAAATATCAAATTTGCCAAACGGGGGTACTTATAAACAAGCGGAAAACATAGCAGTCGAAGCAGAG AGGGATATGGTAAAAAAATTCGCACAATTTGCTATCGATGTAACAAATCAATATCTTGAAGGTAAGGCTG AAAAAGACAAAAGCAAATGGTCAATTTTAGCAAATATTGATAATACCTATGGAAAAGGCTCTTATAAAAT TCAATTTGCAGAAGAACTAAAAACATCATTGAATGGATTGCTGAATAATTTACAAAATGGGTATATTGAA CATAAAGCCGCTCACAACAGAATTATTGAAATACTTCATCAGGCCATTGAAAAAGCCCAAACTATAGATA ATATTTCTTTATCCTACGCAAAAGGGCAAGACAGTTCTGGAGTCCTTTCTAAAACCTTACAATACATCTG TTTTCAGGTTGAGGATGAAATGAAGGGATTAGAAACATTCAAAAGTTCAATCACTGAATATTTTGCCGGA CATCAAAGCTTTTTTGAAAGCTCCAGGAATATTGGAGTCATTGATAAGTTGCATAAAGACTATCTATCAA AACCATACGACCAATCAGAAAAAGGCAAAGACCCCAATGGTGGCGATTGGACTTTAAATTGTGGTAACAA TAAAACTCTTCATAGACCAAATCATGGGCTGTCTCACACTTTAAGAGGTGCTGCTCTAGTTCCAGAGGTA CTTTATTCCTACGCGACGCATTCCACCGATAAGAAGACCAGAGATATGGTTCAAAACATAAGCAAGGATG ACATCAAACGAATGCAAGTCGCCATGTTATTTTCTGTTGTCGGCAGAAAAAGCGAACTGGGATTTGCAGA TAACCCAGGAGTATATGGAGGATATAGAAGAGCCAGCGCAGACCTTTTTGAAGAGTATGCAAAAACGCAT TATAAAGACTTATTTACCTCAAAAGAGCAAATTGCCTATTGGAAACGCTTGGTACTTGATTATGGAAACC CTGGTTTTCATCCAGATGTGAACAAACCTGAACAAGCAATCATAGCTAAAATAATGAGACAATGCCATTG TCTGGATTTATTAAGATGCTATTCTAAAGAGGAATTCACGAAAAAGGTAACCAAACCGCTTCAAGATGAC TTGGGAGTTGACGCAGCTAATAATCTTGTCAACTACTCCAAAACCCTTCTTGAAAAAACAGGAGACAGAT TAATCGGTACGAAGAGCTACAATTTACAAGAACATTGGCTCAACAACACTGACGTATCACATTGCATCAA TACTCTGAACTCCGCTTTACAACACGCACCACACCAACAATATGTTGTTAAGCATGAGGAAGAGGAATCC TTAGATTCAGATATGTGGGTTAAACTATAA |
| Reference |
(1) Lévesque S et al. (2014). Genomic characterization of a large outbreak of Legionella pneumophila serogroup 1 strains in Quebec City, 2012. PLoS One. 9(8):e103852. [PudMed:25105285] 
|
(2) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
|
|
(3) Burstein D; Zusman T; Degtyar E; Viner R; Segal G; Pupko T (2009). Genome-scale identification of Legionella pneumophila effectors using a machine learning approach. PLoS Pathog. 5(7):e1000508. [PudMed:19593377]
|
| experimental literature |
| in silico analysis literature |