| Effector Protein ID: 52842717 |
 T4SS name [ID] | Dot/Icm [5] |
| Gene symbol | - |
| Locus tag | lpg2509 |
| Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
| Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2829940..2831133 [-] |
| Product | protein SdeD |
| Effector type | Protein |
| Descripton | SdeD |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Unknown |
| UniProt ID | Q5ZSK8 |
| KEGG ID | lpn:lpg2509 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | SidE [PF12252], Evalue: 4e-35, Aligned region: 20..274 |
| Protein Sequence: 397 a.a. [Download] |
| >gi|52842717|ref|YP_096516.1| protein SdeD [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MLYNKSSFCLWKETIVPIILDSDVLEVAEYVYKTRLSQPYTEVGSEWEYNYKNPTATFAKGDGHNLQRYI TIDGKQLHRPIHGLAHTMRTLMYSQLMYCSSKKQPSPHVCQDGRTIADLSELDLKKINIAQLFFVAGRES EASYGDAYHRYHLYGAKQFEEYARKHLTHLFSEEEIRLYSRCIEDRVGDSFDGTPEGYIIHLSHMIDLMR CKSPVEVFLGHSKGVSGIVPTLIHLFGKQDGLDIMHYARGLFAATGEAVPYIDSSEWPHLGVDLSRVQRA LSIVGDINVPGQEADSKKTAQAGFSVDGCYSALTSVPTPSWYEKELKEIDDEKIDVKEVDDREIEKEHEI VVPSQATTPLSTVKTDSFVEKLLKPFMIWKKPEVQTTQPTTEKTNKP |
| - |
| Nucleotide Sequence: 1194 bp [Download] |
| >gi|52840256|ref|NC_002942.5|:c2831133-2829940 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome TTGTTATATAATAAATCCTCATTTTGTTTATGGAAGGAGACCATTGTGCCTATTATTCTAGATTCTGATG TGTTGGAAGTGGCGGAATATGTGTATAAAACACGCTTATCTCAGCCTTACACTGAAGTGGGTTCTGAATG GGAGTATAATTACAAGAATCCAACAGCCACTTTTGCAAAAGGCGATGGCCATAACTTGCAAAGGTATATT ACAATTGATGGCAAGCAGCTTCATCGCCCTATCCATGGGTTAGCTCATACGATGCGCACATTGATGTATA GCCAATTGATGTATTGCTCCTCAAAAAAACAACCTTCCCCACACGTATGTCAAGACGGACGAACAATAGC CGATCTCAGTGAACTTGATCTTAAAAAGATAAACATTGCGCAGCTATTTTTTGTAGCCGGGCGCGAAAGC GAGGCTTCTTATGGTGATGCTTATCATCGTTATCATCTGTATGGGGCTAAACAGTTCGAAGAATATGCCC GCAAGCATTTGACTCATCTTTTTTCAGAAGAAGAAATCCGATTGTACTCACGATGTATAGAAGACAGGGT AGGTGACAGTTTTGATGGTACCCCTGAAGGTTATATAATTCACTTGTCACACATGATCGATTTGATGCGT TGCAAAAGCCCGGTTGAAGTATTTTTGGGCCACTCAAAAGGGGTTTCTGGTATTGTACCTACATTGATTC ACTTGTTTGGCAAACAAGATGGCTTGGATATTATGCATTACGCCCGAGGCTTGTTTGCGGCTACAGGTGA GGCGGTGCCCTATATTGATTCATCTGAATGGCCTCATTTGGGAGTTGACTTGAGTCGGGTACAACGCGCA CTCTCTATCGTTGGTGATATCAATGTCCCTGGGCAAGAGGCTGATTCTAAAAAAACAGCGCAAGCCGGTT TTTCTGTGGATGGTTGTTATTCTGCGTTAACCAGTGTGCCTACACCTTCCTGGTATGAGAAAGAGTTAAA AGAAATCGATGATGAAAAAATCGATGTTAAGGAAGTTGATGATAGGGAGATAGAAAAAGAACATGAGATA GTTGTTCCTTCGCAGGCAACAACACCTTTAAGTACAGTAAAAACTGACTCCTTTGTCGAAAAACTTCTGA AGCCATTTATGATTTGGAAAAAGCCAGAGGTACAAACGACTCAACCAACAACGGAGAAGACTAATAAACC TTAG |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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(2) Burstein D; Zusman T; Degtyar E; Viner R; Segal G; Pupko T (2009). Genome-scale identification of Legionella pneumophila effectors using a machine learning approach. PLoS Pathog. 5(7):e1000508. [PudMed:19593377] 
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(3) Tiaden A; Spirig T; Carranza P; Bruggemann H; Riedel K; Eberl L; Buchrieser C; Hilbi H (2008). Synergistic contribution of the Legionella pneumophila lqs genes to pathogen-host interactions. J Bacteriol. 190(22):7532-47. [PudMed:18805977]
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| experimental literature |
| in silico analysis literature |