| Effector Protein ID: 52842663 |
 T4SS name [ID] | Dot/Icm [5] |
| Gene symbol | - |
| Locus tag | lpg2455 |
| Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
| Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2769090..2769719 [+] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | GobX |
| T4CP requirement | T4CP Depedent |
| Target/Effection | GobX exploits two post translational modification pathways of host cells, ubiquitina tion and S-palmitoylation. |
| UniProt ID | Q5ZSR2 |
| KEGG ID | lpn:lpg2455 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 209 a.a. [Download] |
| >gi|52842663|ref|YP_096462.1| hypothetical protein lpg2455 [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MTKIVYLHNDPDKMLYYKDSVPKDLKVVEPDAKMMLEILEQKLKLLEVVDLDWFYCAICMELPKEPVFYP TSEGISNLYEKSELVKWFSRDPRNKSDPVGLGLNVTISQYKTPTPKELLDFVIKSTGFAEEVFIDHYKKP LAKKISPEEELLLEKPDNTRRNEIDSPTHSQSRSCWSLFLYSIFGGKDNRKVMQEKTDSLTSYDIQPHH |
| - |
| Nucleotide Sequence: 630 bp [Download] |
| >gi|52840256|ref|NC_002942.5|:2769090-2769719 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome ATGACGAAAATTGTTTATCTACACAATGACCCGGATAAAATGCTCTATTATAAGGACAGCGTTCCCAAAG ATTTAAAAGTGGTTGAACCAGATGCCAAAATGATGTTAGAAATTTTAGAGCAAAAATTAAAACTACTCGA AGTAGTTGATTTAGATTGGTTTTATTGTGCAATTTGTATGGAACTTCCTAAAGAGCCAGTGTTTTATCCA ACCTCAGAAGGCATTAGTAATCTTTACGAAAAAAGTGAATTAGTCAAATGGTTTTCAAGAGACCCCAGAA ATAAATCCGACCCCGTTGGACTTGGTTTAAATGTTACTATATCTCAATATAAAACTCCTACTCCAAAAGA ATTGCTTGATTTTGTTATTAAATCAACAGGATTTGCTGAAGAGGTGTTCATTGACCATTACAAAAAACCA CTAGCAAAAAAAATTTCCCCTGAGGAAGAGCTCTTACTTGAGAAACCCGATAATACCAGACGCAATGAAA TAGATAGCCCCACTCATTCACAGTCAAGATCCTGCTGGAGTCTCTTTTTGTATAGTATTTTTGGTGGTAA AGATAACAGAAAAGTAATGCAGGAAAAAACTGATTCCCTAACATCGTATGATATACAGCCCCATCATTAA |
| Reference |
(1) Lin YH et al. (2015). Host Cell-catalyzed S-Palmitoylation Mediates Golgi Targeting of the Legionella Ubiquitin Ligase GobX. Biol Chem. 290(42):25766-81. [PudMed:26316537] 
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| experimental literature |