| Effector Protein ID: 52842619 |
 T4SS name [ID] | Dot/Icm [5] |
| Gene symbol | - |
| Locus tag | lpg2410 |
| Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
| Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2721767..2723764 [+] |
| Product | patatin-like phospholipase |
| Effector type | Protein |
| Descripton | VpdA |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Unknown |
| UniProt ID | Q5ZSV6 |
| KEGG ID | lpn:lpg2410 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | Patatin [PF01734], Evalue: 2.1e-24, Aligned region: 57..272 |
| Protein Sequence: 665 a.a. [Download] |
| >gi|52842619|ref|YP_096418.1| patatin-like phospholipase [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MKTKQEVSQQDKLKDSKSSTPLQTKEPWFISDTLNITFDSYDFSISVTEQAPIPSRIVFSGGGSRILAHI GALDELTRHGLKFTEFSGSSAGAMVAAFAYLGYNCSEIKQIISWFNEDKLLDSPLIFNFNNIKQIFNKGG LSSAKLMRQAANYVILKKVMDIISDEKFKTRFAKFQNFLEENIYSCPENITFQTLARIKEICPECELGEK LFITGTNLSTQKHEVFSIDTTPSMALADAIIISANLPIAFERICYQGNVYSDGGISNNLPAHCFSEKGHK TTFLKHKDDVDFSVLALQFDNGLEENALYSQNPIPKWSWLSNTFYSLITGHPNVTENWHEDLQILRRHAH QSILIKTPTIALTNLTISQDTKKALVESGRTAAKTYLELHEFYTDDYGNIRHNECLHEKFQKPEELLDYC VLHSHFALLKKIKQAISCSQYLEKGYKHYLCELCDNLLPPQLKCPNEGSGTEQPEIKLEKDTIICKKNNN SGLTFSMTFFGVPSPLGKTLNQDSPELKIKLFTGLYPILIQNWQNLCPVSGISGILNSIRMSFVEISSTD TCIKTLIDKLNEIEIGHFLIFVFKAALKNYDKHDFILLLKNLKHLHHSIELIRNKPFHSDDRFYGQWSFE GHDPKRILEFIKSDDISGLMTILEDKKALPNNKPN |
| - |
| Nucleotide Sequence: 1998 bp [Download] |
| >gi|52840256|ref|NC_002942.5|:2721767-2723764 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome ATGAAAACAAAGCAAGAAGTTTCTCAGCAGGATAAATTAAAAGATTCAAAATCGTCTACACCACTACAGA CAAAAGAACCATGGTTCATCTCTGATACCTTAAATATTACTTTTGACTCCTATGATTTTAGTATCTCTGT CACTGAACAAGCCCCCATACCCTCTCGTATTGTTTTCAGTGGTGGAGGTTCAAGAATACTGGCACACATA GGTGCCCTAGATGAGTTAACCAGGCATGGATTAAAGTTCACTGAATTTTCCGGAAGCTCAGCCGGTGCAA TGGTCGCTGCCTTTGCTTATCTTGGTTATAATTGTTCCGAAATAAAACAAATTATTTCCTGGTTTAATGA AGATAAACTCCTTGATAGCCCACTCATTTTTAATTTCAATAACATAAAACAAATATTTAACAAGGGGGGG CTTAGCTCGGCAAAATTAATGCGTCAAGCAGCAAATTACGTTATTTTAAAAAAAGTAATGGATATTATAT CCGATGAAAAATTCAAAACACGATTTGCAAAATTTCAAAATTTTTTAGAAGAAAATATATACAGCTGCCC CGAGAATATAACATTTCAAACCTTAGCCAGAATAAAAGAAATATGTCCTGAATGTGAATTAGGAGAAAAA CTATTTATTACTGGAACAAATTTGAGTACCCAAAAACATGAAGTGTTTTCTATTGATACAACACCATCTA TGGCACTTGCCGATGCCATTATTATTTCCGCAAATTTACCTATTGCCTTTGAGCGTATCTGCTATCAAGG AAACGTATACAGCGATGGAGGAATCAGCAATAATTTACCTGCCCATTGTTTTTCAGAAAAAGGGCATAAA ACAACCTTTTTGAAACACAAAGATGATGTTGACTTCAGTGTACTTGCTCTGCAGTTTGATAATGGGCTTG AAGAGAACGCTCTTTATAGCCAGAACCCAATACCTAAATGGTCATGGCTAAGCAACACATTCTACTCATT GATTACAGGACATCCAAATGTTACTGAAAACTGGCATGAGGATCTTCAAATACTGAGGCGACATGCCCAT CAAAGTATTTTAATTAAAACGCCAACTATTGCTTTGACCAATCTCACAATTAGTCAAGATACAAAAAAAG CCCTGGTCGAATCAGGACGAACAGCTGCCAAGACCTATCTGGAACTCCATGAGTTTTATACGGATGATTA TGGAAATATCAGACATAATGAATGCTTGCATGAAAAATTTCAAAAACCCGAAGAGTTATTGGATTATTGT GTCCTACACAGCCACTTTGCACTTTTAAAAAAAATAAAGCAAGCCATTTCCTGCTCACAATATTTAGAAA AAGGGTATAAACATTATTTATGTGAGTTGTGTGACAACTTGCTTCCACCTCAACTGAAATGCCCCAACGA AGGTTCAGGAACAGAACAACCTGAAATCAAGTTAGAAAAAGATACCATCATTTGCAAAAAGAATAATAAT AGTGGGCTGACATTTTCAATGACATTTTTTGGGGTTCCATCCCCTTTAGGCAAAACATTAAATCAGGATA GCCCAGAATTAAAAATTAAGCTATTTACAGGTTTATATCCTATACTAATTCAAAACTGGCAAAATTTATG CCCTGTTTCAGGCATTAGTGGTATATTAAATTCTATCCGCATGTCATTCGTTGAAATCAGTTCAACAGAT ACCTGTATAAAAACATTAATTGATAAACTGAACGAAATTGAAATTGGACATTTTTTGATATTTGTTTTTA AAGCAGCTTTAAAAAATTACGATAAACATGACTTCATATTACTATTGAAAAACCTGAAGCATCTTCATCA TTCTATCGAGTTAATTAGAAATAAACCGTTTCATTCTGACGACCGATTTTATGGACAGTGGAGTTTTGAA GGGCATGATCCCAAAAGAATCCTCGAATTCATTAAAAGCGATGATATTTCAGGATTAATGACTATTTTAG AAGATAAAAAGGCGCTGCCCAATAATAAACCGAATTAA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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(2) Burstein D; Zusman T; Degtyar E; Viner R; Segal G; Pupko T (2009). Genome-scale identification of Legionella pneumophila effectors using a machine learning approach. PLoS Pathog. 5(7):e1000508. [PudMed:19593377] 
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| experimental literature |
| in silico analysis literature |