| Effector Protein ID: 52842609 |
 T4SS name [ID] | Dot/Icm [5] |
| Gene symbol | legL7 |
| Locus tag | lpg2400 |
| Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
| Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2711277..2712341 [+] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | LegL6 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Unknown |
| UniProt ID | Q5ZSW6 |
| KEGG ID | lpn:lpg2400 |
| PDB ID | 3GOZ |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 354 a.a. [Download] |
| >gi|52842609|ref|YP_096408.1| hypothetical protein lpg2400 [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MNYKLTLHPGSNPVEEFTSIPHGVTSLDLSLNNLYSISTVELIQAFANTPASVTSLNLSGNSLGFKNSDE LVQILAAIPANVTSLNLSGNFLSYKSSDELVKTLAAIPFTITVLDLGWNDFSSKSSSEFKQAFSNLPASI TSLNLRGNDLGIKSSDELIQILAAIPANVNSLNLRGNNLASKNCAELAKFLASIPASVTSLDLSANLLGL KSYAELAYIFSSIPNHVVSLNLCLNCLHGPSLENLKLLKDSLKHLQTVYLDYDIVKNMSKEQCKALGAAF PNIQKIILVDKNGKEIHPSHSIPISNLIRELSGKADVPSLLNQCLIFAQKHQTNIEDLNIPDELRESIQT CKPL |
| - |
| Nucleotide Sequence: 1065 bp [Download] |
| >gi|52840256|ref|NC_002942.5|:2711277-2712341 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome ATGAATTACAAGCTAACATTACACCCAGGCAGCAACCCAGTAGAGGAGTTTACCTCTATCCCACATGGGG TCACTTCACTTGATTTAAGTTTGAATAACTTATACAGTATAAGCACTGTTGAATTAATACAAGCCTTTGC TAATACACCCGCCAGCGTCACTTCACTGAATTTGAGTGGAAATTCCCTAGGCTTTAAAAACAGTGATGAA TTAGTTCAAATTCTCGCAGCCATCCCTGCCAACGTCACTTCATTGAATCTGAGTGGAAATTTCTTAAGTT ATAAAAGCAGTGATGAACTAGTAAAAACCCTGGCAGCCATCCCTTTCACCATCACCGTACTGGATTTAGG CTGGAATGATTTCAGCAGTAAAAGCAGCTCAGAATTTAAGCAAGCCTTTTCCAATTTACCTGCCAGCATC ACTTCACTGAATTTGAGAGGAAATGACTTAGGCATTAAAAGCAGCGATGAATTGATACAAATCTTGGCAG CTATCCCTGCCAACGTCAATTCCTTGAATTTGAGAGGTAATAACTTAGCCAGTAAAAACTGTGCTGAATT GGCAAAATTCTTGGCTTCCATTCCTGCTAGTGTGACTTCACTGGATTTAAGCGCGAATCTCTTAGGCCTG AAAAGCTATGCTGAATTAGCATATATCTTTTCTTCTATCCCAAATCACGTGGTTTCACTTAATTTGTGCC TTAATTGTTTGCATGGACCATCCCTTGAAAATTTGAAACTCCTTAAGGATTCACTCAAGCATCTACAGAC TGTTTATTTAGACTATGATATCGTCAAGAACATGTCCAAAGAACAATGCAAAGCACTAGGTGCCGCATTC CCCAATATACAAAAAATCATCCTGGTCGATAAGAATGGCAAAGAAATTCATCCGTCACATTCTATCCCGA TTTCTAATCTCATTAGAGAACTCTCTGGAAAAGCAGATGTACCATCCTTGTTAAATCAATGCCTTATTTT TGCCCAAAAACATCAAACAAACATTGAGGACTTGAATATTCCTGATGAGTTAAGGGAAAGCATTCAAACC TGCAAACCTCTCTGA |
| Reference |
(1) Weigele BA et al. (2017). A systematic exploration of the interactions between bacterial effector proteins and host cell membranes. Nat Commun. 8(1):532. [PudMed:28912547] 
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(2) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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(3) Burstein D; Zusman T; Degtyar E; Viner R; Segal G; Pupko T (2009). Genome-scale identification of Legionella pneumophila effectors using a machine learning approach. PLoS Pathog. 5(7):e1000508. [PudMed:19593377]
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| experimental literature |
| in silico analysis literature |