| Effector Protein ID: 52842461 |
 T4SS name [ID] | Dot/Icm [5] |
| Gene symbol | - |
| Locus tag | lpg2248 |
| Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
| Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2549049..2551283 [-] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | Lem21 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Unknown |
| UniProt ID | Q5ZTB4 |
| KEGG ID | lpn:lpg2248 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 744 a.a. [Download] |
| >gi|52842461|ref|YP_096260.1| hypothetical protein lpg2248 [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MAKTIKATGDGACLFNAVSIGLSVEILSGRLDSQLDTPGYQALLDEFAKHHPQFNPKSWKTLKEWLAYYN DTRDIELILAPVLFNLNQKYQDHLDEEILNELTNLVWKNKANIENGQAWFQLQNTGDLGEALFPKLENLD LKKDRAPLLDKLREILKDYKLELTRENVKQFLTEKAKELLSALKKKISSDPHAFQRGYSCDELKGMTDAL AISLVENREEDITDNRIKIRLENQEEHWNVLCNEEDSERFLDSTPSRLKMTSLEAYRGDKQVSAPTSEQL DLIEEPGVFLRERTIDNPGLGNCAFYAFAIGLVNIIQEEAKYNRRTMFDRWVGLDRSISGQYDEILKLNL EDPDKELLDRLQSSLRIVTYQYQIRELRNVCVFRNGNYNRLTGNSNFVNFAALYYGDPLDTDSRFNPFAD SVPILIKMANIDRDSVHPGHENDVLVPLFLDLLYGDTTNPADITLETEPKSDSPIITAMNNITQDFFWGT HLDLNYLAEAFEVNLHVLRNNSPIQEFVDIPERHTLTLTNSNNTHWTTQITTARATTGMLLGRNPHLSGA KRTGEQQRVNEGFPGKESANDFMIPPFDEISNPHHKKEVETNKPIGKGFFHDRPVVSEEQRKLEQLKRIV ANATLAYTTYSESIWFCFFHYHGQTGRDRANNFCKTFSKITDYGQAKEALVHYLNDSRNGNTHPHSYRTM LLHELQGNHDNKKDLQYLSRHFTSSLNKLASVLEVQLFANRYVP |
| - |
| Nucleotide Sequence: 2235 bp [Download] |
| >gi|52840256|ref|NC_002942.5|:c2551283-2549049 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome ATGGCGAAGACAATTAAGGCTACTGGAGATGGCGCTTGTCTGTTTAATGCAGTGTCAATCGGACTGAGTG TCGAGATCTTGAGCGGAAGACTGGATTCGCAGCTGGATACACCCGGTTATCAGGCCTTGCTGGATGAATT TGCCAAACATCACCCGCAATTTAACCCCAAAAGCTGGAAAACTTTAAAAGAGTGGCTAGCCTATTACAAC GATACCAGAGACATTGAGCTGATTTTAGCACCCGTATTATTTAATTTGAATCAGAAATATCAAGATCATC TGGATGAAGAAATTCTCAATGAATTAACCAATCTTGTATGGAAAAATAAGGCCAATATTGAAAATGGCCA AGCCTGGTTTCAATTGCAAAACACAGGGGATTTGGGCGAGGCACTTTTTCCCAAATTGGAAAATCTGGAT TTGAAAAAAGACAGGGCTCCTTTATTAGATAAATTACGAGAAATTCTTAAAGACTACAAACTTGAACTGA CACGTGAAAATGTAAAACAATTTCTGACCGAAAAGGCTAAAGAATTATTATCCGCTTTAAAGAAAAAGAT CAGTTCAGATCCTCATGCCTTTCAAAGGGGTTATAGCTGTGATGAGTTAAAGGGTATGACAGATGCCTTA GCGATCAGTCTGGTTGAGAATAGAGAAGAGGACATTACGGACAACCGAATCAAAATCAGATTAGAGAACC AGGAAGAGCATTGGAATGTATTGTGTAATGAAGAAGATAGCGAGCGTTTTCTGGATTCGACACCCTCACG TTTGAAAATGACTTCCTTGGAGGCTTATCGAGGTGATAAACAAGTTAGTGCACCAACATCTGAGCAGTTG GATTTGATTGAAGAGCCTGGCGTTTTTTTAAGAGAAAGAACCATTGATAACCCTGGCCTTGGCAATTGCG CTTTTTATGCCTTTGCGATAGGTTTGGTGAATATAATTCAGGAAGAGGCAAAGTATAATAGAAGAACCAT GTTTGATCGATGGGTAGGTCTCGACAGGTCAATTTCAGGTCAATACGATGAGATTTTGAAACTTAATCTC GAAGATCCCGATAAAGAATTACTGGACAGGTTGCAAAGCTCCTTAAGAATAGTGACTTATCAATATCAAA TACGAGAATTAAGAAATGTCTGTGTATTCAGAAATGGAAATTATAATCGATTAACTGGAAACAGTAATTT TGTTAATTTTGCAGCCTTATATTATGGCGATCCTCTGGATACAGATTCTCGATTCAATCCTTTTGCCGAT TCTGTTCCTATACTGATTAAAATGGCAAACATTGATCGAGACAGTGTTCATCCAGGACATGAAAACGATG TATTGGTTCCTCTCTTTTTAGATTTATTATATGGTGACACTACGAATCCAGCTGATATCACCCTGGAAAC AGAACCAAAGAGTGATTCACCTATCATTACTGCGATGAATAACATCACTCAGGATTTTTTCTGGGGCACC CATTTGGATTTAAATTATTTAGCCGAAGCGTTTGAGGTAAATCTTCATGTGCTAAGGAATAATAGTCCAA TTCAAGAGTTTGTCGATATTCCCGAGCGACACACTCTTACTTTAACTAATAGCAATAATACCCATTGGAC TACCCAAATTACAACGGCGAGAGCCACTACAGGAATGCTTTTGGGGCGAAACCCTCACCTGAGTGGAGCT AAAAGAACCGGGGAGCAACAGCGAGTTAACGAGGGGTTTCCTGGAAAAGAATCAGCCAACGATTTTATGA TACCTCCTTTTGATGAAATATCTAACCCCCATCATAAGAAAGAGGTAGAGACCAATAAACCAATCGGTAA AGGGTTTTTCCATGATAGACCGGTAGTTAGTGAAGAGCAGAGAAAATTGGAGCAATTAAAACGAATTGTT GCCAATGCTACGCTCGCTTACACTACCTACAGTGAAAGCATCTGGTTTTGCTTCTTTCATTATCATGGTC AAACAGGCCGAGATCGGGCTAATAACTTCTGCAAAACATTTTCTAAAATAACAGATTATGGCCAAGCCAA AGAAGCTTTGGTTCATTATTTAAATGACAGCAGGAATGGAAATACACATCCACATTCCTACAGAACAATG TTACTGCATGAATTACAAGGGAATCATGACAATAAAAAAGATTTGCAATATTTGTCCAGGCATTTTACTT CTTCTTTAAATAAACTAGCATCTGTTTTAGAAGTGCAATTGTTTGCCAACAGATATGTTCCTTAG |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
|
(2) Burstein D; Zusman T; Degtyar E; Viner R; Segal G; Pupko T (2009). Genome-scale identification of Legionella pneumophila effectors using a machine learning approach. PLoS Pathog. 5(7):e1000508. [PudMed:19593377] 
|
| experimental literature |
| in silico analysis literature |