| Effector Protein ID: 52842374 |
 T4SS name [ID] | Dot/Icm [5] |
| Gene symbol | - |
| Locus tag | lpg2160 |
| Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
| Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2423699..2425147 [-] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | lpg2160 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Unknown |
| UniProt ID | Q5ZTK1 |
| KEGG ID | lpn:lpg2160 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 482 a.a. [Download] |
| >gi|52842374|ref|YP_096173.1| hypothetical protein lpg2160 [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MFSANQSLDFAWLSMQMFLINLLKDKIMRYAVTYCAMDHEFSGNPFWHSCILLSQWDDNGKIEVVDNWGF YGVPSTVRDTWLSKLKIKLGLDVDLKGNHGMLRHEELRYLDVGYGLHGVTFELTKEKFDLLQLKCQTMLE EQKQAVKEVVESQGIAGKQKYRIYEHEEYSPLIFALEKIKAKQKGHQPRLKPFELNLSFTLWGPALNQSY TCKSLMVDLLKGILTQEQIARITEAGKHPTVPRYSGKLERIYLHSSGPLREHKKSSGAIVHYRDLQDEGV KLHWTLPPQEIEALSGDTIKLLEISEEYCDEVKQAISKLQKLEWLFIDAKLPEKYKPYQDDLVARIRQYY EAFAQVEPKKAKSTATGWMGFAFSLLSLPRDLDEKCLLQKLNNAKYLINSLYMAIVDHWKIYDDWPSETK EDSTEYNPLEALAAYLCEEDKKKLCKIIGRNYLDPSSEEEFDDIEESEWEQPELSRSVASPM |
| - |
| Nucleotide Sequence: 1449 bp [Download] |
| >gi|52840256|ref|NC_002942.5|:c2425147-2423699 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome CTGTTCTCAGCTAATCAATCTCTAGATTTTGCCTGGTTATCCATGCAGATGTTTTTAATCAATCTTCTTA AGGATAAAATAATGAGATATGCAGTTACCTATTGTGCGATGGATCATGAGTTTAGTGGTAATCCTTTTTG GCATAGTTGCATTTTATTATCTCAATGGGATGACAATGGAAAGATTGAGGTAGTCGATAATTGGGGTTTT TATGGGGTGCCATCTACTGTTCGTGATACGTGGTTAAGTAAACTGAAAATCAAGTTGGGTCTGGATGTTG ATTTGAAGGGCAATCATGGTATGTTACGACACGAAGAACTGCGTTATTTGGATGTTGGCTATGGTTTACA TGGAGTTACTTTTGAGTTAACCAAGGAAAAATTTGATTTACTGCAGTTGAAATGCCAAACAATGTTGGAA GAACAGAAGCAAGCAGTTAAGGAAGTTGTTGAATCACAGGGGATTGCTGGTAAACAAAAATACCGTATTT ATGAGCATGAAGAGTATTCCCCGTTAATTTTTGCTTTGGAAAAAATCAAGGCAAAACAAAAAGGCCATCA GCCAAGGCTTAAACCATTTGAGTTAAATTTGTCATTTACCCTGTGGGGGCCGGCTTTAAATCAATCCTAT ACTTGTAAATCACTGATGGTTGATTTATTAAAAGGCATACTGACTCAAGAGCAAATTGCCCGAATTACTG AAGCAGGAAAACACCCTACCGTACCAAGATACAGTGGTAAATTGGAAAGAATTTATTTGCATAGCAGCGG ACCATTACGTGAACATAAAAAATCTTCCGGTGCGATTGTTCATTATCGTGATTTGCAGGACGAGGGAGTC AAATTACATTGGACATTGCCTCCACAAGAAATTGAAGCGTTATCCGGAGATACCATCAAATTACTGGAAA TAAGCGAGGAGTATTGTGATGAGGTAAAACAAGCGATAAGCAAACTGCAAAAATTGGAGTGGTTATTTAT TGATGCCAAATTACCAGAGAAATATAAGCCTTATCAAGACGATTTGGTTGCTCGTATTCGGCAATATTAT GAAGCATTTGCTCAGGTTGAACCTAAAAAGGCTAAGTCAACAGCCACAGGCTGGATGGGATTCGCCTTTT CATTGCTCTCTTTGCCAAGAGATCTTGATGAAAAGTGTCTTTTGCAGAAATTAAATAATGCTAAATATCT GATTAACAGTCTATACATGGCTATTGTTGATCATTGGAAAATTTATGATGATTGGCCATCTGAAACTAAA GAAGACTCTACTGAATATAATCCTCTTGAAGCTTTGGCTGCTTATTTATGTGAAGAGGATAAGAAGAAAC TTTGTAAGATTATTGGACGAAATTATCTGGATCCTTCGTCAGAAGAGGAGTTTGATGATATTGAAGAGAG CGAATGGGAACAGCCAGAGTTGAGCAGGAGTGTTGCAAGTCCTATGTAA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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(2) Ensminger AW et al. (2010). E3 ubiquitin ligase activity and targeting of BAT3 by multiple Legionella pneumophila translocated substrates. Infect Immun. 78(9):3905-19. [PudMed:20547746] 
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| experimental literature |
| in silico analysis literature |