| Effector Protein ID: 52842370 |
 T4SS name [ID] | Dot/Icm [5] |
| Gene symbol | - |
| Locus tag | lpg2156 |
| Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
| Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2410554..2416334 [+] |
| Product | Sid related protein-like |
| Effector type | Protein |
| Descripton | SdeB |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Unknown |
| UniProt ID | Q5ZTK5 |
| KEGG ID | lpn:lpg2156 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | SidE [PF12252], Evalue: 0, Aligned region: 6..1467 SidE [PF12252], Evalue: 0, Aligned region: 1515..1862 |
| Protein Sequence: 1926 a.a. [Download] |
| >gi|52842370|ref|YP_096169.1| Sid related protein-like [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MGESKMPKYVEGVELTQEGMHAIFARMGHPEIKSGTIYNGVPTIDQEALDKQGFMPVLTGVGPKRDSGHW IMLIKGSGNQYHLFDPMGKISGEGYQDILATQLPKGSTLSVIPNEPGLNKGLCGYWVASVGLKACSALNK DNPPNLETLGQITTDAMKDELTDNGYLKITGWLKAVADKFPEGDPQPDAKALRQTTEKDLHIEIPSPVSP VKDTAPKEVSTKPTAPQVAPKYSLDSKLLENDDDVLDTIKYVHKEYLGKPYPGPLKNPKAPEEGRLPPNE GPDRGPHGLAHTVRTMACAEVMIEEARKAQLRGETLGKAKNGQTLADVTPEELKKILIAQAFFVVGRDDE RSGYDDVHKRNFYAEYHEKSEQAFRKYVEDNKLIGKIFKDQKEVDFYAAIILDKNHEWDATPAHILINQG HMVDLMRTKAPAEVALERTYNTLKGTVGSKGAEVVLKAHRDFFFATGAVVPLVNPEAIDDPSRGGPYENP YSGEKFVIVDDKVPASKKDLPKAVNRDYKLKDNERFLTIKEYYAFPDVQQTYPGYKTRLEASSYYFPTPF AGECEQNPAKCLGAIQKARSKLQTDAIKNGFQSSSEKERRQPNMDEIAAARIIQQIMANPDCIHDDHVLI NGQKLEEKFFRDLLAKCDMAVVGSLLNDTDIKNIDTLMRHEKNTEFHSTDPKAVPVKIGDAWENRIRTKG GDVTQMKHDLIFLMQNDAWYFSRVNAIAQNRDKGSNFKEVLFTTLMTPLTNKSLIDTSHVPAPKKLYRGL NLPQEFTNKLINQSNAIIANTENTLFTDLSAEAFKQIKLNDFSQMSGKTCASTTKNMKLLTDIWGSNVIF EMLDPDGLLHPKQVGTHMTGSEDEFSVYLPEDVALVPTKVTLEGKTDTGEDRYIFTLVAVKSPDFIPRHE SGYAVEPFMKMQKEKVTQALDAIEKDKDSYNIDEQLKSLRTEMVRQAKLPLREGVFDRLSHRFSLETSDN KISPERRDFLNQHVIPVLQECHIALRTNNMEMMQKALAKFPTDKQWSAFKSGEAVRAKAQMDVLKQQIEK KIMLQTQIIPALTECGEALDKQNVTEALQALNKLPAEKEIGKAKGIGQELRGQIVGVKQELTGNLESLQR AVTTPVVKDAEKMRVRYETLLTDVTKRVTDFEKIKPANLDGYNKAIADLNNIQQELNLLRNEKIRMHTDK DKAVDFSDIEALEKRLKEAQPNLYPSLVEGTTKGIQELEKIPKSISFDDVKSMTSKINGYLETLEFIRNE RVKKHGESTEPLDMSDLDKLKNQLQGVSQHLAQILLNGAKNSLDKIKDPVTLEKEGQYIKRCLDHFAELE KTLDSSVKGMKQKEDFNTYKNSLMEKQEKAYPEMLQLQYKSEALITQLRNLCNIHHDNLAKTREEQQQLL NKTGGILGGFFSQITTAISQAESKKANEFARFKTELNNDKSDVSQLIQFLVKKKPSELEENLGISKENAE QLHGLLKQLDAKATPIDKLQENTRLIDEISTKMGSKPVSPEHVAATKAREYYQFLLYGATQKIGNFEKIK PIDPESYKKAMSDLNNMQEALQFLRSEKSRIHDGKEKAVEFSDIEALEKRVQNAQPKLLTALLDKTTREI SALVKIPRKLTFEDIKSMTTKLNSYLETLELIRNERIKQHGKSPELLDMSDLDSLKGQLQTFNQNLTGMI LNATKDGLDRINDRANFKEGEPYVKACLDLLTELEKTLDSSVKGMKQKEDISACRNSLLDKQEKANSGML DLQSKSKDLVTQLRDICKIHHGNLAEARRTRLHSLDNQEGGLLGGLWSVTNKLGVTTDTVGIERMQIKMK EQALARFKTELNNDKYDTNQVIAFLANKKPSELEEGLGISKENAEELHGLLSKLTSKMTSKIEIEENTQL IDEISTKIGTEPVKLESTHTVDEDERDTYHRESGYF |
| - |
| Nucleotide Sequence: 5781 bp [Download] |
| >gi|52840256|ref|NC_002942.5|:2410554-2416334 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome TTGGGAGAAAGTAAAATGCCTAAATATGTAGAAGGGGTAGAGTTAACTCAAGAAGGCATGCATGCTATTT TTGCACGGATGGGGCATCCCGAGATTAAAAGCGGTACTATTTATAACGGAGTACCTACTATTGATCAAGA AGCTCTCGACAAGCAAGGTTTTATGCCTGTATTAACAGGGGTAGGACCTAAGAGAGACTCCGGTCACTGG ATCATGTTAATCAAAGGATCAGGCAACCAATACCATCTCTTTGATCCAATGGGTAAAATTTCAGGTGAAG GCTATCAAGACATTTTAGCCACTCAATTGCCCAAAGGCTCCACCCTTTCTGTTATCCCCAATGAGCCCGG CCTAAACAAGGGGCTATGTGGCTATTGGGTTGCTTCTGTTGGATTAAAGGCATGTTCTGCACTCAATAAG GATAATCCTCCCAATTTAGAAACTTTGGGTCAAATCACAACGGATGCAATGAAGGATGAATTAACCGATA ATGGTTATCTGAAAATTACCGGCTGGCTAAAAGCTGTTGCTGATAAATTTCCAGAAGGTGACCCCCAACC CGATGCGAAAGCATTAAGACAAACCACTGAAAAAGATTTGCACATAGAGATACCCTCTCCTGTTTCTCCA GTCAAAGACACAGCTCCTAAGGAAGTTTCTACAAAACCTACTGCACCACAAGTAGCTCCCAAGTATTCTT TAGACAGTAAGTTATTAGAGAATGACGATGATGTTCTAGACACCATAAAGTATGTTCATAAAGAGTATTT AGGAAAACCATATCCTGGCCCATTAAAAAATCCAAAAGCACCGGAAGAAGGACGACTTCCTCCAAATGAA GGGCCCGATCGAGGACCTCATGGTCTTGCTCATACGGTAAGAACAATGGCTTGTGCCGAGGTGATGATAG AAGAAGCACGTAAAGCTCAACTGAGAGGAGAAACATTAGGTAAAGCAAAAAATGGTCAGACTTTAGCTGA TGTAACACCAGAAGAACTGAAAAAAATTCTCATCGCACAAGCCTTTTTTGTGGTAGGAAGGGATGATGAG CGTTCCGGCTATGATGACGTCCACAAGAGAAATTTTTACGCGGAATATCATGAGAAAAGTGAGCAAGCGT TCAGGAAATACGTTGAAGATAACAAGCTCATCGGCAAAATATTTAAAGATCAAAAAGAAGTCGATTTCTA TGCTGCGATTATTCTGGATAAAAATCATGAATGGGATGCCACCCCGGCACATATCCTGATAAATCAAGGC CATATGGTCGATTTAATGAGGACTAAAGCACCTGCCGAAGTCGCATTGGAACGTACCTACAATACACTGA AAGGTACCGTCGGTTCAAAAGGTGCTGAAGTGGTCCTCAAGGCCCATCGAGATTTTTTCTTTGCCACAGG CGCTGTTGTTCCCTTAGTTAACCCTGAAGCAATTGATGACCCCAGTAGAGGTGGACCTTATGAAAATCCT TATAGCGGGGAGAAATTTGTTATTGTTGATGATAAGGTACCAGCTTCCAAGAAAGACTTACCAAAAGCTG TCAATCGTGACTATAAACTGAAAGATAACGAACGATTCCTAACCATAAAGGAATACTACGCTTTTCCTGA TGTGCAGCAAACCTACCCTGGTTACAAAACACGTTTGGAAGCAAGCTCTTACTATTTCCCAACACCATTT GCAGGAGAATGTGAACAAAACCCTGCAAAATGTCTGGGAGCTATCCAAAAAGCCCGTTCAAAACTACAAA CGGATGCCATTAAAAATGGCTTTCAATCAAGCTCTGAGAAAGAGAGAAGACAACCTAATATGGATGAAAT TGCGGCCGCCCGCATTATTCAACAAATCATGGCCAATCCTGATTGCATCCATGACGATCATGTGCTCATC AATGGTCAAAAACTGGAAGAAAAATTCTTCCGTGACTTGTTAGCGAAATGTGATATGGCTGTTGTAGGCT CACTGCTCAATGACACCGACATCAAAAATATCGATACTTTAATGCGACACGAGAAAAACACTGAGTTTCA TTCTACTGACCCCAAAGCAGTTCCAGTGAAAATTGGAGACGCCTGGGAAAATAGAATAAGAACCAAAGGT GGCGACGTCACTCAAATGAAGCATGATTTAATTTTCCTCATGCAAAATGACGCCTGGTACTTTAGCCGAG TCAATGCCATCGCACAAAACCGGGATAAAGGCTCCAATTTCAAAGAAGTGCTGTTTACCACCTTAATGAC GCCTTTGACTAATAAATCATTAATAGATACATCCCACGTCCCAGCTCCGAAAAAACTGTATCGTGGATTA AATCTGCCACAAGAATTTACCAATAAATTAATCAATCAATCCAATGCCATTATTGCCAATACAGAAAATA CGCTTTTTACTGATCTCTCTGCTGAAGCCTTCAAACAAATCAAGTTAAATGATTTTAGCCAAATGTCTGG CAAAACCTGTGCCAGCACAACCAAAAATATGAAACTTTTAACCGATATATGGGGCTCCAATGTCATTTTT GAAATGCTTGACCCGGATGGTTTACTGCATCCAAAACAAGTAGGAACCCATATGACTGGATCAGAAGATG AATTTTCCGTTTATTTGCCGGAAGATGTCGCTTTAGTTCCAACCAAGGTAACTCTTGAAGGAAAAACAGA CACAGGAGAAGATCGGTATATCTTTACACTGGTTGCTGTTAAAAGCCCTGACTTTATACCACGACATGAA AGCGGCTATGCGGTTGAACCCTTCATGAAAATGCAAAAAGAGAAAGTCACCCAGGCATTGGATGCCATTG AAAAGGATAAAGACAGCTATAACATCGACGAACAACTAAAAAGCTTAAGAACAGAAATGGTCAGGCAAGC CAAATTGCCTCTTAGAGAAGGGGTTTTTGATAGACTCTCTCATCGTTTTTCTCTGGAAACCAGTGATAAC AAAATATCTCCGGAACGCAGAGATTTTCTTAACCAACACGTCATCCCTGTATTACAGGAATGTCATATTG CTCTTAGAACAAACAATATGGAGATGATGCAAAAAGCCTTGGCAAAATTCCCTACTGATAAACAATGGTC TGCTTTTAAATCAGGAGAAGCAGTCAGAGCCAAAGCTCAAATGGATGTATTAAAGCAACAGATCGAAAAG AAAATCATGCTGCAAACTCAAATTATCCCAGCTCTCACGGAATGTGGTGAAGCACTGGATAAACAAAATG TCACAGAAGCATTACAAGCGCTTAATAAACTGCCTGCAGAAAAGGAAATAGGTAAAGCCAAGGGGATAGG ACAAGAGTTAAGAGGGCAAATTGTAGGTGTTAAGCAAGAGCTGACTGGAAATCTTGAATCCTTGCAACGC GCAGTCACTACCCCTGTTGTAAAAGATGCTGAGAAAATGAGAGTACGGTATGAAACGCTTCTCACAGACG TGACCAAACGAGTCACCGACTTTGAAAAAATCAAACCGGCCAATCTTGACGGTTATAATAAGGCCATTGC CGATTTAAATAACATACAACAAGAATTAAACCTTTTGCGCAATGAAAAAATTCGCATGCATACTGACAAA GATAAAGCAGTGGACTTTTCTGACATAGAGGCCTTGGAAAAGAGATTAAAAGAAGCACAGCCCAATTTAT ATCCCTCGCTTGTGGAAGGAACAACAAAAGGTATTCAAGAACTTGAAAAAATACCCAAGTCAATCAGTTT TGACGATGTTAAATCAATGACATCCAAGATTAATGGCTACCTGGAAACCTTGGAATTCATTCGTAATGAA AGAGTTAAAAAGCATGGTGAATCCACTGAGCCACTGGATATGTCTGATCTGGATAAATTAAAAAATCAAC TACAAGGCGTGAGTCAGCATTTAGCCCAAATTTTATTAAATGGAGCTAAAAACTCACTCGATAAAATCAA GGATCCGGTTACACTCGAAAAAGAAGGACAATATATAAAACGCTGCCTTGACCATTTTGCTGAACTTGAA AAAACTCTGGATAGTTCGGTAAAAGGAATGAAACAAAAAGAAGACTTTAACACCTATAAAAACTCTCTAA TGGAGAAGCAGGAAAAAGCCTATCCAGAAATGTTGCAATTGCAATACAAGAGTGAAGCATTGATTACACA ATTACGTAATCTATGCAATATTCATCATGATAATTTGGCCAAAACGAGAGAGGAACAACAACAGCTACTG AACAAGACCGGAGGAATATTAGGCGGTTTCTTTAGCCAGATAACGACTGCTATAAGTCAAGCCGAGTCAA AGAAAGCAAATGAATTTGCAAGATTTAAAACTGAATTAAATAATGACAAAAGTGATGTGAGTCAACTTAT TCAATTTCTGGTAAAGAAAAAACCATCCGAATTGGAAGAAAATTTGGGCATATCGAAAGAAAATGCTGAG CAATTACATGGACTGTTAAAGCAACTAGACGCAAAAGCTACTCCAATAGATAAATTGCAGGAAAACACAA GATTAATTGATGAAATATCAACCAAAATGGGTAGTAAACCCGTCTCGCCAGAACATGTTGCCGCAACAAA AGCGAGAGAATACTATCAATTTCTTCTATATGGAGCGACACAAAAAATCGGTAACTTTGAAAAGATCAAA CCTATCGATCCCGAAAGCTATAAAAAGGCTATGTCAGACTTAAATAACATGCAAGAAGCATTACAATTCC TACGTAGTGAAAAATCCCGAATACATGATGGCAAAGAAAAAGCAGTGGAATTCTCTGACATAGAAGCCTT GGAAAAACGAGTACAAAATGCTCAACCTAAATTACTGACAGCACTCCTGGATAAAACAACCAGAGAAATC TCAGCATTAGTAAAAATACCCAGGAAATTGACCTTTGAAGATATAAAATCAATGACAACCAAGCTTAACA GTTACCTGGAAACCCTGGAGTTGATTCGTAATGAAAGAATCAAACAACACGGTAAATCCCCTGAACTTCT GGATATGTCCGATTTGGATAGTTTAAAAGGTCAATTGCAAACCTTTAATCAAAATTTGACTGGCATGATA CTAAATGCTACTAAAGATGGTCTAGATAGAATCAATGACAGGGCTAACTTTAAGGAAGGAGAACCTTACG TAAAAGCATGTCTTGATCTTTTAACAGAACTTGAAAAAACACTGGATAGTTCGGTAAAAGGAATGAAACA AAAAGAAGACATTAGCGCCTGTAGAAATTCTCTCCTTGATAAACAGGAAAAAGCCAATTCCGGAATGCTG GATTTGCAATCCAAGAGTAAAGATCTGGTTACCCAATTACGTGATATCTGTAAAATTCATCACGGTAATT TAGCTGAAGCAAGAAGGACCAGGCTTCACTCACTTGATAATCAGGAAGGCGGATTATTAGGGGGATTATG GTCTGTTACTAACAAATTAGGTGTTACCACAGACACAGTAGGTATCGAGAGGATGCAAATAAAAATGAAG GAGCAAGCACTGGCAAGATTTAAAACAGAATTGAATAATGACAAATACGATACGAATCAAGTCATTGCCT TTTTAGCAAATAAAAAACCATCAGAGCTGGAAGAAGGTTTAGGCATATCGAAAGAAAATGCCGAAGAATT ACATGGACTGTTAAGTAAACTCACTAGTAAAATGACTTCGAAAATCGAAATTGAAGAAAATACACAGTTA ATTGATGAAATTTCAACTAAAATAGGTACCGAACCCGTAAAACTCGAGTCGACTCACACAGTAGATGAAG ATGAGCGTGATACCTATCACCGAGAAAGTGGTTACTTTTAA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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(2) Burstein D; Zusman T; Degtyar E; Viner R; Segal G; Pupko T (2009). Genome-scale identification of Legionella pneumophila effectors using a machine learning approach. PLoS Pathog. 5(7):e1000508. [PudMed:19593377] 
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| experimental literature |
| in silico analysis literature |