| Effector Protein ID: 52842369 |
 T4SS name [ID] | Dot/Icm [5] |
| Gene symbol | - |
| Locus tag | lpg2155 |
| Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
| Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2407667..2410288 [+] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | SidJ |
| T4CP requirement | T4CP Depedent |
| Target/Effection | SidJ is required for efficient recruitment of endoplasmic reticulum proteins to the bacterial phagosome. (Liu and Luo, 2007) |
| UniProt ID | Q5ZTK6 |
| KEGG ID | lpn:lpg2155 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 873 a.a. [Download] |
| >gi|52842369|ref|YP_096168.1| hypothetical protein lpg2155 [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MFGFIKKVLDFFGVDQSEDNPSETAVETTDVSTKIKTTDTTQEESSVKTKTVVPTQPGGSVKPETIAPDQ QKKHQIKTETTTSTTKQKGPKVTLMDGHVKQYYFARRGETSTHDTSLPPPVKVLSGRSIPLKEIPFEATR NELVQIYLTSIDKLIKSNKLNSIPSQQIASHYLFLRSLANSETDGIKKNQILSLAKPLGTYLASKEPHVW KMINELIEKSEYPIIHYLKNNRAHSNFMLALIHEYHKEPLTKNQSAFVQKFRDSSVFLFPNPIYTAWLAH SYDEDSSFNPMFRERLSTNFYHSTLTDNLLLRTEPKEVTLSSEHHYKKEKGPIDSSFRYQMSSDRLLRIQ GRTLLFSTPQNDVVAVKVQKKGEPKSTLEEEFEMADYLLKHQRRLDVHSKLPQPLGQYSVKKSEILEISR GSLDFERFKTLIDDSKDLEVYVYKAPQSYFTYLHDKNQDLEDLTASVKTNVHDLFVLLREGIVFPQLADI FHTHFGEDEREDKGRYQALVQLLNVLQFQLGRIDKWQKAVEYVNLRSSGLADLGDSLPITSLFTSSDFTK HYFSELLTGGYHPTFFDKSSGTANSLFTGKRRLFGNYLYLNTIAEYLLVIQLTLGSYGDKVTRDMMDKPK KEAVWRELANVMFTSCAEAIHIMTGIPQSRALTLLKQRANIEKHFRQTQFWMTPDYSKLDEDTLQMEQYS IYSGEPEYEFTDKLVSGVGLSVDGVHQDLGGYNRESPLRELEKLLYATVTLIEGTMQLDKEFFKQLEQVE KILSGEIKTDANSCFEAVAQLLDLARPGCHFQKRLVLSYYEEAKLKYPSAPTDAYDSRFQVVARTNAAIT IQRFWREARKNLSEKSDIDSEKPESERTTDKRL |
| - |
| Nucleotide Sequence: 2622 bp [Download] |
| >gi|52840256|ref|NC_002942.5|:2407667-2410288 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome ATGTTTGGTTTCATAAAGAAAGTACTTGATTTTTTTGGTGTTGATCAATCTGAAGATAATCCATCTGAGA CTGCGGTGGAAACAACCGATGTTTCAACAAAAATCAAAACCACTGACACCACCCAGGAAGAGAGTTCAGT CAAAACCAAAACGGTTGTTCCTACCCAACCTGGGGGTTCTGTCAAACCCGAGACAATCGCACCTGACCAA CAAAAAAAACACCAAATAAAAACAGAAACGACTACAAGCACAACCAAACAAAAAGGCCCCAAAGTAACAC TAATGGATGGTCACGTGAAACAATATTATTTTGCCCGGCGAGGTGAAACAAGCACTCATGACACCTCTCT GCCACCACCTGTGAAGGTGTTAAGTGGGCGCTCTATCCCATTAAAAGAAATTCCTTTTGAAGCTACCAGA AATGAATTAGTCCAGATTTATCTCACTTCTATTGATAAACTCATCAAAAGCAACAAATTAAACTCTATTC CATCACAACAAATCGCCTCTCACTATCTCTTTCTTAGATCACTTGCCAACTCAGAGACTGATGGAATTAA AAAAAATCAAATACTGTCATTAGCCAAGCCATTGGGCACTTACCTTGCCTCTAAAGAGCCCCATGTATGG AAAATGATCAATGAACTCATTGAAAAAAGTGAATACCCAATTATTCATTATTTAAAAAATAACCGTGCTC ATTCCAATTTCATGCTGGCATTAATTCATGAGTATCATAAGGAACCATTAACCAAAAACCAAAGCGCCTT TGTACAAAAATTTAGGGACTCCTCTGTCTTTCTCTTCCCTAACCCAATTTATACAGCATGGCTCGCTCAT TCCTATGATGAGGACTCCAGCTTTAATCCTATGTTTCGTGAAAGATTATCCACCAACTTTTATCATTCCA CTCTGACCGATAATCTCTTGTTAAGAACAGAACCTAAGGAAGTAACTCTTTCATCAGAGCATCATTATAA AAAGGAAAAAGGACCAATTGACTCGTCTTTTCGTTATCAAATGTCAAGTGATCGGTTATTGCGTATCCAG GGCAGAACTTTACTGTTTAGTACCCCCCAAAATGATGTGGTTGCAGTCAAAGTACAAAAAAAAGGAGAGC CTAAGTCCACCTTGGAAGAAGAATTCGAAATGGCAGATTATTTGCTGAAACATCAACGTCGTTTGGATGT ACACAGCAAATTGCCACAACCGCTTGGACAATACTCTGTTAAAAAATCAGAGATTTTGGAAATAAGCAGG GGATCATTAGATTTTGAGCGTTTTAAAACCTTAATAGACGACTCTAAAGACCTTGAAGTGTATGTTTATA AAGCCCCCCAGTCTTATTTCACTTACCTACACGATAAAAATCAGGATTTGGAAGATCTGACAGCTTCTGT TAAAACAAATGTGCACGATCTCTTTGTTCTATTACGCGAAGGAATCGTATTTCCCCAATTAGCCGATATC TTCCATACTCATTTTGGTGAAGACGAGCGCGAAGACAAAGGAAGATACCAGGCATTAGTTCAACTTTTGA ATGTTTTACAGTTCCAATTAGGGCGCATTGATAAATGGCAAAAAGCTGTGGAATACGTCAATTTGCGCAG CAGTGGTCTGGCTGATTTGGGAGACAGTCTGCCCATAACTAGCCTGTTCACTTCATCTGATTTCACAAAA CATTATTTCTCTGAACTGCTTACAGGAGGATATCACCCAACCTTCTTTGACAAGTCATCTGGTACAGCCA ACTCTTTATTCACCGGCAAGCGCCGATTATTTGGTAATTACTTGTATCTCAATACCATAGCAGAATATTT GCTGGTTATTCAGTTAACACTCGGCAGCTATGGGGATAAAGTGACTCGAGACATGATGGATAAACCTAAA AAAGAGGCGGTATGGCGAGAATTGGCAAACGTCATGTTTACAAGTTGTGCAGAAGCCATTCATATCATGA CTGGAATACCTCAATCGCGAGCACTGACACTACTAAAACAACGAGCTAATATTGAAAAACATTTCAGACA GACACAATTCTGGATGACGCCTGATTATTCCAAACTGGATGAAGATACACTGCAAATGGAGCAATACAGC ATTTATTCCGGTGAGCCAGAATATGAATTCACTGATAAATTAGTCTCTGGTGTTGGATTGTCCGTCGATG GTGTTCATCAGGACTTGGGTGGATATAACAGGGAAAGCCCATTAAGAGAACTTGAAAAACTGCTCTATGC CACAGTAACACTGATTGAAGGAACCATGCAACTTGATAAAGAGTTTTTTAAACAATTGGAACAAGTTGAA AAAATACTTTCTGGTGAGATAAAAACTGATGCCAATTCGTGCTTTGAAGCAGTTGCCCAACTTCTGGACC TTGCAAGGCCTGGGTGCCATTTTCAGAAAAGATTGGTTTTGTCCTACTACGAAGAAGCCAAGCTTAAATA TCCCTCCGCACCAACTGACGCCTATGATTCACGTTTTCAAGTAGTCGCCAGAACCAATGCCGCAATAACC ATTCAACGATTCTGGCGAGAAGCACGCAAAAACTTGTCAGAAAAATCGGATATCGATTCTGAAAAGCCGG AATCCGAACGTACTACTGATAAACGTTTGTGA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| (2) Luo ZQ (2012). Legionella secreted effectors and innate immune responses. Cell Microbiol. 14(1):19-27. [PudMed:21985602] |
(3) Burstein D; Zusman T; Degtyar E; Viner R; Segal G; Pupko T (2009). Genome-scale identification of Legionella pneumophila effectors using a machine learning approach. PLoS Pathog. 5(7):e1000508. [PudMed:19593377] 
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(4) Kubori T; Hyakutake A; Nagai H (2008). Legionella translocates an E3 ubiquitin ligase that has multiple U-boxes with distinct functions. Mol Microbiol. 67(6):1307-19. [PudMed:18284575]
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| experimental literature |
| in silico analysis literature |