| Effector Protein ID: 52842367 |
 T4SS name [ID] | Dot/Icm [5] |
| Gene symbol | - |
| Locus tag | lpg2153 |
| Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
| Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2401678..2406279 [+] |
| Product | Sid related protein-like |
| Effector type | Protein |
| Descripton | SdeC |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Unknown |
| UniProt ID | Q5ZTK8 |
| KEGG ID | lpn:lpg2153 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | SidE [PF12252], Evalue: 0, Aligned region: 1..1472 |
| Protein Sequence: 1533 a.a. [Download] |
| >gi|52842367|ref|YP_096166.1| Sid related protein-like [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MPKYVEGVELTQEGMHAIFARMGHGDITSGSIYNGVPTIDTEALNRQGFMPVLTGVGPRRDSGHWIMLIK GPGNQYFLFDPLGKTSGEGYKNTLLAQLPIASTLSVIPNEPGLNKGLCGYWVASVGLKARSELSKDNPPN LETLGQITTDAMKDELTDNGYLKITGWLKAVADKFPEGDPQPDAKALRQTTEKDLHIEIPSPVSPIKDTA PKEVSTKPTAPQVAPKHSLDSKLLENDDDVLDTIKYVHKEYLGKPYPGPLKNPKAPEEGRLPPNEGPDRG PHGLAHTVRTMACAEVMIEEARKAQLRGETLGKAKNGQTLADVTPEELKKILIAQAFFVVGRDDERSGYD DVHKRNFYAEYHEKSEQAFRKYVEDNKLIGKIFKDQKEVDFYAAIILDKNHEWDATPAHILINQGHMVDL MRTKAPAEVALERTYNTLKGTVGSKGAEVVLKAHRDFFFATGAVVPLVNPEAIDDPSRGGPYENPYSGEK FVIVDDKVPASKKDLPKAVNRDYKLKDNERFLTIKEYYAFPDVQQTYPGYKTRLEASSYYFPTPFAGECE QNPAKCLGAIQKARSKLQTDAIKNGFQSSSEKERRQPNMDEIAAARIIQQIMANPDCIHDDHVLINGQKL EEKFFRDLLAKCDMAVVGSLLNDTDIKNIDTLMRHEKNTEFHSTDPKAVPVKIGDAWENRIRTKGGDVTQ MKHDLIFLMQNDAWYFSRVNAIAQNRDKGSNFKEVLFTTLMTPLTNKSLIDTSHVPAPKKLYRGLNLPQE FTNKLINQSNAIIANTENTLFTDLSAEAFKQIKLNDFSQMSGKTCASTTKNMKLLTDIWGSNVIFEMLDP DGLLHPKQVGTHMAGSEDEFSVYLPEDVALVPTKVTLEGKTDTGEDRYIFTLVAVKSPDFIPRHESGYAV EPFMKMQKEKVTQALDAIEKDKDSYNIDEQLKSLRTEMVRQAKLPLREGVFDRLSHRLSLETSDNKISPE RRDFLNQHVIPVLQECHIALRANDMDMMQKALAKFPTDKQWSAFKSGEAVRAKAQMDVLKQQIEKKIMLQ TQIIPALTECGEALDKQNVTEALQALNKLPAEKEIGKVKTIGQELRGQIVGVKQELTGNLEPLQRATTTP IVQDAEKIKVRYETLLTDVTKRVTDFEKIKPANLDGYNKAIADLNNIQQELNLLRNEKIRMHTDKDKAVD FSDIEALDKRLQDVQSKLPTQLLEQTSKDVAKLAKMPEKITFNDIKSMTSKMNNYLETLELIRNDRIKKH AGSTDPLDMSDLDGLKGQLQTYNQSMADILLRAAKSSLDKIKDPATFEKESPYIKQCFDHLAELEKTLDD SDKGRKQKEDFTAYKSALMDKQEKAYPEMLQLQYKSEALIMQLRDICKIHHDNLAEARRVRLQQLDSQGG GLLGGLWAVTNTIGLTTDNVNIEKMQIRMKEQTLRAFKTELTNDKLNTDQVIAFLAKGSPSELQEALGIS KENAEQLHGLLKQLEIKTASTDKLQEIEKLIDEVSTKIGKEPVKQDHTITIDEEESDDIRYGF |
| - |
| Nucleotide Sequence: 4602 bp [Download] |
| >gi|52840256|ref|NC_002942.5|:2401678-2406279 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome ATGCCTAAATACGTAGAAGGGGTAGAATTAACTCAAGAAGGTATGCATGCTATTTTTGCTCGTATGGGGC ATGGCGATATCACCAGCGGTAGCATTTATAATGGAGTACCGACTATTGACACAGAGGCCCTGAACAGACA AGGCTTCATGCCTGTTTTAACAGGAGTAGGCCCCAGAAGAGATTCTGGTCACTGGATCATGTTAATCAAA GGGCCTGGTAACCAATATTTTCTCTTTGACCCACTGGGTAAAACATCAGGCGAAGGCTATAAAAATACTT TATTAGCCCAATTACCCATAGCCTCTACTCTTTCTGTTATCCCCAATGAGCCCGGCCTAAACAAGGGGCT ATGTGGCTATTGGGTAGCCTCTGTTGGATTAAAGGCACGTTCTGAACTCAGTAAGGATAATCCTCCCAAT TTAGAAACTTTGGGTCAAATCACAACGGATGCAATGAAGGATGAATTAACCGATAATGGTTATCTGAAAA TTACCGGCTGGCTAAAAGCTGTTGCTGATAAATTTCCAGAAGGTGACCCCCAACCCGATGCGAAAGCATT AAGACAAACCACTGAAAAAGATTTGCACATAGAGATACCCTCTCCTGTTTCTCCAATCAAAGACACAGCT CCTAAGGAAGTTTCTACAAAACCTACTGCACCACAAGTAGCTCCCAAGCATTCTTTAGACAGTAAGTTAT TAGAGAATGACGATGATGTTCTAGACACCATAAAGTATGTTCATAAAGAGTATTTAGGAAAACCATATCC TGGCCCATTAAAAAATCCAAAAGCACCGGAAGAAGGACGACTTCCTCCAAATGAAGGGCCCGATCGAGGA CCTCATGGTCTTGCTCATACGGTAAGAACAATGGCTTGTGCCGAGGTGATGATAGAAGAAGCACGTAAAG CTCAACTGAGAGGAGAAACATTAGGTAAAGCAAAAAATGGTCAGACTTTAGCTGATGTAACACCAGAAGA ACTGAAAAAAATTCTCATCGCACAAGCCTTTTTTGTGGTAGGAAGGGATGATGAGCGTTCCGGCTATGAT GACGTCCACAAGAGAAATTTTTACGCGGAATATCATGAGAAAAGTGAGCAAGCGTTCAGGAAATACGTTG AAGATAACAAGCTCATCGGCAAAATATTTAAAGATCAAAAAGAAGTCGATTTCTATGCTGCGATTATTCT GGATAAAAATCATGAATGGGATGCCACCCCGGCACATATCCTGATAAATCAAGGCCATATGGTCGATTTA ATGAGGACTAAAGCACCTGCCGAAGTCGCATTGGAACGTACCTACAATACACTGAAAGGTACCGTCGGTT CAAAAGGTGCTGAAGTGGTCCTCAAGGCCCATCGAGATTTTTTCTTTGCCACAGGCGCTGTTGTTCCCTT AGTTAACCCTGAAGCAATTGATGACCCCAGTAGAGGTGGACCTTATGAAAATCCTTATAGCGGGGAGAAA TTTGTTATTGTTGATGATAAGGTACCAGCTTCCAAGAAAGACTTACCAAAAGCTGTCAATCGTGACTATA AACTGAAAGATAACGAACGATTCCTAACCATAAAGGAATACTACGCTTTTCCTGATGTGCAGCAAACCTA CCCTGGTTACAAAACACGTTTGGAAGCAAGCTCTTACTATTTCCCAACACCATTTGCAGGAGAATGTGAA CAAAACCCTGCAAAATGTCTGGGAGCTATCCAAAAAGCCCGTTCAAAACTACAAACGGATGCCATTAAAA ATGGCTTTCAATCAAGCTCTGAGAAAGAGAGAAGACAACCTAATATGGATGAAATTGCGGCCGCCCGCAT TATTCAACAAATCATGGCCAATCCTGATTGCATCCATGACGATCATGTGCTCATCAATGGTCAAAAACTG GAAGAAAAATTCTTCCGTGACTTGTTAGCGAAATGTGATATGGCTGTTGTAGGCTCACTGCTCAATGACA CCGACATCAAAAATATCGATACTTTAATGCGACACGAGAAAAACACCGAGTTTCATTCTACCGACCCCAA AGCAGTTCCAGTGAAAATTGGAGACGCCTGGGAGAATAGAATAAGAACGAAAGGTGGCGACGTCACTCAA ATGAAGCATGATTTAATTTTCCTCATGCAAAATGACGCCTGGTACTTTAGCCGAGTCAATGCCATCGCAC AAAACCGGGATAAAGGCTCCAATTTCAAAGAAGTGCTGTTTACCACCTTAATGACGCCTTTGACTAATAA ATCATTAATAGATACATCCCACGTCCCAGCTCCGAAAAAACTGTATCGTGGATTAAATCTGCCACAAGAA TTTACCAATAAATTAATCAATCAATCCAATGCCATTATTGCCAATACAGAAAATACGCTTTTTACTGATC TCTCTGCTGAAGCCTTCAAACAAATCAAGTTAAATGATTTTAGCCAAATGTCTGGCAAAACCTGTGCCAG CACAACCAAAAATATGAAACTTTTAACCGATATATGGGGCTCCAATGTCATTTTTGAAATGCTTGACCCG GATGGTTTGCTGCACCCAAAACAAGTAGGAACCCATATGGCTGGTTCCGAAGATGAATTTTCCGTTTATT TGCCGGAAGATGTCGCTTTAGTTCCAACCAAGGTAACTCTTGAAGGAAAAACAGACACAGGAGAAGATCG GTATATCTTTACACTGGTTGCTGTTAAAAGCCCTGACTTTATACCACGACATGAAAGCGGCTATGCGGTT GAGCCCTTCATGAAAATGCAAAAAGAGAAAGTCACCCAGGCATTGGATGCCATTGAAAAGGATAAAGACA GCTATAACATCGACGAACAACTAAAAAGCTTAAGAACAGAAATGGTTAGGCAAGCCAAATTGCCTCTTAG AGAAGGGGTTTTTGATAGACTCTCTCATCGCCTTTCTCTGGAAACCAGTGATAACAAAATATCTCCGGAA CGCAGAGATTTTCTTAACCAACACGTCATCCCTGTATTACAGGAATGCCATATCGCGCTTAGAGCAAACG ATATGGACATGATGCAAAAAGCCTTGGCAAAATTCCCTACTGATAAACAATGGTCTGCTTTTAAATCAGG AGAAGCGGTTAGGGCCAAAGCTCAAATGGATGTATTAAAGCAACAGATCGAAAAGAAAATCATGCTGCAA ACTCAAATTATCCCGGCTCTCACGGAATGTGGTGAAGCACTGGATAAACAAAATGTCACAGAGGCATTGC AAGCGCTCAATAAACTGCCTGCAGAAAAAGAAATAGGCAAGGTCAAGACAATAGGACAAGAGTTAAGAGG ACAAATTGTAGGTGTTAAGCAAGAGCTGACCGGAAATCTTGAGCCCCTGCAACGCGCTACCACTACTCCA ATTGTACAAGATGCTGAAAAAATAAAAGTACGGTATGAAACGCTTCTCACAGACGTGACCAAACGAGTCA CCGACTTTGAAAAAATCAAACCAGCCAATCTTGACGGTTATAATAAGGCCATTGCCGATTTAAATAACAT ACAACAAGAATTAAACCTTTTGCGCAATGAAAAAATTCGCATGCATACTGACAAAGACAAAGCAGTGGAC TTTTCTGACATAGAAGCGTTGGATAAGAGATTACAAGACGTTCAATCCAAATTGCCAACTCAACTTTTAG AGCAAACGTCTAAAGATGTTGCAAAATTAGCAAAAATGCCGGAAAAGATTACCTTTAATGACATCAAATC AATGACATCCAAAATGAATAATTATCTGGAAACCTTGGAATTGATTCGTAATGACAGGATCAAGAAGCAT GCTGGATCTACCGACCCTCTTGATATGTCGGATTTGGATGGATTAAAAGGTCAACTGCAAACTTATAATC AAAGCATGGCTGATATCCTATTGCGCGCTGCCAAAAGTTCTCTAGACAAAATTAAAGATCCAGCTACTTT TGAAAAAGAATCCCCATACATCAAACAATGTTTTGATCATTTAGCAGAACTTGAAAAAACTCTGGATGAT TCAGACAAGGGAAGAAAACAAAAAGAAGACTTTACTGCCTATAAAAGCGCTTTAATGGATAAACAGGAAA AGGCTTATCCAGAAATGCTACAGTTACAATACAAGAGTGAAGCATTGATTATGCAATTACGTGATATCTG TAAAATTCACCATGACAATTTAGCTGAAGCAAGAAGAGTGAGACTTCAACAACTCGATAGTCAGGGAGGC GGACTTTTAGGTGGATTATGGGCTGTAACCAATACCATAGGTCTTACTACAGACAATGTGAATATTGAAA AAATGCAGATTAGAATGAAGGAGCAAACTCTTAGAGCGTTTAAGACAGAACTTACTAATGACAAGCTTAA TACGGATCAAGTCATTGCCTTTTTAGCAAAAGGAAGTCCATCTGAATTGCAAGAAGCTTTAGGAATATCA AAAGAGAATGCAGAACAATTGCATGGATTGTTAAAACAACTGGAGATTAAAACAGCATCAACCGATAAAC TCCAGGAAATTGAAAAGCTAATTGATGAAGTCTCAACTAAAATAGGGAAAGAACCAGTAAAACAAGATCA TACCATCACAATAGATGAGGAAGAAAGCGATGACATAAGGTATGGTTTCTAA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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(2) Burstein D; Zusman T; Degtyar E; Viner R; Segal G; Pupko T (2009). Genome-scale identification of Legionella pneumophila effectors using a machine learning approach. PLoS Pathog. 5(7):e1000508. [PudMed:19593377] 
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| experimental literature |
| in silico analysis literature |