Effector Protein ID: 52842362 |
T4SS name [ID] | Dot/Icm [5] |
Gene symbol | - |
Locus tag | lpg2148 |
Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
Location [Strand] | 2395991..2397271 [+] |
Product | hypothetical protein |
Effector type | Protein |
Descripton | MvcA |
T4CP requirement | T4CP Depedent |
Target/Effection | Unknown |
UniProt ID | Q5ZTL3 |
KEGG ID | lpn:lpg2148 |
PDB ID | NA |
Domain hit(s) vs Pfam | NA |
Protein Sequence: 426 a.a. [Download] |
>gi|52842362|ref|YP_096161.1| hypothetical protein lpg2148 [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MIVRGINMTKIKLESPGFMVHKKLKSMSQSYGVMMTGVPAEVLGQMQAERSIPSINKTGNLKQQIAKEVS KVCHMMTEPTQSCGQASNDVCELLLGKIEAEKFHFTKYEALSADGDNLKNVLENTAPSSTNLLIRFEIDR EDPPIVLVKTKNENFNPETAVKNKIYLLENKLYFIDKMGNLFNLGPGKKKCTQLFNAIGDSAEYSLCDPF VLEEPEKPEDFAISEIVDIFNEQKERFDFWIGSHSFTIYIPQTLGESPRQFYPYQAYFGSHTLQDWFVSD KDEYLSRIGIDKYIEKLAVLGKTTNTKERSDIYAEFFSKRGREAFFCAHLNEKRQPLRVKFKITEINPEL ALKNLQETQEFIDTHPGENPSDKVENYRNRAKLAMTEHLESLLDIKPESSPSLFWKNVDKKEQEMTDSSR YKKGPS |
- |
Nucleotide Sequence: 1281 bp [Download] |
>gi|52840256|ref|NC_002942.5|:2395991-2397271 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome TTGATTGTGCGTGGCATTAATATGACAAAAATAAAACTGGAATCGCCGGGTTTCATGGTACACAAAAAGT TGAAAAGCATGTCCCAAAGCTATGGAGTCATGATGACTGGTGTCCCTGCTGAGGTGTTAGGACAAATGCA GGCAGAGCGATCTATCCCCAGCATTAATAAAACAGGGAACCTTAAGCAACAAATTGCAAAGGAGGTTTCA AAGGTATGTCATATGATGACTGAACCCACTCAGAGTTGTGGCCAAGCCAGTAATGATGTGTGTGAATTGC TTTTAGGAAAAATTGAAGCGGAAAAATTCCATTTCACCAAATATGAAGCATTATCAGCAGATGGAGACAA TCTAAAAAATGTTTTAGAAAATACAGCCCCATCCAGCACTAACCTATTAATACGATTTGAAATTGACAGA GAAGACCCTCCCATTGTATTGGTCAAAACAAAAAACGAGAATTTCAATCCGGAAACCGCTGTGAAGAATA AAATTTACCTATTAGAAAATAAATTATATTTTATTGACAAGATGGGTAATCTTTTTAACCTTGGACCAGG TAAAAAAAAATGTACGCAGTTATTCAACGCAATTGGAGACTCAGCAGAATATAGTCTTTGTGATCCTTTT GTTCTTGAAGAGCCTGAAAAACCTGAGGATTTTGCAATAAGTGAGATCGTAGATATCTTTAACGAACAAA AAGAGAGATTCGATTTTTGGATCGGGTCGCATTCTTTTACAATATATATCCCTCAAACGCTGGGTGAATC ACCACGCCAATTCTATCCTTATCAAGCTTACTTTGGTTCACACACTTTACAGGATTGGTTTGTCAGCGAT AAAGATGAATACCTGTCGCGAATTGGCATCGACAAGTATATTGAAAAATTAGCTGTACTGGGAAAAACAA CAAACACGAAAGAACGCTCGGATATTTATGCAGAATTTTTTTCAAAGCGAGGCCGGGAAGCATTTTTTTG CGCCCACCTTAATGAAAAAAGACAACCATTACGAGTAAAGTTCAAAATAACTGAAATTAACCCTGAATTG GCATTAAAGAATTTACAGGAAACGCAAGAATTTATTGATACCCATCCAGGAGAAAATCCATCAGATAAAG TAGAAAATTATAGAAATAGAGCAAAATTGGCAATGACCGAACACCTGGAGAGCCTATTAGACATCAAGCC TGAATCAAGCCCCTCTTTATTTTGGAAAAATGTCGATAAGAAAGAACAAGAAATGACTGACAGTAGCAGG TATAAAAAGGGGCCAAGCTAA |
Reference |
(1) Valleau D et al. (2018). Discovery of Ubiquitin Deamidases in the Pathogenic Arsenal of Legionella pneumophila. Cell Rep. 23(2):568-583. [PudMed:29642013] |
(2) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] |
experimental literature |
in silico analysis literature |