| Effector Protein ID: 52842195 |
 T4SS name [ID] | Dot/Icm [5] |
| Gene symbol | - |
| Locus tag | lpg1978 |
| Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
| Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2217148..2219082 [-] |
| Product | teichoic acid biosynthesis protein |
| Effector type | Protein |
| Descripton | SetA |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Vesicle trafficking |
| UniProt ID | Q5ZU30 |
| KEGG ID | lpn:lpg1978 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | TcdA_TcdB [PF12919], Evalue: 7e-12, Aligned region: 29..84 TcdA_TcdB [PF12919], Evalue: 7e-12, Aligned region: 112..138 Gly_transf_sug [PF04488], Evalue: 2.8e-10, Aligned region: 42..147 Caps_synth [PF05704], Evalue: 1.2e-08, Aligned region: 100..189 |
| Protein Sequence: 644 a.a. [Download] |
| >gi|52842195|ref|YP_095994.1| teichoic acid biosynthesis protein [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MYKIYSYLGWRIDMKTENLPQAGQEAQIDKKIHFIWVGHIMPQKNIQVVSEWAEKNPGYETIIWVDKKIA PAKELDLFILDMKSKGITVKDINEEGVCRDSIRHELDQESPNYGMVSDMLRLNILAAEGGIYLDSDILCS APFPDEIYAPFGFLLSPWSQGANNTLCNDIILCSKGNQIIQQLADAIEQSYIARDSFEFTHEYASMKETK GERIAKTLGVTGPGFLFHQLKKMGILNDKSEMEAIHWELQDQRYLIDGSVKEPDYFYVPQNNTNDASWVP SIKRPGIENMSFQERLENAVQLIAFDIQKTGLFNLDHYANELKVKQNSWCIAAETSPELKPDSYLLIRPR DKTGEWTLYYVDEDKKLNPVTLPVIKGAIKLSEVSDPLRKFHTLLSQVSDPVNPTAHELKQIGRALIELK PRQDEWHCKNKWSGAEEIAQELWQRITSNETLRAQIKQCFTQFESLKPRVAELGLTRASGAGTEVEAHES TVKEQEIISQNTVGEEGTKEKNSVQLASENSSDEKIKTAHDLIDEIIQDVIQLDGKLGLLGGNTRQLEDG RVINIPNGAAMIFDDYKKYKQGELTAESALESMIKIAKLSNQLNRHTFFNQRQPETGQFYKKVAAIDLQT TIAAEYDNNHGLRI |
| - |
| Nucleotide Sequence: 1935 bp [Download] |
| >gi|52840256|ref|NC_002942.5|:c2219082-2217148 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome CTGTATAAAATATATTCATATCTAGGTTGGAGAATTGATATGAAGACAGAAAATTTACCACAGGCTGGTC AAGAGGCTCAAATTGACAAAAAAATCCATTTTATATGGGTTGGTCATATTATGCCTCAAAAAAACATCCA GGTTGTCTCCGAATGGGCTGAAAAGAACCCTGGCTATGAAACGATTATCTGGGTAGATAAAAAAATAGCG CCTGCCAAAGAACTCGATCTTTTTATTCTAGACATGAAATCCAAAGGCATCACGGTAAAAGATATTAATG AAGAAGGTGTGTGCCGGGATAGCATACGTCATGAACTCGATCAGGAATCTCCTAATTATGGGATGGTGAG TGATATGTTGCGATTAAATATCTTGGCTGCAGAGGGAGGAATTTATTTGGATTCAGATATCTTATGCTCT GCTCCTTTCCCTGATGAAATTTATGCGCCTTTTGGGTTTCTATTGTCTCCCTGGTCTCAGGGAGCTAATA ATACTCTTTGCAATGATATCATTTTATGTAGCAAAGGAAATCAAATAATCCAGCAATTAGCAGATGCGAT CGAGCAATCCTATATTGCGAGAGATTCTTTTGAGTTCACTCATGAATATGCATCAATGAAGGAAACAAAA GGGGAGAGAATTGCTAAAACATTAGGTGTGACTGGTCCAGGGTTTTTATTTCATCAGTTAAAAAAAATGG GAATCCTGAATGACAAAAGTGAAATGGAAGCGATTCATTGGGAATTACAAGATCAAAGGTATTTAATCGA TGGTAGTGTGAAGGAGCCAGACTATTTTTATGTACCACAGAACAATACAAATGACGCCAGTTGGGTTCCC AGTATCAAAAGGCCGGGGATAGAAAACATGAGTTTTCAAGAAAGACTTGAAAATGCAGTTCAATTGATAG CTTTTGATATTCAAAAGACTGGTTTATTTAATTTGGATCATTATGCCAATGAATTAAAAGTAAAACAAAA CAGCTGGTGTATTGCTGCAGAAACATCCCCTGAGCTAAAACCGGATTCCTATTTGTTGATTAGACCCAGG GACAAAACTGGGGAATGGACTCTATATTATGTTGATGAGGATAAAAAATTAAATCCTGTGACATTACCAG TCATTAAAGGGGCTATTAAACTTTCAGAAGTCTCAGATCCCCTCAGAAAATTTCATACCTTATTAAGCCA GGTTTCTGATCCTGTAAATCCAACAGCTCATGAATTAAAGCAGATTGGCAGAGCCTTAATAGAACTTAAA CCCAGGCAAGATGAATGGCACTGCAAAAACAAATGGTCTGGTGCTGAGGAAATCGCACAGGAGCTTTGGC AAAGAATTACTTCAAATGAAACGTTAAGAGCACAAATTAAACAATGTTTCACTCAATTTGAATCATTAAA ACCAAGGGTAGCTGAGTTAGGTTTAACAAGAGCCTCTGGAGCGGGAACAGAAGTTGAAGCGCATGAGTCT ACTGTTAAAGAACAAGAAATTATCTCGCAGAACACTGTTGGAGAAGAAGGTACTAAAGAAAAGAATTCTG TCCAATTAGCGTCAGAAAACTCATCTGACGAGAAGATAAAAACTGCTCATGATTTAATTGATGAAATTAT TCAGGATGTGATTCAGCTGGATGGAAAATTAGGTTTATTGGGTGGAAATACTCGCCAGCTGGAAGATGGT AGAGTTATTAATATACCTAATGGCGCTGCTATGATATTTGATGATTATAAAAAATATAAGCAAGGAGAGT TAACGGCAGAAAGTGCGTTAGAATCTATGATAAAAATCGCAAAACTGTCTAATCAACTTAATCGGCATAC CTTTTTTAATCAAAGGCAACCAGAAACCGGGCAATTCTATAAAAAAGTGGCTGCAATTGATTTACAAACA ACCATTGCAGCGGAATACGATAACAATCATGGTTTAAGAATATAA |
| Reference |
(1) Jank T et al. (2012). Domain organization of Legionella effector SetA. Cell Microbiol. 14(6):852-68. [PudMed:22288428] 
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(2) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| experimental literature |
| in silico analysis literature |