| Effector Protein ID: 52842178 |
 T4SS name [ID] | Dot/Icm [5] |
| Gene symbol | - |
| Locus tag | lpg1961 |
| Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
| Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2194507..2196039 [-] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | lpg1961 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Glycosyltransferase |
| UniProt ID | Q5ZU47 |
| KEGG ID | lpn:lpg1961 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | TcdA_TcdB [PF12919], Evalue: 2.3e-05, Aligned region: 96-162 Gly_transf_sug [PF04488], Evalue: 2.1e-05, Aligned region: 62-167 |
| Protein Sequence: 510 a.a. [Download] |
| >gi|52842178|ref|YP_095977.1| hypothetical protein lpg1961 [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MLCESFMSDSEYESDSESDSDSKSEYELRTLPSKIHFVWVGGPIRAQYLRTIMDVAAVALKSGFEVNLWV DNEMNYIKTSTQEGIDIPNLRIRNVHELEEGMRNAPFYEEGDRYKKFWEYVNRERVGFKNLAAAADFFRF EILRQEGGYYFDTDIVFYLDENSQFVADEVAFGIKAHVDLHTGSFTDPRGGSTTHYVNTLGDVNNDIIAA IPDHEVMEDAILNAMQRHEEYDSSPLPLESLKKKFGPYGNLMDAKRTPYQLKEPMDFRKYQTIAAGPGAL QEALRDYMEGVEVEDSSLLVTLKVGNQYSNVANDKDKKPIMGIEVVSKCDKTWLTKKRKAAQKAFDTDSI VIEPSLSKESGHPVSNREAYSDDDEEYSDELTEETGFHGNLRKEQFINELKDYIIIKKEEARQALEVKEN EEGHDSEEKILSKHFKTRHIEITKGFSVEQKIAAVEKLISLLQEKDGAELLNAIDYAALTSSRLGKLVER YDDLILKEYVVPDEYGEKPY |
| - |
| Nucleotide Sequence: 1533 bp [Download] |
| >gi|52840256|ref|NC_002942.5|:c2196039-2194507 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome TTGTTATGCGAGAGTTTCATGAGCGATTCTGAATATGAAAGTGATTCTGAATCTGATAGCGATTCTAAAT CTGAATATGAGCTCCGTACGCTACCATCCAAAATACATTTTGTTTGGGTTGGGGGACCTATTCGAGCTCA ATATTTACGCACTATTATGGATGTTGCTGCAGTAGCACTAAAAAGTGGTTTTGAGGTTAATTTATGGGTT GATAATGAAATGAATTACATTAAAACATCAACTCAAGAAGGAATAGACATACCTAACTTAAGAATAAGGA ATGTTCATGAATTGGAAGAAGGGATGCGAAATGCCCCCTTTTACGAGGAGGGAGACAGGTACAAAAAATT TTGGGAATATGTCAATAGAGAACGAGTCGGTTTTAAAAATCTTGCGGCAGCCGCAGATTTTTTTCGCTTC GAAATTTTAAGGCAAGAGGGCGGTTATTACTTCGATACCGATATCGTTTTTTATTTGGATGAAAACTCAC AATTTGTAGCAGATGAGGTTGCTTTTGGCATAAAAGCGCATGTGGATTTGCATACAGGATCATTCACGGA TCCACGTGGAGGTTCTACTACCCATTATGTCAATACTTTAGGAGATGTTAATAACGATATTATTGCTGCT ATTCCTGATCATGAGGTTATGGAAGATGCAATTCTAAATGCTATGCAACGTCATGAAGAGTATGATTCAT CCCCATTGCCCCTGGAATCGCTTAAAAAAAAATTCGGTCCATATGGCAATCTGATGGATGCTAAACGCAC TCCTTATCAATTGAAGGAACCTATGGATTTTAGAAAATATCAAACTATTGCAGCTGGTCCTGGTGCATTA CAGGAGGCATTGCGTGATTACATGGAAGGTGTTGAAGTAGAAGATTCCAGCTTGCTAGTTACCTTAAAAG TTGGTAATCAATACTCGAATGTAGCAAATGATAAGGATAAAAAACCGATTATGGGAATCGAAGTGGTCAG TAAGTGTGATAAAACTTGGCTGACTAAAAAAAGAAAAGCTGCGCAAAAAGCTTTTGATACTGATTCGATT GTTATAGAGCCCTCACTTTCAAAGGAATCTGGGCACCCAGTAAGTAATAGAGAGGCATACTCTGATGATG ACGAAGAGTATAGTGATGAATTAACAGAAGAAACCGGATTCCATGGCAATTTGCGCAAGGAACAATTTAT CAATGAATTGAAAGATTATATTATCATAAAAAAAGAAGAAGCAAGGCAGGCTTTGGAAGTGAAAGAGAAT GAAGAAGGCCATGATTCTGAGGAAAAAATTCTAAGTAAGCATTTTAAAACACGTCACATAGAGATAACAA AAGGGTTCTCTGTTGAACAGAAAATTGCTGCCGTAGAGAAGCTTATTAGTTTACTGCAGGAAAAGGATGG GGCGGAACTGCTTAATGCGATTGATTATGCAGCGCTTACCAGTTCTCGCCTGGGTAAGTTAGTCGAAAGA TACGATGATTTGATACTTAAAGAATATGTTGTGCCTGATGAGTATGGGGAAAAACCATACTGA |
| Reference |
(1) Nimrod Nachmias et al. (2019). Study of Legionella Effector Domains Revealed Novel and Prevalent Phosphatidylinositol 3-Phosphate Binding Domains. Infect Immun. 87(6). pii: e00153-19. [PudMed:30962397] 
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| experimental literature |