| Effector Protein ID: 52842175 |
 T4SS name [ID] | Dot/Icm [5] |
| Gene symbol | legL5 |
| Locus tag | lpg1958 |
| Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
| Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 2189637..2191265 [+] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | LegL5 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Unknown |
| UniProt ID | Q5ZU50 |
| KEGG ID | lpn:lpg1958 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 542 a.a. [Download] |
| >gi|52842175|ref|YP_095974.1| hypothetical protein lpg1958 [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MFQIGEHNMILIYKLTLTKLTEDELKKDFATIPSWATHLDLSNNRLGETSNEELIRVFAKIPGWISHIKL RFNNLGQKNGKDLAKAFAKIPISVTTLDLGSNQLGKKSGEELANAFAGIPTSVTRLILSQNELYKRTGGE LATAFAKIPSSVTHLVLVNNGLGEKNGKELATAFANIPSSVTTLDLALNDLSKIKSTELAVIFTKIPTSV TQLDLSHNNLNKKSGKNLAKIFANIPTSVTNLNLSCNELGKKSGKGLAAAFAKIPTSVTDLNIEDNDLDN RTGKELAMAFAHIPAFVNTLRLGDNNLGNKSGEELAEIFAKIPLSVTSLDLRYNELGKRNGKELAIAFAK IPSSVTNLNLKFNHLGKITGEELAMAFANIPTNVDSLVLANNELGAKSGEELAKIFSKIPASITSLNMGN DWFAVIEKLSQQKMVLSTITHVVIDYSSAQEHSAKLKLLATVFPNLNKVTFMDIHGNNALAGQNPIEEAK WLKLCGIKNSVPSLLSQALFFVAKNKEHRSIQDYPSLLPKELTDSISSLLKC |
| - |
| Nucleotide Sequence: 1629 bp [Download] |
| >gi|52840256|ref|NC_002942.5|:2189637-2191265 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome CTGTTTCAAATAGGAGAGCACAATATGATACTAATTTATAAGCTTACTCTGACAAAACTTACAGAGGATG AATTAAAAAAAGATTTTGCCACAATTCCAAGCTGGGCAACTCACCTTGACTTATCAAACAATCGCCTCGG CGAAACAAGCAATGAAGAATTAATAAGAGTCTTTGCCAAAATTCCAGGCTGGATAAGCCATATTAAATTA AGATTTAACAACCTCGGCCAAAAAAACGGTAAGGACTTGGCAAAAGCTTTTGCCAAAATACCAATTTCGG TGACTACGCTTGATTTAGGTTCCAATCAACTTGGCAAAAAAAGTGGAGAGGAATTGGCAAATGCATTCGC AGGAATTCCAACATCGGTGACCAGGCTTATATTGAGCCAAAACGAACTTTACAAGAGAACTGGGGGGGAA CTGGCAACTGCATTTGCCAAAATCCCGAGCTCAGTAACCCATCTTGTTTTAGTTAATAATGGATTGGGTG AAAAAAATGGCAAGGAATTGGCAACTGCTTTCGCTAACATTCCAAGCTCAGTGACCACCCTTGATTTAGC TCTTAATGATCTTTCCAAAATAAAAAGCACGGAATTGGCAGTAATCTTTACAAAAATTCCAACTTCTGTA ACTCAACTTGATCTGAGCCACAATAACCTCAATAAAAAAAGTGGGAAGAACTTAGCAAAAATTTTTGCCA ACATTCCTACCTCCGTAACTAACCTTAATTTAAGTTGCAATGAATTGGGCAAAAAAAGTGGCAAGGGGTT AGCAGCTGCCTTTGCCAAAATTCCAACCTCAGTGACAGACCTTAATATAGAAGATAATGACCTCGATAAC AGAACTGGCAAGGAATTGGCAATGGCTTTTGCACACATTCCAGCTTTCGTGAATACTCTTCGATTAGGAG ATAATAACCTCGGCAATAAAAGTGGAGAAGAATTAGCAGAGATCTTTGCCAAAATCCCACTATCGGTGAC TTCACTTGATTTACGCTACAATGAACTTGGAAAAAGAAATGGTAAGGAGTTAGCAATTGCTTTCGCCAAG ATTCCCAGCTCAGTGACTAATCTTAATTTAAAATTTAATCACCTTGGTAAAATAACTGGAGAAGAGCTGG CTATGGCCTTTGCCAACATCCCAACCAATGTCGATTCACTCGTTTTAGCGAATAACGAGCTTGGGGCTAA AAGTGGAGAGGAATTAGCCAAGATTTTTAGTAAAATTCCAGCTTCTATAACCAGCTTGAACATGGGCAAC GATTGGTTTGCTGTCATAGAAAAATTAAGTCAGCAAAAAATGGTTCTATCTACAATAACCCATGTGGTTA TAGATTACAGCTCAGCTCAAGAGCACTCAGCAAAACTCAAATTGCTTGCAACTGTTTTTCCTAATCTAAA TAAAGTCACTTTTATGGATATTCATGGAAATAACGCCCTAGCTGGTCAAAATCCTATAGAGGAAGCTAAA TGGCTGAAATTATGTGGCATTAAAAATTCCGTGCCCTCCCTACTCAGCCAAGCCTTGTTTTTTGTTGCAA AAAATAAAGAACATAGGTCCATTCAAGATTACCCAAGCCTGCTTCCTAAAGAGCTTACTGACTCAATTTC ATCGCTATTGAAATGCTAA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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(2) Burstein D; Zusman T; Degtyar E; Viner R; Segal G; Pupko T (2009). Genome-scale identification of Legionella pneumophila effectors using a machine learning approach. PLoS Pathog. 5(7):e1000508. [PudMed:19593377] 
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(3) Zusman T; Degtyar E; Segal G (2008). Identification of a hypervariable region containing new Legionella pneumophila Icm/Dot translocated substrates by using the conserved icmQ regulatory signature. Infect Immun. 76(10):4581-91. [PudMed:18694969]
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(4) Kubori T; Hyakutake A; Nagai H (2008). Legionella translocates an E3 ubiquitin ligase that has multiple U-boxes with distinct functions. Mol Microbiol. 67(6):1307-19. [PudMed:18284575]
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| experimental literature |
| in silico analysis literature |