| Effector Protein ID: 52841929 |
 T4SS name [ID] | Dot/Icm [5] |
| Gene symbol | legC3 |
| Locus tag | lpg1701 |
| Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
| Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 1895076..1896758 [+] |
| Product | kinectin 1 |
| Effector type | Protein |
| Descripton | PpeA/legC3 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Vesicle trafficking |
| UniProt ID | Q5ZUU1 |
| KEGG ID | lpn:lpg1701 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 560 a.a. [Download] |
| >gi|52841929|ref|YP_095728.1| kinectin 1 [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MIMFLANCNIEELVTEHIKQFLADEELSFSGLKDLILSKAPIPWIHSSVTATLLKSRDSDKTEVKKNLEQ QSYKAQLAEDKIQKEQDDAEALKDKKLKEVLTRELNHIPTQISEQQTELRLLHYKLERLFESQAKVDVIQ HPDSPMKKIKPSSSHSASIERLQRSINEREIKIQSLFEQEVNNKIKLNEIEKRASVRSQHHTKRVKRAQA RIGYNSTGEDILSTLSGKNQSILLRSIQKQHHALEKKCSDLIQEADQINYPLFLEELQKYLNKKKHTLSS QEVDALKSVIKYIKQHLEFEHEVINTQSSLHIKKQSISSQIVKLRELQNKLKTLKNNNPNLTAANEELVS RNLELTAMKEHHADLRHRLGTPALLLFGLTFLFSIPLILTISGVIPFFIAPALLYILVSAPPTILLLSTL GVGIAAIVFSFKMHSNESAIKSNLQTIETNSNQMSRNSQNLKSLETLTIPTLDMQIKKDENLRDQLMLSL QKQQRQAAQAFQKAKEVECLSYATSSLLNSGNTQSSDPSLSTHSEESDEGLNDSNDSLQALEEETVNEIA |
| - |
| Nucleotide Sequence: 1683 bp [Download] |
| >gi|52840256|ref|NC_002942.5|:1895076-1896758 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome GTGATTATGTTTTTGGCCAACTGCAATATCGAGGAATTAGTTACAGAACATATAAAACAATTTCTAGCGG ATGAAGAGTTGTCTTTCTCTGGCTTAAAAGATTTAATTCTGAGTAAAGCCCCAATTCCCTGGATTCACTC CTCTGTAACAGCCACTCTGCTTAAATCCAGAGACTCCGATAAAACAGAAGTAAAAAAAAACCTTGAACAA CAATCTTATAAAGCTCAACTGGCTGAAGACAAGATTCAAAAAGAGCAGGATGATGCTGAAGCATTAAAAG ATAAAAAATTAAAGGAAGTTTTAACTCGTGAATTAAACCACATCCCAACTCAAATCAGTGAACAGCAAAC GGAACTCAGATTACTTCATTATAAACTAGAGCGACTCTTTGAAAGCCAAGCTAAAGTCGATGTGATTCAA CATCCTGATTCTCCTATGAAAAAGATAAAGCCGTCCTCCAGTCACTCTGCGTCGATTGAGCGCCTGCAAA GATCTATTAATGAGCGTGAGATTAAAATTCAATCACTTTTTGAACAGGAAGTTAACAACAAGATAAAATT AAACGAAATTGAAAAGCGTGCCAGTGTACGCTCACAACATCACACTAAAAGGGTTAAACGCGCTCAGGCA AGAATTGGATACAATAGTACTGGAGAGGATATTCTCAGTACATTATCAGGGAAAAATCAATCCATTTTGT TGCGCAGTATTCAAAAACAACATCATGCTCTTGAAAAAAAATGCAGTGATCTCATTCAGGAAGCTGATCA GATTAATTACCCATTATTTCTTGAGGAACTTCAAAAGTATTTAAATAAAAAAAAGCATACTTTATCTTCT CAAGAGGTCGATGCATTAAAGTCTGTTATAAAATATATAAAGCAACACTTGGAATTTGAGCATGAGGTAA TCAATACACAATCCAGTCTCCATATTAAAAAGCAATCCATCAGTTCCCAGATTGTAAAATTACGAGAATT ACAAAATAAACTAAAAACCTTAAAAAACAATAACCCCAATTTGACAGCGGCAAATGAAGAATTAGTTTCA CGTAATTTGGAATTAACGGCCATGAAAGAGCATCATGCTGACCTACGTCATCGCTTGGGCACACCCGCAT TACTTTTATTTGGATTAACTTTTCTATTTTCAATTCCTCTTATTTTAACCATAAGCGGAGTAATTCCTTT TTTCATTGCGCCTGCGTTGCTTTATATTTTGGTCTCAGCGCCTCCAACCATCTTGCTGCTATCAACTCTT GGTGTTGGCATAGCAGCTATCGTTTTCAGCTTCAAAATGCATTCCAATGAATCAGCTATTAAATCCAATT TGCAAACGATTGAAACAAACTCTAATCAAATGAGCCGAAATTCCCAAAATTTAAAATCATTGGAAACGCT TACCATCCCCACTCTGGATATGCAAATCAAAAAAGATGAAAATTTAAGAGATCAATTAATGCTTTCTTTA CAAAAACAGCAACGTCAAGCTGCCCAGGCATTCCAGAAAGCAAAAGAGGTAGAGTGCCTATCCTATGCTA CCTCTTCACTTTTAAATTCCGGCAATACCCAATCCAGTGATCCATCATTATCCACGCATTCAGAAGAGAG CGACGAAGGGCTAAATGACTCGAATGACTCTCTGCAAGCGCTGGAAGAAGAAACAGTTAATGAGATAGCG TAA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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(2) Burstein D; Zusman T; Degtyar E; Viner R; Segal G; Pupko T (2009). Genome-scale identification of Legionella pneumophila effectors using a machine learning approach. PLoS Pathog. 5(7):e1000508. [PudMed:19593377] 
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(3) de Felipe KS et al. (2008). Legionella eukaryotic-like type IV substrates interfere with organelle trafficking. PLoS Pathog. 4(8):e1000117. [PudMed:18670632]
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| experimental literature |
| in silico analysis literature |