| Effector Protein ID: 52841870 |
 T4SS name [ID] | Dot/Icm [5] |
| Gene symbol | sidB |
| Locus tag | lpg1642 |
| Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
| Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 1815442..1816695 [-] |
| Product | protein SidB |
| Effector type | Protein |
| Descripton | SidB |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Unknown |
| UniProt ID | Q5ZV00 |
| KEGG ID | lpn:lpg1642 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | DUF818 [PF05677], Evalue: 1.2e-06, Aligned region: 15..198 Abhydrolase_1 [PF00561], Evalue: 3.9e-06, Aligned region: 141..205 Abhydrolase_5 [PF12695], Evalue: 5.4e-06, Aligned region: 139..232 Abhydrolase_6 [PF12697], Evalue: 8.4e-06, Aligned region: 123..205 Lipase_3 [PF01764], Evalue: 5.7e-05, Aligned region: 168..207 |
| Protein Sequence: 417 a.a. [Download] |
| >gi|52841870|ref|YP_095669.1| protein SidB [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MAKIYNAPKPKYSGWEWFKFIAIRTVFPPVLLWDLIKIGANKLLGEWVSGLVLPAQNENFDDLAISDDTV SNYNEDDLICEKHDVITHDGAHLDTFEVRHRSQESIDPKYQKYIINLVGNGMCYEHIIDDIKEDSKALKA NVIGFNLRGVGQSTGKAKSSEDLVADGIAQVQRLLDQGVSPQNITLKGHSLGAGVASLVAQHFHQLGQPI NLFNSRSFSTITNFLVGHMRLERDEIGRAIGHKDSTVGTILGWLAKPFIKFGVALAKWEINAGSAFKSVP EAYKDYIVVRSRKEIRGERIDDAVIPHYASIHKELASERHKKKAEIDEEIANLDDIIRKADPLAKPGLAN ARDALVQAREKIKSDRKMETDVQYANGHNSDWNALHNRSGKSAQTFFREFVQRTEADHAVKSIPEIN |
| - |
| Nucleotide Sequence: 1254 bp [Download] |
| >gi|52840256|ref|NC_002942.5|:c1816695-1815442 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome ATGGCTAAAATTTATAATGCACCAAAACCTAAATATAGTGGTTGGGAATGGTTTAAATTTATTGCAATTC GAACGGTTTTTCCCCCTGTTTTATTATGGGATTTAATAAAAATTGGGGCCAATAAACTGCTTGGTGAATG GGTTAGTGGTTTAGTGCTGCCAGCACAAAATGAAAATTTTGATGATTTAGCTATTAGTGATGATACTGTA AGTAATTATAATGAAGACGATCTGATTTGTGAGAAACATGATGTAATTACTCATGATGGAGCGCATTTAG ATACATTTGAAGTAAGGCATAGGTCACAAGAAAGTATTGATCCCAAATACCAAAAATATATTATCAATTT GGTAGGGAATGGTATGTGTTATGAACATATCATTGACGATATAAAAGAAGATTCGAAGGCTCTTAAGGCC AATGTTATTGGTTTTAATCTTCGTGGTGTTGGTCAAAGTACAGGCAAAGCCAAATCAAGTGAGGATTTGG TTGCAGATGGTATTGCACAAGTGCAAAGACTATTAGATCAAGGTGTTTCGCCACAAAATATTACCCTGAA AGGTCATTCTCTTGGTGCAGGCGTGGCTTCCTTGGTAGCGCAACATTTTCATCAACTTGGACAGCCAATT AATCTATTTAATAGCCGTTCTTTCTCTACTATTACTAATTTCTTAGTAGGGCATATGCGTTTAGAGCGTG ATGAAATTGGTCGAGCAATAGGTCATAAAGACAGCACAGTAGGGACAATACTTGGATGGTTGGCTAAGCC CTTCATTAAATTCGGTGTTGCTTTAGCTAAATGGGAAATTAATGCAGGCAGTGCATTCAAGAGTGTTCCT GAAGCATATAAAGATTACATAGTGGTTAGGTCAAGAAAAGAGATAAGGGGCGAACGTATCGATGATGCTG TGATTCCACATTATGCATCTATCCATAAAGAACTGGCTTCTGAGCGGCATAAGAAAAAGGCGGAGATTGA TGAAGAAATTGCAAATCTGGATGATATCATTCGAAAAGCTGATCCTCTTGCGAAACCAGGGTTGGCTAAT GCAAGAGACGCTTTAGTCCAAGCTAGGGAAAAAATCAAAAGTGACAGAAAAATGGAGACTGATGTACAAT ATGCTAATGGTCATAATTCAGACTGGAATGCATTGCATAATCGATCAGGTAAGAGCGCGCAGACTTTCTT TAGAGAGTTTGTTCAAAGAACAGAAGCGGATCATGCCGTAAAAAGTATACCAGAAATAAATTAG |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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(2) Burstein D; Zusman T; Degtyar E; Viner R; Segal G; Pupko T (2009). Genome-scale identification of Legionella pneumophila effectors using a machine learning approach. PLoS Pathog. 5(7):e1000508. [PudMed:19593377] 
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| experimental literature |
| in silico analysis literature |