SecReT4
Effector Protein ID: 52841392
T4SS name [ID]Dot/Icm [5]
Gene symbol-
Locus taglpg1158
StrainLegionella pneumophila subsp. pneumophila str. Philadelphia 1
Repliconchromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon]
Location [Strand]1278130..1278900 [+]
Producthypothetical protein
Effector typeProtein
Descriptonlpg1158
T4CP requirementT4CP Depedent
Target/EffectionUnknown
UniProt IDQ5ZWC7
KEGG IDlpn:lpg1158
PDB IDNA
Domain hit(s) vs Pfam NA
Protein Sequence: 256 a.a.     [Download]
>gi|52841392|ref|YP_095191.1| hypothetical protein lpg1158 [Legionella pneumophila subsp. pneumophila str. Philadelphia 1]
MIIYLSIWLIIGMKELIAFIHDLYKDRTEKSVKFESKGRVIVSPLMSKDDAQELFKSLKEILPEEARLKV
RKSKQEPDQFRVVLFNPEKFFSFYAEHAAELLNRFKPLPTSSSGEEYCKWKYNPLSHLIEYTVPFSILDS
DTKAKVTDTHEEAIQSKVNQYNEKLRSIYPNLKIIGTNSVEDSSPDKFFLGSFNYNDYKIIKNLNNPASL
RQLAIGFFKEHPGHYTEEVAKKIPGDMKDEFTDIEPSSTKPSSTGS
-
Nucleotide Sequence: 771 bp     [Download]
>gi|52840256|ref|NC_002942.5|:1278130-1278900 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome
TTGATTATATATTTATCAATATGGTTGATAATTGGCATGAAAGAATTAATAGCTTTTATTCATGACTTGT
ATAAAGATCGTACTGAGAAATCTGTAAAATTTGAATCCAAGGGGAGAGTTATTGTATCTCCTTTGATGAG
TAAAGATGATGCCCAGGAATTATTTAAATCATTAAAAGAAATACTCCCTGAAGAGGCACGATTAAAGGTA
CGTAAGTCAAAGCAAGAACCAGATCAGTTTCGTGTCGTTCTCTTTAATCCTGAAAAGTTTTTTTCGTTTT
ATGCCGAGCATGCTGCAGAACTGTTAAATCGATTTAAACCATTACCGACATCTTCTTCAGGAGAGGAATA
TTGTAAATGGAAATATAATCCTTTATCACATCTAATAGAATATACTGTTCCGTTTTCAATTCTAGATTCT
GATACAAAAGCGAAAGTTACAGATACTCATGAAGAGGCTATACAATCAAAAGTAAATCAATATAACGAGA
AGTTACGGTCGATTTACCCTAATCTCAAAATTATCGGAACTAATTCAGTTGAAGACTCTAGTCCTGATAA
ATTTTTCTTAGGATCTTTTAATTATAATGATTATAAAATCATTAAGAATCTTAATAATCCTGCAAGTTTG
CGTCAATTAGCAATTGGATTTTTTAAAGAACATCCTGGTCATTATACAGAAGAAGTTGCTAAAAAAATAC
CAGGAGATATGAAGGATGAGTTTACTGATATTGAACCATCTTCCACTAAACCATCGTCAACCGGCAGCTA
A

Reference
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] in_silico
(2) Burstein D; Zusman T; Degtyar E; Viner R; Segal G; Pupko T (2009). Genome-scale identification of Legionella pneumophila effectors using a machine learning approach. PLoS Pathog. 5(7):e1000508. [PudMed:19593377] experimental in_silico
(3) Kubori T; Hyakutake A; Nagai H (2008). Legionella translocates an E3 ubiquitin ligase that has multiple U-boxes with distinct functions. Mol Microbiol. 67(6):1307-19. [PudMed:18284575] experimental
 
experimental experimental literature
in_silico in silico analysis literature