| Effector Protein ID: 52841204 |
 T4SS name [ID] | Dot/Icm [5] |
| Gene symbol | - |
| Locus tag | lpg0969 |
| Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
| Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 1063227..1063967 [+] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | RavK |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Unknown |
| UniProt ID | Q5ZWW5 |
| KEGG ID | lpn:lpg0969 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 246 a.a. [Download] |
| >gi|52841204|ref|YP_095003.1| hypothetical protein lpg0969 [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MVSLEHIQKLISECRKLGKDGLDNGTNGLIPELEIDVVPPSAFLGVGNNPAIFVNSKTYKLMRTTHEKWV ENKTIVFKSYLLSQPAIKIIGAIVHETGHAFNVAAKIPNTEANACIFEIEVLMRLFQVKSPLLLGCTELD MQSYFKSRLTDYNKCVKDCQCLAEMVEFITHQFKLDEVSISEKENQIPLLSISNKWPGLFAKKQIAPDMD KLLTSPVTITPEVKILFYQLVKEHFHSPETEIKLDI |
| - |
| Nucleotide Sequence: 741 bp [Download] |
| >gi|52840256|ref|NC_002942.5|:1063227-1063967 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome ATGGTAAGTTTGGAGCATATACAAAAACTTATTTCGGAATGTAGGAAGTTGGGTAAAGATGGACTTGATA ATGGTACTAATGGGTTAATCCCTGAATTGGAAATCGATGTTGTCCCTCCCAGTGCGTTTTTAGGGGTAGG TAATAATCCGGCAATTTTTGTAAATTCTAAAACATACAAGTTAATGCGTACAACCCATGAAAAATGGGTT GAAAACAAAACAATAGTTTTTAAAAGTTATTTGCTTTCCCAGCCGGCGATCAAAATTATTGGTGCTATTG TTCATGAAACTGGTCATGCTTTTAATGTGGCTGCCAAAATTCCCAATACTGAAGCAAATGCCTGTATTTT TGAAATTGAAGTGTTAATGAGGTTGTTTCAAGTTAAAAGCCCCTTGCTGCTAGGGTGTACGGAACTGGAT ATGCAATCTTATTTTAAATCACGGTTAACTGATTACAACAAATGTGTGAAAGACTGCCAATGTTTAGCTG AAATGGTCGAATTTATAACTCATCAATTTAAGCTGGATGAGGTATCAATTTCAGAGAAAGAAAACCAAAT CCCGCTTCTGTCTATTTCAAACAAATGGCCAGGCTTATTTGCAAAGAAACAGATTGCCCCTGACATGGAT AAATTATTGACTTCTCCTGTAACTATCACTCCAGAGGTTAAAATCCTGTTTTATCAATTGGTTAAAGAGC ATTTTCATTCTCCTGAAACAGAGATAAAGCTTGATATATAA |
| Reference |
(1) Liu Y et al. (2017). A Legionella Effector Disrupts Host Cytoskeletal Structure by Cleaving Actin. PLoS Pathog. 13(1):e1006186. [PudMed:28129393] 
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(2) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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| experimental literature |
| in silico analysis literature |