| Effector Protein ID: 52841180 |
 T4SS name [ID] | Dot/Icm [5] |
| Gene symbol | legL1 |
| Locus tag | lpg0945 |
| Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
| Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 1025948..1026838 [-] |
| Product | Gala protein type 1, 3 or 4 |
| Effector type | Protein |
| Descripton | LegL1 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Unknown |
| UniProt ID | Q5ZWY8 |
| KEGG ID | lpn:lpg0945 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | LRR_6 [PF13516], Evalue: 5.3e-30, Aligned region: 67..87 LRR_6 [PF13516], Evalue: 5.3e-30, Aligned region: 90..111 LRR_8 [PF13855], Evalue: 1.7e-13, Aligned region: 20..78 LRR_8 [PF13855], Evalue: 1.7e-13, Aligned region: 186..245 LRR_4 [PF12799], Evalue: 2.7e-12, Aligned region: 187..222 |
| Protein Sequence: 296 a.a. [Download] |
| >gi|52841180|ref|YP_094979.1| Gala protein type 1, 3 or 4 [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MVLTLSDLEKGYDKNLNQLSLSFLNLRDNDIPLLCEFLQNHPAITSLDLSHNDITANGVKLFVNKTSVSS LNISHNNIGPEGAQWLSEDNHITTLDVSFNEIGDEGVKALAANAKLITLYALYNKITKVGAGYLAQSNLK KIDLCFNSLEDEGVIALASNINIKELIASACDVSDIGAIELAKNNQLTLLILGKNAITDKSTLHFANNTS LSTLHLGSNQITAAGKKILETNTRITDLDLIGNPIEVHETDELNYSKKSPDSHSVFKFLQKFTFLSCMSP CQETAESDKGLNKKPN |
| - |
| Nucleotide Sequence: 891 bp [Download] |
| >gi|52840256|ref|NC_002942.5|:c1026838-1025948 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome TTGGTGTTAACATTATCGGATTTGGAAAAAGGCTATGATAAAAATCTTAATCAACTCTCATTATCCTTTT TAAATCTTAGAGATAATGACATACCACTGCTATGTGAGTTTCTTCAAAATCATCCTGCCATAACCAGTCT TGACCTGTCACATAATGATATTACAGCCAATGGTGTGAAGCTTTTTGTTAATAAAACATCGGTTTCATCC CTTAACATTAGCCATAATAATATTGGTCCGGAGGGTGCTCAATGGCTATCAGAAGATAACCACATTACTA CTTTAGATGTCAGTTTTAACGAGATTGGTGACGAGGGAGTTAAAGCTCTAGCCGCTAACGCCAAACTGAT AACCCTTTATGCACTTTATAATAAGATAACCAAAGTAGGAGCAGGCTATCTTGCTCAATCCAATCTTAAG AAAATCGATCTCTGCTTCAATAGTCTGGAAGATGAGGGGGTTATAGCATTAGCAAGTAATATCAATATAA AAGAGCTGATTGCAAGCGCTTGTGATGTCTCTGATATTGGAGCTATTGAATTAGCTAAAAACAATCAACT GACTTTACTTATTTTGGGAAAAAACGCGATAACCGATAAATCAACACTCCATTTTGCTAATAACACGTCT TTGAGTACCCTTCATCTGGGTAGTAATCAAATTACAGCAGCAGGTAAAAAAATACTTGAAACCAATACCA GGATAACGGACCTCGATTTAATCGGCAATCCAATTGAAGTGCATGAAACAGATGAACTAAATTATTCTAA AAAATCGCCAGACTCCCATAGTGTATTTAAGTTTTTGCAAAAATTTACTTTTCTCAGTTGTATGTCACCT TGTCAAGAAACCGCAGAAAGCGATAAAGGCTTAAATAAAAAACCGAATTAA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
|
(2) Burstein D; Zusman T; Degtyar E; Viner R; Segal G; Pupko T (2009). Genome-scale identification of Legionella pneumophila effectors using a machine learning approach. PLoS Pathog. 5(7):e1000508. [PudMed:19593377] 
|
| experimental literature |
| in silico analysis literature |