Effector Protein ID: 52840858 |
T4SS name [ID] | Dot/Icm [5] |
Gene symbol | sidA |
Locus tag | lpg0621 |
Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
Location [Strand] | 654121..655545 [-] |
Product | protein SidA |
Effector type | Protein |
Descripton | SidA |
T4CP requirement | T4CP Depedent |
Target/Effection | Unknown |
UniProt ID | Q5ZXW0 |
KEGG ID | lpn:lpg0621 |
PDB ID | NA |
Domain hit(s) vs Pfam | NA |
Protein Sequence: 474 a.a. [Download] |
>gi|52840858|ref|YP_094657.1| protein SidA [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MSKKYRTPIRLSDKMKTLKKNLQEQLTQSKSLGEQIHAGTTTASTITTGINHLFNVIASFLSSYRQIPLV GGVLQLVAILAKSISIVSDPEKSIAEKIISSILIAAIIALSIAAITLGGLAAAIIGTVIASTVTIMEGLG FFGKIAEKFQLANSYKMKKEFIDLVAKRIEPNNDKYNDLFEIRAIELQHELEKSYPNQIEQQQLKEELNF INAVLRKKNITPGNNKENDAYKLNQLYAKRAEQLKTLVDKIALINPTGKRAEQNKLLSEIKALQKEITKT DDSIEEIIAPLAKIERDNLKSTINLPLSYSTFAIAAASTLISIAGLLVVAGVIAAPPIMVPIMFAVGSVM AIIGLIKWTAEKMAEIEDAQLKAEKTAKHEDAVLDEALNVYEQQLNLELVSPSNPARQVKNILIVHDKVP ALSPTESTVSSLDSRFTLFGSSSREHTKIAEQKTTDTTNEQVPTTFDSISKPTR |
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Nucleotide Sequence: 1425 bp [Download] |
>gi|52840256|ref|NC_002942.5|:c655545-654121 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome ATGTCCAAAAAATATCGAACTCCCATCCGATTGTCAGACAAGATGAAAACTCTTAAAAAGAATCTTCAGG AGCAACTGACACAATCCAAATCGTTAGGCGAGCAAATTCATGCTGGAACTACCACAGCATCAACAATAAC AACGGGAATAAATCACTTGTTTAATGTTATTGCTTCCTTTTTAAGCTCCTACCGACAAATTCCACTGGTG GGTGGGGTTTTGCAATTGGTGGCCATATTAGCTAAATCAATCTCAATTGTGAGCGATCCGGAAAAATCTA TTGCTGAAAAAATAATATCTTCGATTCTAATTGCTGCTATTATCGCCCTGTCTATTGCAGCGATCACCCT CGGTGGATTGGCTGCCGCAATCATCGGGACAGTAATTGCTTCTACTGTAACCATCATGGAAGGATTGGGA TTTTTTGGGAAAATTGCTGAAAAATTTCAATTGGCAAATTCCTACAAAATGAAAAAAGAATTTATAGATC TTGTAGCGAAACGTATAGAGCCAAACAATGATAAATATAATGACTTATTCGAAATTCGTGCCATAGAACT CCAACATGAACTTGAGAAATCTTATCCCAATCAAATTGAACAGCAACAATTAAAAGAAGAGTTGAATTTC ATTAATGCGGTACTTAGGAAAAAAAATATCACCCCGGGCAACAACAAAGAGAATGACGCTTACAAACTAA ACCAACTCTATGCTAAACGCGCTGAGCAATTAAAAACTCTTGTAGATAAAATTGCTTTAATCAATCCAAC TGGAAAAAGAGCTGAGCAAAACAAACTTTTAAGCGAAATCAAAGCATTACAAAAAGAAATAACCAAAACC GACGATAGCATAGAAGAAATCATAGCCCCACTTGCTAAAATAGAACGAGACAATTTGAAATCTACCATTA ATTTGCCATTAAGTTACAGTACCTTTGCTATAGCAGCGGCCAGTACTTTAATATCGATAGCCGGCTTATT GGTGGTAGCTGGCGTGATTGCCGCACCTCCGATTATGGTCCCTATCATGTTTGCAGTAGGTAGTGTTATG GCAATCATTGGTTTAATCAAGTGGACCGCTGAAAAAATGGCTGAAATAGAGGACGCTCAATTAAAAGCAG AAAAAACTGCGAAACACGAGGATGCAGTTTTAGATGAAGCATTAAACGTTTATGAGCAACAATTAAATCT TGAGTTAGTCAGTCCTTCAAACCCTGCGAGACAGGTGAAAAATATATTAATAGTTCACGATAAAGTGCCT GCTTTGTCGCCAACTGAAAGTACTGTAAGCTCATTAGATTCCAGATTTACTTTATTTGGCTCATCTTCTC GAGAGCACACAAAAATAGCAGAACAGAAAACCACTGATACAACTAATGAACAAGTACCTACAACTTTTGA TTCCATATCCAAACCAACTCGTTAA |
Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] |
(2) Burstein D; Zusman T; Degtyar E; Viner R; Segal G; Pupko T (2009). Genome-scale identification of Legionella pneumophila effectors using a machine learning approach. PLoS Pathog. 5(7):e1000508. [PudMed:19593377] |
experimental literature |
in silico analysis literature |