| Effector Protein ID: 52840647 |
 T4SS name [ID] | Dot/Icm [5] |
| Gene symbol | legA9 |
| Locus tag | lpg0402 |
| Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
| Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 441321..443024 [+] |
| Product | ankyrin repeat-containing protein |
| Effector type | Protein |
| Descripton | AnkY/legA9 |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Unknown |
| UniProt ID | Q5ZYH0 |
| KEGG ID | lpn:lpg0402 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | Ank_2 [PF12796], Evalue: 1.8e-28, Aligned region: 434..501 Ank_2 [PF12796], Evalue: 1.8e-28, Aligned region: 441..533 Ank [PF00023], Evalue: 1.1e-20, Aligned region: 471..502 Ank [PF00023], Evalue: 1.1e-20, Aligned region: 504..535 Ank_4 [PF13637], Evalue: 3.2e-20, Aligned region: 436..483 Ank_4 [PF13637], Evalue: 3.2e-20, Aligned region: 472..524 Ank_5 [PF13857], Evalue: 6.3e-14, Aligned region: 461..508 Ank_5 [PF13857], Evalue: 6.3e-14, Aligned region: 495..542 Ank_3 [PF13606], Evalue: 3.5e-11, Aligned region: 470..498 Ank_3 [PF13606], Evalue: 3.5e-11, Aligned region: 504..530 |
| Protein Sequence: 567 a.a. [Download] |
| >gi|52840647|ref|YP_094446.1| ankyrin repeat-containing protein [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MHSLYLGVVKVMAKIILVYANCVNSTAKGDFALAGQIAKDLVREKTSDDIDVVLTSTLDGIARFESLYGK AVDGRVIIEGTSVGLCALELFESVDNEVVAFIEANRCKYAPSDILKRVLSPDSKFLFIGAANQKAIATGD KFTKSWLYISHKGDQPNVYEHFDEDDSLIQSVGLGDDRLGLPSLPKVDELPEMNSTQSQKIPSGEYGFMY LAAVHGIDDVYLMNQYMSLTEMGQYVLVGEYAKQSKEVQMVLHSLQYKGSSVSLTMPQIFFHDSVDNCLM RNMVSKSSGPLVVSTGVMSSIEAMQDGKLTYYQTMSNNTQFVASYLIAVKSICSSDTTLFGSMPKLIIDL SNLLFAEKPLKESQMKEIKSLLGMSSVTSRLGEMNKRIIAKANGTVAGELLSFIGKPKTTQSHKQCISVC MSLRKSGETTSPIFDQALRRAAAWGRLFELKVLIASMSTSDLNKKDKTGNQYTALHWAVMQGHLDCARLL VKSGASVDIQDKSGKSPLHYAIKRGDKETIKLLVQAGASLEIMDDSGAKPCDGSESWVPEYIKSCYEKSG HKSSSLF |
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| Nucleotide Sequence: 1704 bp [Download] |
| >gi|52840256|ref|NC_002942.5|:441321-443024 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome TTGCACAGTTTGTATCTAGGTGTGGTGAAAGTTATGGCTAAAATAATCTTGGTGTATGCTAATTGTGTTA ATTCAACTGCTAAAGGCGATTTTGCTCTGGCTGGGCAGATTGCCAAAGATTTAGTTAGAGAAAAAACTTC TGATGATATCGATGTGGTTTTAACCTCTACTTTGGATGGAATTGCAAGATTTGAAAGCCTTTATGGCAAA GCAGTTGATGGCCGTGTAATAATTGAAGGGACCAGCGTAGGCTTATGTGCCTTGGAATTATTTGAGTCGG TAGATAATGAAGTGGTGGCTTTCATTGAAGCAAACCGATGCAAATACGCACCAAGTGATATTCTAAAGCG AGTTCTCTCTCCTGACAGCAAATTTTTATTTATTGGAGCTGCTAACCAAAAGGCAATAGCAACAGGGGAT AAATTTACTAAATCCTGGTTGTACATAAGCCATAAAGGTGATCAGCCTAATGTTTATGAGCATTTTGACG AAGACGATTCTCTAATACAAAGTGTAGGTTTAGGTGATGATCGATTAGGATTACCATCCTTGCCAAAAGT CGATGAATTACCGGAGATGAACTCCACACAATCACAAAAAATACCAAGCGGCGAGTATGGATTTATGTAT CTTGCCGCTGTACATGGGATAGATGACGTTTATTTGATGAATCAATACATGTCTTTAACTGAGATGGGGC AATATGTTTTGGTGGGTGAATATGCCAAACAATCAAAAGAAGTTCAAATGGTTCTGCACAGTCTACAGTA TAAAGGTAGTTCGGTATCACTAACGATGCCTCAGATTTTCTTCCATGATTCGGTCGATAATTGTTTAATG CGAAACATGGTTTCAAAGTCTTCTGGTCCTTTGGTTGTTTCCACAGGGGTTATGAGTTCTATTGAGGCGA TGCAAGATGGTAAATTAACGTATTATCAGACAATGTCTAATAACACGCAATTCGTGGCTTCTTATTTGAT TGCTGTGAAATCCATTTGCTCCAGTGATACAACGTTATTTGGGTCTATGCCGAAATTAATTATCGATTTG TCTAATTTGCTTTTCGCAGAAAAACCGTTGAAAGAAAGTCAAATGAAAGAAATTAAATCTCTCTTAGGTA TGTCGTCAGTTACTAGTCGCTTGGGAGAAATGAATAAAAGAATCATTGCAAAAGCAAACGGGACTGTTGC TGGTGAGCTTTTAAGCTTTATTGGAAAACCTAAAACGACGCAATCACATAAACAATGCATCAGCGTTTGC ATGTCTCTTCGCAAGAGTGGTGAAACTACGTCGCCTATTTTTGATCAAGCATTACGCAGAGCAGCAGCTT GGGGTCGCTTGTTTGAATTGAAGGTGTTGATTGCATCAATGTCAACTTCTGATTTAAATAAAAAAGATAA AACAGGTAATCAATACACAGCACTTCATTGGGCTGTGATGCAGGGGCATTTAGATTGTGCAAGATTATTA GTTAAATCTGGCGCCTCTGTCGATATTCAAGACAAGTCTGGTAAATCGCCTTTACACTATGCGATTAAAA GAGGAGATAAAGAAACCATTAAATTATTGGTTCAAGCAGGAGCTTCTTTGGAAATTATGGATGATTCAGG AGCAAAACCTTGTGATGGATCAGAGTCTTGGGTTCCTGAGTATATTAAATCCTGTTATGAGAAAAGTGGC CACAAATCTAGTAGCTTATTTTAA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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(2) Burstein D; Zusman T; Degtyar E; Viner R; Segal G; Pupko T (2009). Genome-scale identification of Legionella pneumophila effectors using a machine learning approach. PLoS Pathog. 5(7):e1000508. [PudMed:19593377] 
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| experimental literature |
| in silico analysis literature |