| Effector Protein ID: 52840489 |
 T4SS name [ID] | Dot/Icm [5] |
| Gene symbol | sidE |
| Locus tag | lpg0234 |
| Strain | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 |
| Replicon | chromosome [GenBank: NC_002942] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 272577..277121 [-] |
| Product | protein SidE |
| Effector type | Protein |
| Descripton | SidE/laiD |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Unknown |
| UniProt ID | Q5ZYX7 |
| KEGG ID | lpn:lpg0234 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | SidE [PF12252], Evalue: 0, Aligned region: 20..1455 |
| Protein Sequence: 1514 a.a. [Download] |
| >gi|52840489|ref|YP_094288.1| protein SidE [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] MLIFKSQILILKYLSRSCVMPKYVEGIELTQEGMHAIFERMGHPNITSGTIYNGEPTIDKGALDRQGFMP VLTGVSPRQDSGHWIMLIKGQGNQYFLFDPLGESSGKYYQNILAKKLPGATLSVIPNNAGLNMGLCGYWV ASVGLRAHAALTQPIPPSLRNLGQTITQEMRDELTQDGSEKITQWLRAVGNEFPDGDIQPDATALRRATE KNVRIDEFQPVLTGTSPKEISINPTAPQEVSVPTWNGFSLYTDETVRNAARYAYDNYLGKPYTGTVEATP VNFGGQMVYRQHHGLAHTLRTMAYAEIIVEEARKAKLRGESLKTFADGRTLADVTPEELRKIMIAQAFFV TGRDDEESSKNYEKYHEQSRDAFLKYVEENKSTLIPDVFKDEKDVKFYADVIEDKDHKWADSPAHVLVNQ GHMVDLVRVKQPPESYLEYYFSQLQPWIGSTATEAVFATQRQFFHATYEAVAGFDSENKEPHLVVDGLGR YVIGQDGNPIREESDDEDEEESGELKFFSQKKKLEENQRYMRVDEYLKLDEVQKRFPGAGKKLDGGLPGL KEYQYLQRLNSINRARCENDVDFCLGQLQTAHHQTKITPIKRAFQSSSEKARRQPNMDEIAAARIVQQIM ANPDCIHDDHVFLNGQKLEEKFFRDLLAKCDMAIVGSLLNDTDIRNIDTLMQHERNTEFHSTDAKAKPVK LGETWEKTIRSGGGVTQIKHDLIFLMQNDAWYHTRVNAIAQNRDKDSTFKEVLITALMTPLTNKSLMDTS RSPAPKTLFRGLDLSEEFKNKLINQAETIIANTTEHLFTDLSTEAFKQIKLNDFSQVSARTCASTSTNIE VPRTIFGSNTIFEILDPDGLLHPKQVGTHVSGSESEYSIYLPEDVALVPIKVSFDGKTGKGKDRHIFTLV AVKSPDFTPRHESGYAVGPLLKMQTPKLEEIQRLVEQAREEPDLERVFNLQSRVARQAKFSTESGYKTFL NEKVAPVLEQSLNGLLDNNVTILGKVLSAFPSDGQWSAFNSVEARQMKIQMDAIKQMVEKKAVLEGQILP ALAQCQNALEKQNIAGALQALRNIPSEKEMQTMLSISGGLRGQIQRAKQDLTETLEPLQRAITAKLVSDQ EKVKVRYEKLIAGIPQQIADLEKAELADLAKVKKVVSRFNHLQEELKLLRNEKIRMHTGSEKVDFSDIAQ LEAQLQKIHTKLYDAYLVELTKEISALVKEKPKNLADVKRMVSNFYAMSADIEQLRQEKIKEHGESKDPI DMSDIDKLKEELQKINQFLVKAMGTNIRVSLNQMEVKTFDAQEKEAQQNLKQLDALINKLESSDAVQKQK EELEKLNQLLVEKRKAYPAMVQLQFRSEALIIHLRELCEAHQAQMAKTRNVRAQEITNGRWKVQWLTDWV GLTTDERVTLANKEKELAKFKEDLNNDEYDLQELISNLAEKNPSELEEAIGISKESAQKLHKLLTHLNHS TTFMSKIEQRLQSIDELLNEFGKQAPRTEMIKTVEEKQGTLLRL |
| - |
| Nucleotide Sequence: 4545 bp [Download] |
| >gi|52840256|ref|NC_002942.5|:c277121-272577 Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome GTGCTGATTTTTAAGTCACAAATATTAATTTTAAAGTATTTATCCAGGAGTTGTGTAATGCCTAAGTACG TTGAAGGGATAGAATTAACCCAAGAAGGGATGCATGCTATTTTTGAGCGCATGGGACATCCAAATATTAC CAGCGGTACTATCTACAACGGAGAGCCTACAATTGATAAAGGTGCTCTTGACAGGCAAGGCTTTATGCCA GTATTGACCGGGGTCAGCCCAAGGCAAGACTCGGGACATTGGATTATGTTAATTAAAGGTCAAGGCAATC AATATTTTCTCTTTGACCCGCTGGGAGAAAGCTCGGGAAAATATTACCAAAATATTTTAGCTAAAAAACT ACCTGGCGCTACGCTTTCTGTTATTCCTAATAATGCTGGATTAAATATGGGATTATGCGGCTATTGGGTT GCCTCAGTTGGTTTAAGAGCTCATGCGGCATTAACCCAACCTATTCCCCCTTCTTTAAGAAATCTGGGTC AAACCATTACCCAGGAAATGCGAGATGAACTAACACAAGATGGAAGCGAAAAAATTACACAATGGTTACG TGCCGTTGGCAATGAATTTCCAGATGGTGATATACAACCTGATGCCACAGCCTTAAGACGTGCTACTGAA AAGAATGTACGTATTGATGAGTTTCAGCCTGTTTTAACTGGAACATCACCTAAAGAAATTTCGATAAATC CTACTGCTCCTCAAGAAGTATCCGTTCCCACGTGGAATGGTTTTTCCTTATATACTGATGAAACCGTGAG AAATGCAGCCAGATACGCGTATGATAATTACTTGGGAAAACCTTATACCGGTACAGTAGAAGCGACACCT GTCAATTTTGGTGGGCAAATGGTGTACAGACAACACCATGGTCTTGCCCACACATTGCGCACCATGGCCT ATGCGGAAATCATTGTTGAGGAAGCGCGAAAAGCAAAATTAAGGGGTGAATCATTAAAAACATTTGCTGA TGGTCGTACTCTGGCGGATGTCACGCCTGAAGAATTGAGAAAAATCATGATCGCCCAGGCCTTCTTTGTC ACTGGAAGAGACGATGAAGAATCCTCCAAGAATTATGAAAAATACCACGAACAAAGCCGAGATGCTTTTT TGAAGTATGTCGAAGAGAATAAATCCACTTTAATTCCTGATGTATTCAAAGATGAAAAAGATGTCAAATT CTATGCTGATGTGATTGAAGATAAAGATCATAAATGGGCAGATTCACCGGCGCATGTCCTGGTCAATCAG GGCCATATGGTTGATTTGGTCAGAGTAAAACAACCCCCTGAATCTTACCTGGAATACTATTTTTCACAAC TTCAACCCTGGATAGGTTCAACAGCTACGGAAGCTGTTTTTGCGACACAGAGACAATTTTTCCATGCCAC CTATGAAGCAGTTGCGGGCTTTGATAGCGAAAACAAAGAACCTCATCTAGTGGTCGATGGTTTAGGACGC TATGTGATTGGACAAGATGGCAATCCAATACGAGAAGAATCTGATGACGAAGACGAGGAAGAATCAGGTG AATTAAAATTTTTCTCACAAAAAAAGAAACTCGAGGAAAACCAACGTTACATGCGCGTTGATGAATATTT AAAACTTGATGAGGTCCAAAAGCGATTCCCTGGCGCTGGTAAAAAACTCGATGGGGGACTGCCTGGACTG AAAGAATATCAATATTTACAGCGCTTGAACTCAATAAACAGAGCACGGTGTGAAAACGATGTCGACTTTT GTTTGGGACAATTACAAACGGCACATCATCAAACCAAAATCACTCCGATAAAGAGAGCATTTCAATCGAG TTCTGAGAAAGCGCGAAGACAACCCAATATGGATGAAATTGCTGCTGCACGTATTGTTCAGCAAATCATG GCCAATCCTGATTGTATCCATGACGATCATGTCTTCCTTAACGGTCAAAAACTGGAAGAAAAATTCTTTC GTGATTTGTTGGCGAAATGTGACATGGCTATTGTAGGGTCGCTATTAAACGACACAGACATTAGAAATAT CGATACCTTAATGCAACATGAGAGAAACACAGAATTTCACTCAACCGATGCCAAAGCAAAACCGGTGAAA CTGGGAGAAACATGGGAAAAAACAATCAGATCGGGTGGTGGGGTTACCCAGATAAAACATGATTTAATTT TCCTCATGCAAAATGATGCCTGGTACCATACTCGAGTCAATGCGATTGCACAAAACCGGGATAAAGATTC AACATTCAAAGAAGTGTTGATTACCGCTTTAATGACACCATTGACTAACAAATCATTGATGGATACATCA CGTTCCCCGGCCCCCAAAACGCTATTCCGTGGATTGGATCTGTCAGAAGAGTTTAAAAATAAATTAATTA ACCAGGCTGAAACCATAATTGCCAATACGACAGAACATCTCTTTACTGATCTATCGACAGAAGCCTTTAA ACAAATCAAATTAAATGACTTTAGCCAGGTTTCTGCTAGAACTTGTGCCAGTACTTCCACTAACATTGAA GTTCCCAGGACAATCTTTGGCTCCAATACCATCTTTGAAATACTTGATCCTGATGGTTTATTACACCCCA AACAAGTTGGAACCCATGTATCAGGGTCAGAAAGTGAATATTCCATTTATTTGCCAGAAGATGTTGCCTT GGTTCCAATCAAAGTAAGCTTTGATGGAAAAACAGGTAAAGGCAAAGACCGACATATTTTTACTTTAGTT GCGGTAAAAAGCCCCGATTTCACGCCAAGGCATGAAAGTGGTTATGCGGTTGGTCCTCTTTTGAAAATGC AAACGCCAAAATTAGAAGAAATTCAAAGATTAGTTGAGCAAGCAAGGGAAGAGCCTGACCTGGAAAGGGT ATTCAATTTACAATCGAGAGTAGCAAGACAAGCCAAATTCTCCACTGAATCAGGATATAAAACGTTTCTG AATGAAAAGGTGGCGCCTGTGTTGGAACAAAGCCTCAATGGCCTCTTGGACAATAATGTAACCATTCTAG GCAAAGTATTATCAGCATTCCCTTCAGACGGCCAATGGTCTGCCTTTAATTCAGTTGAAGCAAGGCAAAT GAAAATACAGATGGATGCCATTAAGCAAATGGTTGAAAAGAAAGCCGTCCTCGAAGGTCAAATTCTCCCT GCCTTGGCTCAATGCCAAAATGCTTTGGAGAAACAAAATATTGCAGGTGCATTACAAGCACTTAGAAACA TCCCTTCTGAAAAAGAAATGCAAACCATGCTGTCAATTAGTGGTGGTTTGAGAGGACAAATCCAGCGTGC CAAGCAAGATTTGACTGAAACTCTGGAGCCACTTCAACGCGCTATAACTGCTAAATTGGTAAGCGATCAA GAAAAAGTGAAAGTGCGTTATGAAAAACTGATAGCAGGCATACCTCAACAGATCGCCGATCTTGAAAAAG CAGAACTCGCTGATCTTGCCAAGGTTAAAAAAGTGGTCTCTCGTTTTAATCACCTGCAAGAAGAATTAAA ATTATTGCGTAATGAAAAAATTCGCATGCACACTGGCTCTGAAAAAGTCGATTTTTCAGATATCGCACAA TTAGAGGCGCAACTACAAAAAATCCATACTAAATTATATGACGCCTATTTGGTTGAATTAACCAAAGAAA TTTCAGCACTGGTTAAAGAAAAACCGAAAAACCTGGCCGACGTGAAAAGGATGGTTTCGAATTTCTACGC TATGTCAGCTGATATTGAACAATTGCGTCAGGAAAAGATAAAAGAACACGGTGAGTCAAAAGATCCGATT GATATGTCTGATATTGATAAATTAAAGGAAGAACTACAAAAAATTAATCAATTTTTAGTGAAGGCGATGG GAACTAATATCAGGGTTTCACTGAATCAAATGGAAGTAAAAACTTTTGATGCCCAGGAAAAAGAAGCACA ACAAAATTTGAAGCAACTAGACGCACTGATTAATAAATTGGAAAGTTCTGATGCTGTACAGAAACAAAAA GAAGAACTCGAAAAATTAAACCAATTGCTTGTCGAGAAGCGAAAAGCCTATCCCGCAATGGTGCAGTTGC AATTCAGGAGTGAAGCATTAATTATCCATTTACGTGAATTATGTGAAGCTCATCAAGCTCAAATGGCTAA AACAAGAAATGTAAGGGCGCAAGAAATCACTAATGGACGATGGAAAGTACAATGGTTGACTGATTGGGTT GGTTTAACTACAGATGAGCGGGTAACTCTTGCCAATAAAGAGAAAGAATTGGCTAAATTCAAGGAAGATT TAAATAATGACGAGTATGATTTGCAGGAACTCATCAGTAACCTGGCTGAGAAAAACCCGTCAGAATTGGA AGAAGCCATAGGGATATCTAAAGAGAGCGCTCAGAAATTGCATAAACTGTTAACTCATCTAAACCACAGT ACAACATTTATGAGTAAAATCGAGCAACGATTACAGTCTATTGATGAGCTATTAAACGAGTTTGGCAAGC AAGCGCCCCGAACTGAAATGATAAAAACTGTTGAGGAAAAACAAGGAACTCTCTTAAGATTGTAA |
| Reference |
(1) Gomez-Valero L; Rusniok C; Cazalet C; Buchrieser C (2011). Comparative and functional genomics of legionella identified eukaryotic like proteins as key players in host-pathogen interactions. Front Microbiol. 2:208. [PudMed:22059087] 
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(2) Burstein D; Zusman T; Degtyar E; Viner R; Segal G; Pupko T (2009). Genome-scale identification of Legionella pneumophila effectors using a machine learning approach. PLoS Pathog. 5(7):e1000508. [PudMed:19593377] 
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| experimental literature |
| in silico analysis literature |